Clinical trials: Acute Coronary Disease
Myocardial Ischemia, Heart Failure
sST2 Biomarker Level in Acute/Chronic Coronary Syndrome After Revascularization
The role of soluble circulating suppression of tumorigenicity 2 biomarker (sST2) in the ischemic heart disease patient is a debatable point.
- Conditions
- Myocardial Ischemia, Heart Failure, Coronary Intervention
- Trial name
- ST2 (NCT05686057)
- Testing
- percutanous coronary angiography with stenting
- Where
- 2 sites in Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Myocardial Infarction (MI), Acute Coronary Syndrome (ACS)
Ticino Artificial InTelligence integrAtioN for Occlusion Myocardial Infarction
The goal of this clinical trial is to evaluate whether an artificial intelligence (AI)-based ECG interpretation tool improves the early diagnosis and treatment of occlusion myocardial infarction (OMI) in adults presenting with…
- Trial name
- TITAN-OMI (NCT07077057)
- Testing
- AI-assisted ECG interpretation (PMcardio)
- Where
- Switzerland
- Volunteers
- 500 people
- Sponsor
- Cardiocentro Ticino
Acute Coronary Syndrome
Serum Soluble ST2 and Plaque Vulnerability in Patients With Acute Coronary Syndrome
This study aimed to assess the association between serum sST2 level and plaque vulnerability in ACS patients. It is hypothesized that serum sST2 level may be related to plaque components and closely associated with plaque…
- Trial name
- NCT04797819
- Testing
- Coronary plaque components
- Where
- China
- Volunteers
- 120 people
- Sponsor
- RenJi Hospital
Heart Disease, Acute Renal Failure
N-Acetylcysteine for Preventing Renal Injury After Cardiac Surgery
Cardiac surgery improves the survival and quality of life of people with heart disease. Nonetheless, several complications continue to adversely affect outcomes following cardiac surgery.
- Trial name
- NCT00188630
- Testing
- N-acetylcysteine, 5% dextrose solution
- Where
- Canada
- Volunteers
- 176 people
- Sponsor
- University Health Network, Toronto
Acute Coronary Syndrome
Efficacy and Safety Study of Ticagrelor
The purpose of this study is to compare the efficacy and safety of ticagrelor with clopidogrel
- Trial name
- NCT01812330
- Testing
- Clopidogrel, Ticagrelor
- Where
- China
- Volunteers
- 180 people
- Sponsor
- General Hospital of Chinese Armed Police Forces
Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple
AI Assisted Detection of Chest X-Rays
This study has been added as a sub study to the Simulation Training for Emergency Department Imaging 2 study (ClinicalTrials.gov ID NCT05427838).
- Conditions
- Pulmonary Nodules, Solitary, Pulmonary Nodules, Multiple, Pulmonary Consolidation, Pneumothorax
- Trial name
- AID-CXR (NCT06075836)
- Testing
- Cases reading, Ground truthing
- Where
- United Kingdom
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Oxford University Hospitals NHS Trust
NAFLD, ACS - Acute Coronary Syndrome
Prevalence of NAFLD in ACS Patients
Addressing CVD risk in patients with NAFLD is the aspect of the disease most amenable to medical management and so improving long-term clinical outcomes.
- Trial name
- PADAC (NCT05378321)
- Testing
- Non-invasive diagnostic testing
- Where
- Belgium
- Volunteers
- 225 people
- Sponsor
- Ziekenhuis Oost-Limburg
Acute Coronary Syndrome
Trial for the Use of Pretest Probability to Reduce Unnecessary Testing for Low-Risk Patients With Chest Pain
The purpose of this study is to evaluate if the implementation of quantitative pretest probability assessment will significantly reduce the unnecessary use of the intra-emergency department chest pain center.
- Trial name
- NCT00243516
- Testing
- PREtest Consult
- Where
- United States
- Volunteers
- 400 people
- Sponsor
- PREtest Consult
Any Condition Underlying Critical Illness
SWedish Intensive Care Biobank
The goal of this observational study is to understand the genetic and molecular risk factors for developing critical illness in adult intensive care unit (ICU) patients in Sweden.
- Trial name
- SWIC-B (NCT07582601)
- Volunteers
- 25,000 people
- Sponsor
- Uppsala University
Cardiovascular Diseases
Chronic and Acute Effects of Smoking on the Left and Right Ventricular Relaxation in Young Healthy Smokers
Impairment of relaxation, the early phase of ventricular diastole is the first stage of heart diastolic dysfunction. Left ventricular diastolic function can be determined noninvasively by Echo- Doppler - derived mitral valve flow…
- Trial name
- NCT00395928
- Where
- Poland
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
Acute Kidney Injury
Acute Kidney Injury After Cardiac Surgery Based on KDIGO Criteria
The aim of this study was to apply the acute kidney injury criteria based on KDIGO classification in a population of patients undergoing cardiac surgery [coronary artery bypass grafting (CABG) or cardiac valve surgery (CVS)] and…
- Trial name
- NCT00777465
- Where
- Brazil
- Volunteers
- 2,804 people
- Sponsor
- Hospital de Base
Heart Failure; With Decompensation
Remote Dielectric Sensing (ReDS) Assisted Diuresis in Acute Decompensated Heart Failure
This study evaluates the use of a wearable vest capable of non-invasively measuring lung fluid content in hospitalized patients with heart failure
- Trial name
- RADAR-HF (NCT03586336)
- Testing
- ReDS-Guided, Usual Care
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of California, San Francisco
Acute Coronary Syndrome
Effect of Dalcetrapib vs Placebo on CV Risk in a Genetically Defined Population With a Recent ACS
A placebo-controlled, randomized, double-blind, parallel group, phase III multicenter study in subjects recently hospitalized for ACS and with the appropriate genetic profile.
- Trial name
- dal-GenE (NCT02525939)
- Testing
- dalcetrapib
- Where
- 557 sites in United States, Argentina and 30 more
- Volunteers
- 6,147 people
- Sponsor
- DalCor Pharmaceuticals
Acute Coronary Syndrome, Myocardial Infarction
Outcome of Longterm Antithrombotic Therapy in Acute Coronary Syndrome Patients
This observational study will based on the Register of Information and Knowledge About Swedish Heart Intensive Care Admissions (RIKS-HIA) and the Swedish Coronary Angiography and Angioplasty Registry (SCAAR) which since 2009 are…
- Trial name
- NCT01623700
- Where
- Sweden
- Volunteers
- 78,000 people
- Sponsor
- Uppsala University
Acute Coronary Syndrome
Protective Effect of Early High Dose stATins On Cardiovascular and Renal Events in Acute Coronary Syndrome
Registration of all ACS patients (STEMI and NSTEMI) admitted to the cardiology ward and scheduled for early invasive strategy. The aim is to evaluate the protective effects of early (on admission) high-dose high-potency statin…
- Trial name
- PRATO-ACS (NCT04087200)
- Where
- Italy
- Volunteers
- 2,500 people
- Sponsor
- Centro Cardiopatici Toscani
Heart Failure
Left Atrial Pressure Monitoring to Optimize Heart Failure Therapy
The purpose of this clinical study is to evaluate the safety and clinical effectiveness of use of a physician-directed, patient self-management system, guided by left atrial pressure measurements, for use in patients with heart…
- Trial name
- LAPTOP-HF (NCT01121107)
- Testing
- Left Atrial Pressure Monitoring System, Patient Advisory Module
- Where
- 64 sites in United States, New Zealand
- Volunteers
- 486 people
- Sponsor
- Abbott Medical Devices
Infective Endocarditis
18-FDG PET/CT Imaging and Clinical Decisions in Infective Endocarditis
The purpose of this study is to assess the impact of 18-FDG positron emission tomography (PET)/computed tomography (CT) imaging in the management of patients with suspected or proven IE in detecting cardiac valve damages and…
- Trial name
- TEPvENDO (NCT02287792)
- Testing
- 18-FDG PET/CT scan
- Where
- France
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Acute Coronary Syndrome, STEMI
Chewing Ticagrelor Versus Prasugrel in ST-elevation Myocardial Infarction - A Platelet Reactivity Study
To examine the efficacy of chewing Ticagrelor versus Prasugrel in ST-elevation Myocardial Infarction (STEMI) patients on platelet reactivity.
- Trial name
- NCT03016611
- Testing
- Chewing Ticagrelor LD, Chewing Prasugrel LD
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Sheba Medical Center
Chest Pain
Low-Dose Coronary Computed Tomographic Angiography for Early Triage of Acute Chest Pain
This study is to see whether the low-dose coronary computed tomographic angiography (CCTA) protocol is as safe and efficacious as conventional-dose protocol in early triage of acute chest pain.
- Trial name
- NCT01770444
- Testing
- Low-dose Cardiac CT protocol, Conventional cardiac CT protocol
- Where
- 3 sites in South Korea
- Volunteers
- 681 people
- Sponsor
- Seoul National University Hospital
Myocardial Infarction
Antiplatelet Therapy Effect on Extracellular Vesicles in Acute Myocardial Infarction
Platelet activation and aggregation leads to myocardial infarction. Platelet P2Y12 receptors are essential for platelet activation.
- Trial name
- AFFECT EV (NCT02931045)
- Testing
- Ticagrelor, Clopidogrel
- Where
- 2 sites in Netherlands, Poland
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Medical University of Warsaw
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