Clinical trials: Acute Myocardial Infarction, completed
Myocardial Infarction, Acute, Myocardial Infarction
A Behavioral Economics-Based Telehealth Intervention to Improve Post-MI Medication Adherence
The proposed study is a pilot randomized clinical trial (RCT). Participants in the intervention arm will participate in a 90-day adherence promotion program based on the theory of behavioral economics and administered through the…
- Trial name
- NCT03022266
- Testing
- Financial Incentive and Mobile Phone App
- Where
- United States
- Volunteers
- 130 people
- Sponsor
- Wellth Inc.
Acute Myocardial Infarction
Bezafibrate for Hyperfibrinogenemia in Acute Myocardial Infarction
Introduction: Plasma fibrinogen levels have been identified as an important risk factor for cardiovascular diseases and could have a prognostic value.
- Trial name
- BEZAFIBRAMI (NCT02291796)
- Testing
- Bezafibrate
- Volunteers
- 100 people
- Sponsor
- Instituto Mexicano del Seguro Social
Acute Myocardial Infarction (AMI)
AI-ECG for Predicting CMR-Defined Myocardial Injury in Acute Myocardial Infarction
This retrospective, single-center external validation study evaluates whether two commercially approved artificial intelligence-enhanced electrocardiography (AI-ECG) algorithms (AiTiA LVSD and AiTiA MI; Medical AI Co., Ltd.)…
- Trial name
- NCT07751809
- Where
- South Korea
- Volunteers
- 461 people
- Sponsor
- Yonsei University
Chest Pain, Acute Coronary Syndrome
Improving the Accuracy of Referrals of Patients With Chest Pain
This is a multicenter, prospective, investigator-initiated, randomized controlled trial aiming to reduce the percentage of non-cardiac chest pain (NCCP) patients admitted to the cardiac emergency department (ED) by performing the…
- Conditions
- Chest Pain, Acute Coronary Syndrome, Myocardial Infarction, Myocardial Ischemia
- Trial name
- URGENT2 (NCT04904107)
- Testing
- modified HEART score (including POC hs cTnI analysis), Standard care and triage according to the local (EMT)protocol.
- Where
- 2 sites in Netherlands
- Volunteers
- 852 people
- Sponsor
- VieCuri Medical Centre
Myocardial Infarction
OMEGA-Study: Effect of Omega 3-Fatty Acids on the Reduction of Sudden Cardiac Death After Myocardial Infarction
Cardiovascular disease (CVD) is the leading cause of death in North America and Europe. The major cause of CVD is atherosclerosis like coronary artery disease (CAD).
- Trial name
- OMEGA (NCT00251134)
- Testing
- Zodin (drug)
- Where
- 10 sites in Germany
- Volunteers
- 3,800 people
- Sponsor
- Stiftung Institut fuer Herzinfarktforschung
Myocardial Infarction
Acute Myocardial Infarction by Penetrating Cardiac Trauma
Patients with a cardiac stab wound could be complicated by a posttraumatic acute myocardial infarction (PAMI). Traditionally, the investigators can explain it by the occlusion of a coronary artery; but the PAMI isn´t constantly…
- Trial name
- NCT01182064
- Where
- Colombia
- Volunteers
- 51 people
- Sponsor
- Universidad de Antioquia
Acute Myocardial Infarction
68 Ga-NODAGA-E[c(RGDγK)]2: Positron Emission Tomography Tracer for Imaging of Myocardial Angiogenesis
The aim is to examine the expression of αvβ3 integrin using a novel selective radiotracer in patients with myocardial infarction and investigate if it is a suitable tool for predicting myocardial recovery and thus prognosis.
- Trial name
- NCT03445884
- Testing
- 68Ga-NODAGA-E[c(RGDyK)]2
- Where
- Denmark
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Acute Coronary Syndrome, STEMI
The Effect of Colchicine on Inflammation in ACS Patients
This study will evaluate whether the anti-inflammatory effect of colchicine is beneficial in ACS patients
- Trial name
- NCT06054100
- Testing
- Colchicine Tablets
- Where
- Egypt
- Volunteers
- 88 people
- Sponsor
- Ain Shams University
Acute Myocardial Infarction
Does Heme Oxygenase-1 Induction Ameliorate Cardiac Injury After Myocardial Infarction?
Rationale: A safety and dose defining study in which the investigators hypothesize that in patients with acute coronary syndrome without ST-elevation (NSTEMI) treatment with heme arginate results in better clinical outcome by…
- Trial name
- HAEM (NCT00483587)
- Testing
- Heme arginate
- Where
- Netherlands
- Volunteers
- 15 people
- Sponsor
- University Medical Center Groningen
Myocardial Infarction
Safety Study of Bone Marrow Derived Cells to Treat Damaged Heart Muscle
Certain types of cells located in bone marrow may help the body recover after an injury. These cells may be able to help the body repair heart muscle that has been damaged from a heart attack.
- Trial name
- NCT00361855
- Testing
- NX-CP105
- Where
- 5 sites in United States
- Volunteers
- 18 people
- Sponsor
- Neuronyx
Myocardial Infarction
Safety of TG100-115 for Heart Attack Treated With Angioplasty
TG100-115 is able to reduce the size of heart attacks in pre-clinical models. The hypothesis of this study is that TG100-115 can be given safely to patients who suffer a heart attack and undergo angioplasty to restore blood flow.
- Trial name
- NCT00103350
- Testing
- TG100-115
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- TargeGen
Acute Coronary Syndrome, Myocardial Infarction
A Study of Elecsys® Troponin T hs Gen 6 in Participants With Symptoms of Acute Coronary Syndrome
This prospective, non-interventional, single arm, longitudinal cohort multicenter study will recruit approximately 5600 consecutive all-comers, consisting of patients with signs and symptoms of acute coronary syndromes (ACS) who…
- Trial name
- PERFORM-TSIX (NCT06734117)
- Testing
- Elecsys® Troponin T hs Gen 6, Blood sample collection
- Where
- 50 sites in United States, Austria and 9 more
- Volunteers
- 5,429 people
- Sponsor
- Hoffmann-La Roche
Acute Coronary Syndrome, Angina Pectoris
Mersey Acute Coronary Syndrome Rule-Out Using High Sensitive Troponin
The aim of this observational study is twofold. The primary hypothesis being tested is that initial(first) high sensitivity Tn <5ng/l (limit of detection) combined with an ECG with no ischaemic changes is superior as an…
- Conditions
- Acute Coronary Syndrome, Angina Pectoris, Cardiovascular Diseases, Chest Pain
- Trial name
- MACROS (NCT02581540)
- Volunteers
- 3,054 people
- Sponsor
- Liverpool University Hospitals NHS Foundation Trust
Acute Myocardial Infarction
Ticagrelor for PCI Post Thrombolysis
Ticagrelor is a first line therapy along with aspirin for patients undergoing primary PCI for STEMI. However, many patients are still treated with fibrinolytic therapy and the safety and efficacy of Ticagrelor has not been…
- Trial name
- SETFAST (NCT01930591)
- Testing
- Ticagrelor, Clopidogrel
- Where
- 5 sites in Canada
- Volunteers
- 140 people
- Sponsor
- Unity Health Toronto
Acute Myocardial Infarction
Using Higher Cut-off Values to Diagnose Acute Myocardial Infarction in Patients With Elevated Hs-cTnT Concentrations
High-sensitive cardiac troponin T (hs-cTnT) is a cornerstone for diagnosing acute myocardial infarction (AMI). However, it is often challenging to diagnose AMI in patients with elevated hs-cTnT before a rise or fall of hs-cTnT…
- Trial name
- NCT06059079
- Testing
- No Intervention
- Where
- China
- Volunteers
- 80,000 people
- Sponsor
- The First Affiliated Hospital with Nanjing Medical University
Acute Myocardial Infarction, Coronary Artery Disease
Complete vs Culprit-only Revascularization to Treat Multi-vessel Disease After Early PCI for STEMI
To determine whether, on a background of optimal medical therapy, including ticagrelor, opening of all suitable narrowings or blockages found at the time of primary PCI for an acute heart attack is better than treating only the…
- Trial name
- COMPLETE (NCT01740479)
- Testing
- Complete Revascularization Strategy
- Where
- Canada
- Volunteers
- 4,042 people
- Sponsor
- Population Health Research Institute
Acute Coronary Syndrome, Myocardial Infarction
High-Sensitivity Troponin in the Evaluation of Patients With Acute Coronary Syndrome
In patients with chest pain the diagnosis of a heart attack (myocardial infarction) is made where there is evidence of heart muscle damage using a blood test to measure the heart muscle protein troponin.
- Trial name
- High-STEACS (NCT01852123)
- Testing
- High-sensitivity troponin I assay
- Where
- United Kingdom
- Volunteers
- 48,282 people
- Sponsor
- University of Edinburgh
Acute Myocardial Infarction
Hemorrhagic MI Prediction Score Model
Developing a prediction score model for predicting the likelihood of Hemorrhagic MI
- Trial name
- MIRON-PRE-xAI (NCT06423625)
- Where
- United States
- Volunteers
- 252 people
- Sponsor
- Rohan Dharmakumar
Coronary Artery Disease, Myocardial Ischemia
BIOFLOW-III Sweden Satellite Registry
This registry is a clinical post-market evaluation of the Orsiro LESS in subjects requiring coronary revascularization with Drug Eluting Stents (DES).
- Trial name
- NCT01667003
- Where
- 8 sites in Sweden
- Volunteers
- 406 people
- Sponsor
- Biotronik ApS
Heart Failure, Myocardial Infarction
Evaluation of the Safety and Efficacy of Using Insulin-like Growth Factor-1 in Patients With a Heart Attack
When a patient has a heart attack, a blockage occurs in a coronary artery that delivers oxygen to the heart muscle. The heart muscle may weaken, causing heart failure.
- Trial name
- RESUS-AMI (NCT01438086)
- Testing
- mecasermin, 0.9% sodium chloride injection
- Where
- 2 sites in Ireland, Netherlands
- Volunteers
- 47 people
- Sponsor
- University College Cork