Clinical trials: Acute Vestibular Syndrome
Acute Unilateral Vestibular Deafferentiation
Unravelling Risk Factors for Chronic Dizziness in Patients After an Acute Unilateral Vestibular Deafferentiation.
In many patients with an acute unilateral vestibular deafferentiation (uVD) syndrome symptoms are expected to resolve spontaneously because of central compensation.
- Trial name
- Activation (NCT04979598)
- Testing
- Home exercise program
- Where
- Belgium
- Volunteers
- 103 people
- Sponsor
- Universiteit Antwerpen
Vertigo, Peripheral
Non Inferiority of Meclin® (Meclizine Chlorhydrate) Versus Dramin® (Dimenhydrinate) in Control of Acute Vertigo Symptoms From Peripheral Origin
Evaluation of the non inferiority of Meclin (meclizine) versus Dramin (Dimenhydrinate) to treat the symptoms of acute vertigo from peripheral origin after up to 4 weeks of treatment; Evaluation of impact on quality of life in…
- Trial name
- NCT02112578
- Testing
- Meclizine, Dimenhydrinate
- Where
- 7 sites in Brazil
- Volunteers
- 292 people
- Sponsor
- Apsen Farmaceutica S.A.
Diabetic Retinopathy, Macular Degeneration
Advancing Understanding of Transportation Options
This Stage II randomized, controlled, longitudinal trial seeks to assess the acceptability, feasibility, and effects of a driving decision aid use among geriatric patients and providers.
- Conditions
- Diabetic Retinopathy, Macular Degeneration, Glaucoma, Retinitis Pigmentosa
- Trial name
- AUTO (NCT04141891)
- Testing
- Driving Decision Aid, Older Drivers Website
- Where
- 3 sites in United States
- Volunteers
- 529 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Vertigo, Peripheral
Efficacy and Safety of Intravenous Diazepam Given at 2 Different Doses Compared to Placebo in Acute Peripheral Vertigo
This is prospective, randomised double-blind study that will be conducted in the emergency department of 3 university hospitals (FB Monastir, Sahloul Sousse, and FH Sousse) to compare the efficacy of two doses of diazepam…
- Trial name
- Vertigo (NCT06293989)
- Testing
- Diazepam 5mg, Diazepam 10 mg
- Volunteers
- 1,000 people
- Sponsor
- University of Monastir
Stroke, Mild Cognitive Impairment (MCI)
Telerehabilitation Decision Support System: Pilot Testing Protocol
This study follows the successfully completed HOLOBalance project which was funded by the EU Horizon 2020 scheme. TheHOLOBalance platform delivers exercises demonstrated via a hologram of the physiotherapist and corrected in real…
- Conditions
- Stroke, Mild Cognitive Impairment (MCI), Vestibular Disease, Long Covid-19
- Trial name
- TeleRehab DSS (NCT07079787)
- Testing
- TeleRehab DSS Pilot Test
- Where
- 5 sites in Germany, Greece and 3 more
- Volunteers
- 30 people
- Sponsor
- University College, London
Peripheral Vertigo
Sodium Bicarbonate for Acute Peripheral Vertigo
Vertigo is defined as the hallucination of spinning sensation or rotatory movement and is frequently combined with severe nausea and vomiting.
- Trial name
- NCT05676216
- Testing
- Diphenhydramine, Sodium Bicarbonate, Diphenhydramine + Sodium Bicarbonate
- Where
- Taiwan
- Volunteers
- 225 people
- Sponsor
- National Taiwan University Hospital
Acute Vestibular Syndrome, Vertigo
Diagnostic Work up and Management of Acute Onset Vertigo
Incidence: Dizziness or vertigo is a very prevalent complaint in the general population, and a common reason for seeking medical attention.
- Trial name
- NCT05062915
- Testing
- HINTS
- Where
- Denmark
- Volunteers
- 90 people
- Sponsor
- Esbjerg Hospital - University Hospital of Southern Denmark
Stroke, Vertigo
Telemedical Examination of a Three-Component Oculomotor Testing Battery
The study investigates the feasibility and safety of the telemedical implementation of three diagnostic oculomotor tests using a video-oculography device and an extended teleconferencing system.
- Conditions
- Stroke, Vertigo, Dizziness
- Trial name
- NCT02938221
- Testing
- Telemedical video-oculography system
- Where
- Germany
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Munich Municipal Hospital
Ototoxicity
SPI-1005 for Prevention and Treatment of Tobramycin Induced Ototoxicity
The primary objective of this study is to determine the safety and efficacy of SPI-1005 treatment in CF patients with active pulmonary exacerbation that are receiving an IV course of tobramycin, determined by comparing hearing…
- Trial name
- NCT02819856
- Testing
- SPI-1005 Ebselen 200mg Capsule x1, SPI-1005 Ebselen 200mg Capsule x2, SPI-1005 Ebselen 200mg Capsule x3
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- Sound Pharmaceuticals, Incorporated
Acute Vestibular Syndrome
Web-based Rehab After Acute Vertigo
Acute onset vertigo is common and entails much suffering with persisting symptoms at 3 months after onset in up to half of those afflicted. Vestibular rehabilitation to aid recovery is not readily available.
- Trial name
- NCT05056324
- Testing
- Online vestibular rehabilitation tool, Standard care (written instructions leaflet)
- Where
- 9 sites in Sweden
- Volunteers
- 184 people
- Sponsor
- Umeå University
Acute Vestibular Syndrome, Emergencies
Eye-ECG Approach to Emergencies : Diagnostic Performance of the HINTS Test
Vertigo integrated with acute vestibular syndrome (AVS) is a frequent reason for emergency visits. The French and international literature estimates between 2 to 4% of vertigo prevalence among reasons for coming to emergencies.
- Trial name
- NCT04118361
- Testing
- HINTS Test, STANDING Algorithm
- Where
- France
- Volunteers
- 300 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Shortness of Breath, Chest Pain
Checklists Resuscitation Emergency Department
The study will systematically evaluate how an emergency manual-a collection of checklists and fact sheets-affects the performance of resuscitation teams during the management of priority one patients in an emergency department.
- Conditions
- Shortness of Breath, Chest Pain, Abdominal Pain, Altered Mental Status
- Trial name
- NCT05649891
- Testing
- Emergency Manual
- Volunteers
- 2,000 people
- Sponsor
- Region Skane
Acute Vestibular Syndrome, Vertigo
Quantitative Eye Movement Measurements in Patients with Acute Vestibular Syndrome
BACKGROUND: A chief complaint of acute vertigo/dizziness is related to about 2.1-7.1% of all emergency department (ED) visits. About 25% of all patients with acute prolonged vertigo meeting diagnostic criteria of AVS (acute…
- Conditions
- Acute Vestibular Syndrome, Vertigo, Stroke Acute, Acute Unilateral Vestibulopathy (AUV)
- Trial name
- NCT06668857
- Testing
- video-oculography
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Alexander Tarnutzer
Vertigo, Dizziness
Acute Video-oculography for Vertigo in Emergency Rooms for Rapid Triage (AVERT)
AVERT is a randomized controlled trial comparing video-oculography (VOG)-guided care to standard care to assess accuracy of diagnoses and initial management decisions for emergency department (ED) patients with a chief symptom of…
- Trial name
- AVERT (NCT02483429)
- Testing
- VRT Care
- Where
- 5 sites in United States
- Volunteers
- 130 people
- Sponsor
- Johns Hopkins University
Acute Vestibular Syndrome, Emergencies
Accuracy and rEliabilitY of the vEstibuLo-ocular ExAmination Performed by inteRNs IN the emerGency Department
Dizziness, loss of balance, and unsteadiness of gait are common symptoms reported by Emergency Department (ED) patients. The incidence of acute vestibular syndrome (AVS) is increasing and reaches 2-4% of ED visits.
- Trial name
- EYE LEARNING (NCT04919187)
- Where
- France
- Volunteers
- 321 people
- Sponsor
- Fondation Hôpital Saint-Joseph
Vestibular Vertigo
AM-125 in the Treatment of Acute Peripheral Vertigo Following Neurosurgery
Treatment of vertigo after removal of a tumor of the balance and hearing nerve after neurosurgery, which damages or cuts the vestibular nerve (balance).
- Trial name
- TRAVERS (NCT03908567)
- Testing
- Intranasal Drug, Oral Tablet
- Where
- France
- Volunteers
- 124 people
- Sponsor
- Auris Medical AG
Stroke, Mild Cognitive Impairment
Telerehabilitation of Balance Clinical and Economic Decision Support System
This study follows the successfully completed HOLOBalance project which was funded by the EU Horizon 2020 scheme. TheHOLOBalance platform delivers exercises demonstrated via a hologram of the physiotherapist and corrected in real…
- Conditions
- Stroke, Mild Cognitive Impairment, Vestibular Diseases, Long Covid19
- Trial name
- TeleRehab DSS (NCT06534164)
- Testing
- Full/High Tech Telerehabilitation decision support system, Basic/Low Tech Telerehabilitation decision support system, OTAGO Home exercise program
- Where
- 5 sites in Germany, Greece and 3 more
- Volunteers
- 460 people
- Sponsor
- University College, London
Stroke, Acute, Vertigo
vHIT Testing for Presentation of Dizziness at a Comprehensive Stroke Center
The purpose of this study is to evaluate the sensitivity and specificity of the video head impulse test (vHIT) device, when implemented in the acute ED setting to identify acute ischemic stroke or central pathology vs peripheral…
- Conditions
- Stroke, Acute, Vertigo, Vertigo, Peripheral, Dizziness
- Trial name
- NCT06038175
- Testing
- Video Head Impulse Testing, Standard of care neurologic evaluation
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Medical University of South Carolina
Dizziness, Nausea
Effect of Vestibular Rehabilitation - a Randomized Controlled Trial
The aim of this study is to assess if early supported vestibular rehabilitation can reduce dizziness and improve daily life activities in patients with acute vestibular injury.
- Conditions
- Dizziness, Nausea, Nystagmus, Vestibular Diseases
- Trial name
- NCT00702832
- Testing
- Vestibular rehabilitation, standard treatment
- Where
- Norway
- Volunteers
- 54 people
- Sponsor
- Norwegian University of Science and Technology
Vestibular Diseases, Vestibular Neuronitis
Acute Unilateral Vestibulopathy and Corticosteroid Treatment
Randomized placebo controlled trial on patients suffering from acute unilateral vestibulopathy. Patients will be randomized into 3 arms; 1) Placebo only, 2) Short corticosteroid treatment (3days) 3) Longer corticosteroid…
- Trial name
- NCT02912182
- Testing
- Betamethasone, Prednisolone
- Where
- 3 sites in Sweden
- Volunteers
- 78 people
- Sponsor
- Lund University