Clinical trials: Adaptation
Performance, Nutrition
Nutrient Supplementation Influences Mitochondria Adaptation
Twenty-four well trained runners (VO2max 60.73.7 ml O2 Kg-1 min1) completed a six week block randomized controlled intervention period.
- Conditions
- Performance, Nutrition, Protein
- Trial name
- NCT03561337
- Testing
- PROTEIN-CARBOHYDRATE, CARBOHDYRATE
- Where
- 2 sites in Denmark
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
Stress, Well-being
Mindfulness for Stress and Well-being in University Students
In developing countries such as Pakistan, the challenges university students face are many-fold and there is a need for an intervention that helps build students' connection with themselves, utilizing their internal resources to…
- Trial name
- NCT05216445
- Testing
- Mindfulness Training
- Where
- Pakistan
- Volunteers
- 157 people, healthy volunteers welcome
- Sponsor
- National University of Science and Technology, Pakistan
Aging, Cardiovascular Disease
CALERIE (PBRC, Baton Rouge) - Comprehensive Assessment of Long-Term Effects of Reducing Intake of Energy
This study is one of three CALERIE trials that test the hypothesis that a reduced calorie, nutritionally sound diet improves biomarkers of aging and prevents some age-related chronic diseases such as cancer, diabetes, and…
- Conditions
- Aging, Cardiovascular Disease, Diabetes Mellitus
- Trial name
- NCT00099151
- Testing
- Caloric Restriction (CR), Exercise
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- National Institute on Aging (NIA)
High-altitude Training Adaptations in Adolescent Male Rowers
Effects of a 4-Week Altitude Training on Sport-Specific Performance, Body Composition, and Cardiac and Pulmonary Function in Adolescent Male Rowers
This study aims to investigate the effects of a 4-week altitude training program on adolescent male rowers. The research will examine changes in athletic performance, athletic body composition, athletic cardiac function, athletic…
- Trial name
- NCT07612956
- Testing
- 4-Week Altitude Training
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Macao Polytechnic University
Myotonic Dystrophy 1
Home-based Training and Supplementation in DM1 Patients
Myotonic dystrophy type 1 (DM1) is a rare genetic disease that affects about 1 in 2100 people. Patients diagnosed with DM1 present with many symptoms, however, their muscles are mainly affected.
- Trial name
- DM1HBET (NCT05848830)
- Testing
- Mult-ingredient supplement, Concurrent exercise training
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- McMaster University
Incomplete Spinal Cord Injury
The Effect of Acute Intermittent Hypoxia on Motor Learning
The goal of this study is to examine the effect of repetitive acute intermittent hypoxia on motor learning abilities in able-bodied individuals for subsequent study in individuals with incomplete spinal cord injury.
- Trial name
- NCT05341466
- Testing
- Acute Intermittent Hypoxia
- Where
- 2 sites in United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Prediabetic State
Autoimmune Diabetes Accelerator Prevention Trial
The autoimmune diabetes ACCELERATOR PREVENTION TRIAL (adAPT) is based on the accelerator hypothesis. The trial is designed to establish whether metformin, an oral hypoglycaemic agent that is known to reduce insulin demand in type…
- Trial name
- adAPT (NCT02881528)
- Testing
- Metformin Hydrochloride
- Where
- 5 sites in United Kingdom
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Exeter
Umbilical Cord Clamping
30-Second Versus Pulsation-Based Delayed Cord Clamping in Term Newborns
This randomized controlled trial aims to compare the effects of 30-second cord clamping and pulsation-based delayed cord clamping on neonatal metabolic adaptation in term newborns delivered vaginally.
- Trial name
- NCT07833059
- Testing
- Pulsation-Based Delayed Cord Clamping, 30-Second Cord Clamping
- Where
- Turkey (Türkiye)
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Tarsus University
Memory, Learning
Cognitive, Emotional, Physical and Psychosocial Effects of Panax Quinquefolius L
The purpose of this study is to determine the efficacy and safety of REMEMBER-fX (HT1001, an extract of Panax quinquefolius) in a human sample using standard clinical neuropsychological instruments and side effects rating scales.
- Conditions
- Memory, Learning, Attention, Cognition
- Trial name
- REMEMBER-fX (NCT00527969)
- Testing
- HT1001 extract of Panax quinquefolius L
- Where
- Canada
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- CV Technologies
Quality of Life, Breast Cancer
Program of Physical Activity, Nutrition and Supportive to Improve the Quality of Life of Breast Cancer Survivors
Despite it being one of the leading causes of cancer death among women, survival following a breast cancer diagnosis has greatly increased in high-income countries.
- Trial name
- ADA (NCT05658341)
- Testing
- ADA, Usual Care
- Where
- 8 sites in France
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Siel Bleu
Heart Diseases
Cross Cultural Adaptation of International Physical Activity Questionaire Short Form in Urdu Version
The IPAQ-SF scale is widely used in our clinical settings. The translated version of IPAQ-SF scale in Urdu will help the clinician in collecting data thus, easy to understand for the patient and making it more desirable in our…
- Trial name
- NCT04973865
- Testing
- Validation & reliability
- Where
- Pakistan
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Riphah International University
High-risk Pregnancy, Breast Feeding
Effect of Hypnobreastfeeding Education in High-Risk Pregnant Women
It is thought that hypnobreastfeeding training given to high-risk pregnant women will reduce anxiety levels, increase lactation, encourage breastfeeding, reduce the perception of insufficient milk, and facilitate adaptation to…
- Trial name
- NCT07281339
- Testing
- Hypnobreastfeeding Education
- Where
- Turkey (Türkiye)
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- Amasya University
Maternal Nutrition, Child Nutrition
Climate-Responsive Nutrition, WASH, and Heat Counselling for Maternal and Child Health in Sindh, Pakistan
The goal of this trial is to evaluate whether a climate- and gender-responsive integrated package of nutrition, hygiene (WASH), and heat-adaptation counselling can improve maternal and child health and nutrition outcomes among…
- Trial name
- IGNIT3 (NCT07819994)
- Testing
- Training of Lady Health Workers (LHWs), Training of Healthcare Providers (HCPs) at Facilities
- Where
- Pakistan
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- The Hospital for Sick Children
Hearing Impairment, Sensorineural Hearing Loss, Bilateral
Hearing Aid Noise Reduction in Pediatric Users Pilot Study (Oticon Pilot Study)
The purpose of this study is to evaluate the efficacy of OpenSound Navigator (OSN), a hearing aid speech-enhancement algorithm developed by Oticon, as treatment for pediatric hearing aid users.
- Trial name
- NCT04469946
- Testing
- Oticon OpenSound Navigator speech enhancement algorithm
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Neuropsychological Tests, Memory
Adaptation and Normalization of a Verbal Episodic Memory Test in French Sign Language
To date, neuropsychological assessment of deaf signing persons is complicated by a lack of resources, especially the absence of tools available in French Sign Language (LSF).
- Conditions
- Neuropsychological Tests, Memory, Alzheimer Disease, Deafness
- Trial name
- RL-RI-LSF (NCT06902753)
- Testing
- Questionnaire and Physical Exam
- Where
- France
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Poitiers University Hospital
Pharmacokinetics
Product Use and Adaptation, Safety and Tolerability of P3P in Adult Healthy Smokers Switching to it
The purpose of the study is to evaluate the product use and adaptation in adult, current cigarette smoking subjects between baseline and after one month of use of one of two P3P variants.
- Trial name
- NCT03953183
- Testing
- P3P-1mg, P3P-2mg
- Where
- Russia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Philip Morris Products S.A.
No Disease
A Study to Test the Repeatability and Reproducibility in Rod Intercept Time Within the AdaptDx Pro in Healthy Subjects With Normal Vision (FlashForward)
The purpose of this study is to test the repeatability and reproducibility in Rod Intercept (RI) time with two AdaptDx Pro devices in healthy subjects with normal vision.
- Trial name
- FlashForward (NCT07860905)
- Testing
- AdaptDx Pro
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- AdaptDx, Inc.
Autism Spectrum Disorder, Motor Disorders
Evaluation of Motor Skills, Balance, Dual Task, and Social Adaptation in Individuals with Autism
The aim of our study is to evaluate motor skills balance, dual task and social adaptation skills in individuals with autism. Our study will be conducted in Bartın Lider Special Education and Rehabilitation Center after ethics…
- Conditions
- Autism Spectrum Disorder, Motor Disorders, Social Skills
- Trial name
- NCT06777186
- Testing
- 10 meter walk test, Functional Balance, Social Adaptation Assessment
- Where
- Turkey (Türkiye)
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Kırıkkale University
Healthy, Healthy Participants
Acute Effects of Structured Exercise and Static Stretching on Vascular Function, Neuromuscular Performance, and Metabolic Regulation in Adults
This experimental study investigates the acute cardiovascular and vascular responses to a single session of resistance training, with and without additional static stretching, compared with a resting control condition.
- Conditions
- Healthy, Healthy Participants, Healthy Subjects (HS), Resistance Training Adaptation
- Trial name
- NCT07364149
- Testing
- Resistance Training, Resistance training + Static Stretching
- Where
- Italy
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Palermo
Healthy, Healthy Subjects (HS)
Static Stretching Reshapes Post-RT Recovery
This experimental study investigates the acute cardiovascular and local recovery to a single session of resistance training, with and without additional static stretching, compared with a resting control condition.
- Conditions
- Healthy, Healthy Subjects (HS), Cardiovascular Adaption, Stretching
- Trial name
- NCT07649785
- Testing
- Resistance Training, Resistance training + Static Stretching
- Where
- Italy
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Palermo
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