Clinical trials: Addiction Disorders
Osteoarthritis, Knee, Self Stimulation
Exercise and Muscle Stimulation in Patients With Knee Osteoarthritis
Objective: To evaluate the effectiveness of neuromuscular electrical stimulation (NMES) combined with closed kinetic chain (CKC) exercises in patients with knee OA.
- Conditions
- Osteoarthritis, Knee, Self Stimulation, Exercise Addiction
- Trial name
- NCT01320904
- Testing
- NMES, Closed Kinetic Chain
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- Universidade Luterana do Brasil
Smoking Cessation, Tobacco Use Disorder
Effectiveness of Reducing Smoking in Facilitating Smoking Cessation in Adolescents - 2
Currently one in five high school students smoke. Smoking can harm adolescents well before they reach adulthood by causing a number of immediate, sometimes irreversible, health risks and problems.
- Trial name
- NCT00158158
- Testing
- Usual Care, Smoking Reduction
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Institute on Drug Abuse (NIDA)
Alcohol Related Disorders, Substance Related Disorders
The Co-Venture Trial: A Cluster Randomized Trial of Personality-targeted Interventions on Adolescent Substance Use and Cognitive Outcomes
The Preventure Program is the first and only school-based alcohol and drug prevention program that has been shown to prevent onset and growth in alcohol and substance misuse in British and Canadian youth.
- Trial name
- NCT01655615
- Testing
- Preventure programme
- Where
- Canada
- Volunteers
- 3,900 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Internet Addiction
WeChat-based Intervention for Internet Addiction
The study aims to design an integrated model which combined self-initiated online learning and personalized interactive behavioral support delivered via WeChat for university students to reduce internet addiction level.
- Trial name
- NCT05906108
- Testing
- Self-initiated learning, Personalized and interactive behavioural support, General health information
- Where
- Hong Kong
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Prof. Wang Man-Ping
Social Media Addiction
4-STEP Training Program for Social Media Addiction, Cognitive Fatigue, Psychological Distress, Academic Burnout and Procrastination Among Students
This study aims to evaluate the effectiveness of a structured four-step training program for reducing social media addiction and its associated psychological and academic difficulties among school and university students.
- Trial name
- 4-STEP-TPS (NCT07821489)
- Testing
- 4-STEP-TPS
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Government College University Faisalabad
Drug Addiction, Executive Dysfunction
Bilateral Prefrontal Modulation in Alcoholism
In this study, eligible alcoholic inpatients recruited from a specialized clinic for addiction treatment, filling inclusion criteria and not showing any exclusion criteria, were randomized to receive the repetitive (10 sessions…
- Trial name
- tDCS_ALCOHOL (NCT02091284)
- Testing
- transcranial Direct Current Stimulation
- Where
- Brazil
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Federal University of Espirito Santo
Problematic Smartphone Use, Perceived Stress
The Effect of Mindfulness-Based Stress Reduction Programme on Smartphone Addiction, Stress and Quality of Life in University Students
This study examined whether a brief mindfulness-based stress reduction program could help university students reduce problematic smartphone use and perceived stress and improve their quality of life.
- Conditions
- Problematic Smartphone Use, Perceived Stress, Health-Related Quality of Life
- Trial name
- Mindfulness (NCT06819540)
- Testing
- Brief Mindfulness-Based Stress Reduction (MBSR) Program
- Where
- Turkey (Türkiye)
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Hasan Kalyoncu University
Type 2 Diabetes
Processed Meat and Brain Regions Related to Reward and Addiction
The purpose of this study is to 1. Compare effects of two isocaloric meals (processed meat hamburger vs. vegetarian sandwich) in response to the postprandial period by using functional brain imaging of reward circuitry implicated…
- Trial name
- RewCrav (NCT02474147)
- Testing
- Processed meat hamburger, Vegan sandwich
- Where
- Czechia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Institute for Clinical and Experimental Medicine
Opiate Addiction
Buprenorphine and Methadone for Opioid Dependent Chronic Pain Patients
The purpose of this study is to determine if buprenorphine or methadone is better for the treatment of chronic pain among patients who have become addicted to prescription narcotics.
- Trial name
- NCT00879996
- Testing
- Methadone, Buprenorphine/naloxone
- Where
- 2 sites in United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- State University of New York at Buffalo
Internet Addiction Disorder, Health Promotion
The Effect of Health Education on Digital Game Addiction and Health Promotion Behavior in Adolescents
This study aimed to evaluate the effectiveness of a school nurse-led health education program in reducing digital game addiction and improving health-promoting behaviors among adolescents.
- Conditions
- Internet Addiction Disorder, Health Promotion, Digital Game Addiction, Adolescent
- Trial name
- NCT07002515
- Testing
- Health Education Program
- Where
- Turkey (Türkiye)
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi Gulhane Tip Fakultesi
Alcohol Use Disorder
Does Oxytocin Alter Tolerance to or Motivation for Alcohol
This pilot study is intended to demonstrate feasibility and acquire preliminary data. If successful, this data could support a future project studying the effect of oxytocin on tolerance and alcohol seeking in humans.
- Trial name
- NCT05312008
- Testing
- Intranasal oxytocin
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Indiana University
Nicotine Dependence, Nicotine Addiction
A Smartphone Application (ACT on Vaping) for Vaping Cessation in Young Adults
Almost one in ten young adults report current e-cigarette use, putting them at risk of developing nicotine addiction and long-term health effects of exposure to inhaled toxicants.
- Conditions
- Nicotine Dependence, Nicotine Addiction, Nicotine Use Disorder, Nicotine Vaping
- Trial name
- NCT05897242
- Testing
- Smartphone app, Text Message, Survey Administration
- Where
- United States
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Fred Hutchinson Cancer Center
Risk Behavior, Social Media Addiction
Effect of Solution-Focused Approach on the Internet,Social Media Addiction and Self-Efficacy Levels OfNursing Students
The purpose of this research; is to determine the effect of solution-oriented approach on internet, social media addiction and self-efficacy levels of nursing students.
- Conditions
- Risk Behavior, Social Media Addiction, Internet Addiction
- Trial name
- NCT06674746
- Testing
- SOLUTION FOCUSED APPROACH
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cumhuriyet University
Internet Gaming Disorder, Social Media Addiction
Chatbot Intervention to Reduce Common Digital Addictions, Sedentary Behaviors and Mental Distress Among Adolescents
The goal of the study is to investigate the efficacy of a secondary low-intensity stage of change (SoC) and motivational interviewing (MI)-based Chatbot-assisted intervention in reducing digital addictions in adolescents with…
- Trial name
- NCT06821373
- Testing
- Chatbot, Control
- Where
- Hong Kong
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
PTSD, Addiction
The Course and Outcome of Integreated Trauma and Addiction Treatment Between PTSD and CPTSD
In the ICD-11 post-traumatic stress disorder (PTSD) and complex PTSD (CPTSD) are distinguished. CPTSD is associated with early childhood traumatization and more severe symptom patterns.
- Trial name
- NCT06588309
- Testing
- Eye movement desensitization and reprocessing (EMDR), CRA
- Where
- Netherlands
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- IrisZorg
E-cigarette Use/Vaping Prevention, Nicotine Dependence Prevention
A Virtual Reality E-cigarette Prevention and Emotion Regulation Intervention for Adolescents
This study will examine E-Invite Only VR, a novel school-based universal e-cigarette prevention intervention that uses virtual reality (VR) to deliver prevention and emotion regulation skills-building content to middle school…
- Conditions
- E-cigarette Use/Vaping Prevention, Nicotine Dependence Prevention, Adolescent Mental Health
- Trial name
- NCT07460622
- Testing
- Virtual Reality E-Cigarette Prevention Program
- Where
- United States
- Volunteers
- 1,251 people, healthy volunteers welcome
- Sponsor
- Yale University
Substance Use Disorders
Contingency Management Using Smartphone App in Patients With SUD
The purpose of this research study is to test the acceptance and efficacy of a smartphone app (DynamiCare Rewards) for patients with substance use disorder (SUD) who are in active treatment and recovery at BrightView.
- Trial name
- NCT04162132
- Testing
- Smartphone app
- Where
- United States
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- BrightView LLC
Nicotine Dependence
Cue Induced Imaging in Nicotine Dependent Smokers
The purpose of this study is to evaluate the relationship between craving to smoke and areas activated in brain. The researchers are using functional magnetic resonance imaging (MRI) that measures brain blood flow, or perfusion…
- Trial name
- NCT00844701
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Medical University of South Carolina
Food Addiction, Sexual Addiction
Physiopathology of Behavioral Addictions and Biomarkers
The goal of this observational study is to evaluate the expression of miR-10a-5p in the blood in patients with sexual addiction or food addiction.
- Trial name
- MiRACle (NCT07830680)
- Testing
- blood sampling
- Where
- France
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Nantes University Hospital
Caregiver Burden
Evaluating a Peer-Facilitated Skills-Based Intervention for Caregivers of Concurrent Disordered Youth
Families of adolescents struggling with comorbid mental illness and addiction problems typically experience considerable emotional, financial and social burdens.
- Trial name
- NCT02243761
- Testing
- DBT Based Skills Groups for Families
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre for Addiction and Mental Health