Clinical trials: Advanced Age
Mild Cognitive Impairment, Mild Dementia
Validation of the German Version of the Amsterdam Instrumental Activities of Daily Living Questionnaire®
Pretest and validation of the German version of the Amsterdam instrumental activities of daily living questionaire short in elderly people with normal cognition, mild cognitive impairment (MCI) or mild dementia in the German…
- Trial name
- NCT04012398
- Testing
- Amsterdam IADL Questionnaire short, German version
- Where
- Switzerland
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Zurich University of Applied Sciences
Alzheimer Disease, Mild Dementia
Acute Effect of Low-intensity Gamma rTMS on Cognitive and EEG Parameters in Adults With Mild Dementia by Alzheimer's Disease
Neurocognitive disorders have a growing prevalence and impact on public health; their main etiology corresponds to Alzheimer's disease. To date, there is no treatment that can reverse neuronal damage in these pathologies.
- Trial name
- NCT05784298
- Testing
- low-intensity rTMS
- Where
- Mexico
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran
Cognitive Aging
Guanfacine Treatment for Prefrontal Cognitive Dysfunction in Elderly Subjects
This proposal aims to determine whether low does of the alpha-2A-adrenoceptor agonist guanfacine can improve deficits in prefrontally-mediated cognitive functions in healthy elderly subjects.
- Trial name
- NCT00935493
- Testing
- Guanfacine
- Where
- United States
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Yale University
Parkinson's Disease
Visual Function During Gait in Parkinson's Disease: Impact of Cognition and Response to Visual Cues
Parkinson's disease (PD) is associated with problems of gait such as veering, difficulty turning, an inability to perceive doorways or obstacles, and negotiate uneven terrain.
- Trial name
- NCT02610634
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Newcastle-upon-Tyne Hospitals NHS Trust
Subjective Cognitive Decline
LLM-Driven Daily Conversation for Cognitive Health in Older Adults
This study will develop and test a daily conversation platform that uses a large language model, a type of artificial intelligence, to support cognitive health in older adults at high risk of dementia.
- Trial name
- LLM-DCI (NCT07751510)
- Testing
- LLM Conversation Cognitive Interaction, Interest-Based Knowledge Reading, Waitlist Health Education
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Taipei Medical University Shuang Ho Hospital
Influenza Vaccination
Family Physician Nudges for Influenza Vaccination Among Older Adults
The goal of this clinical trial is to learn if a family-physician nudge intervention works to improve influenza vaccination among adults aged 65 years and older in China.
- Trial name
- NCT07864597
- Testing
- Family Physician Influenza Vaccination Nudge
- Volunteers
- 3,060 people, healthy volunteers welcome
- Sponsor
- Fudan University
Tuberculosis, Pulmonary
ID93+GLA-SE Vaccine Against Tuberculosis in Older Adults Aged 55-74
The purpose of this study is to evaluate the safety and explore the immunogenicity of ID93+GLA-SE compared to placebo following three intramuscular (IM) injections on Days 0, 28 and 56 in the Bacillus Calmette-Guérin…
- Trial name
- NCT06714513
- Testing
- QTP101
- Where
- 4 sites in South Korea
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Quratis Inc.
Dietary Intervention, Dietary Proteins
Investigating the Cognitive and Brain Health Benefits of Lean Pork Consumption
The goal of this clinical trial is to learn if eating more lean pork will lead to better cognition and a healthier brain in older adults.
- Conditions
- Dietary Intervention, Dietary Proteins, Dietary Assessment, Older Adults (65 Years and Older)
- Trial name
- NCT07031076
- Testing
- Ready-to-eat lean pork in frozen, 5-oz packages
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Nebraska Lincoln
Cardiovascular Diseases, Diabetes Mellitus
A Community Paramedicine Initiative for Older Adults Living in Subsidized Housing (CHAP-EMS/CP@Clinic)
Older adults living in subsidized housing report poorer health. Their age and low income make it harder for them to use community services.
- Trial name
- CHAP-EMS (NCT02152891)
- Testing
- CHAP-EMS/CP@clinic
- Where
- 5 sites in Canada
- Volunteers
- 1,200 people, healthy volunteers welcome
- Sponsor
- McMaster University
Locomotor Activity, Functionally-Impaired Elderly
Reliability and Validity of the Elderly Mobility Scale, French Version
This study evaluates the reliability of the French version of the "elderly mobility scale" and its correlation with the "frailty elderly scale "
- Conditions
- Locomotor Activity, Functionally-Impaired Elderly, Frail Elderly
- Trial name
- NCT03008135
- Testing
- Elderly Mobility Scale, Frailty scale
- Where
- 3 sites in France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Pole Santé Plouasne Saint Pern Becherel
Oral Hygiene, Oral Health, Dental Plaque
Essential Oil Mouthwash - Oral Hygiene
Background Inadequate oral health can further compromise general health, particularly in elderly patients who are more susceptible to tooth loss, periodontal disease, and oral infections.
- Conditions
- Oral Hygiene, Oral Health, Dental Plaque, Respiratory Tract Infections (RTI)
- Trial name
- EOMOH-RCT (NCT07887074)
- Testing
- Essential oil mouthwash, Chlorhexidine gluconate alcohol-free mouthwash, Povidone-iodine alcohol-free mouthwash
- Where
- Taiwan
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- China Medical University, Taiwan
Memory Impairment
Memory and Exercise Training Study in Older Adults With Subjective Memory Complaints
This pilot study is a first step in a rapidly growing area of clinical research to create the most effective means to combat age-related losses in cognitive function through preventive lifestyle strategies such as physical…
- Trial name
- MET (NCT02433691)
- Testing
- simultaneous aerobic exercise, sequential aerobic exercise, stretching and toning
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- David Merrill, MD, PhD
Healthy Aging
The Effects of Different Intensity Training on Strength and Mobility of Elderly
In this study, investigators tried to find a useful and safe way of training for the elderly population which can help this population to improve their fitness factors as fast as possible.
- Trial name
- NCT04892836
- Testing
- Training
- Where
- Malaysia
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Universiti Putra Malaysia
Cognitive Decline
Cognitive Training and Social Interaction Effects on Cognitive Performance of Older Adults
Aging is associated with a decline in almost all aspects of cognitive functions, particularly memory. Recent research suggests that combining cognitive training with ongoing social interaction may aid in improving cognitive…
- Trial name
- NCT05016336
- Testing
- Social interaction combined with cognitive training based on mnemonic strategies., Social interaction group
- Where
- Israel
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Bar-Ilan University, Israel
Malnutrition, Intestinal Integrity
Changes in Circulatory I-FABP in Elderly Persons in Daily Life
The purpose of this study is to detect changes in circulatory I-FABP values (50% increase) in elderly volunteers following the combination of moderate physical activity and a standard meal.
- Conditions
- Malnutrition, Intestinal Integrity, Intestinal Fatty Acid Binding Protein (IFABP)
- Trial name
- NCT02831400
- Testing
- Walking test, Standard Meal
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University Medical Center Groningen
Fall, Aging
Study of Static and Dynamic Posturographic Elements Predictive of Falls in the Institutionalized Elderly
A fall in the elderly is defined by the WHO as "an event in which a person [over 65 years of age] inadvertently falls to a lower level on the ground or other surface than they were previously at".
- Conditions
- Fall, Aging, Gait, Unsteady, Motor Activity
- Trial name
- POSTADYCHUTE (NCT05171036)
- Testing
- Adapted Physical Activity
- Volunteers
- 348 people, healthy volunteers welcome
- Sponsor
- Centre Borelli UMR 9010
Diabetes, Obesity
The Effect of Dairy and Non-dairy Breakfasts on Satiety and Post-meal Glycemia in Healthy Older Adults
This study investigates the effects of dairy breakfasts (2% cow's milk, 2% Greek yogurt, cheese) and a non-dairy breakfast (soy beverage) on satiety and post-meal blood glucose.
- Trial name
- NCT02607007
- Testing
- 2% M.F. Milk, White Bread, Strawberry Jam
- Where
- Canada
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Fall Risk in Middle-Aged and Older Adults
Short-term Changes in Postural Sway, Gait, and fNIRS-derived Cortical Metrics After a 4-week AI-assisted Exercise Program: a Single-arm Pre-post Study
This single-arm pre-post study will enroll 50 participants aged 52-65 years who will undergo a 4-week AI-assisted exercise intervention.
- Trial name
- NCT07876011
- Testing
- AI-assited exercise
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Peking University Third Hospital
Nocturia
VA106483 Dose Response Study in Elderly Males
The main purpose of the study is to evaluate the way VA106483 enters and leaves the blood and tissues over time and how the drug acts on and in the body at various dose levels compared to placebo in the same volunteer.
- Trial name
- NCT00922740
- Testing
- VA106483
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Vantia Ltd
Well Aging
Active Body and Mind Intervention for Older Adults
This study aimed to examine the effectiveness and acceptability of wearable activity trackers with self-regulatory techniques for promoting physical activity (PA) in older adults.
- Trial name
- NCT05233813
- Testing
- Active Body and Mind
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- University of Michigan
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