Clinical trials: Advanced Age
Falls, Falls Injury
EXpress Prevent Rural oldEr Adults' fallS, fractureS and Dependency (EXPRESS)
Falls are the leading cause of injury-related death among individuals aged 65 and above in China. The incidence of falls shows a significant urban-rural disparity in China, with rural areas experiencing a markedly higher rate…
- Conditions
- Falls, Falls Injury, Fall Prevention
- Trial name
- EXPRESS (NCT06984978)
- Testing
- AI-assisted, village doctors and express services-involved personalized fall prevention strategy
- Where
- China
- Volunteers
- 1,881 people, healthy volunteers welcome
- Sponsor
- Peking University
Healthy
Single Increasing Doses of BIII 890 CL in Healthy Young Male Volunteers and in Healthy Elderly Male and Female Volunteers
Safety, tolerability and pharmacokinetics of BIII 890
- Trial name
- NCT02269215
- Testing
- BIII 890 CL
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Cognitive Decline
Comparison of Three Motor-cognitive Training Programs
Understanding how to delay age-related physical and mental declines is an issue for aging research. It has been shown that isolated aerobic, coordination and cognitive training improve brain functions and cognitive performances.
- Trial name
- EXECO (NCT04504643)
- Testing
- Technology-assisted circuit training, Conventional circuit training, Nordic walking
- Where
- France
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Aix Marseille Université
Polypharmacy (Individuals Treated With 4 or More Medications)
THE EFFECTS OF MULTIPLE DRUG USE ON BALANCE, FALL RISK, AND COGNITIVE STATUS
This study aims to evaluate the effects of polypharmacy on balance, fall risk, cognitive status, vestibular function, and hearing among individuals living in nursing homes.
- Trial name
- NCT07816276
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Aging, Mitochondrial Dysfunction
A Single and Multiple Dose Study of AMAZ-02 to Evaluate Safety and Pharmacokinetics in Elderly Subjects
Part A: The study is a double-blind, randomized, single ascending doses, study in 24 healthy elderly male and female volunteers. Each subject will be randomized for two subsequent doses in three cohorts.
- Conditions
- Aging, Mitochondrial Dysfunction, Muscle Function
- Trial name
- NCT02655393
- Testing
- Mitopure
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Amazentis SA
Atrophy, Muscular
A Clinical Study to Assess the Safety, Tolerability and Pharmacokinetics of Oral SRT2104 Capsules Administered to Healthy Elderly Subjects for 28 Days
The primary objective is to determine the pharmacokinetics, safety and tolerability of SRT2104 in healthy elderly subjects following single and 28 days dosing. The secondary objectives of the study are: 1.
- Trial name
- NCT00964340
- Testing
- SRT2104
- Where
- United Kingdom
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Delirium
Preventative Delirium Protocol in Elderly Patients
The current study aims to elucidate the effectiveness of a preventative delirium protocol in patients older than 65 years of age undergoing elective surgery.
- Trial name
- NCT03541408
- Testing
- Control, Preventative Delirium Protocol
- Where
- United States
- Volunteers
- 263 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
COVID-19
Safety and Immunogenicity Study of Inactivated Vaccine for Prevention of SARS-CoV-2 Infection(COVID-19)
This study is a randomized, double-blinded, and placebo controlled phase 1\&2 clinical trial of the SARS-CoV-2 inactivated vaccine manufactured by Sinovac Life Sciences Co. , Ltd.
- Trial name
- NCT04383574
- Testing
- Two doses of medium dosage inactivated SARS-CoV-2 vaccine at the schedule of day 0,28, Two doses of high dosage inactivated SARS-CoV-2 vaccine at the schedule of day 0,28, Two doses of low dosage inactivated SARS-CoV-2 vaccine at the schedule of day 0,28
- Where
- China
- Volunteers
- 422 people, healthy volunteers welcome
- Sponsor
- Sinovac Life Sciences Co., Ltd.
Healthy
Fermented Papaya and Driving Simulator Older Adult Study
Yes, this additional detail will refine the original template content to emphasize the study's specific aims and hypotheses. Here's an updated version: The goal of this clinical trial is to assess if Fermented Papaya Preparation…
- Trial name
- FPP (NCT06672874)
- Testing
- Fermented Papaya Preparation (FPP)
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Florida
Older Adults
The Effects of Texture Modified Diets on Dietary Intake and Appetite Responses in Older Adults
This study aims to investigate the effects of equicaloric texture modified and regular meals that are either fortified with protein or not on dietary intake and satiety in older adults (65+) living in the United Kingdom (UK).
- Trial name
- NCT04521374
- Testing
- Preload meals that are solid or texture modified and are fortified with protein or not fortified with protein
- Where
- United Kingdom
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- University of Reading
Sedentary Lifestyle
A Smartphone App to Improve Physical Activity
The purpose of this study is to develop, test, and optimize a physical activity (PA)-tracking smartphone app and specialty features, which are designed to facilitate older adults' PA by targeting common barriers in this…
- Trial name
- NCT03417440
- Testing
- Physical Activity (PA) Tracker App, On Your Feet, Coach Me
- Where
- 2 sites in United States
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- University of Southern California
Inappropriate Prescribing
Using a Mobile Application as a Support at the Prescription of Appropriate Medications for Elderly
Objective: To develop and evaluate the effectiveness of a mobile application to support decision making for prescription drugs to elderly patients.
- Trial name
- NCT02918643
- Testing
- Use of an application to for mobile devices like decision-making support for prescription drugs to elderly patients
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Federal University of Bahia
Cognitive Impairment
Preoperative Cognitive Screening of Elderly Surgical Patients
The objectives of this pilot study are: 1. to determine whether a short cognitive test battery administered in the preadmission test center can be used to cognitively stratify elderly patients presenting for elective surgical…
- Trial name
- NCT01826825
- Testing
- Cognitive Screen, Mini-Cog
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Disability
Prospective Study and Analysis of Biomechanical Parameters of Human Movement Based on Disability Indicators in Older Adults
Mobility loss in older people is caused by a variety of aging impairments in various body systems.The disability, which includes physical impairments and resulting activity limitations or participation restrictions, can arise…
- Trial name
- MOBA-P (NCT05656690)
- Testing
- Exposure to disability
- Where
- Portugal
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Polytechnic Institute of Porto
Cannabis Use
Aging and Marijuana: Benefits, Effects, and Risks
Investigators will gather data on both the beneficial and harmful effects of edible cannabis of varying composition (THC-only vs. CBD-only vs.
- Trial name
- AMBER (NCT05188404)
- Testing
- Choice of cannabis product
- Where
- United States
- Volunteers
- 326 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Boulder
Osteoarthritis
Collaborative Lifestyle Intervention Program in Knee Osteoarthritis Patients
The Collaborative Lifestyle Intervention Program in Knee OsteoArthritis Patients (CLIP-OA) compares a novel community-based exercise and dietary weight loss program to the Arthritis Foundation's Walk with Ease intervention on…
- Trial name
- CLIP-OA (NCT02835326)
- Testing
- Exercise and Dietary Weight Loss, Walk with Ease
- Where
- United States
- Volunteers
- 227 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Effect of tDCS on Memory in Older and Younger Adults
Effect of Noninvasive Electrical Brain Stimulation on Memory at Different Times of Day in Younger and Older Adults
This study will investigate the extent to which tDCS to dorsolateral prefrontal cortex (or dlPFC) impacts memory performance as a function of time-of-day in younger and older adults.
- Trial name
- NCT03723850
- Testing
- Active tDCS
- Where
- United States
- Volunteers
- 271 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Covid19
Ligilactobacillus Salivarius MP101 for Elderly in a Nursing Home
The objective of this work was to investigate the effect of Ligilactobacillus salivarius MP101 on the functional (Barthel index), cognitive (GDS/FAST) and nutritional (MNA) status, and on the nasal and fecal inflammatory profiles…
- Trial name
- PROBELDERLY (NCT04922918)
- Testing
- Ligilactobacillus salivarius MP101
- Where
- Spain
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid
Microkinesitherapy
Effectiveness of Microkinesitherapy in Seniors
Many specialists stress that the aging process is individual, its course, severity and occurrence of disease are not the same for all seniors.
- Trial name
- NCT05494879
- Testing
- microkinesitherapy treatment
- Where
- Poland
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology
Older Adults With Decreased Outdoor Walking Ability
Getting Older Adults OUT-of -Doors
Community walking is an issue that older adults with chronic conditions have described as important to participation in the community.
- Trial name
- GO-OUT (NCT02339467)
- Testing
- GO-OUT program, Task-oriented outdoor walking workshop
- Where
- Canada
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- University of Manitoba
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