Clinical trials: Advanced Age
Cardiovascular Diseases, Hypertension
Uppsala Self-Screening of Cardiovascular Health
U-SCREEN is a randomized controlled trial evaluating whether systematic home-based multimodal screening for cardiovascular risk conditions, offered to residents in Region Uppsala turning 50, 55, 60, 65, 70 or 75 years of age, can…
- Conditions
- Cardiovascular Diseases, Hypertension, Dyslipidemias, Diabetes Mellitus
- Trial name
- U-SCREEN (NCT07614659)
- Testing
- Home-based multimodal cardiovascular screening
- Where
- Sweden
- Volunteers
- 45,000 people, healthy volunteers welcome
- Sponsor
- Johan Sundström
Aging, Sarcopenia
Effects of Resistance Training With High vs. Light-moderate Loads on Muscle-tendon Function in the Elderly
There are no unbiased studies that have analyzed the effects of resistance training with traditional, heavy versus light-moderate loads on muscle, tendon and bone in elderly people.
- Conditions
- Aging, Sarcopenia, Frail Elderly Syndrome
- Trial name
- NCT03724461
- Testing
- High Intensity resistance training (12 weeks), Light-moderate intensity resistance training (12 weeks), Control (12 weeks)
- Where
- Spain
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- University of Castilla-La Mancha
Healthy Elderly
Reference Values of Cerebrospinal Fluid Outflow Resistance and Intracranial Pressure in Healthy Elderly
Objective. The intracranial pressure and cerebrospinal outflow resistance are essential parameters to describe the cerebrospinal fluid dynamic system.
- Trial name
- NCT01188382
- Testing
- CSF dynamic investigation
- Where
- Sweden
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Umeå University
Nurse Training, Geriatric
Geriatric Nursing Training Program for Nursing Students
This research will be conducted using a parallel randomized controlled trial design to investigate the effects of a nursing education program grounded in Travelbe's Human-to-Human Relationship theory on willingness to work with…
- Conditions
- Nurse Training, Geriatric, Communication Skills, EMPATHY İN NURSİNG
- Trial name
- NCT07543627
- Testing
- Travelbee's Human-to-Human Relationship Theory-Based Geriatric Nursing Training Program
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Gazi University
Virtual Rehabilitation
Comparison of Effects of Interactive Video Games in the Elderly
The aim of this study is to assess the effectiveness of interactive video-games on mobility and wellbeing and to compare them with activity-based approaches in geriatric population.
- Trial name
- NCT03175588
- Testing
- Virtual Rehabilitation
- Where
- Turkey (Türkiye)
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- Istanbul University
Disability Physical, Social Acceptance
Promoting an incLUsive Society Towards Older Adults With Physical Disabilities
To improve secondary school students' positive attitudes towards older adults with physical disabilities via a Promoting an incLUsive Society towards older adults with physical disabilities through disability simulation education…
- Conditions
- Disability Physical, Social Acceptance, Respect
- Trial name
- NCT04993183
- Testing
- 3-day PLUS Convention
- Where
- Hong Kong
- Volunteers
- 1,111 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Age-related Strength Loss
High-Intensity Interval Training in a Community Gym
This study will deliver a 9 week high intensity interval training (HIIT) class using functional movements within a community based gym. The class will be twice a week.
- Trial name
- NCT06976060
- Testing
- High-Intensity Interval Training
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Creighton University
Exercise Intolerance, Aging
Heat Therapy and Muscle Function Study
Exercise tolerance decreases with age and a sedentary lifestyle. Muscle critical power (CP), is a sensitive measure of exercise tolerance that is more even more relevant to and predictive of endurance performance than VO2max.
- Conditions
- Exercise Intolerance, Aging, Heat Therapy, High Intensity Interval Training
- Trial name
- NCT04733287
- Testing
- High Intensity Interval Training of the Knee Extensors, Muscle Heat Therapy, Muscle Disuse
- Where
- United States
- Volunteers
- 148 people, healthy volunteers welcome
- Sponsor
- Brigham Young University
Healthy Volunteers
A Study of RSV-HMPV Bivalent Vaccine VXB-241 in Older Adults
The main purposes of this study are to assess the safety, reactogenicity and immunogenicity of 4 dose levels of the bivalent combination Respiratory Syncytial Virus (RSV) / human Metapneumovirus (hMPV) vaccine candidate VXB-241…
- Trial name
- NCT06556147
- Testing
- VXB-241 60 mcg (Low Dose), VXB-241 120 mcg (Medium Dose), VXB-241 240 mcg (Medium-high Dose)
- Where
- 4 sites in Australia
- Volunteers
- 144 people, healthy volunteers welcome
- Sponsor
- Sanofi
Insomnia, Sleep Initiation and Maintenance Disorders
Sleep Healthy Using The Internet for Older Adult Sufferers of Insomnia and Sleeplessness
This study will compare the efficacy of an interactive internet intervention for older adults with insomnia called SHUTi OASIS (Sleep Healthy Using the Internet for Older Adult Sufferers of Insomnia and Sleeplessness) accessed at…
- Trial name
- SHUTiOASIS (NCT03213132)
- Testing
- SHUTi (Sleep Health Using the Internet), Patient Education
- Where
- United States
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- University of Virginia
Biological Aging
Sex-specific Adaptation to Resistance Training in Older Adults
In general, men and women experience differing degrees of age-related decreases in physical function, with women having a greater prevalence of functional limitations and disability.
- Trial name
- NCT03440099
- Testing
- Resistance exercise training
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Amherst
Executive Dysfunction, Mild Cognitive Impairment (MCI)
Feasibility Study of Mixed Reality Exergame on Performance and Cortical Outcomes
The executive dysfunctions are a problem in individuals with MCI which predict conversion to dementia and is positively related to physical activity level.
- Trial name
- NCT06843733
- Testing
- Mixed reality exergame, Education
- Where
- Thailand
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease
Social Work Intervention Focused on Transitions
In response to Program Announcement (PA)-09-164, "NIH Exploratory/Developmental Research Grant Program (R21) a randomized pilot study testing the efficacy of SWIFT: Social Work Intervention Focused on Transitions among at-risk…
- Conditions
- Study Focus: 30-day Rehospitalizations Among At-risk Older Adults Randomized to a Social Work-driven Care Transitions Intervention, Heart Disease, Diabetes, Hypertension
- Trial name
- SWIFT (NCT02232126)
- Testing
- SWIFT home intervention
- Where
- 2 sites in United States
- Volunteers
- 181 people, healthy volunteers welcome
- Sponsor
- University of Southern California
BPPV
Benign Paroxysmal Positional Vertigo (BPPV) in Nursing Homes: Treatment Efficacy and Impact on Balance, Gait and Falls
BPPV is a benign condition of the balance organ, localized in the inner ear, in which calcium crystals loosen up and move freely in the endolymphatic fluid of the inner ear (more specifically in the semi-circular canals).
- Trial name
- NCT05013671
- Testing
- repositioning maneuvers, balance
- Where
- Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hasselt University
Gait Variability; Elders; Fall; Re-education
Effect of Observation Plus Imagination of Gait on Stride Variability in Young and Older Adults
The aim of study is to examine the combined effect of observation and imagination of gait on stride time variability of stride time among in healthy young and older adults.
- Trial name
- OBI (NCT02120144)
- Testing
- Observation & imagination, Reading
- Where
- France
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Ageing
Muscle Function Response to Resistance Band Training in Older Adults With Impaired Muscle Power
To investigate the effect of an fitness advice and resistance band exercise intervention on balance, muscle function, and power in an older people population who have low muscle power.
- Trial name
- NCT07672834
- Testing
- Resistance band exercise, Fitness advice
- Where
- United Kingdom
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Brunel University
Healthy Elderly
Effects of Exercise on Depression Symptoms, Physical Function, and Quality of Life in Community-Dwelling Elderly
The purpose of this study was to investigate the effects of 8-week exercise training on depression symptoms, physical functions, and quality of life in the community-dwelling elderly.
- Trial name
- NCT00931814
- Testing
- exercise training
- Where
- Taiwan
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Adverse Outcomes
Using Health Information Technology (HIT) to Improve Transitions of Complex Elderly Patients From Skilled Nursing Facility (SNF) to Home
The incidence of drug-induced injury is high in the ambulatory geriatric population, especially for elders with complex healthcare needs during high risk transitions to the ambulatory setting.
- Trial name
- RAMPAGEII (NCT01004328)
- Testing
- Intervention 1: Electronic medical record (EMR)-based transitional care intervention
- Where
- United States
- Volunteers
- 626 people, healthy volunteers welcome
- Sponsor
- University of Massachusetts, Worcester
Opioid-Related Disorders, Benzodiazepine-Related Disorders
De-prescribing Program to Evaluate Falls in Older Adults
Purpose: The proposed study will implement and evaluate the effect of an opioid and benzodiazepine (BZD) de-prescribing intervention on falls risk in older adults.
- Conditions
- Opioid-Related Disorders, Benzodiazepine-Related Disorders, Falls Injury
- Trial name
- NCT04272671
- Testing
- Educational Intervention
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Hospital-associated Deconditioning
Promoting Increased Physical Activity in Hospitalised Older Adults
The PIVOT study will explore the feasibility of training volunteers to deliver exercise to hospitalised older adults to improve the health of older people and prevent deconditioning while in hospital.
- Trial name
- PIVOT (NCT06017934)
- Testing
- Volunteer-led physical activity
- Where
- 2 sites in United Kingdom
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- University of Southampton
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