Clinical trials: Affect
Vasomotor Symptoms as a Sex Hormone-dependent Disorder in Women and Men, Hot Flashes
A Study to Learn if Elinzanetant Affects the Ability to Drive and Brain Function in Healthy Women
Researchers are looking for a better way to treat vasomotor symptoms (VMS), also known as hot flashes. Hot flashes are intense and sudden feelings of heat along with sweating and reddening of the skin.
- Trial name
- NCT06219902
- Testing
- Elinzanetant (BAY3427080), Zopiclone
- Where
- Canada
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Bayer
Depression Disorders
Couples' Affect in Relationships Study
The goal of this clinical trial is to find out whether learning about well-being impacts the thoughts and feelings of romantic couples.
- Trial name
- Cares (NCT06907654)
- Testing
- well-being app, List of well-being resources
- Where
- United States
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Obesity
Neurohormonal & Behavioral Correlates of Obesity and Weight Loss
Obesity has reached epidemic levels in the United States, and is on the rise in many industrialized nations. The rate of recidivism for long-term weight loss is substantial and presents a critical problem given the importance of…
- Trial name
- NCT02063451
- Testing
- Very Low Calorie Diet (VLCD)
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Michigan
COVID-19
A Study to Learn About How Loss of Liver Function Affects the Blood Levels of the Study Medicine Called PF-07817883.
The purpose of the study is to learn about the safety of PF-07817883 and how PF-07817883 is processed in the body of adult participants. These participants will have different degrees of loss of liver function.
- Trial name
- NCT05884554
- Testing
- PF-07817883
- Where
- 6 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Pfizer
Stress, Psychological Stress
Examine the Effects of Meditation on Daily Psychological Stress Responses in Woman With a History of Child Adversity
The aim of the Everyday Moments of Mindfulness (EMMI) study is to test whether brief mindfulness-based practices will improve daily psychological stress responses in women (age 30-60) who report a history of early life adversity.
- Conditions
- Stress, Psychological Stress, Child Maltreatment, Depressive Symptoms
- Trial name
- EMMI (NCT04606199)
- Testing
- Mindfulness-based intervention, up to 5 minutes 0-3 times/day
- Where
- United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cognitive Change, Affect
Cognitive Effects of Mint Essential Oil
This study investigates the cognitive and mood effects of mint essential oils in a group of healthy, human adults. The investigational product will also be tested in vitro to ensure a number of biological mechanisms.
- Trial name
- NCT03475836
- Testing
- Mentha piperita
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Healthy Adults
The Healthy Cookie Study: Understanding How Healthy Cookies Affect Fat in the Blood,
The purpose of this study is to understand how consuming healthy cookies every day for two weeks will affect different types of fat in the blood.
- Trial name
- NCT02841618
- Testing
- High Linoleic Acid Healthy Cookies, High Oleic Acid Healthy Cookies
- Where
- United States
- Volunteers
- 123 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Immune Mediated Inflammatory Diseases
A Trial to Learn How BAY1834845 and BAY1830839 Affect Inflammation When Taken by Mouth Twice a Day for 7 Days in a Row in Healthy Male Participants
The immune system helps protect the body from diseases. But, sometimes the immune system can be too sensitive and overreact to very small allergens, like dust and pet dander.
- Trial name
- NCT05003089
- Testing
- BAY1834845, BAY1830839, Prednisolone
- Where
- Netherlands
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Bayer
Neisseria Gonorrhoeae Infection, Chlamydia Trachomatis Infection
GonoScreen: Efficacy of Screening STIs in MSM
A Multicentre, controlled, randomized trial of 3 site (urethra, pharynx and rectum) sampling performed every 3 months (3x3) for Neisseria gonorrhoea (Ng)/Chlamydia trachomatis (Ct) screening (comparator) vs.
- Trial name
- GonoScreen (NCT04269434)
- Testing
- No Screening
- Where
- 5 sites in Belgium
- Volunteers
- 1,014 people, healthy volunteers welcome
- Sponsor
- Institute of Tropical Medicine, Belgium
Healthy Adult Male and Female Volunteers
Evaluating a Mat-Based Biometric Vibration System for Sleep and Daily Recovery
The goal of this randomized clinical trial is to learn whether a low-frequency "kinetic wellness" mat (a comfortable mat that gently vibrates) can improve stress recovery, sleep quality, mood, and attention in healthy adults ages…
- Trial name
- NCT07221318
- Testing
- Low-frequency whole-body vibration mat
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Florida International University
Negative Affectivity, Non-invasive Brain Stimulation
Neural Mechanisms of Interpersonal Expectations on Negative Affect
The goal of this clinical trial is to learn whether non-invasive brain stimulation, called transcranial temporal interference stimulation (tTIS), can reduce negative affect, and how expectations shaped by care providers influence…
- Conditions
- Negative Affectivity, Non-invasive Brain Stimulation, Placebo Effect, Expectations
- Trial name
- NCT06980090
- Where
- United States
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- Trustees of Dartmouth College
Dental Implant, Dental Implant Failed
Effect of Systemic Vitamin D on Dental Implant Osseointegration
The primary goal for any oral implantologist is to obtain satisfactory healing and long-term treatment success. Osseointegration is the key to dental implant success8 and is required to achieve direct structural and functional…
- Conditions
- Dental Implant, Dental Implant Failed, Vitamin D Deficiency
- Trial name
- VIDOS (NCT07684404)
- Testing
- Vit D
- Where
- Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Future University in Egypt
Wellbeing, Psychological Distress
Reflective Tasks With Healthcare Workers During COVID-19
The healthcare workforce is amongst the most stressed in the United Kingdom (UK). The Coronavirus (COVID-19) health pandemic has increased depression, anxiety, insomnia and distress in this population.
- Conditions
- Wellbeing, Psychological Distress, Emotional Distress, Depression
- Trial name
- NCT04728958
- Testing
- Gratitude
- Where
- United Kingdom
- Volunteers
- 117 people, healthy volunteers welcome
- Sponsor
- University of Sheffield
Chronic Kidney Disease, Healthy Volunteers
A Study to Learn How Safe the Study Treatment BAY3283142 is, How it Affects the Body, How it Moves Into, Through and Out of the Body When Single and Multiple Amounts Are Taken as Tablets in Japanese Healthy Male Participants
Researchers are looking for a better way to treat people who have chronic kidney disease (CKD). The kidneys filter extra water and waste out of the blood and make urine.
- Trial name
- NCT05800444
- Testing
- BAY3283142
- Where
- Japan
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Bayer
Emotional Regulation, Affect
Brief, Scaleable Intervention for Coronavirus (COVID-19) Mental Health Sequelae in College Students
The major aim of this pilot study is to evaluate a brief coping skills intervention for college students, based on an evidence-based treatment and delivered remotely via 14 short daily videos.
- Trial name
- NCT04558411
- Testing
- Dialectical Behavioral Therapy (DBT) Skills
- Where
- United States
- Volunteers
- 153 people, healthy volunteers welcome
- Sponsor
- Rutgers, The State University of New Jersey
Soil-transmitted Helminth Infection, Onchocerciasis (River Blindness)
A Study to Learn About How Much Emodepside Gets Absorbed in the Blood and How Food Affects Its Absorption When Given as a New Type of Tablet to Healthy Participants
Onchocerciasis or river blindness is an infectious disease caused by a parasitic worm. It spreads through the bite of an infected blackfly.
- Trial name
- NCT06412926
- Testing
- BAY 44-4400
- Where
- Germany
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Bayer
The Skeletal Effects of SSRIs
Do Serotonin Reuptake Inhibitors (SSRIs) Affect Bone Mass in Adolescents
Building on findings from animal studies, pediatric clinical trials, epidemiologic research in adults, and on preliminary findings from the investigators' laboratory in children and adolescents, this project aims to investigate…
- Trial name
- SSRI_BMD (NCT02147184)
- Where
- United States
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- Chadi A. Calarge
Prevention, Control
A Randomized Controlled Trial Testing the Effect of the Youth Mindful Awareness Program on Negative Affect (YMAP2).
The goal of this randomized clinical trial is to compare the effects of an online mindfulness program to an active supportive comparison condition and a no-intervention control group on reducing and preventing mood and anxiety…
- Trial name
- YMAP2 (NCT06526052)
- Testing
- Mindfulness Program, Active Comparator
- Where
- 3 sites in United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University
Blood Flow Restriction Training, Muscle Oxygenation
"How Blood Flow Restriction Exercise Affects Muscle Oxygenation and Lactate in Elite Athletes"
This study investigates the effects of blood flow restriction (BFR) training combined with low-intensity aerobic exercise on muscle oxygenation, total hemoglobin (THb), and blood lactate levels in elite athletes, comparing them…
- Conditions
- Blood Flow Restriction Training, Muscle Oxygenation, Physiological Adaptations
- Trial name
- NCT06918314
- Testing
- Blood Flow Restriction Kaatsu Training Device
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Eastern Mediterranean University
Coronary Artery Bypass Grafting, Preoperative Anxiety
Nurse Navigation Programs Affect to Anxiety, Perception of Quality Nursing Care and Stress Hormone Levels
This study aims to evaluate the effect of a nurse-led preoperative navigation program on preoperative anxiety, perceived quality of perioperative nursing care, and serum cortisol levels in patients undergoing coronary artery…
- Trial name
- NCT07528989
- Testing
- Nursing navigation program
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Uludag University