Clinical trials: Age Problems
Aging Problems
Treatment Strategy to Enhance Nrf2 Signaling in Older Adults
Exercise is the cornerstone of disease prevention and often an important component of treatment. However, the efficacy of an exercise stimulus is reduced with aging.
- Trial name
- NCT04848792
- Testing
- Sulforaphane
- Where
- United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Northern Arizona University
Polypharmacy, Potentially Inappropriate Medications
A Pharmaceutical Intervention to Reduce Drug-Related Problems in a Home Healthcare Program
The investigators' hypothesis is that the individualized review of the pharmacotherapeutic plans of patients in a home healthcare program will be effective in improving the quality and safety of treatments.
- Trial name
- NCT05820945
- Testing
- Pharmacist-led medication review
- Where
- Spain
- Volunteers
- 432 people
- Sponsor
- Fundacio d'Investigacio en Atencio Primaria Jordi Gol i Gurina
Cardiovascular Diseases, Cardiovascular Risk Factor
Chinese Multi-provincial Cohort Study-Beijing Project
The Chinese Multi-provincial Cohort Study (CMCS)-Beijing project is a sub-study in CMCS participants from Beijing, which intended to investigate the progression and determinants of atherosclerosis and aging related health…
- Conditions
- Cardiovascular Diseases, Cardiovascular Risk Factor, Aging Problems, Smell Disorder
- Trial name
- CMCS-Beijing (NCT04253054)
- Testing
- Cardiovascular risk factors, Aging related health problems
- Where
- 3 sites in China
- Volunteers
- 3,000 people
- Sponsor
- Beijing Institute of Heart, Lung and Blood Vessel Diseases
Age Problem
Impact of a Hospital Medication Expertise on Unplanned Hospitalizations at 3 Months of Nursing Homes Patients
The use of drugs in the elderly population remains a major public health problem worldwide. Technological advances and the development of new drugs have helped to extend life expectancy.
- Trial name
- TEM-EHPAD (NCT03640845)
- Testing
- tele-expertise
- Where
- France
- Volunteers
- 364 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Age Problem, Abdominal Cancer
Dosage of Epidural Morphine in Elderly Patients
This a clinical trial that evaluates the efficacy and safety of three different doses of morphine, namely 1.5 mg, 3 mg and 4.5 mg, via the epidural route regarding reducing pain in elderly patients after a cancer surgery in the…
- Trial name
- NCT04316871
- Testing
- 1.5 mg of Morphine Sulfate, Normal saline, 3 mg of Morphine Sulfate
- Where
- Egypt
- Volunteers
- 96 people
- Sponsor
- Assiut University
Chronic Disease, Chronic Condition
Feasibility and Potential Impact of an Individualized Exercise Program Via a Telerehabilitation Device in Chronic Patients: A Pilot Study
Exercise Rehabilitation (ER) is widely used and effective in the treatment of chronic diseases; however, patients do not adhere to ER programs.
- Conditions
- Chronic Disease, Chronic Condition, Stroke Sequelae, Age Problem
- Trial name
- NCT06558591
- Testing
- Telerehabilitation intervention
- Volunteers
- 50 people
- Sponsor
- Limoges University
Hypertension, Stress
Effect of Different Pranayama Breathing Techniques on Quality of Life in Hypertensive Patients
The purpose of the current study is to compare between the effect of Bhramari pranayama versus Sheetali pranayama on quality of life in hypertensive patients.
- Conditions
- Hypertension, Stress, Aging Problems
- Trial name
- NCT05651854
- Testing
- pranayama breathing
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Cairo University
Resilience, Depressive Symptom
Musical Training to Enhance Resilience of Underprivileged School-aged Children
This is a multi-centre randomised controlled trial aims to examine the effects of a group-based gamified instrumental musical training in enhancing resilience (primary outcome), reducing psychological distress (depressive…
- Conditions
- Resilience, Depressive Symptom, Anxiety
- Trial name
- NCT07165925
- Testing
- Gamified music training
- Where
- Hong Kong
- Volunteers
- 174 people
- Sponsor
- Chinese University of Hong Kong
Ostomy, Living in Roskilde County
Skin Problems in Ostomy Patients: An Epidemiological Study
Peristomal skin complications are thought to be common but the exact frequency and cause of these complications are unknown. We have sought to document the incidence of cutaneous peristomal problems and to find risk factors that…
- Conditions
- Ostomy, Living in Roskilde County, Persons More Than 18 Years of Age, Willingness to Participate
- Trial name
- NCT00391508
- Where
- Denmark
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Emotional Problem
Emotional Problems in Preschool Children: Evaluation of the SuperKids Program (PRE-KIDS)
Emotional problems are among the most frequent psychological problems in the school stage, having an early onset. When they are not detected and they do not receive adequate intervention, they persist and become chronic, being…
- Trial name
- NCT06419933
- Testing
- The SuperKids Program
- Where
- Spain
- Volunteers
- 500 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Medication-related Problems, Self-reported Medication Adherence
Improving Medication Therapy Through a Digital Interdisciplinary Medicine Therapy Optimisation Model
In this study, a telepharmacy service in primary care for home-living older adults in Northern Sweden's rural areas will be developed and evaluated.
- Conditions
- Medication-related Problems, Self-reported Medication Adherence, Health-related Quality of Life, Beliefs About Medicines
- Trial name
- MTO (NCT05629936)
- Testing
- Telepharmacy service
- Where
- 2 sites in Sweden
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Umeå University
Adverse Drug Events
Drug-Related Problems : Focus on Age and Diabetes
Drug-Related Problems (DRP) are a variety of events or circumstances that can interfere with the expected results of a treatment.
- Trial name
- DRP-AD (NCT04692220)
- Testing
- Detection of Adverse Drug Events or Drug-Related Problems
- Where
- France
- Volunteers
- 27,000 people
- Sponsor
- University Hospital, Montpellier
Sleep Problems, Maternal Anxiety
Sleep Patterns in Children Aged 0-36 Months and Maternal Anxiety and Depression
In this study, the investigators aimed to investigate the relationship between the sleep patterns of children aged 0-36 months hospitalized in the general pediatrics clinic and their mothers' anxiety and depression levels.
- Trial name
- NCT07476612
- Where
- Turkey (Türkiye)
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Başakşehir Çam & Sakura City Hospital
Skin Aging, Facial Asymmetry
Comparison of an Office-based Limited Facelift and Hospital-based Full Facelift
To compare safety, patient satisfaction, and technical correction between a limited and full facelift, patients meeting strict clinical and safety criteria for both types of facelift will be randomly assigned to have one of these…
- Conditions
- Skin Aging, Facial Asymmetry, Aging Problems
- Trial name
- COAL2 (NCT05419609)
- Testing
- Limited facelift, Full facelift, FACE-Q | Aesthetics - Satisfaction With Lower Face and Jawline
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Dufresne, Craig, MD, PC
HIV, Frailty
Improving Physical Ability and Cellular Senescence Elimination in HIV
This clinical trial is a Phase II study designed to test the safety and effectiveness of a combination of dasatinib and quercetin (D+Q) in improving physical function for people with HIV who are frail or prefrail.
- Conditions
- HIV, Frailty, Prefrail, Aging Problems
- Trial name
- IPACE-HIV (NCT07144293)
- Testing
- Dasatinib, Quercetin
- Where
- 24 sites in United States
- Volunteers
- 82 people
- Sponsor
- National Institute of Allergy and Infectious Diseases (NIAID)
Ageing
The OMAGE (Optimization of Medication in AGEd) Transitional Care-Pathway: Impact on Readmissions
Background : The transitional care OMAGE-P combines three best practices recommendations from the French National Authority for Health (HAS) (i) a comprehensive review of diagnosis and treatments (ii) a standardized medical…
- Trial name
- OMAGE-P (NCT02657642)
- Volunteers
- 484 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Cancer
Cancer in the Elderly: Prevalence and Impact of Age Related Problems
About 50% of cancer patients are >70 years at diagnosis. Age related somatic and psychiatric problems may influence the course of cancer and its treatment. The present study is a prospective observational study.
- Trial name
- NCT01742442
- Where
- 3 sites in Norway
- Volunteers
- 307 people
- Sponsor
- Sykehuset Innlandet HF
Sleep, Cognitive Impairment
Observational Study About Sleep Quality and Its Impact on Daily Life of Nursing-home Residents
Introduction: Poor sleep quality is common in most older adults. Because of the progressive aging of the population in Spain, there are more and more nursing-home and day centers, which give care to older adults.
- Conditions
- Sleep, Cognitive Impairment, Quality of Life, Age Problem
- Trial name
- NCT04592796
- Testing
- Xiaomi MiBand2, Socio-demographic questionnaire, EuroQol-5D-5L
- Where
- Spain
- Volunteers
- 21 people
- Sponsor
- Universidade da Coruña
Stroke, Aging Problems
Innovative Models in the Rehabilitation of the Elderly With Stroke Through Technological Innovation
The final goal of the present study is to propose a new approach and an innovative therapeutic plan in the post-stroke rehabilitation of elderly patients, focused on the use of robotic device, in order to obtain the beneficial…
- Conditions
- Stroke, Aging Problems, Innovative Rehabilitation Treatment Based on Robotics
- Trial name
- NCT04087083
- Testing
- Technological intervention arm, Control arm
- Where
- 2 sites in Italy
- Volunteers
- 150 people
- Sponsor
- Istituto Nazionale di Ricovero e Cura per Anziani
Aging Problems
Explore Effects of Dietary Fish Oil in Human Skin
The purpose of this study is to explore the potential differences in the skin of people who take fish oil versus soybean oil pills.
- Trial name
- NCT03122912
- Testing
- Fish Oil, Soybean Oil
- Where
- United States
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- University of Michigan