Clinical trials: Aggression
Mantle Cell Lymphoma
Bortezomib After Combination Chemotherapy, Rituximab, and an Autologous Stem Cell Transplant in Treating Patients With Mantle Cell Lymphoma
This randomized phase II trial studies how well bortezomib works when given after combination chemotherapy, rituximab, and an autologous stem cell transplant in treating patients with mantle cell lymphoma.
- Trial name
- NCT00310037
- Testing
- bortezomib
- Where
- 48 sites in United States
- Volunteers
- 151 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Hodgkin's Lymphoma - Relapsed/Refractory, Non-Hodgkin's Lymphoma - Aggressive
GEMHDM2014 : Gem-HDM HDT and ASCT for Relapsed/ Refractory Lymphoma
Objective of study: To evaluate the safety and efficacy of infusional gemcitabine prior to HDM (high-dose melphalan) as HDCT (High Dose Chemotherapy) followed by autologous stem cell transplantation in patients with…
- Conditions
- Hodgkin's Lymphoma - Relapsed/Refractory, Non-Hodgkin's Lymphoma - Aggressive, Follicular Lymphoma
- Trial name
- GEMHDM2014 (NCT02295722)
- Testing
- Gemcitabine, Melphalan, ASCT
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- AHS Cancer Control Alberta
Cyberbullying
The Effect of Web-Based Cyber Sexual Violence Training on Cyber Sexual Violence Experience, Sensitivity and Security
The aim of this study is to provide web-based cyber sexual violence training with a model (Knowledge, Motivation, Behavior Skills (IMB) Model) to female university students, who are one of the groups that are vulnerable to being…
- Trial name
- NCT06408831
- Testing
- Classroom Teaching University Students Intervention Group
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Inonu University
Schizophrenia
Clozapine IM and Aggression in Schizophrenic Patients
Aggressive, persistent aggression and impulsive behavior are frequently observed in schizophrenic patients. According to some researchers "more than 50% of all psychiatric patients and 10% of schizophrenic patients show…
- Trial name
- NCT00189995
- Testing
- clozapine, haloperidol
- Where
- 2 sites in Israel
- Sponsor
- Beersheva Mental Health Center
Leukemia, Lymphocytic, Lymphoma
Study of Intravenous BCX-1777 in Relapsed or Refractory Aggressive T-Cell Leukemias or Lymphomas
The purpose of this study is to determine if intravenous BCX-1777 can be given safely to improve relapsed or refractory aggressive T-cell leukemias and lymphomas.
- Trial name
- NCT00035022
- Testing
- BCX-1777
- Where
- United States
- Volunteers
- 71 people
- Sponsor
- BioCryst Pharmaceuticals
Neoplasms
Phase I Dose Escalation Study for VIP152 in Patients With Advanced Cancer
Determine the safety, tolerability, pharmacokinetics, maximum tolerated dose (MTD) and recommended phase 2 dose (RP2D) of VIP152 (BAY 1251152) as monotherapy or in combination in patients with solid tumors and aggressive…
- Trial name
- NCT02635672
- Testing
- VIP152 (BAY 1251152), VIP152 (BAY 1251152) 30 mg, Keytruda
- Where
- 16 sites in United States, Chile and 1 more
- Volunteers
- 110 people
- Sponsor
- Vincerx Pharma, Inc.
Molar-incisor Pattern Grade C Periodontitis ( Localized Aggressive Periodontitis), Generalized Grade C Periodontitis (Generalized Aggressive Periodontitis)
Apoptosis Markers in Aggressive Periodontitis
The aim of the present trial is to assess the gingival crevicular fluid level of caspase-3 and apoptosis inducing factor (AIF) in Generalized versus Molar-incisor grade C periodontitis.
- Trial name
- NCT04984031
- Testing
- ELISA assessment of apoptosis markers in gingival crevicular fluid
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Asem Mohammed Kamel Ali
Dementia, Pain
Aggression Prevention Training for Caregivers of Persons With Dementia (APT)
This study will evaluate whether a home-based targeted education and skill training (Aggression Prevention Training or APT) will reduce aggression in persons with dementia (PWD) and pain/pain-related features more than usual care…
- Conditions
- Dementia, Pain, Alzheimer's Disease, Aggression
- Trial name
- APT (NCT02380703)
- Testing
- Aggression Prevention Training (APT), Enhanced Usual Primary Care (EU-PC)
- Volunteers
- 239 people
- Sponsor
- Baylor College of Medicine
Dementia, Aggression
Preventing Aggressive Behavior in Demented Patients
The purpose of this study is to develop and pilot test and non-pharmacological intervention designed to prevent the occurence of aggression in persons with dementia.
- Trial name
- PAVeD (NCT00622128)
- Testing
- Preventing Aggressive Behavior in Demented Patients
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- US Department of Veterans Affairs
Bullying and Victimization
The Effect of Awareness Training on Peer Bullying
This study examined the effect of awareness training on peer bullying, victimization, empathy, and sympathy levels in adolescents. A total of 64 students were randomly assigned to an intervention group or control group.
- Trial name
- NCT07383545
- Testing
- Awareness training on peer bullying
- Where
- Turkey (Türkiye)
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Selcuk University
Anger Problems, Aggression
Treatment of Chronic Anger and Aggression Following Military-Related Betrayal
The goal of this clinical trial is to learn if a treatment designed to deal with anger and aggression from a past betrayal will work. The study will be done on active duty military service members and veterans aged 18 or older.
- Trial name
- CART (NCT06609330)
- Testing
- Countering Chronic Anger and Aggression Related to Trauma and Transgressions (CART)
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Aggression, Self-injurious Behavior
Refinements of Functional Communication Training
Although treatments for problem behavior, like functional communication training (FCT), can be highly effective in the clinic, changes in the way the FCT is implemented (e.g., when transferring treatment to the home, when…
- Trial name
- NCT04045600
- Testing
- Trad FCT, Mult FCT, Mult FCT + Stimulus Fading
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Rutgers, The State University of New Jersey
Disruptive Behavior, Aggression Childhood
Digital Parent Training for Disruptive Behaviors in Children
This is an open pilot trial of web-based parent training for tantrums and disruptive behavior in children. Parents will be asked to complete a battery of tests to assess their children' behaviors before and after the…
- Conditions
- Disruptive Behavior, Aggression Childhood, Anger, Non-Compliance, Patient
- Trial name
- NCT03697837
- Testing
- Parent Management Training
- Where
- United States
- Volunteers
- 16 people
- Sponsor
- Yale University
Aggressive Variant Prostate Carcinoma
Zanzalintinib in Men With Aggressive Variant Prostate Cancer
This is a multi-center single arm phase II study to evaluate the antitumor activity of zanzalintinib 60mg orally (PO) once daily in subjects with AVPC.
- Trial name
- NAPOLEON (NCT07218666)
- Testing
- Zanzalintinib
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Deepak Kilari
Metastatic Castration-Resistant Prostate Cancer
XmAb®20717 (Vudalimab) Alone or in Combination With Chemotherapy or Targeted Therapy in Patients With Metastatic Castration-Resistant Prostate Cancer
This Phase 2 study will investigate the safety and clinical activity of vudalimab (XmAb20717) alone or in combination with standard of care anticancer therapies in patients with metastatic castration-resistant prostate cancer…
- Trial name
- NCT05005728
- Testing
- vudalimab + carboplatin + cabazitaxel, vudalimab + olaparib, vudalimab monotherapy
- Where
- 26 sites in United States
- Volunteers
- 72 people
- Sponsor
- Xencor, Inc.
Cyberbullying
Peer Group Training vs Direct Instruction to Reduce Cyberbullying Among High School Boys"
This study aims to explore ways to reduce cyberbullying among male high school students in Tehran by comparing two types of training: direct instruction from a psychologist and peer-led training.
- Trial name
- CyberPeer (NCT07204730)
- Testing
- Direct Social Skills Training, Peer-Led Social Skills Training, Control No Training
- Where
- Iran
- Volunteers
- 252 people, healthy volunteers welcome
- Sponsor
- Ahvaz Jundishapur University of Medical Sciences
Borderline Personality Disorder
Guanfacine to Treat Borderline Personality Disorder
This study is designed to investigate whether guanfacine (Tenex) is an effective treatment for borderline personality disorder (BPD), an illness often characterized by unstable mood and impulsive aggression.
- Trial name
- NCT00358969
- Testing
- guanfacine (Tenex)
- Where
- United States
- Sponsor
- Icahn School of Medicine at Mount Sinai
Intermittent Explosive Disorder, Childhood Aggression
Intuniv vs Placebo in the Treatment of Childhood Intermittent Explosive Disorder
Children with explosive aggression are often rejected by their peers, placed in special classroom, and contribute to family discord. When psychotherapy and family therapy is unsuccessful, medications are often used.
- Conditions
- Intermittent Explosive Disorder, Childhood Aggression, Oppositional Defiant Disorder, Attention Deficit Disorder
- Trial name
- NCT02048241
- Testing
- Parent Management Training, Intuniv
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- New York State Psychiatric Institute
Aggression, Adolescence
Wise Intervention for Reducing Aggressive Behaviors and Promoting Prosocial Behaviors Toward LGB-TNB Individuals
This study evaluates the effectiveness of a wise Intervention to reduce aggressive behaviors and promote prosocial behaviors toward LGB-TNB individuals among Spanish adolescents.
- Trial name
- LGB-TNB (NCT07212283)
- Testing
- Wise Intervention LGB-TNB, Values alignment wise intervention
- Where
- Spain
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- University of Deusto
Anger, Stress
Hostile Bias Modification Training (HBMT) Study
The primary objective of the present protocol is to evaluate the effectiveness of real HBMT versus placebo on reducing HAB and aggression. The secondary objectives of the present protocol are: 1.
- Conditions
- Anger, Stress, Aggression
- Trial name
- NCT04997356
- Testing
- Hostile Bias Modification Training, Other training
- Where
- United States
- Volunteers
- 165 people, healthy volunteers welcome
- Sponsor
- Walter Reed Army Institute of Research (WRAIR)