Clinical trials: Aging Problems
Frailty, Frailty Syndrome
Prevalence, Determinants and Natural History of Frailty and Pre-frailty in Elderly People
Frailty syndrome (i.e. frailty) is a geriatric syndrome which relies on the reduction of multisystem reserve capacity. Frail people have a lower potential to respond to external stressors and various life incidents as well as…
- Conditions
- Frailty, Frailty Syndrome, Frail Elderly Syndrome, Fragility
- Trial name
- FRAILPOL (NCT04518423)
- Where
- Poland
- Volunteers
- 1,093 people, healthy volunteers welcome
- Sponsor
- The Opole University of Technology
Age Problem, Disability
China Healthy Aging Cohort Study
This is a community-based prospective cohort study in China. The study has been initialized in 2024 and included older residents.
- Conditions
- Age Problem, Disability, Dementia, Death
- Trial name
- China-Ageing (NCT06472674)
- Testing
- No intervention
- Where
- China
- Volunteers
- 6,780 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Aging Problems
Effects and Dose-response of Manual Therapy in the ROM of the Ankle in Older People
Limitations of the joint range of the ankle in elderly people is usually common. One of the ways to treat this limitation is through manual therapy, although the effects it produces in dose-response terms are still not well…
- Trial name
- ANKLE_ROM (NCT03600402)
- Testing
- Experimental, Control
- Where
- Spain
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Aging Problems
Dose-response of Talus Mobilizations
Ankle mobility limitations are common in older adults. A possible treatment to restore joint mobility is manual therapy based on mobilization techniques, in this case, applied on the ankle joint.
- Trial name
- ANKLE_ROM (NCT04360512)
- Testing
- Posteriorization of the talus
- Where
- Spain
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Social Isolation, Loneliness
The CONNECT Program: Testing a Telephone-Based Mental Health Intervention for Older Adults
This study will test a telephone-based group intervention called "The CONNECT Program" which is designed for adults aged 65+ who are currently experiencing social isolation or loneliness, and symptoms of anxiety or depression.
- Conditions
- Social Isolation, Loneliness, Depression, Anxiety
- Trial name
- CONNECT (NCT05120765)
- Testing
- The CONNECT Program
- Where
- Canada
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Manitoba
Aging Problems, Frailty
Impact of Skills Acquired Through Judo Training on Risk Factors for Falling in Elderly Men and Women
Falls and injuries from falls are one of the greatest threats to public health. One of the risk factors for accidental falls is a low self-efficacy regarding the perceived capability to perform activities without the risk of…
- Conditions
- Aging Problems, Frailty, Fall Injury, Accidental Fall
- Trial name
- J4BE (NCT04061785)
- Testing
- Judo4Balance - 12 week judo inspired exercise program
- Where
- Sweden
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Dalarna University
Memory Deficits, Mood Change
The Effects of Microbiological Spectrum Changes to Improve Cognitive Health in Aging Population
The goal of this project is to develop probiotic dietary supplements intended for the elderly, which can modify the composition of the intestinal microbiota typically occurring in the aging population.
- Conditions
- Memory Deficits, Mood Change, Gut Health, Aging Problems
- Trial name
- CleverAgeBiota (NCT05051501)
- Testing
- Probiotics C2P
- Where
- 2 sites in Czechia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Institute of Mental Health, Czech Republic
Fall, Age Problem
A Specific Dance Intervention in Older Adults in Hong Kong
This study is a fully-powered randomised controlled trial and an essential follow-up study of our pilot work. The 21-style specific dance intervention to improve the balance and reduce the risks of falls (SDIIBRF) was suggested…
- Trial name
- NCT06563661
- Testing
- The 21-style specific dance exercises
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Hong Kong Polytechnic University
Disability Physical, Disabilities Mental
Combined Motor and Cognitive Training for Older Adults With Motoric Cognitive Risk Syndrome (CMC-training)
To investigate the effects of a combined motor-cognitive intervention on the improvement of motor as well as cognitive function in community residents.
- Conditions
- Disability Physical, Disabilities Mental, Age Problem
- Trial name
- NCT06542601
- Testing
- Motor cognitive intervention
- Where
- China
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- Xuanwu Hospital, Beijing
Age Problem
Efficacy of the Otago Exercise Program Delivered as Group Training Versus Individually Tailored Training
A non-inferiority controlled clinical trial using randomization for allocation at the level of general practice in 21 centers (in 8 Spanish regions), to compare a group Otago exercise program (OEP) [delivered by specifically…
- Trial name
- NCT03320668
- Testing
- Otago Exercise Program (OEP)
- Where
- 9 sites in Spain
- Volunteers
- 878 people, healthy volunteers welcome
- Sponsor
- Instituto de Salud Carlos III
Age Problem
The SUMAMOS EXCELENCIA Project: Assessment of Implementation of Best Practices in a National Health System
There is a gap between research and clinical practice, leading to variability in decision-making. Clinical audits are an effective strategy for improving implementation of best practices.
- Trial name
- NCT03725774
- Testing
- GRIP (Getting Research into Practice) model
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Teresa Moreno Casbas
Aging Problems
Enhancing Care of the Aged and Dying in Prisons Ph II
The mission of corrections is to provide custody, control and care for incarcerated individuals. United States prisons are required by constitutional law to provide adequate care for growing numbers of older inmates who will…
- Trial name
- NCT03055429
- Testing
- Full Scale Unit
- Where
- 2 sites in United States
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Aging Problems
E-training of Inmate Peer Caregivers for Enhancing Geriatric and End-of-life Care in Prisons
The mission of corrections is to provide care, custody, and control for incarcerated individuals. United State prisons are required by constitutional law to provide adequate care for growing numbers of older inmates who will…
- Trial name
- P2P (NCT03323008)
- Testing
- Prototype
- Where
- 2 sites in United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Klein Buendel, Inc.
Aging Disorder, Age Problem
Health Status and Its Socio-economic Covariates of the Older Population in Poland - the Nationwide PolSenior2 Survey.
The PolSenior2 survey is aimed to characterise health status of old and very-old adults in Poland.
- Conditions
- Aging Disorder, Age Problem, Healthy Aging, Immunity Disorders
- Trial name
- PolSenior2 (NCT04026815)
- Testing
- medical history, blood and urine tests
- Where
- Poland
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Medical University of Gdansk
Depression
Promoting Sleep and Healthy Aging Research Study (PRO-SHARE)
The objective of this study is to evaluate the ability of a behavioral intervention, cognitive behavioral therapy for sleep quality (CBT-SQ) to reduce sleep complaints, depression recurrence, and cellular and genomic markers of…
- Trial name
- PRO-SHARE (NCT01641263)
- Testing
- Sleep Education Therapy, Cognitve Behavioral Therapy for Insomnia
- Where
- United States
- Volunteers
- 308 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Aging Problems
Vascular Aging and Microcirculation: Physiological Aspects of Vascular Aging in the Elderly Population (VAMP-Aging)
Rising life expectancy worldwide challenges public health due to increased cardiovascular disease linked to vascular aging, where microvascular dysfunction serves as an early indicator of system-wide inflammation, or…
- Trial name
- VAMP-Aging (NCT07563725)
- Testing
- Laser Speckle Contrast Imaging, Handgrip Dynamometry (Muscle Strength), Sit-to-Stand Test (5-Times Sit-to-Stand - 5STS)
- Where
- Brazil
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- National Institute of Cardiology, Laranjeiras, Brazil
Chronic Disease, Aging
Student-delivered Telehealth Program for COVID-19 Education and Health Promotion
The purpose of this study is to ensure effective health management among community-living older adults during unprecedented times, such as the current COVID-19 pandemic.
- Conditions
- Chronic Disease, Aging, Aging Problems, Health Behavior
- Trial name
- NCT04492527
- Testing
- Telehealth coaching sessions
- Where
- Canada
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Auditory Perceptual Disorders, Aging Problems
Neuroplasticity in Auditory Aging_Project 2 Aims 1 and 2
Millions of elderly adults in the USA have age related hearing loss (ARHL), a malady that affects half of adults 60-69 years, and the majority of older adults.
- Trial name
- NCT03475043
- Testing
- Auditory training: temporal cues
- Where
- United States
- Volunteers
- 405 people, healthy volunteers welcome
- Sponsor
- University of Maryland, College Park
Problem of Aging
Volume Restoration of the Aging Midface With Sculptra Aesthetic
The purpose of this study is to examine the effect of Sculptra Aesthetic on the cosmetic rejuvenation of the midface complex. The investigators plan to both qualitatively determine the restoration of midface architecture as well…
- Trial name
- NCT01307865
- Testing
- injectable poly-L-lactic acid
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Williams Center Plastic Surgery Specialists
Sedentary Lifestyle, Age Problems
Nordic Walking Training for Older People
Objective: to assess by means of a randomized clinical trial the effects of eight weeks of Nordic walking and free walking training on quality of life (QoL), static balance, dynamic variability, self-selected walking speed (SWS)…
- Trial name
- Pole walking (NCT03096964)
- Testing
- Free walking training, Nordic walking training
- Where
- Brazil
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Federal University of Rio Grande do Sul