Clinical trials: Air Leak From Lung
Lung Cancer Stage I, Lung; Node
Intra-operative Air Leak Management After Minimally Invasive Lung Segmental Resection
In patients undergoing minimally invasive thoracoscopic surgery (video-assisted thoracoscopic surgery, or VATS), a still unsolved issue is represented by intraoperative alveolar air leaks (IOAALs), which if prolonged beyond the…
- Conditions
- Lung Cancer Stage I, Lung; Node, Air Leak From Lung
- Trial name
- NCT06544200
- Testing
- Polymeric Hydrogel Matrix
- Where
- Italy
- Volunteers
- 104 people
- Sponsor
- University Hospital Padova
Air Leak From Lung
Air Leak Detection and Treatment
Developing a methodology to detect, quantify and treat air leaks intraoperatively using a bio-adhesive, to thereby reduce postoperative surgical complications, morbidity, and length of stay for patients undergoing pulmonary…
- Trial name
- CT0128 (NCT05854654)
- Testing
- Air Leaks
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Air Leak From Lung, Pneumothorax
Feasibility and Accuracy of a Novel Pleural Drain Gas Analyzer in Detecting Air Leaks
The goal of this study is to assess the clinical feasibility of a novel, reusable, low cost gas analyzer that detects breath in chest drains in order to diagnose and heal air leaks.
- Trial name
- NCT06548386
- Testing
- Pleural gas analysis
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Lung Healing Technologies Inc
Air Leak From Lung
Pleurodesis Using Hypertonic Glucose
Air leaks from unhealed lung tissue following lung resection for benign or malignant lesions are one of the most common complications following thoracic surgery, occurring after 10% of major lung resections.
- Trial name
- PLUG-II (NCT06293885)
- Testing
- Dextrose 50, Standard of Care - No Dextrose 50
- Where
- Canada
- Volunteers
- 40 people
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Air Leak From Lung
Comparison of Two Different Pleural Drainage Systems
The digital pleural drainage system Topaz+ by Medela is compared to the analogue system Atrium OCEAN by Maquet in patients undergoing cardiac surgery. The study is prospectively randomized with an all-comer setup.
- Trial name
- NCT03021369
- Testing
- Pleural drainage system
- Where
- Germany
- Volunteers
- 374 people
- Sponsor
- Kerckhoff Klinik
Respiratory Insufficiency
Evaluation of Leak-free Bronchoscope Adapter
Patients who develop respiratory failure require the assistance of mechanical ventilation while recovering from their respiratory injury.
- Trial name
- NCT05288218
- Testing
- Leak-free Bronchoscope Adapter, Standard Bronchoscope Adapter
- Volunteers
- healthy volunteers welcome
- Sponsor
- Columbia University
Pulmonary Disease
Evaluation of Leak-Free Bronchoscope Adapter to Limit Ventilated Air Volume Loss During Bronchoscopy
The purpose of this research is to evaluate the ability of a new bronchoscope adapter called "leak-free adapter" to limit the amount of air leaking out to the operating room (OR) from the ventilator in intubated patients who…
- Trial name
- NCT06310577
- Testing
- Leak-free bronchoscope adapter
- Where
- United States
- Sponsor
- Endeavor Health
Air Leak From Lung, Post Procedural Persistent Drain Fluid
Silastic Versus Conventional Drain in Thoracic Surgery
In thoracic surgery, it is usual to place apical and basal drains for complete drainage of air and fluid out of the pleural cavity. The routinely used drains are mainly made of plastic.
- Trial name
- SD-CD (NCT03056716)
- Testing
- Silastic vs conventional drain in thoracic surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 118 people
- Sponsor
- T.C. Dumlupınar Üniversitesi
Air Leak From Lung
Hemopatch Compared to TachoSil in Postoperative Air Leak Duration After Pulmonary Resection
This study is a randomized, controlled study, with the primary objective to demonstrate non-inferiority of Hemopatch compared to TachoSil in postoperative air leak duration after pulmonary resection, and with the secondary…
- Trial name
- NCT03450265
- Testing
- Hemopatch, Tachosil
- Where
- 14 sites in Italy, Spain
- Volunteers
- 279 people
- Sponsor
- Baxter Healthcare Corporation
Air Leak From Lung, Lung Surgery
Prospective Study Evaluating the Effectiveness of Intraoperative Ventilation for Predicting Postoperative Air Leaks During Major Lung Resections by Conventional or Robotic Thoracoscopy
Air leak from lung after major pulmonary resections is alveolar-pleural microfistulas resulting from damage to the visceral pleura during lung surgery.
- Trial name
- NODRAIN (NCT07350265)
- Testing
- No Intervention: Observational Cohort
- Where
- France
- Volunteers
- 100 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Air Leak From Lung
Pneumostasis With Use of Bio-absorbable Mesh and Fibrin Sealant in Lung Resection
Prolonged air leak, defined as air leak present 5 days after lung resection, is one of the most common complications after lung resection.
- Trial name
- NCT04317924
- Testing
- Polyglycolic acid felt, Standard of care
- Where
- United States
- Sponsor
- Boston Medical Center
Air Leak From Lung
Validation of a System Using Aerosol Glycerine to Detect and Localize Intraoperatively Pulmonary Air Leaks
Air leaks represent one of the most common complications and postoperative morbidity in thoracic surgery. Air leaks have been associated with the largest preventable morbidity associated with increased costs following lobectomy…
- Trial name
- CT0136 (NCT05971719)
- Testing
- Air Leaks: Aerosol glycerine System
- Where
- Canada
- Volunteers
- 200 people
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)
Lung Neoplasms, Pulmonary Surgical Procedures
Staple-line Reinforcement for Prevention of Pulmonary Air Leakage
The aim of this study is to compare the efficacy of FORESEAL with stapling alone or associated with tissue sealant or glue in terms of air leakage duration after lung resection for cancer.
- Conditions
- Lung Neoplasms, Pulmonary Surgical Procedures, Surgical Staplers, Tissue Adhesives
- Trial name
- SPIRAL (NCT00925444)
- Testing
- FOREseal, Stapling
- Where
- France
- Volunteers
- 380 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris