Clinical trials: Alcohol Disorders
Alcohol Abuse, Alcohol Drinking
Tracking Mood: The Effects of Daily Mood Tracking VAS on Alcohol Consumption in Adult Heavy Drinkers
The study aims to investigate the effects that mood tracking may have on the alcohol consumption of adults who consume more than 20 UK units of alcohol per week, classifying as high-risk drinkers.
- Conditions
- Alcohol Abuse, Alcohol Drinking, Alcohol Use Disorder, Alcohol Dependence
- Trial name
- NCT06419647
- Testing
- Intervention
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Ilona Myllyniemi
Temporomandibular Disorder (TMD)
JIT: Effect of Pain on DT in TMD
Individuals with chronic temporomandibular disorder (TMD) pain are at increased risk for alcohol-related consequences compared to those without pain, and growing evidence suggests pain is a potent motivator for alcohol use in…
- Trial name
- TMD (NCT06659991)
- Testing
- alcohol condition, control condition
- Where
- United States
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Biofilms, Substantivity
Immediate Effect and Substantivity of the Essential Oils Without Alcohol on the Oral Biofilm in Situ
This study aims to evaluate the in situ antibacterial activity of a mouthwash containing essential oils with and without alcohol on undisturbed de novo plaque-like biofilm (PL-biofilm) up to 7 h after its application.
- Conditions
- Biofilms, Substantivity, Oils, Essential
- Trial name
- NCT02946814
- Testing
- essential oils, essential oils without mouthwash, sterile water
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Alcohol Dependence, Insomnia
Pharmacotherapy and Mechanisms of Sleep Disturbance in Alcohol Dependence
Insomnia and other sleep abnormalities are common, persistent, and associated with relapse in alcohol-dependent patients. The overall, long-term objectives of the proposed research are to investigate the neurophysiologic…
- Trial name
- MA (NCT01014533)
- Testing
- Gabapentin dispensed to subject.
- Where
- United States
- Volunteers
- 59 people, healthy volunteers welcome
- Sponsor
- Dr. Kirk Brower
Alcohol Use Disorder
Methylphenidate and Response to Alcohol Cues
The purpose of this study is to determine whether changes in attention levels related to taking a single dose of a medication called methylphenidate, also known as Ritalin, affects responses to alcohol cues.
- Trial name
- NCT07306078
- Testing
- Methylphenidate Pill
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Florida
Alcohol Concentration Values, Alcohol Intoxication
Manipulation of Breath Alcohol Tests: Can Specific Techniques Alter Blood Alcohol Concentration Readings?
This is a prospective cohort study. The investigators will enroll 50 healthy volunteers. In a safe environment and after signing informed consent, each participant will consume a standardized alcoholic beverage.
- Trial name
- NCT02580318
- Testing
- breathalyzer
- Where
- United States
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- St. Luke's Hospital and Health Network, Pennsylvania
Cardiovascular Disease, Alcohol Use Disorder
Mortality Reductions Based on AUD/Heavy Alcohol Use, HIV Risk, and Cardiovascular Risk
The purpose of this research study is to investigate if a personalized intervention including parts such as navigation (focus on patient outreach efforts, missed and completed encounters), personalization (individual health…
- Conditions
- Cardiovascular Disease, Alcohol Use Disorder, HIV Risk, Substance Use Disorders
- Trial name
- NCT05828849
- Testing
- Navigation, compensation, and personalization
- Where
- United States
- Volunteers
- 87 people, healthy volunteers welcome
- Sponsor
- NYU Langone Health
Alcohol Use Disorder, Depression
Project VALOR: Veteran Stress and Wellbeing
This study will examine the efficacy of an internet-based brief intervention designed to reduce risky behavior veterans as the move into their second year post-Army.
- Trial name
- NCT06095817
- Testing
- Internet Delivered Brief Intervention (IDBI)
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Cornell University
Alcohol Related Disorders, Substance Related Disorders
The Co-Venture Trial: A Cluster Randomized Trial of Personality-targeted Interventions on Adolescent Substance Use and Cognitive Outcomes
The Preventure Program is the first and only school-based alcohol and drug prevention program that has been shown to prevent onset and growth in alcohol and substance misuse in British and Canadian youth.
- Trial name
- NCT01655615
- Testing
- Preventure programme
- Where
- Canada
- Volunteers
- 3,900 people, healthy volunteers welcome
- Sponsor
- St. Justine's Hospital
Breast Neoplasms
The Influence of Breast Cancer Risk and Risk Perception on Lifestyle Behaviors Among Women With a Family History: A Mixed Method Approach
Lifestyle behaviors among women with a family history of breast cancer are likely to be influenced by a number of factors, including both objective risk factors and subjective risk, or perceived risk.
- Trial name
- NCT00393406
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institute of Environmental Health Sciences (NIEHS)
Binge Drinking, Problematic AOD Use
Two Consecutive Randomized Controlled Trials Using Mobile Phone Applications for Risky Alcohol Use
The purpose of this study is to evaluate the efficacy of three mobile phone applications, Promillekoll, PartyPlanner and TeleCoach among university student union members with problematic drinking.
- Trial name
- NCT02064998
- Testing
- Promillekoll, PartyPlanner, TeleCoach
- Where
- Sweden
- Volunteers
- 2,166 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Stress Disorders, Post-Traumatic, Drinking Heavy
Project QueST 2023: Queer Survivors of Trauma
This study aims to test the initial efficacy of tailored online writing interventions specifically designed for sexual minority women, transgender individuals, and/or nonbinary people to target the primary outcomes: posttraumatic…
- Trial name
- QueST2023 (NCT05569915)
- Testing
- Trauma Expressive Writing, Stigma Expressive Writing, Control
- Where
- United States
- Volunteers
- 131 people, healthy volunteers welcome
- Sponsor
- Syracuse University
HIV-1-infection, Alcohol Drinking
Acute Neural and Immune Effects of Alcohol in People Living With HIV Infection
This study will examine whether moderate alcohol use in the context of HIV infection exacerbates inflammatory signaling in the immune system and brain.
- Trial name
- NCT04050735
- Testing
- Alcohol, ethyl, moderate dose
- Where
- United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Brown University
Essential Tremor, Tremor
Functional Imaging of Tremor Circuits and Mechanisms of Treatment Response
Essential Tremor (ET) is the most common tremor disorder, currently affecting an estimated 2.9 million Americans and leading to disability and decreased quality of life in 75% of cases.
- Trial name
- NCT02495883
- Testing
- Ethanol, Propranolol
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Alcoholism
Characterization of [11C]Flumazenil to Image GABA Transmission in Healthy Adult Subjects and Subjects With Alcohol Dependence
Background: This study is being done to examine the role of a chemical GABA in the brain of alcohol dependent patients. GABA is the chief inhibitory neurotransmitter in the central nervous system.
- Trial name
- NCT01904487
- Testing
- [11C]flumazenil, Tiagabine
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Rajesh Narendran
Alcohol-Related Disorders
Does Mixing Alcoholic Drinks Make Hangover Worse?
Does mixing alcohol make hangover worse?
- Trial name
- NCT03506516
- Testing
- Mixing alcohol, Single type alcohol
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Zealand University Hospital
Alcohol Drinking, Alcohol Abuse
Using Counter Attitudinal Advocacy to Change Drinking Behavior
High volume drinking by young adults has proven resistant to change, so new approaches are needed. We adapt a theory-based attitude change strategy for use in alcohol prevention.
- Trial name
- NCT04042909
- Testing
- Counter Attitudinal Advocacy, Personalized Normative Feedback
- Where
- 2 sites in United States
- Volunteers
- 591 people, healthy volunteers welcome
- Sponsor
- Brown University
Opioid-use Disorder, Alcohol Use Disorder
COVID-19-Related Opioid Treatment Policy Evaluation
Our nation is facing the COVID-19 pandemic during an ongoing opioid epidemic. Effective treatment for patients with opioid use problems involves a treatment method called Medication-Assisted Treatment, or MAT.
- Trial name
- COPE (NCT05028998)
- Where
- United States
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Boston VA Research Institute, Inc.
Opioid-Related Disorders, Substance-Related Disorders
Subjective/Psychomotor/ Effects of Combined Alcohol & Nitrous Oxide - 16
The purpose of this study is to examine the subjective, psychomotor, and reinforcing effects of combined alcohol and nitrous oxide intake in healthy volunteers.
- Trial name
- NCT00000264
- Testing
- 30% Nitrous oxide, 0.35 g/Kg ethanol, 0.7 g/Kg ethanol
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- University of Chicago
Type 1 Diabetes
Evaluation of iDECIDE: A Smartphone App for Insulin Dosing Accounting for Alcohol and Exercise
The investigators propose a randomized cross-over study Phase 1 Clinical trial. 30 type 1 diabetes adult outpatients using insulin pumps and continuous glucose monitoring system will be recruited from the Endocrinology Clinic at…
- Trial name
- NCT02835183
- Testing
- iDECIDE, Insulin pump
- Volunteers
- healthy volunteers welcome
- Sponsor
- Arizona State University