Clinical trials: Alcohol Problem
Postpartum Depression (PPD), Alcohol Use
Maternal Outcomes: Mood, Alcohol Use, and Depressive Symptoms
This study aims to learn about depression and alcohol use in postpartum mothers and whether an intervention based on contingency management and problem-solving therapy (CM-PST) can help reduce these symptoms.
- Conditions
- Postpartum Depression (PPD), Alcohol Use, Contingency Management, Problem Solving Therapy
- Trial name
- MOMS-AD (NCT07485036)
- Testing
- Contingency Management & Problem Solving Therapy, Usual Care
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- University of Illinois at Chicago
Sleep Disturbance, Sleep Problems
Transdiagnostic Sleep Intervention to Improve Mental Health in Adolescents
This cluster randomized controlled trial will evaluate whether a brief, school-based group adaptation of the Transdiagnostic Intervention for Sleep and Circadian Dysfunction (TranS-C) improves sleep and mental health in…
- Conditions
- Sleep Disturbance, Sleep Problems, Substance Use (Drugs, Alcohol), Anxiety
- Trial name
- SLEEP-TEEN (NCT07865728)
- Testing
- Transdiagnostic Intervention for Sleep and Circadian Dysfunction, Healthy habits psychoeducation
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Universidad Pública de Navarra
Heavy Episodic Drinking, Problem Drinking
Greek Connections Study
The purpose of this study is to evaluate the feasibility and acceptability of an intervention aiming to reduce heavy episodic drinking and negative consequences from alcohol by increasing the availability of and engagement in…
- Conditions
- Heavy Episodic Drinking, Problem Drinking, College Student Drinking
- Trial name
- NCT07839026
- Testing
- Alcohol-free Social Activities Program
- Where
- United States
- Volunteers
- 480 people, healthy volunteers welcome
- Sponsor
- University of Washington
Asperger's Disorder, Asperger Disorder
QAIAx (AIhealth4U) - AI Smart Health Cities: Microcity Enclave Program (Quantum AI/AGI Agency a/k/a AI City Hall Project - UPSTO App Nos. 64/074,526, 64/063,557, 64/105,164, 63/903,181, 63/729,428, 64/125,360)
BRIEF SUMMARY A. "What is the purpose of this study?" BACKGROUND. The QAIAx clinical trial (Quantum AI/AGI Public Health Agency), known operationally as the "AI City Hall Project," represents a landmark intergovernmental research…
- Conditions
- Asperger's Disorder, Asperger Disorder, Autism Disorder, Autism
- Trial name
- QAIAx (NCT07661823)
- Testing
- AI City Hall Project (AIhealth4u - Public Health Central), AI City Hall Project (QAIAx Microcity A - AI Public Health Central)
- Where
- United States
- Volunteers
- 1,000,000 people, healthy volunteers welcome
- Sponsor
- Veterans Recovery Network Inc.
Hiv, Alcohol Problem
Telemedicine for Unhealthy Alcohol Use in Persons Living With HIV Using CETA
This study is designed to examine the efficacy of an alcohol-focused brief intervention alone versus the brief intervention plus referral to a transdiagnostic cognitive-behavioral intervention to address unhealthy alcohol use and…
- Trial name
- TALC (NCT04955795)
- Testing
- Alcohol Brief Intervention (BI), Common Elements Treatment Approach (CETA) via Telemedicine
- Where
- United States
- Volunteers
- 308 people
- Sponsor
- University of Alabama at Birmingham
Posttraumatic Stress Symptom, Alcohol Drinking
Testing the Impact of Thrive App Versions on Alcohol Use and Posttraumatic Stress After Recent Sexual Assault
The goal of this study is to find the most effective and efficient version of the THRIVE app. The THRIVE app is the first app-based preventative intervention that has been found to reduce alcohol misuse and posttraumatic stress…
- Conditions
- Posttraumatic Stress Symptom, Alcohol Drinking, Alcohol Problem
- Trial name
- NCT06444295
- Testing
- Activity scheduling, Cognitive restructuring, Coaching calls
- Where
- United States
- Volunteers
- 464 people
- Sponsor
- University of Washington
Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms
Personalizing Treatment Delivery
Anxiety and anxiety-related disorders frequently co-occur with alcohol use problems resulting in an enormous humanitarian and economic cost to society.
- Conditions
- Anxiety Disorders and Symptoms, PTSD and Trauma-related Symptoms, Alcohol; Use, Problem; Alcohol Use Disorder
- Trial name
- NCT05821634
- Testing
- Personalized intervention condition: Cognitive behavioral therapy skills, Therapeutic control condition: Cognitive behavioral therapy skills, Tracking control condition: Supportive counseling
- Where
- United States
- Volunteers
- 81 people
- Sponsor
- Rutgers, The State University of New Jersey
Alcohol Problem
Game-Based Intervention to Reduce Alcohol Use Among Youth
This is a randomized controlled trial to learn if the Singularities, a game-based intervention, works to reduce alcohol-related harms among youth.
- Trial name
- NCT07463118
- Testing
- Food4Thought, Singularities
- Where
- United States
- Volunteers
- 1,992 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
PTSD, Alcohol; Use, Problem
Evaluating Signs of Safety: A Deaf-Accessible Therapy Toolkit for AUD and Trauma
The U.S. Deaf community - a group of more than one million Americans who communicate using American Sign Language (ASL) - experiences nearly triple the rate of lifetime problem drinking and twice the rate of trauma exposure…
- Trial name
- NCT06278922
- Testing
- Seeking Safety + Signs of Safety toolkit, Treatment as usual
- Where
- United States
- Volunteers
- 144 people
- Sponsor
- University of Massachusetts, Worcester
Alcohol Drinking, Binge Drinking
Reducing Blood Pressure in Mid-life Adult Binge Drinkers
This study has two phases: Phase 1 is to examine blood pressure, microvascular function, and sympathetic nerve activity in mid-life adult binge drinkers vs. alcohol abstainers/moderate drinkers.
- Conditions
- Alcohol Drinking, Binge Drinking, Blood Pressure, Alcohol Abstinence
- Trial name
- NCT05522075
- Testing
- Exercise Training, Alcohol Abstinence Intervention
- Where
- United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Arlington
Alcohol; Use, Problem, Posttraumatic Stress Disorder
Understanding and Testing Recovery Processes for PTSD and Alcohol Use Following Sexual Assault
Sexual assault can lead to devastating consequences including the development of chronic conditions including posttraumatic stress disorder (PTSD) and alcohol use disorders (AUD).
- Trial name
- NCT04124380
- Testing
- Imaginal Exposure, Alcohol Skills Training, Supportive Telehealth
- Where
- United States
- Volunteers
- 82 people
- Sponsor
- University of Washington
Alcohol; Use, Problem, Stress
A Behavioral Activation Intervention Administered in a College Freshman Orientation Course
The transition from high school to college is a developmentally sensitive period that is high risk for escalations in alcohol use.
- Conditions
- Alcohol; Use, Problem, Stress, Binge Eating, Depression
- Trial name
- NCT04038190
- Testing
- behavioral activation
- Where
- United States
- Volunteers
- 572 people, healthy volunteers welcome
- Sponsor
- University of Kansas
Alcohol Misuse, Alcohol Use Disorder
Exploration of Acceptability of Alcohol Interventions
This is a mixed-methods study consisting of a qualitative assessment the acceptability of psychosocial interventions, delivered by clinical staff.
- Conditions
- Alcohol Misuse, Alcohol Use Disorder, Behaviour Change, Health Behaviour
- Trial name
- NCT07580378
- Where
- United Kingdom
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- East Lancashire Hospitals NHS Trust
Alcohol; Use, Problem
Using EMA Data to Inform a Web-intervention for Couples Concerned About Drinking
Alcohol misuse is a prevalent and serious problem with significant harms to society, individuals, and their relationships. Romantic partners have a strong influence on their partner's behavior, uniquely positioning them as a…
- Trial name
- NCT06501677
- Testing
- WBI
- Where
- United States
- Volunteers
- 275 people, healthy volunteers welcome
- Sponsor
- Stanford University
Healthy Volunteers, Alcohol Drinking Related Problems
A Response Modulation Hypothesis of Socioemotional Processing Associated With Alcohol Use Disorder
Background: Problem drinking affects nearly half the people who drink alcohol. Drinking alcohol affects a person's social behavior and brain structure, but researchers don't have a good understanding of how.
- Conditions
- Healthy Volunteers, Alcohol Drinking Related Problems, Alcohol-Related Disorders
- Trial name
- NCT03535129
- Testing
- Real time fMRI neurofeedback
- Where
- United States
- Volunteers
- 101 people
- Sponsor
- National Institutes of Health Clinical Center (CC)
Alcohol Problem, Harm Reduction
Game-Based Intervention to Reduce Alcohol-Related Harms Among Sexual and Gender Minority Youth
This is a randomized controlled trial to examine the efficacy of a game-based intervention to reduce alcohol-related harms among sexual and gender minority youth.
- Conditions
- Alcohol Problem, Harm Reduction, Alcohol-Related Harm
- Trial name
- NCT06215664
- Testing
- Singularities Game, Food4Thought
- Where
- United States
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Pittsburgh
Alcohol Problems, Post-Traumatic Stress Disorder
The Development of a Transdiagnostic Intervention to Improve Social Functioning and Intimate Relationships Among Veterans
Veterans seeking to improve their romantic relationships when high conflict and unhealthy dynamics (e.g., aggression) are present remain underserved within the VHA with few treatment options.
- Trial name
- ACT-SHARE (NCT06746727)
- Testing
- Acceptance and Commitment Therapy for Social Health, Achievement, and Relationship Effectiveness (ACT-SHARE)
- Where
- United States
- Volunteers
- 29 people
- Sponsor
- VA Office of Research and Development
Alcohol Use Disorder, Alcohol Abuse
Developing Functional Connectivity-Guided TMS for Alcohol Use Disorder
Alcohol Use Disorders are currently positioned as the third leading cause of preventable death in the United States, constituting a humanitarian crisis with substantial financial burden on society and medical facilities.
- Conditions
- Alcohol Use Disorder, Alcohol Abuse, Alcoholism, Drinking Behavior
- Trial name
- NCT06415721
- Testing
- Active Transcranial Magnetic Simulation
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- VA Palo Alto Health Care System
Alcohol Drinking, Alcohol Drinking Related Problems
Efficacy of Leuconostoc Mesenteroides
Excessive alcohol intake can cause dehydration, digestive issues, oxidative stress, and hangover symptoms like headache and fatigue. Toxic metabolites like acetaldehyde and ROS contribute to liver damage.
- Trial name
- NCT07017088
- Testing
- Leuconostoc mesenteroides
- Where
- South Korea
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- Wonju Severance Christian Hospital
Fetal Alcohol Spectrum Disorders, Behavior Problem
Psychoeducation of Parents to Children With FASD
By longitudinal, prospective research in children and adolescents with Fetal Alcohol Spectrum Disorders (FASD) and their parents to explore the beneficial effects of participating in a standardized intervention program in order…
- Conditions
- Fetal Alcohol Spectrum Disorders, Behavior Problem, Adaptive Behavior, Learning Disorders
- Trial name
- NorFASDPEdu (NCT05686473)
- Testing
- Program of psychoeducation of parents and professionals
- Where
- Norway
- Volunteers
- 75 people
- Sponsor
- Sorlandet Hospital HF