Clinical trials: Allergic Rhinitis Due to Grass Pollen
Allergic Rhinitis Due to Grass Pollen
The Influence of Nonspecific Immunostimulation on Changes in the Concentration of iNKT Cells
The aim of the study is to assess the effect of polyvalent mechanical bacterial lysate (PMBL, Ismigen) on the clinical course of grass pollen-induced allergic rhinitis (using: total nasal symptom score, visual analogue scale…
- Trial name
- NCT04802616
- Testing
- Ismigen
- Where
- Poland
- Volunteers
- 80 people
- Sponsor
- Medical University of Lublin
Allergic Rhinitis Due to Grass Pollen
Intralymphatic Immunotherapy Enhanced by Vitamin-D, a Randomized Placebo-controlled Trial and Comparison With SLIT
A national, multicenter, randmised double blind study with parallell arms. 360 patients with grass induced allergic rhinitis will be open randomised 1:2 to 3 years Grazax sublingual immunotherapy or 3 intralymphatic injections…
- Trial name
- ILIT vs SLIT (NCT06061848)
- Testing
- SLIT Grazax ALK Nordic 75 000 SQ-T, ILIT + Vitamin D
- Where
- 3 sites in Sweden
- Volunteers
- 360 people
- Sponsor
- Lars Olaf Cardell
Allergic Rhinitis Due to Grass Pollen
ILIT: Follow-up of Rhinitis Quality of Life
Re-evaluation of patients treated with intralymphatic immunotherapy (ILIT) in terms of quality of life and therapeutic efficacy and comparison with subcutaneous immunotherapy (SCIT) 15 years post immunotherapy
- Trial name
- NCT05037955
- Where
- Switzerland
- Volunteers
- 162 people
- Sponsor
- University of Zurich
Seasonal Allergic Rhinitis
POPULAR (Preference Of Patient Using Levocetirizine in Allergic Rhinitis)
Comparative study on clinical efficacy and safety of levocetirizine and desloratadine as measured by the subject's satisfaction/dissatisfaction after one week of treatment
- Trial name
- NCT00160537
- Testing
- Levocetirizine
- Volunteers
- 200 people
- Sponsor
- UCB Pharma
Allergic Asthma, Thunderstorm Asthma
Creating A Risk Assessment Tool for Thunderstorm Asthma: the CARISTA Study
Thunderstorm asthma is a recurring public health emergency in South-Eastern Australia which occurs in springtime. The major identified risk factors for thunderstorm asthma is hay fever and allergy to ryegrass pollen.
- Conditions
- Allergic Asthma, Thunderstorm Asthma, Seasonal Allergic Rhinitis, Grass Pollen Allergy
- Trial name
- CARISTA (NCT07055542)
- Testing
- Observational
- Where
- 6 sites in Australia
- Volunteers
- 530 people, healthy volunteers welcome
- Sponsor
- University of Melbourne
Seasonal Allergic Rhinitis
A Study of Tolerability and Safety of a New Cumulative Dose of Grass MATA MPL
There is increasing evidence that the effectiveness of allergy immunotherapy to control symptoms of rhinoconjunctivitis is related to the cumulative dose of allergen or allergoid administered during a single regimen of…
- Trial name
- G104 (NCT03931993)
- Testing
- Grass MATA MPL
- Where
- 4 sites in United States
- Volunteers
- 30 people
- Sponsor
- Allergy Therapeutics
Allergic Rhinitis, Allergic Rhinitis Due to Grass Pollen
Study to Assess the Safety, Tolerability, and Preliminary Efficacy of B244 in Healthy Volunteers and Subjects With Seasonal Allergic Rhinitis
This is a Prospective, Controlled, Double Blinded, Single Center, Randomized, 3 Arm, Parallel Assignment, Phase 1b/2a Study to assess the safety, tolerability, and preliminary efficacy of B244 delivered as an intranasal spray in…
- Conditions
- Allergic Rhinitis, Allergic Rhinitis Due to Grass Pollen, Healthy Volunteers
- Trial name
- NCT03290248
- Testing
- B244 suspension, Vehicle
- Where
- 2 sites in United States, Canada
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- AOBiome LLC
Allergic Rhinitis Due to Grass Pollens
International Registry on the Quality of Life of Patients With Grass-pollen-induced Allergic Rhinitis
The purpose of the present study is to describe patient's perception of quality of life and effectiveness of ORALAIR® over a follow-up period up to 5 years, in real-life settings.
- Trial name
- ALTO (NCT02041624)
- Where
- France
- Volunteers
- 740 people
- Sponsor
- Stallergenes Greer
Rhinitis, Allergic, Seasonal, Rhinitis; Allergic, With Asthma
Intralymphatic Immunotherapy With Polvac Grass & Rye Allergen Extract
The primary goal is to investigate the efficacy of intralymphatic immunotherapy (ILIT) for the treatment of allergic rhinitis and allergic asthma due to sensitisation to grass pollen allergens.
- Conditions
- Rhinitis, Allergic, Seasonal, Rhinitis; Allergic, With Asthma, Allergic Rhinitis, Allergic Rhinitis Due to Grass Pollen
- Trial name
- NCT05297760
- Testing
- Polvac Grass+Rye, Saline 0.9%
- Where
- Switzerland
- Volunteers
- 60 people
- Sponsor
- University of Zurich
Allergic Rhinoconjunctivitis
Changes in Specific Immunoglobulin and Blood Basophil Activity During Subcutaneous Immunotherapy in Allergic Rhinitis
The trial is randomized prospective study to examine the effects of subcutaneous immunotherapy on the adaptive immune system. The trial includes 30 participants randomized to treatment or control group.
- Trial name
- NCT01085526
- Testing
- Alutard phleum pratense subcutaneous immunotherapy, Alutard phl prat
- Volunteers
- 30 people
- Sponsor
- Aarhus University Hospital
Allergic Rhinitis Due to Grass Pollens
Study of Efficacy and Safety of 300 IR Sublingual Immunotherapy (SLIT) Tablets in Adult Patients With Allergic Grass Pollen Rhinoconjunctivitis
The purpose of the study is to assess the efficacy and safety of 300 IR sublingual tablet of grass pollen allergen extract compared to placebo in adult patient with allergic rhinoconjunctivitis.
- Trial name
- NCT00955825
- Testing
- 300 IR
- Where
- 19 sites in United States
- Volunteers
- 473 people
- Sponsor
- Stallergenes Greer
Allergic Rhinitis Due to Grass Pollen, Allergic Asthma
Kinetics of Nasal Cytokine Responses to Mechanical Stimulation
IgE-associated allergy is a hypersensitivity disease affecting more than 40% of the population in industrialised countries. Recently the kinetics of change of clinical and immunological parameters (e.g.
- Trial name
- NCT04878237
- Testing
- Nasal Secretion Sampling
- Where
- Austria
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Allergic Rhinitis
Efficacy and Tolerability of a Topical Microemulsion in Patients With Allergic Rhinitis Due to Sensitization to Pollen
Study design: Randomized, controlled, double-blind, parallel, multicentre multinational clinical trial, to show superiority of an active therapy as compared to a control therapy on intermittent or persistent Allergic Rhinitis.
- Trial name
- NCT01478425
- Testing
- Lipidic Microemulsion, Saline
- Where
- 9 sites in Spain, Sweden
- Volunteers
- 110 people
- Sponsor
- Reig Jofre Group
Allergic Rhinitis Due to Grass Pollen, Allergic Conjunctivitis of Both Eyes
Documentation of Efficacy of Intralymphatic Allergen Immunotherapy
Investigation of the clinical efficacy of 3 intralymphatic injections with grass pollen extract into inguinal lymph nodes on combined symptom-medication scores during grass pollen season in grass pollen allergic patients compared…
- Conditions
- Allergic Rhinitis Due to Grass Pollen, Allergic Conjunctivitis of Both Eyes, Allergic Asthma
- Trial name
- ILITNU (NCT05191186)
- Testing
- Grass pollen extract - Alutard Phleum pratense, ALK
- Where
- 2 sites in Denmark, Sweden
- Volunteers
- 450 people
- Sponsor
- Aarhus University Hospital
Allergic Rhinitis
A Study of Tolerability and Safety of Two New Doses of Grass MATA MPL
There is increasing evidence that the effectiveness of allergy immunotherapy to control symptoms of rhinoconjunctivitis is related to the cumulative dose of allergen or allergoid administered during a single regimen of…
- Trial name
- NCT02557633
- Testing
- Grass MATA MPL 10200, Grass MATA MPL 18200
- Where
- 2 sites in United States
- Volunteers
- 29 people
- Sponsor
- Allergy Therapeutics
Allergic Rhinitis Due to Grass Pollens
Molecular and Cellular Mechanism in the Course of Immunotherapy With a Phleum Pratense Oral Lyophilisate
This trial is an exploratory randomised, parallel-group, double-blind, placebo- controlled, national, single-centre trial. The trial will be initiated before 2013 grass pollen season and subjects will be randomised in September…
- Trial name
- NCT01854736
- Testing
- Grazax
- Where
- 2 sites in Spain
- Volunteers
- 51 people
- Sponsor
- ALK-Abelló A/S
Allergic Rhinitis Due to Grass Pollen, Allergic Inflammation
Efficacy of Puressentiel Protective Nasal Spray in Allergic Rhinitis
This study is a proof o concept aiming to determine the efficacy of Puressentiel nasal protective spray (PNPS) in patients with allergic rhinitis.
- Trial name
- EPPNS (NCT04700852)
- Testing
- Puressentiel protective nasal spray
- Volunteers
- 15 people
- Sponsor
- Puressentiel
Allergic Rhinitis Due to Pollen, Allergic Conjunctivitis
Tyrosine Allergoid Paediatric and Adult Study
The primary objective of this 5-year study is to demonstrate non-inferiority of children compared to adults by exploring long-term effectiveness after treatment with TA Bäume (trees) and TA Gräser (grass) following a perennial…
- Conditions
- Allergic Rhinitis Due to Pollen, Allergic Conjunctivitis, Allergic Asthma
- Trial name
- NCT05186025
- Testing
- MATA trees or MATA grass
- Where
- Germany
- Volunteers
- 320 people
- Sponsor
- Allergy Therapeutics
Allergic Rhinitis Due to Grass Pollens
M-Gard Particulate EW Efficacy Study on Seasonal Allergic Rhinitis
The goal of this clinical trial is to assess the efficacy and safety of M-Gard supplementation for alleviating the symptoms of allergic rhinitis.
- Trial name
- NCT06907680
- Testing
- M-Gard
- Where
- Australia
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- RDC Clinical Pty Ltd
Allergic Rhinitis Due to Grass Pollens
Immunological Comparison of AIT and SCIT Immunotherapy Against Grass Pollen
Treatment of pollen allergies can be roughly divided into symptomatic treatment (e.g. antihistamines, steroids) and potentially curative immunotherapy.
- Trial name
- NCT01889875
- Testing
- ALK Grazax 75,000 SQ-T "Phleum pratense", ALK AluTard 225 "Phleum pratense"
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Bispebjerg Hospital