Clinical trials: Alteration of Cognitive Function
Cognitive Change, Development, Adolescent
Enhancement of Learning and Memory Following Supplementation With Juice PLUS+® OMEGA in an Adolescent Population
This study aims to investigate the effect of chronic supplementation with a commercially available, plant-derived, omega-3 intervention and cognitive performance in adolescent participants aged 13-14 years.
- Trial name
- AdCog-O (NCT05581108)
- Testing
- Juice PLUS+® OMEGA
- Where
- United Kingdom
- Volunteers
- 66 people, healthy volunteers welcome
- Sponsor
- University of Reading
Prosthesis User, Cognitive Change
Evaluation of a Novel Bionic Foot, AMPfoot 4+
Background: Evaluating the use of a novel motorized ankle prosthesis during walking and under dual task circumstances is an important step in product development.
- Conditions
- Prosthesis User, Cognitive Change, Physical Activity
- Trial name
- NCT03530956
- Testing
- Ankle Mimicking Prosthetic Foot prototype 4+
- Where
- Belgium
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- Vrije Universiteit Brussel
Cognitive Change
CMI-168 on Cognitive Function in Healthy Middle-aged Men and Women
The investigators propose to conduct the present study in order to primarily assess the effects of CMI-168 in neurocognition enhancement.
- Trial name
- NCT03612752
- Testing
- CMI-168
- Where
- Taiwan
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Cerebos Pacific Limited
Cognitive Change
Effects of Seaweed Extract on Mental Performance Following a High-carbohydrate Meal
The current study will explore the impact of seaweed extract on cognitive function following a high-carbohydrate meal at a number of time-points post-consumption.
- Trial name
- NCT03328923
- Testing
- 500mg brown seaweed powder
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Northumbria University
Memory Loss, Cognitive Changes
Aging and Estrogen on Cortical Function
This study will focus on how estrogen affects parts of the brain associated with memory and how the effect of estrogen is altered with aging in postmenopausal women.
- Conditions
- Memory Loss, Cognitive Changes, Postmenopausal Symptoms
- Trial name
- NCT01268046
- Testing
- Estradiol oral capsule, transderman estrogen patch
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Cognitive Wellness, Healthy Aging
MEVA Cognitive Wellness Platform Study for Adults
The goal of this observational study is to evaluate the reliability, usability, and feasibility of the MEVA Cognitive Wellness Platform in community-dwelling adults aged 55 to 75.
- Conditions
- Cognitive Wellness, Healthy Aging, Age-Related Cognitive Change, Aging
- Trial name
- MEVA (NCT07595250)
- Testing
- MEVA Cognitive Wellness Platform
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mentage LLC
Cognitive Change
An Open-label, Exploratory Study to Investigate the Efficacy of BDNF Essentials® on Cognition
The objective of this open-label, exploratory study is to investigate the efficacy of BDNF Essentials® on cognition in a healthy adult population with self-reported memory complaints.
- Trial name
- NCT04860778
- Testing
- BDNF Essentials
- Where
- Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Researched Nutritionals LLC
Cognitive Change
Mindfulness Training for Small Teams
The purpose of this study is to look at how mindfulness training may influence how the participant thinks, feels, and acts.
- Trial name
- NCT04210076
- Testing
- MBAT-T, MBAT-I
- Where
- United States
- Volunteers
- 356 people, healthy volunteers welcome
- Sponsor
- University of Miami
Age-Related Macular Degeneration
Brain Connectivity in Age-Related Macular Degeneration
This study is to determine how cognitive deficits (e.g.,verbal fluency deficit) in patients with Age-Related Macular Degeneration (AMD) relate to specific aspects of brain and function.
- Trial name
- NCT01996215
- Where
- United States
- Volunteers
- 238 people, healthy volunteers welcome
- Sponsor
- Duke University
Healthy Aging, Cognitive Change
The Effect of Transcranial Direct Current Stimulation on Visual Attention - Single Sessions
Recently, attention has been drawn to non-invasive brain stimulation techniques, such as transcranial direct current stimulation (tDCS), in order to enhance cognitive functions by modifying brain plasticity and use it in…
- Conditions
- Healthy Aging, Cognitive Change, Cognitive Decline
- Trial name
- NCT04134195
- Testing
- Transcranial direct current stimulation
- Where
- Czechia
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Masaryk University
Cognitive Change, Stress
Vitamin (VIT) for Vigilance Study
This study aims to examine the effects of a 6-week colon-delivered multi-vitamin supplement intervention on cognitive performance and stress levels in military under real-life, stressful working conditions.
- Trial name
- NCT05574530
- Testing
- Colon-delivered multivitamin supplement
- Where
- Netherlands
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Wageningen University and Research
Attention Impaired, Cognitive Change
The Influence of Mindfulness Meditation Retreat on Attention to Internal Experience
Although attention is thought to have a definitive functional role in mindfulness meditation training and its salutary mechanisms of action, extant empirical evidence is mixed and limited.
- Conditions
- Attention Impaired, Cognitive Change, Mental Health Issue
- Trial name
- NCT04749264
- Testing
- Mindfulness meditation retreat
- Where
- Israel
- Volunteers
- 142 people, healthy volunteers welcome
- Sponsor
- University of Haifa
Mild Cognitive Impairment
Brain and Cognitive Changes After Reasoning Training in Individuals With Mild Cognitive Impairment
Individuals aged 55 and older may experience negative effects of cognitive decline. The proposed research seeks to evaluate the benefits of different types of interventions: reasoning training following transcranial direct…
- Trial name
- NCT02596906
- Testing
- tDCS
- Where
- United States
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- The University of Texas at Dallas
Cognitive Change
Measuring Mindfulness Application
The purpose of the research study is to learn more about how ROTC cadets may engage with mindfulness training program content that is delivered through a smartphone or website application.
- Trial name
- NCT04589195
- Testing
- Mindfulness Training
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Miami
Cognitive Change
Effectiveness of Cognitive Training in Older and Younger Adults
The proposed study will enroll 1600 participants to examine the effectiveness of cognitive training. Participants will be randomized into different experimental groups and can expect to participate for up to 15 hours of research…
- Trial name
- NCT06375681
- Testing
- Visual and / or Auditory Cognitive Tasks (1), Visual and / or Auditory Cognitive Tasks (2)
- Where
- 3 sites in United States
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Pre Diabetes, Vascular Stiffness
Dietary Exchanges With Avocado and Mango in Pre-diabetes
The research is designed as a randomized, 2-arm, parallel, controlled, human clinical trial to investigate the effects of avocado and mango consumption for 8 weeks on indices of macro- and micro- vascular function in individuals…
- Conditions
- Pre Diabetes, Vascular Stiffness, Vascular Dilation, Cognitive Change
- Trial name
- AVMa (NCT05353790)
- Testing
- Meals + snacks: control, Meals + snacks: Avocado mango
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Clinical Nutrition Research Center, Illinois Institute of Technology
Cognitive Change, Atrophy Brain
Physiologic Volume and Atrophy of Brain and Spinal Cord Measured by Magnetic Resonance Imaging
Spinal cord (SC) involvement is prevalent in multiple sclerosis (MS) and contributes importantly to disease progression. To be able reliably evaluate spinal cord volume and its changes in MS patients we need to understand…
- Conditions
- Cognitive Change, Atrophy Brain, Atrophy; Spinal Cord, Multiple Sclerosis
- Trial name
- NCT03706118
- Testing
- Magnetic resonance imaging
- Where
- Czechia
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Dana Horakova
Cognitive Change, Child Development
Conectar Jugando: Board Games in Rural Elementary Classrooms (6-12 Years Old) to Improve Executive Functions
The use of board games in classrooms has been increasing in recent years. Education and psychology professionals have found in the board game a way to train some key cognitive processes for good academic development: executive…
- Trial name
- CJ-Rural (NCT05267730)
- Testing
- Conectar Jugando Game Program
- Where
- Spain
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Brain In Game scientific-technical service
Randomized Controlled Trial, Occupational Therapy
Cognitive Stimulation Program in Elderly
The participants who carry out our cognitive stimulation program maintain and / or improve their score of the 35-point Spanish version of 35 points of Mini-mental State of Folstein; Mini-exam Cognoscitive of Lobo
- Conditions
- Randomized Controlled Trial, Occupational Therapy, Aging, Cognitive Change
- Trial name
- NCT04648670
- Testing
- Cognitive stimulation
- Volunteers
- 201 people, healthy volunteers welcome
- Sponsor
- Universidad de Zaragoza
Cognitive Change, Physical Performance
Coginitve and Physical Functions in Geriatric İndividuals
The aim of this study is to investigate the relationship between cognitive functions with physical performance, grip strength, walking speed, mobility, and frailty in geriatric individuals.
- Conditions
- Cognitive Change, Physical Performance, Frailty, Mobility
- Trial name
- NCT06400134
- Testing
- Cognitive Function, Physical Performance, Grip Strength
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Ankara Yildirim Beyazıt University