Clinical trials: Aminoglycoside Toxicity
Febrile Neutropenia (FN)
Probability of Optimal Target Attainment of Amikacin in Patients With Febrile Neutropenia During Treatment for a Hematological Disorder
The present trial is a single center, prospective, observational pharmacokinetics and pharmacodynamics (PKPD) cohort study investigating whether patients suffering from a hematological disorder and treated with amikacin due to…
- Trial name
- NCT05689450
- Testing
- Data collection: Amikacin concentration
- Where
- Switzerland
- Volunteers
- 92 people
- Sponsor
- University Hospital, Basel, Switzerland
Aminoglycoside Toxicity, Acute Kidney Injury
Risk Factors and Machine Learning Model for Aminoglycines Related Acute Kidney Injury
Drug-induced acute kidney injury (D-AKI) can occur after treatment with aminoglycosides. Predicting the risk of D-AKI is important for a tailored prevention and palliation strategy.
- Trial name
- NCT05533593
- Testing
- Aminoglycoside
- Where
- China
- Volunteers
- 8,000 people
- Sponsor
- Qianfoshan Hospital
Sepsis, Septic Shock
Aminoglycoside Administration in Septic Patients
Sepsis is one of the main causes of mortality and morbidity in an ICU setting, while the responsible microorganisms most frequently isolated are multidrug-resistant gram-negative bacteria.
- Conditions
- Sepsis, Septic Shock, Aminoglycoside Toxicity, Renal Replacement Therapy
- Trial name
- AMASEP (NCT06226441)
- Testing
- Continuous Renal Replacement Therapy
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- University of Thessaly
Aminoglycoside Toxicity, Aminoglycoside-Induced Hearing Loss
Video Game Hearing Tests for Remote Monitoring of Ototoxicity
The reason for this clinical trial is to test different ways of carrying out hearing tests to be able to detect for hearing loss within the hospital and at home.
- Conditions
- Aminoglycoside Toxicity, Aminoglycoside-Induced Hearing Loss, Hearing Loss, Video Games
- Trial name
- VAROT (NCT05847556)
- Testing
- video game hearing tests, Audio-training
- Where
- 2 sites in United Kingdom
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Bilateral Vestibular Hypofunction, Bilateral Vestibular Deficiency
Long Term Outcomes After Vestibular Implantation
Although cochlear implants can restore hearing to individuals who have lost cochlear hair cell function, there is no widely available, adequately effective treatment for individuals suffering chronic imbalance, postural…
- Conditions
- Bilateral Vestibular Hypofunction, Bilateral Vestibular Deficiency, Bilateral Vestibulopathy, Gentamicin Ototoxicity
- Trial name
- NCT06500975
- Testing
- Labyrinth Devices MVI™ Multichannel Vestibular Implant System
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- Johns Hopkins University