Clinical trials: Anesthesia, Conduction
Anesthesia, Local, Nerve Block
Lateral Sagittal vs Costoclavicular Approach for Ultrasound-Guided Infraclavicular Block
An ultrasound-guided infraclavicular block performed with the costoclavicular (CC) approach and the lateral sagittal (LS) approach will be compared in patients scheduled for forearm and hand surgery.
- Conditions
- Anesthesia, Local, Nerve Block, Brachial Plexus Block
- Trial name
- NCT04356521
- Testing
- Lateral Sagittal Approach, Costoclavicular Approach
- Where
- Turkey (Türkiye)
- Volunteers
- 109 people, healthy volunteers welcome
- Sponsor
- Ondokuz Mayıs University
Regional Anesthesia Morbidity, Hip Surgeries
Pericapsular Nerve Group Block vs. Fascia Iliaca Compartment Block vs. Caudal Block for Hip Surgeries
The study aims to compare the effect of pericapsular nerve group block versus fascia iliaca compartment block versus caudal block regarding Postoperative analgesia in children undergoing hip surgeries.
- Conditions
- Regional Anesthesia Morbidity, Hip Surgeries, Perioperative Analgesia
- Trial name
- NCT07137962
- Testing
- PENG Block, FICB Block, Caudal Block
- Where
- Egypt
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Cairo University
Post Operative Pain, Distal Radius Fracture
Low Dose Dexamethasone for Distal Radius Fractures
The addition of the steroid dexamethasone to a single injection of local anesthetic has been shown to significantly prolong the duration of peripheral nerve blockade compared to local anesthetic alone.
- Trial name
- NCT05274113
- Testing
- Dexamethasone 4mg, Ropivacaine
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Breast Cancer, Post Operative Pain
Dexmedetomidine Versus Dexamethasone as Adjuncts in Erector Spinae Plane Block in Modified Radical Mastectomy
The aim of this study is to evaluate the analgesic efficacy and safety of adding dexmedetomidine versus dexamethasone to levobupivacaine in ultrasound guided ESPB for patients undergoing modified radical mastectomy
- Trial name
- NCT05447949
- Testing
- Adjuncts to levobupivacaine in Erector Spinae Plane Block
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- National Cancer Institute, Egypt
Regional Anesthesia, Pain
Nociception Index Level (NOL) Perioperative Monitoring During Regional Anesthesia
This prospective observational study was conducted to assess pain using NOL index under locoregional anesthesia for orthopedic surgery of the upper limb.
- Conditions
- Regional Anesthesia, Pain, Intraoperative Monitoring
- Trial name
- NOL and LRA (NCT06300606)
- Testing
- NOL monitoring
- Where
- France
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- American Hospital of Paris
Postoperative Pain
Effect of Psychosocial and Psychophysical Factors and Preemptive Analgesia on Postoperative Pain in Upper Limb Surgery
The purpose of this study is to define the role of preemptive systemic analgesia in combination with regional anesthetic techniques on postoperative pain following upper limb surgery in different subgroups of patients with…
- Trial name
- NCT05248152
- Testing
- Paracetamol and Ibuprofen, Pregabalin 150mg
- Where
- Slovenia
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University Medical Centre Ljubljana
Thoracic Surgical Procedures
Erector Spinae Plane vs. Paravertebral Nerve Block for Thoracic Surgery
Continuous paravertebral analgesia and erector spinae plane blockade (ESP) are accepted techniques at University of Pittsburgh Medical Center (UPMC) for the management of thoracic pain following surgery and trauma.
- Trial name
- NCT03758261
- Testing
- Paravertebral nerve block, Erector Spinae nerve block
- Where
- United States
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Charles Luke
Obstetric Pain, Pain
Virtual Reality in Obstetric Patients
The purpose of this study is to determine if non-invasive distracting devices (Virtual Reality headset) are more effective than the standard of care (i.e., no technology based distraction) for preventing anxiety and pain scores…
- Trial name
- NCT03495531
- Testing
- Virtual Reality
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Stanford University
Male Circumcision, Regional Anesthesia
Pudendal Nerve Block vs Penile Nerve Block for Analgesia During Pediatric Circumcision
Pediatric circumcision has been realized since the beginning of human civilization. In the United States, a 2014 review revealed a 81% prevalence of men 14-59 years old being circumcised.
- Trial name
- NCT03914365
- Testing
- Ultrasound-guided pudendal nerve block (PNB) and Ultrasound-guided penile nerve block (DPNB)
- Where
- Canada
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Catastrophizing Pain
Personalizing Preprocedural Sedation for Regional Anesthesia
This is a prospective, randomized study in patients who receive a nerve block prior to surgery. The aim is to investigate whether individual differences in psychosocial and pain profiles may play a role in how patients experience…
- Trial name
- NCT05579509
- Testing
- Midazolam and Fentanyl, Educational Reassurance
- Where
- United States
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Transversus Abdominis Plane Block
Plasma Concentrations of Levobupivacaine With and Without Epinephrine in Transversus Abdominis Plane Blocks
The aim of this study is to determine the effect of the addition of vasoconstrictor in the plasma concentrations achieved and the extent of the transversus abdominis plane block in healthy male volunteers.
- Trial name
- NCT01596998
- Testing
- Levobupivacaine with epinephrine, Levobupivacaine without epinephrine, Monitoring
- Where
- Chile
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Pontificia Universidad Catolica de Chile
Propofol Injection Pain
Comparison of Bier Block and Lidocaine-Propofol Mixture for Prevention of Propofol Injection Pain
The goal of this clinical trial was to evaluate methods to prevent pain on intravenous administration of propofol during induction of anesthesia.
- Trial name
- BBLP (NCT07285980)
- Testing
- propofol, Lidocaine - Propofol Mixture, Lidocaine - Bier Block
- Where
- Tunisia
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Asma Ladib
Regional Anesthesia
Evaluation of a New Training Model for Ultrasound Guided Regional Anesthesia - A Feasibility Study
The use of Ultrasound Guided Regional Anaesthesia (USRA) has increased over the last decade. Theoretically, ultrasound imaging may increase efficacy and safety by allowing visualization of the needle pathway and local anaesthetic…
- Trial name
- NCT02370472
- Testing
- tool developed using cameras and a computer
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Pain, Postoperative, Anesthesia; Regional
The Pectoral Block for Breast Augmentation Surgery
The pectoral block is a recently developed regional anesthetic technique that can be used for the treatment of postoperative pain after breast surgery.
- Trial name
- BPCAM (NCT03040167)
- Testing
- PEC 1 block, Bupivacaine with epinephrine, Normal saline
- Where
- 2 sites in Canada
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Pierre Beaulieu
Postoperative Pain
The Effect of Local Anaesthetic Volume on Nerve Block Duration and Nerve Block Duration Variability
The aim is to investigate the effect of perineural administration of a series of different volumes of local anaesthesia (ropivacaine 0.2%) on nerve block duration and the variability of the duration in the common peroneal nerve…
- Trial name
- NCT02829697
- Testing
- Ropivacaine
- Where
- Denmark
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Diabetes Mellitus, Diabetic Neuropathy
Effects of Ankle Block on Postoperative Analgesia in Diabetic and Non-Diabetic Patients
This prospective observational study aims to evaluate the effects of ultrasound-guided ankle block on sensory and motor block characteristics and postoperative analgesic outcomes in patients undergoing lower extremity surgery.
- Conditions
- Diabetes Mellitus, Diabetic Neuropathy, Postoperative Pain Management
- Trial name
- ANKLE-DM (NCT07404124)
- Testing
- Ultrasound-Guided Ankle Block
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Children, Appendicitis
Quadratus Lumborum Block Versus Transversus Abdominis Plane Block in Children Undergoing Laparoscopic Appendicectomy
QL block has been recently described for chronic pain following abdominal hernia repair, and for postoperative analgesia following abdominal surgery as it leads to complete pain relief in the dermatomal area from (T6 - L1).
- Trial name
- NCT04031196
- Testing
- QLB, TAP block
- Where
- Egypt
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Zagazig University
Supraclavicular Brachial Plexus Block
Th Effects of a Drug Dexmedotemidine in Regional Anesthesia in Participants Undergoing Upper Limb Surgeries
In this study, we will assess the effect of combined Dexmedetomidine and Bupivacaine analgesia on the onset and duration of anesthesia in supraclavicular plexus block compared to Bupivacaine alone.
- Trial name
- NCT04981951
- Testing
- Dexmedetomidine
- Where
- Palestinian Territories
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Zaher Nazzal
Other Acute Postoperative Pain, Pain, Postoperative
Effects of Local Anaesthetic Infusion Rates on Nerve Block Duration
This trial is a part of the project: 'A novel technique for reliable, precise and safe postoperative pain management' (project no. 65-2014-3).
- Conditions
- Other Acute Postoperative Pain, Pain, Postoperative, Anaesthesia
- Trial name
- NCT02801799
- Testing
- Varying infusion rates of Ropivacaine 0.2%
- Where
- Denmark
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nordsjaellands Hospital
Regional Anesthesia Morbidity
A Comparison of Peripheral Nerve Catheter Securement Techniques at the Insertion Site in Healthy Volunteers
Continuous peripheral nerve block catheters are used for prolonged analgesia, but are often associated with complications such as catheter failure or dislodgement.
- Trial name
- NCT03375190
- Testing
- Dressing, Dressing + adhesive, Experimental: Dressing + adhesive + strips (parallel)
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Duke University