Clinical trials: Anesthesia Care
Flumazenil Adverse Reaction, Ambulatory Surgery
Reversal of Remimazolam by a Single Dose of Flumazenil
Remimazolam, a brand-new sedative which has benzodiazepine property. It is an ultra-short acting sedative and regarded as a proper drug for procedural sedation.
- Conditions
- Flumazenil Adverse Reaction, Ambulatory Surgery, Postoperative Nausea, Remimazolam
- Trial name
- NCT05382806
- Testing
- Flumazenil
- Where
- South Korea
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Konkuk University Medical Center
Dexmedetomidine, Sedation
Safety Exploration and Evaluation of Dexmedetomidine Hydrochloride Nasal Spray for Pre-anesthesia Sedation in Low-Monitoring Settings
The goal of this clinical trial is to assess the viability of dexmedetomidine hydrochloride nasal spray under minimal or no supervision and to further investigate novel clinical applications for this medication.
- Conditions
- Dexmedetomidine, Sedation, Safety, Preanesthetic Medication
- Trial name
- NCT07298525
- Testing
- Dexmedetomidine hydrochloride nasal spray
- Volunteers
- 564 people, healthy volunteers welcome
- Sponsor
- Sichuan Provincial People's Hospital
Magnetic Resonance Imaging, Anesthesia
Two Anesthetic Techniques in Magnetic Resonance Imaging (MRI)
The goal of this study is to determine if there is a significant difference in the quality of care between the investigators' two standard anesthesia techniques for children undergoing a MRI of the body and/or extremity MRI.
- Trial name
- NCT00894751
- Testing
- dexmedetomidine, propofol
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Anesthesia Residents, Critical Care Staff
Relation Between Workload and Coping Strategy Among Newly Recruited Anesthesia and Critical Care Residents
This survey aims to find the relation, if any, between the perceived work load and the adopted coping strategy among newly recruited anesthesia and critical care residents.
- Trial name
- NCT07873788
- Testing
- NASA-TLX to assess the perceived work load
- Volunteers
- 83 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Anesthesia
Educating Anesthesia Residents to Improve Perioperative Care for the Elderly
1. The investigators will design, test and implement a education curriculum for anesthesia residents teaching geriatric anesthesiology. 2.
- Trial name
- NCT03008863
- Testing
- Education
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Duke University
Contraception, Pain, Acute
Empathy Through Pain Control: Lidocaine Gel vs. Placebo Prior to IUD Placement
The goal of this research study is to learn more about how different uses of a numbing medication might affect pain levels while getting an IUD placed.
- Conditions
- Contraception, Pain, Acute, Anesthesia, Local
- Trial name
- EPIC3 (NCT06974032)
- Testing
- Xylocaine jelly 2%, Surgilube
- Volunteers
- 68 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Breast Diseases
MAC vs TIVA Ambulatory Breast Augmentation
hypothesis: the combination of LA with remifentanil and ketofol [monitored anesthesia care (MAC)] for ambulatory breast augmentation may result in results in better QoR on day of surgery as compared with total i.v.
- Trial name
- NCT03764267
- Testing
- Remifentanil, general anesthetic
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Target Controlled Infusion, Intracranial Neoplasm
Comparison of Opioid Consumption During TCI Guided by NOL Index or Standard Care Undergoing Intracranial Tumor Surgery
In this prospective, randomized controlled study, we hypothesized that nociception level index monitoring reduced opioid administration during surgery.
- Conditions
- Target Controlled Infusion, Intracranial Neoplasm, Opioid, Nociceptive Pain
- Trial name
- NOLopioid (NCT05732896)
- Testing
- Nociception Leve Indeks
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Turkish Society of Anesthesiology and Reanimation
Perioperative Care, EEG Power Spectra
Extended Emergence Strategy on Post-Anesthesia Care Unit Events After Outpatient Orthopedic Surgery
The goal of this clinical trial is to learn if an extended emergence from anesthesia can improve recovery room (Post-Anesthesia Care Unit or PACU) outcomes in lower-leg or foot surgery with nerve blocks.
- Conditions
- Perioperative Care, EEG Power Spectra, Delirium - Postoperative
- Trial name
- PACU-EMERGE (NCT07533370)
- Testing
- Standard of Care EEG-Guided Emergence, Extended EEG Emergence Trajectory
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Harrison Shong-Wen Chow
Monitored Anesthesia Care, Gastrointestinal Endoscopy
The Routine Use of Nasopharyngeal Airway in the Setting of Monitored Anesthesia Care During Gastrointestinal Endoscopy
The goal of this prospective, multi-center, single-blinded randomized controlled trial is to assess the efficacy of NPA in reducing respiratory events in patients being admitted for GI endoscopy (colonoscopy, gastroscopy…
- Conditions
- Monitored Anesthesia Care, Gastrointestinal Endoscopy, Nasopharyngeal Airway
- Trial name
- NCT04123821
- Testing
- Nasopharyngeal airway
- Where
- Lebanon
- Volunteers
- 334 people, healthy volunteers welcome
- Sponsor
- American University of Beirut Medical Center
Anesthesia, Local
Ice as an Adjunct for Local Anesthesia During Anorectal Surgeries
The purpose of this study is to determine, among patients receiving elective anorectal surgery, does application of ice to the perianal area prior to the procedure, lead to use of decreased amounts of intravenous (IV) anesthesia?…
- Trial name
- NCT04000191
- Testing
- MAC, Perianal ice application
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Boston Medical Center
Adverse Effect of Unspecified General Anesthetics
Effect of Coughing on Oxygenation in the Post Anaesthetic Care Unit
General anaesthesia causes small areas of lung to collapse (referred to as atelectasis) and many strategies are used to prevent or reverse this, but these strategies only temporarily improve lung function and do not persist into…
- Trial name
- NCT01314287
- Where
- United Kingdom
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- NHS Research and Development
Postoperative Nausea and Vomiting, Sore-throat
Do Throat Pack Used in Dental Treatments Under General Anesthesia of Patients Have an Effect on PONV and Sore Throat?
The aim of this study is to investigate the effect of throat packs on PONV in dental treatments under general anesthesia in special health care needs.
- Conditions
- Postoperative Nausea and Vomiting, Sore-throat, Dental Caries
- Trial name
- NCT06169306
- Testing
- throat pack
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Cukurova University
Postoperative Atelectasis
Supine vs Prone Position and Atelectasis Assessed by Lung Ultrasound
Atelectasis frequently develops during and after general anesthesia due to factors such as anesthesia-induced diaphragmatic dysfunction, reduced functional residual capacity, altered ventilation-perfusion matching, and surgical…
- Trial name
- LUS-ATELEC (NCT07320092)
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Airway Management
Survey on COVID-19 Airway Management
The objectives of this study are to analyze the best device for intubation in patients infected by SARS-CoV2 virus during COVID-19 pandemics and to review the optimal methods for airway management in such patients for elective…
- Trial name
- ISAM-COVID (NCT04487977)
- Testing
- Survey
- Where
- Spain
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Spanish Society of Anesthesia and Critical Care (SEDAR)
Monitored Anesthesia Care
The Value of Integrated Pulmonary Index Monitoring in Detecting Respiratory Events
Integrated Pulmonary Index (IPI) is a tool that provides numerical values on a scale of 1-10 based on physiological parameters such as peripheral oxygen saturation (SpO2), pulse rate, respiratory rate, end-tidal carbon dioxide…
- Trial name
- NCT05356819
- Testing
- Smart Capnography™, Microstream®
- Where
- Turkey (Türkiye)
- Volunteers
- 154 people, healthy volunteers welcome
- Sponsor
- Samsun Education and Research Hospital
Hypothermia Following Anesthesia
Study of the Prevalence of Postoperative Hypothermia in Adults Undergoing Non-Cardiac Surgery in Spanish Post-Anesthesia Care Units
The prevalence of Hypothermia in Spanish Post-Anesthesia Recovery Units (in Spanish: "Prevalencia de Hipotermia en las Reanimaciones Españolas" PHRES Study) is a prospective, multicenter observational study that will evaluate how…
- Trial name
- PHRES (NCT07839728)
- Testing
- Postoperative temperature monitoring
- Where
- Spain
- Volunteers
- 1,300 people, healthy volunteers welcome
- Sponsor
- Instituto de Investigación Sanitaria de la Fundación Jiménez Díaz
Preoperative Care, Patient Education
Integrating ChatGPT in Anesthesia
Patients are waiting for surgery longer than ever before. While hospitals are trying to get patients access to surgery as quickly as possible, a shortage of anesthesia doctors (called anesthesiologists) prevents this.
- Conditions
- Preoperative Care, Patient Education, Anesthesia, Artificial Intelligence
- Trial name
- NCT06652854
- Where
- Canada
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Ottawa Hospital Research Institute
Hypotension During Surgery, Surgery-Complications
Incidence of Hypotension in the Post-anesthesia Care Unit (PACU).
The perioperative period poses a heightened risk of complications for patients, including hypotension. While the issue of intraoperative hypotension is well-documented in medical literature, the occurrence and causes of…
- Trial name
- NCT07022210
- Where
- Czechia
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tomas Bata Hospital, Czech Republic
Airway Complication of Anesthesia, Respiratory Complications of Care
Comparison of Deep Versus Awake Tracheal Extubation in Adults
Prospective, randomized, single-blinded controlled study to compare the airway and respiratory complications of deep and awake tracheal extubations in adults.
- Trial name
- CDATE (NCT05361850)
- Testing
- Extubation
- Where
- United States
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- United States Navy