Clinical trials: Anesthesia Outcomes
Obstructive Sleep Apnea, Arrhythmia
Evaluation of Sleep Apnea and Cardiac Rhythm Abnormalities After Surgery Under General Anesthesia
Higher risk of cardiac and respiratory post-operative events is observed in patients with unrecognised Obstructive Sleep Apnea (OSA).
- Trial name
- Etude3A (NCT02833662)
- Testing
- Measure of ODI and heart rhythm
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- University Hospital, Grenoble
Anesthesia
Clinical Outcomes Maxilla: Buffered 1% Lidocaine vs. Non-buffered 2% Lidocaine
Anecdotal data suggest that the buffered form of the local anesthetic is more potent at equal dosages, and a lower dosage of the buffered drug might be used with an effect equal to higher dosage not buffered.
- Trial name
- NCT02747186
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Anesthesia, Local, Pain
Clinical Trial Comparing Effectiveness of Buffered Versus Unbuffered Local Anesthetic in Children Ages 10-12 Years
Local anesthesia is an integral part of clinical pediatric dental practice, but it has challenges. It can be uncomfortable for children, and the risk of adverse events limits how much is used.
- Trial name
- NCT03562481
- Testing
- 1% Buffered Lidocaine 1:100,000 Epinephrine, 2% Unbuffered Lidocaine 1:100,000 Epinephrine
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Anesthesia Airway Management, Respiratory Complications
Deflated and Inflated Cuff Endotracheal Extubations
General anesthesia is a treatment with medicine to make a patient unconscious for surgery. This is sometimes called "being put to sleep" or "being put under." Most of the time, a breathing tube is used to help a machine breathe…
- Trial name
- DICEE (NCT06990308)
- Testing
- Inflated Cuff Extubation, Deflated Cuff Extubation
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Naval Medical Center Camp Lejeune
Anesthesia
Comparison of Total Intravenous Anesthesia Methods in Spinal Surgery (TIVA)
This study aims to compare the effects of the classical Total Intravenous Anesthesia (TIVA) method and multimodal anesthesia protocols created by adding lidocaine and ketamine infusions on postoperative pain management, opioid…
- Trial name
- TIVA (NCT06781177)
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Acute Kidney Injury, Surgery Complications
Real-Time Acute Kidney Injury Perioperative Prediction Clinical Trial
This investigator-initiated, pragmatic trial evaluates whether displaying a machine learning (ML)- derived perioperative AKI risk score-alone or paired with an interruptive Best/Our Practice Advisory (BPA/OPA)-improves…
- Conditions
- Acute Kidney Injury, Surgery Complications, Anesthesia
- Trial name
- ML-AKI (NCT07604662)
- Testing
- EHR-Embedded AKI Risk Score, EHR-Embedded AKI Risk Score with Best Practice Advisory
- Where
- United States
- Volunteers
- 25,518 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Cervical Incompetence
Comparison of Anesthesia Type in Patients Undergoing Transabdominal Cervico Isthmic Cerclage (TCIC)
The investigator aimed to compare the effect of anesthesia on overall postoperative outcomes including post-operative pain score and the fetal well-being (heart rate) in patients undergoing transabdominal cervico isthmic…
- Trial name
- NCT03636048
- Testing
- Bupivacaine Hcl 0.5% Inj, Propofol 10 milligram/ML
- Where
- South Korea
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Hallym University Kangnam Sacred Heart Hospital
Pain
Pain Management Following Dental Treatment Under General Anesthesia
The main goal of this study is to test the efficacy of postoperative pain management for cases undergoing extractions of primary teeth under GA using a validated measure.
- Trial name
- NCT06574516
- Testing
- Ibuprofen 200 mg, paracetamol
- Where
- Jordan
- Volunteers
- 118 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Pain
Patient Controlled Epidural Analgesia Versus Continuous Epidural Infusion: Obstetrical and Neonatal Outcomes
The investigators intend to perform a large randomized trial using standardized obstetrical and anesthetic practice at a single institution to determine the effects of patient controlled epidural analgesia on obstetrical and…
- Trial name
- Epidural (NCT00810914)
- Testing
- bupivicaine epidural, bupivicaine epidural infusion patient epidural, bupivicaine
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- MemorialCare
Pediatric Obesity, Obesity, Childhood
PErioperAtive CHildhood ObesitY
The incidence of childhood obesity is at epidemic levels and increasing in the UK. Obese adults are considered a high-risk group of patients for general anaesthesia with published national guidelines on the best practice…
- Conditions
- Pediatric Obesity, Obesity, Childhood, Overweight and Obesity, Perioperative/Postoperative Complications
- Trial name
- PEACHY (NCT03994419)
- Testing
- Anaesthesia for surgery
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- University Hospital Southampton NHS Foundation Trust
Anesthesia
Clinical Outcomes of Buffered 1% Lidocaine vs. Non-buffered 2% Lidocaine
Anecdotal data suggest that the buffered form of the local anesthetic is more potent at equal dosages, and a lower dosage of the drug might be used with an effect equal to higher dosage not buffered.
- Trial name
- NCT02708433
- Testing
- Lidocaine
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Coronary Artery Disease, Cardiometabolic Risk Factors
Impact of New Anthropometric Indices on Outcomes After Cardiac Surgery
Obesity is associated with a number of risk factors for cardiovascular disease. Body mass index (BMI) is the most commonly recommended and used anthropometric measure to classify general obesity in clinical and epidemiological…
- Conditions
- Coronary Artery Disease, Cardiometabolic Risk Factors, Cardiac Anesthesia, Cardiac Surgery
- Trial name
- NCT05403294
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Anesthesia
Pain Outcomes After Anterior Cruciate Ligament Reconstruction With Posterior Capsular Marcaine Injection
Post-operative pain control following elective anterior cruciate ligament reconstruction continues to be a hurdle for orthopaedic surgeons.
- Trial name
- NCT02826551
- Testing
- Marcaine, Ice, Percocet
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Cedars-Sinai Medical Center
Preoperative Fasting, Perioperative Anxiety
Preoperative Fasting and Perioperative Outcomes in Children Undergoing Elective Circumcision
This prospective observational study aims to evaluate adherence to preoperative fasting guidelines and investigate the relationship between actual fasting durations, anxiety levels, and blood glucose levels in children aged 1-10…
- Conditions
- Preoperative Fasting, Perioperative Anxiety, Perioperative Hypoglycemia
- Trial name
- NCT07876583
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Burcu Ayvazoğlu
Pediatric Patients, Cardiology
A Comparison Of The Effect Of Target-Controlled Infusion Anesthesia And Inhalation Anesthesia
A total of 70 patients who underwent angiographic examination, ASD closure, VSD closure, PDA closure and aortic balloon dilatation were included in this study.
- Trial name
- NCT06265610
- Testing
- TIVA/TCI
- Where
- Turkey (Türkiye)
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University
Emergence Delirium in Pediatric Anesthesia, Perioperative Ketonemia and Its Association With Recovery Outcomes in Children
"KETOMED: Ketonemia and Risk of Emergence Delirium in Children Undergoing General Anesthesia - A Multicenter Observational Study"
The objective of this observational study is to evaluate the relationship between ketonemia and emergence delirium in children undergoing general anesthesia.
- Trial name
- KETOMED (NCT07249736)
- Where
- Spain
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Hospital Clínico Universitario de Valladolid
Neurodevelopmental Disorder, Bilateral Inguinal Hernia
Dexmedetomidine Sedation Versus General Anaesthesia for Inguinal Hernia Surgery in Infants
This is a prospective randomized controlled trial comparing dexmedetomidine sedation with caudal anaesthesia, and general sevoflurane anaesthesia with caudal anaesthesia for inguinal herniotomies in neonates and infants below 3…
- Trial name
- DEGA (NCT02559102)
- Testing
- Dexmedetomidine sedation, General sevoflurane anaesthesia, Caudal anaesthesia
- Where
- Singapore
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- KK Women's and Children's Hospital
Intraoperative Hypotension, Jugular Veins
Internal Jugular Vein Ultrasound and Acute Kidney Injury After Abdominal Surgery
This observational study aims to learn whether changes in the internal jugular vein during anesthesia induction can help predict low blood pressure and kidney injury after surgery. The main questions it aims to answer are: 1.
- Conditions
- Intraoperative Hypotension, Jugular Veins, Hypotension on Induction, General Anesthesia With Propofol
- Trial name
- PRO-JUGULAR (NCT07638306)
- Testing
- Internal Jugular Vein Ultrasound Assesment
- Where
- Romania
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Tîrgu Mureș Emergency Clinical County Hospital, Romania
Thyroid Surgeries, Intraoperative Analgesic Use
qCON/qNOX-Guided Anesthesia in Patients Undergoing Thyroidectomy Surgery
The aim of this study is to evaluate the effect of using the non-invasive Conox monitor on intraoperative opioid consumption. Additionally, the study aims to assess the impact of Conox monitoring on recovery time, postoperative…
- Conditions
- Thyroid Surgeries, Intraoperative Analgesic Use, Anesthesia Depth Monitoring
- Trial name
- NCT07445659
- Testing
- Connox EEG Monitoring, standard anesthesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Kayseri City Hospital
Hypotension After Spinal Anesthesia, Post-Dural Puncture Headache
Effects of Preoperative Coffee Consumption in Cesarean Sections Under Spinal Anesthesia
The prospective study is planned in a university hospital. Spinal anesthesia is widely used for cesarean section currently for its safety, low cost, reliability, easiness to administer, immediate effect, and well-operating…
- Trial name
- NCT05262933
- Testing
- coffee, Water
- Where
- Turkey (Türkiye)
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- TC Erciyes University