Clinical trials: Anesthesia for Cesarean Delivery
Aspiration; Gastric Contents, Anesthesia
An Evaluation of a Liberal Hydration Regimen Before Elective Caesarean Section Using Beside Gastric Ultrasound
The aim of this study is to compare the residual gastric volumes in non-labouring parturients prior to elective Caesarean delivery when fully fasted as per European Society of Anaesthesia pre-operative fasting guidelines against…
- Trial name
- NCT05783427
- Testing
- liberal hydration
- Where
- Ireland
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Coombe Women and Infants University Hospital
Postoperative Pain Control
Ultrasound-guided TAP Block Vs Local Wound Infiltration for Analgesia After Cesarean Section.
Adequate pain control after cesarean delivery is a major concern for both parturients and obstetrician, and it usually comprise a combination of systemic and regional techniques.
- Trial name
- NCT04711096
- Testing
- Ultrasound-guided transversus abdominis plane (TAP) block 0.25% bupivacaine.
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Cesarean Section, Obese Parturient
"Ultrasound vs. Landmark Technique for Spinal Anesthesia in Obese Women Undergoing Cesarean Section"
The goal of this clinical trial is to evaluate whether the ultrasound-assisted technique improves the accuracy and safety of spinal anesthesia compared to the traditional landmark technique in obese women undergoing a cesarean…
- Conditions
- Cesarean Section, Obese Parturient, Ultrasound Guided Subarachnoid Block
- Trial name
- NCT07601542
- Testing
- Landmark-Guided Spinal Anesthesia, Ultrasound-Assisted Spinal Anesthesia
- Where
- Bangladesh
- Volunteers
- 60 people
- Sponsor
- Bangladesh Medical University
Spinal Anesthesia-Induced Hypotension, Preeclampsia
Investigation of the Role of Internal Jugular Vein Collapsibility Index in Predicting Spinal Anesthesia-Induced Hypotension in Preeclamptic Parturients
This prospective, single-center observational study aims to evaluate the predictive value of the internal jugular vein collapsibility index (IJVCI) for spinal anesthesia-associated hypotension in preeclamptic parturients…
- Conditions
- Spinal Anesthesia-Induced Hypotension, Preeclampsia, Cesarean Section
- Trial name
- NCT07496788
- Testing
- Internal Jugular Vein Collapsibility Index Measurement
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Ankara City Hospital Bilkent
Anesthesia, Local
Dexmedetomidine as an Adjuvant to Local Anesthesia in Quadratus Lumborum Block After Cesarean Delivery
Postoperative pain is considered one of the major problems after abdominal operations, so proper pain control is one of the main issues in clinical practice.
- Trial name
- NCT04748224
- Testing
- Bupivacaine 0.25% Injectable Solution, bupivacaine plus dexmedetomidine
- Where
- 2 sites in Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Cairo University
Pain, Acute
Intrathecal Midazolam, Fentanyl and Nalbuphine as Adjuvants to Bupivacaine in Spinal Anesthesia for Cesarean Section
The main limitations of spinal anesthesia are its short duration of action and do not provide prolonged postoperative analgesia when it is performed only with local anesthetics.
- Trial name
- NCT04932083
- Testing
- Bupivacaine, Fentanyl, Nalbuphine
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Benha University
Pain, Post Operative, Cesarean Section Complications
Erector Spinae Plane Block (ESPB) Versus Quadratus Lumborum Block (QLB) for Postoperative Analgesia After Caesarean Section
Management of pain after caesarean section represents an important anesthesiologic issue, since it is often suboptimal, leading to delayed functional recovery and chronic pain.
- Conditions
- Pain, Post Operative, Cesarean Section Complications, Anesthesia, Local, Obstetric Anesthesia Problems
- Trial name
- NCT05348083
- Testing
- ESPB
- Where
- Italy
- Volunteers
- 52 people
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
Caesarean Section, Anesthesia
Audio-recording of Consent for Anaesthesia for Elective Caesarean Section
Informed consent should be obtained from patients (with capacity) before treatment - including anaesthesia - is administered. If the consent process is inadequate, it may lead to poor decision-making and dissatisfaction…
- Trial name
- NCT04238741
- Testing
- Audio-recording of consent for anaesthesia for elective caesarean section
- Where
- United Kingdom
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Chelsea and Westminster NHS Foundation Trust
Hypotension
Dicrotic Notch and Hypotension at Caesarean Under Spinal Anaesthesia
BACKGROUND: Hypotension occurs commonly during spinal anaesthesia for caesarean section and may result in detrimental effects to the mother and foetus.
- Trial name
- DINOCS (NCT02437799)
- Testing
- Dicrotic wave analysis
- Where
- United Kingdom
- Volunteers
- 20 people
- Sponsor
- Sheffield Teaching Hospitals NHS Foundation Trust
Postoperative Pain
Adding Different Additives to Bupivacaine-fentanyl Mixture in Spinal Anesthesia for Cesarean Section
Spinal anesthesia is widely used in cesarean section, but it is associated with high incidence of side effects. To reduce the occurrence of side effects, intrathecal adjuvant was recommended to use in spinal anesthesia, with the…
- Trial name
- NCT04464616
- Testing
- spinal anaesthesia
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University
Hypotension
Norepinephrine To Prevent Hypotension After Spinal Anesthesia For Cesarean Delivery: A Dose Finding Study
Spinal anesthesia is the most common anesthetic technique for elective Cesarean delivery (CD), but the most frequent unwanted side effect is hypotension, which can cause nausea and vomiting, as well as effects on the fetus.
- Trial name
- NCT02654847
- Testing
- Norepinephrine, Normal Saline
- Where
- Canada
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Samuel Lunenfeld Research Institute, Mount Sinai Hospital
Hypotension, Anesthesia
Development of Advanced Double Intravenous Vasopressor Automated (ADIVA) System
Maternal hypotension during spinal anaesthesia for Caesarean delivery may bring various adverse effects. It is therefore important to closely monitor hypotension during spinal anaesthesia, however current technology does not…
- Trial name
- ADIVA (NCT03620942)
- Testing
- Phenylephrine, Ephedrine, ADIVA System
- Where
- Singapore
- Volunteers
- 173 people
- Sponsor
- KK Women's and Children's Hospital
Complications; Cesarean Section
Spinal Aesthesia in Women With Placenta Previa Percreta
Placenta previa percreta is a dangerous complication during surgery. Due to the high risk of hemorrhage, most parturients with placenta previa have to accept cesarean section.
- Trial name
- SAW (NCT02686242)
- Testing
- spinal anesthesia, general anesthesia
- Where
- China
- Volunteers
- 68 people
- Sponsor
- Air Force Military Medical University, China
Healthy, Pain
Intrathecal Hydromorphone for Post-cesarean Delivery Pain - a Dose Finding Study
Pain relief after cesarean delivery can be provided in a few ways. Most commonly, certain medications called opioids, such as morphine, are given through the vein or into the muscle.
- Conditions
- Healthy, Pain, Pregnancy
- Trial name
- NCT01943565
- Testing
- Hydromorphone 25mcg, Hydromorphone 50mcg, Hydromorphone 100mcg
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Cesarean Section, Obstetric Anesthesia
Dose and Response of Intrathecal Hydromorphone in Patients Undergoing Cesarean Section at Virginia Commonwealth University Health System
In the United States the incidence of cesarean deliveries have increased over the last several decades and is currently approximately 30% nationwide. The anesthesia and analgesia for elective c-sections vary between institutions.
- Trial name
- NCT02787928
- Testing
- Intrathecal hydromorphone
- Where
- United States
- Volunteers
- 14 people
- Sponsor
- Virginia Commonwealth University
Multiple Gestation, Cesarean Delivery
Incidence of Complications Associated With Anesthesia in Multiple Gestation Undergoing Cesarean Delivery
Incidence of anesthesia related complications in multiple gestation patients undergoing cesarean delivery has not been reported in Thailand.
- Conditions
- Multiple Gestation, Cesarean Delivery, Anesthesia
- Trial name
- NCT02846129
- Where
- Thailand
- Volunteers
- 1,057 people
- Sponsor
- Mahidol University
Placenta Accreta, ESPB
Evaluating the Intraoperative Analgesic Effect of Ultrasound Guided Erector Spinae Plane Block in Parturient Undergoing Elective Cesarean Section for Placenta Accreta Under General Anesthesia.
Due to the significant risk of massive bleeding complicated by profound hypotension and coagulopathy and a high likelihood of hysterectomy during caesarean delivery, general anesthesia is generally regarded as the anesthetic of…
- Conditions
- Placenta Accreta, ESPB, C-section, General Anesthesia
- Trial name
- NCT07748741
- Testing
- ultra sound guided Erector spinae plane block
- Where
- Egypt
- Volunteers
- 70 people
- Sponsor
- Kasr El Aini Hospital
Adverse Effect
90% Effective Dose of Phenylephrine Infusions Under Intensive and Standard Treatment in Preeclamptic Patients
The objective of this study is to investigate the 90% effective dose of phenylephrine infusions for preventing postspinal anesthesia hypotension under intensive and standard treatment in preeclamptic patients during cesarean…
- Trial name
- NCT06151470
- Testing
- Alpha-Agonist, α-adrenergic receptor agonist
- Volunteers
- 80 people
- Sponsor
- General Hospital of Ningxia Medical University
Pre-Eclampsia, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Electroencephalographic Effects of Spinal Anaesthesia During Caesarean Delivery in Preeclampsia
Neuraxial anesthesia has been associated with delayed brainstem conduction and decreasing afferent sensory transmission, thereby modifying reticulo-thalamo-cortical mechanisms regulating arousal.
- Trial name
- NCT03917342
- Testing
- EEG measure
- Where
- Switzerland
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Anesthesia, Adverse Effect
Pharmacokinetics of BPV Following Bilateral US-guided TAP Block for C-section
The transversus abdominis plane block (TAP block) is an effective method of postoperative pain management after cesarean section (C-section).
- Conditions
- Anesthesia, Adverse Effect, Cesarean Section, Transversus Abdominis Plane Block
- Trial name
- NCT03006042
- Testing
- Bupivacaine
- Volunteers
- 17 people
- Sponsor
- University Tunis El Manar