Clinical trials: Anorexia
Eating Disorders
Personality Pathology and Cerebral Processing in Eating Disorders
The proposed study will investigate whether, on the basis of personality traits and personality disorders as well as specific cerebral activation patterns shows differences in adolescent female with anorexia nervosa (AN), bulimia…
- Trial name
- EAT_FMRI (NCT02980120)
- Testing
- SCID-I, EAT, EDI-2
- Where
- Austria
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Medical University Innsbruck
Anorexia Nervosa
Metabolic Phenotyping in Anorexia Nervosa
After discharge from inpatient treatment, 30-50% of patients with Anorexia Nervosa require re-hospitalization within 4-12 months.
- Trial name
- NCT02087280
- Where
- Germany
- Volunteers
- healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Body Dysmorphic Disorders, Anorexia
Evaluation of Brain Opioid Receptor Activity in Anorexia Nervosa : a PET [11C]Diprenorphine Study
The place of opioid system in anorexia nervosa (AN) physiopathology is still unclear. Conflicting results were published on cerebral spinal fluid or peripheral levels in anorexia nervosa.
- Trial name
- NCT02524301
- Testing
- Positron Emission Tomography using [11C]diprenorphine
- Where
- 3 sites in France
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Eating Disorders
STERK - Strength Training and Eating Disorders
Strength training has been found effective for enhancement of bone health, muscle strength and body composition among premenopausal women from the general population, however it is unclear to what extend strength training might…
- Trial name
- NCT02142439
- Testing
- Strength training
- Where
- 3 sites in Norway
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- University of South-Eastern Norway
Anorexia Nervosa
Gastrointestinal Interoception in Anorexia Nervosa
Anorexia nervosa (AN) has among the highest mortality rate of any psychiatric illness, yet we have a poor understanding of the biological causes of this disorder.
- Trial name
- NCT05111977
- Testing
- Vibrant capsule
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Laureate Institute for Brain Research, Inc.
Anorexia Nervosa
Hormonal And Metabolic Signatures In Human Hypothalamic Neurons In Anorexia Nervosa
The goal of this observational study is to investigate cellular mechanisms of neuroendocrine and metabolic signaling in adult women with anorexia nervosa (AN) compared to healthy controls.
- Trial name
- HOPE (NCT07580209)
- Where
- Switzerland
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Maria Miletta
Bulimia Nervosa, Anorexia Nervosa
Avoidance-driven Decision Making and Learning in Anorexia Nervosa and Bulimia Nervosa
The purpose of this study is to investigate areas of the brain responsible for avoidance learning in adults with eating disorders using brain imaging techniques, computer tasks, and self-report questionnaires and interviews.
- Trial name
- NCT06566612
- Where
- United States
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Anorexia Nervosa
Footbaths With Ginger, Mustard & Warm Water Only in Female Adolescents With & Without Anorexia Nervosa
A randomized, controlled, three-arm study to investigate the effects of footbaths with ginger, mustard or warm water alone in female, adolescent patients with Anorexia nervosa and in healthy, female adolescents on…
- Trial name
- NCT03519698
- Testing
- Warm water, Mustard, Ginger
- Where
- Germany
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Anorexia Nervosa
Investigation of Psycho-Physiological Parameters in Adolescent Inpatients With Anorexia Nervosa
A study to assess changes in mental and physical symptoms in adolescent inpatients with anorexia nervosa, a severe eating disorder.
- Trial name
- NCT04083989
- Testing
- Integrative medicine-based multimodal treatment
- Where
- Germany
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- ARCIM Institute Academic Research in Complementary and Integrative Medicine
Aging, Appetite Loss
Effect of a Novel Protein Supplement on Appetite in Older Adults
An acute randomized crossover trial comparing the effects of the whey hydrolysate, whey protein concentrate and placebo (still flavored water) on appetite and energy intake in older adults.
- Trial name
- NCT05871060
- Testing
- Whey Protein Concentrate, Whey hydrolysate
- Where
- Ireland
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- University College Dublin
Anorexia Nervosa, Bulimia Nervosa
Neurobiology of Anorexia and Bulimia Nervosa
The purpose of this study is to investigate areas of the brain responsible for appetite regulation. More specifically, the investigators would like to study changes in brain activation, e.g., changes in blood flow and oxygen use…
- Trial name
- NCT04626219
- Testing
- Imaging, fast, regulated meals
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Anorexia Nervosa Restricting Type, Anorexia Nervosa (DSM-IV Revised Criteria)
Biomarkers in EV Associated With Marrow Adiposity in Anorexia
The aim of this observational study is to identify biomarkers in extracellular vesicles associated with medullary adiposity occurring in patients with anorexia nervosa.
- Trial name
- VE_BMAT_AN (NCT06712485)
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Anorexia Nervosa, Atypical Anorexia Nervosa
Parent Emotion Coaching for Anorexia Nervosa
Family based treatment (FBT) is the evidence based treatment for pediatric anorexia nervosa (AN), but 50% of adolescents do not respond and the consequences for non-response are dire (e.g., 11.5% mortality rate).
- Trial name
- NCT04421989
- Testing
- Emotion Coaching, Support Group
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Eating Disorders, Anxiety
Excessive Avoidance Behaviors in Anorexia Nervosa: the Role of Reward
This study investigates excessive avoidance behaviors in patients with a diagnosis of Anorexia Nervosa (AN) compared to a healthy control group.
- Conditions
- Eating Disorders, Anxiety, Anorexia Nervosa
- Trial name
- NCT04405440
- Testing
- Behavioral avoidance task
- Where
- 2 sites in Belgium
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bram Vervliet
Eating Disorders, Psychiatric Comorbidities
Structural Brain Volumetry Changes in Eating Disorders.
The goal of this observational study is to investigate the relationship between structural brain changes and psychiatric comorbidities in individuals diagnosed with eating disorders (EDs).
- Trial name
- NCT07131852
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assiut University
Disordered Eating
Self-Guided Personalized Treatment for Women
The investigators plan to collect preliminary data on the feasibility, acceptability, and user uptake of a personalized self-guided mobile intervention for disordered eating (DE) and test the initial clinical efficacy of this…
- Trial name
- NCT05920720
- Testing
- Self-guided Personalized Treatment
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Appetite Depressant, Overweight
Safety, Tolerability, Kinetics and Efficacy Study of Hoodia Gordonii Purified Extract (PYM50717)
The objective of this clinical study was to assess the safety, tolerability, efficacy (effects on appetite scores, food intake) and plasma kinetics of Hoodia gordonii purified extract (H.g.PE), when consumed twice-daily for 2 or…
- Conditions
- Appetite Depressant, Overweight, Body Weight
- Trial name
- NCT01306422
- Testing
- Hoodia gordonii purified extract (H.g.PE)
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Unilever R&D
Anorexia Nervosa
Functional Magnetic Resonance Imaging (fMRI) Imaging Study in Adolescents With Anorexia Nervosa
The purpose of this study is to use fMRI imaging technology to examine areas in the brain related to appetite, reward and cognition in adolescent women with eating disorders as compared to those who have never had an eating…
- Trial name
- ADOL_AN (NCT00978666)
- Where
- United States
- Volunteers
- 58 people, healthy volunteers welcome
- Sponsor
- University of California, San Diego
Obesity
Safety & Tolerability of a Combination of Antidepressant and Peptic Ulcer Drug in Overweight Healthy Subjects
The hypothesis of this study is that up to 150 mg of sertraline and up to 3 mg of telenzepine will be safe, tolerable, and have the effect of suppressing appetite, when taken in combination daily by mouth by healthy, overweight…
- Trial name
- NCT01155531
- Testing
- Sertraline plus Telenzepine
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Theracos
ARFID, Anorexia Nervosa
Cognitive Evaluation of Patients With Eating Disorders
The goal of this cross - sectional observational study is to improve understanding of the psychological and cognitive characteristics of Feeding and Eating Disorders (FEDs), a group of conditions that represent a growing public…
- Conditions
- ARFID, Anorexia Nervosa, Bulimia Nervosa, Cognitive Flexibility
- Trial name
- DNA_ARFID (NCT07478510)
- Testing
- Go/No-go, IAT, WCST
- Where
- 3 sites in Italy
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Istituti Clinici Scientifici Maugeri SpA