Clinical trials: Anxious-Depressive
Major Depressive Disorder, General Anxiety Disorder
Emotional Brain Networks & Cognitive Functioning in Depression and Anxiety
This study aims to 1) examine common and specific emotional and cognitive dysfunctions between Major Depression and generalized anxiety disorder; 2) Examine emotional and cognitive dysfunctions between the two disorders and…
- Trial name
- NCT03084042
- Testing
- fMRI
- Where
- China
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Chronic Condition, Chronic Pain
RIVER At Home Ketamine Protocols
Multiple site studies with the recruitment of other sub-investigators and sites. It's sobering to consider how chronic illness makes us more vulnerable to suicidal thoughts and behavior.
- Conditions
- Chronic Condition, Chronic Pain, Chronic Disease, Major Depressive Disorder
- Trial name
- NCT06070766
- Testing
- Ketamine
- Where
- 2 sites in United States
- Volunteers
- 50,000 people
- Sponsor
- RIVER Foundation
Depressive Disorder, Depressive Symptoms
Super Skills for Life Effectiveness in Clinical Settings
Super Skills for Life (SSL) is a transdiagnostic cognitive-behavioral protocol developed for children aged 6 to 12 with anxiety and comorbid problems (e.g., depression, low self-esteem, and lack of social skills).
- Conditions
- Depressive Disorder, Depressive Symptoms, Trauma and Stressor Related Disorders, Anxiety Disorders and Symptoms
- Trial name
- NCT05482724
- Testing
- Super Skills for Life
- Where
- Spain
- Volunteers
- 74 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Major Depressive Disorder
Neural Circuit Effects of Ketamine in Depression
This project is designed to examine the role of the subgenual anterior cingulate cortex (sgACC) in anhedonia and anxiety in humans with depression, as well as the acute and sustained effects of ketamine on agACC activation and…
- Trial name
- NCT06213324
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai
Schizophrenia, Drug Abuse
A Pilot, Proof-of-concept Cohort Study of the Prevalence of Comorbid Mental Illness and Substance Abuse
The prevalence estimates for specific mental disorders and illicit drugs have been separately reported in U.S. government surveys.
- Conditions
- Schizophrenia, Drug Abuse, Anxiety Disorder, Bipolar Disorder
- Trial name
- NCT02476877
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Advanced Clinical Laboratory Solutions, Inc.
Anxiety, Depression - Major Depressive Disorder
Transcendental Meditation Intervention to Reduce Burnout and Enhance Resilience Among NewYork-Presbyterian Hospital and Weill Cornell Medicine Employees and Residents
The goal of this study is to learn if a meditation intervention called Transcendental Meditation or TM can be used in a small department at Weill Cornell Medicine to help reduce employees' levels of burnout, anxiety, insomnia…
- Conditions
- Anxiety, Depression - Major Depressive Disorder, Burnout, Insomnia
- Trial name
- NCT07868783
- Testing
- Transcendental Meditation
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Anxiety Disorder, Depressive Disorder
OcupApp: Occupational Self-analysis Intervention Through an Mobile Application
The goal of this clinical trial is to test the effectiveness of the use of mobile application ("OcupApp") to generate a personal self-analysis about meaningful activities in which adults between the ages of 50 and 70 with anxiety…
- Conditions
- Anxiety Disorder, Depressive Disorder, Occupational Therapy, Mobile App
- Trial name
- OcupApp (NCT05867823)
- Testing
- OcuApp, Three-part work
- Volunteers
- 134 people
- Sponsor
- University of Malaga
Major Depressive Disorder, Mood Disorder
Laughter Yoga Intervention for People With Major Depressive Disorder
The present study will adopt a non-blinded parallel-group randomized controlled trial design that involves a Laughter Yoga group (intervention) and a treatment-as-usual group (Control).
- Conditions
- Major Depressive Disorder, Mood Disorder, Depression
- Trial name
- NCT03163940
- Testing
- Laughter Yoga
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- The Hong Kong Polytechnic University
Alzheimer Disease
Connected Solution of Assistance Dedicated to Caregivers and People With Alzheimer's Disease or Related Diseases
Alzheimer's disease and related diseases (ADRD) are a major public health issue. In France, nearly 900,000 people have ADRD, which represents about 70% of dementia cases, and the expected prevalence for 2020 is 1.2 million.
- Trial name
- Lili smart (NCT03295110)
- Testing
- Functionalities of the Lili Smart Solution activated, Functionalities of the Lili Smart Solution non activated
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospices Civils de Lyon
Depressive Disorder, Anxiety Disorders
Internet-delivered Treatments for Depression and Anxiety in Primary Care (SUMMA)
The current study is an open feasibility trial with the aim of providing a description of the factors associated with the implementation of an iCBT platform into an existing treatment framework in a primary care setting.
- Conditions
- Depressive Disorder, Anxiety Disorders, Depression
- Trial name
- NCT03068676
- Testing
- Space from Depression, Space from Anxiety
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Silver Cloud Health
Depression - Major Depressive Disorder, Anxiety
Clinical Impact of an Anti-Inflammatory Diet in Anxiety and Depression With AI
The goal of this clinical trial is to evaluate the effectiveness of an anti-inflammatory dietary intervention on physical health, mental health, and cognitive functioning in individuals with clinically diagnosed anxiety and/or…
- Trial name
- NCT07398040
- Testing
- Anti-inflammatory diet, Control
- Where
- Spain
- Volunteers
- 60 people
- Sponsor
- Universidad de Zaragoza
Emotion Regulation, Depressive Symptoms
Music Program for Hong Kong Adolescents: Improving Emotion Regulation and Reducing Depression, Anxiety, and Loneliness
This study is a clinical trial that aims to test and validate a music-based program called "Tuned In" in helping adolescents in Hong Kong improve their mental well-being.
- Conditions
- Emotion Regulation, Depressive Symptoms, Anxiety, Loneliness
- Trial name
- NCT06147297
- Testing
- Tuned In
- Where
- Hong Kong
- Volunteers
- 133 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Major Depressive Disorder, Anxiety
The Safety, Efficacy, and Tolerability of Microbial Ecosystem Therapeutic-2 in People With Major Depression
To measure the effects of Microbial Ecosystem Therapeutics (MET)-2 on symptoms of depression and anxiety using pre- and post-treatment scores for overall depression and anxiety
- Trial name
- NCT04602715
- Testing
- MET-2
- Where
- 2 sites in Canada
- Volunteers
- 60 people
- Sponsor
- NuBiyota
Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8
Cognitive-Behavioral Stress Management Device for the Treatment of Anxiety and Depressive Symptoms in Patients With Stage I-III Breast or Lung Cancer
This phase II trial studies the effect of a digital application (app), BNT001, on cognitive-behavioral stress management in patients with stage I-III breast or lung cancer.
- Conditions
- Anatomic Stage I Breast Cancer AJCC v8, Anatomic Stage IA Breast Cancer AJCC v8, Anatomic Stage IB Breast Cancer AJCC v8, Anatomic Stage II Breast Cancer AJCC v8
- Trial name
- BNT001 (NCT04705025)
- Testing
- Cognitive Behavior Therapy, Interview, Quality-of-Life Assessment
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Jonsson Comprehensive Cancer Center
Depressive Disorder and Anxiety Disorders
Relative Bioavailability and Food Effect Study for GSK163090 in Healthy Male and Female Volunteers
The study will consist of a screening period, 3 treatment periods and a post-treatment follow-up. In each of the 3 treatment periods, subjects will receive a single oral dose of GSK163090 in the fed or fasted state, followed by a…
- Trial name
- NCT00536679
- Testing
- GSK163090 capsule, fasted, GSK163090 Tablet, fasted, GSK163090 Tablet, fed
- Where
- Germany
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- GlaxoSmithKline
Recreational Drug Use, Sexual Violence
Evaluation of Teen Connection Project for Trans and Gender Minority Youth
The purpose of this project is to develop and evaluate an online mentoring and skill-building program for transgender and/or gender minority youth (TGMY) ages 14 to 18, the Teen Connection Project (TCP).
- Conditions
- Recreational Drug Use, Sexual Violence, Victimisation, Depressive Symptoms
- Trial name
- TCP (NCT06587139)
- Testing
- Teen Connection Project (TCP)
- Where
- United States
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Social Skills, Perfectionism
Effectiveness of the Universal Prevention Program Super Skills for Life in Schools
This study aims to evaluate the effectiveness of a 12-session cognitive-behavioral transdiagnostic protocol for Spanish children aged 8 to 12 within an educational context, Super Skills for Life.
- Conditions
- Social Skills, Perfectionism, Self Esteem, Positive Affect
- Trial name
- NCT06444581
- Testing
- Super Skills Schools
- Where
- Spain
- Volunteers
- 1,100 people
- Sponsor
- Universidad Miguel Hernandez de Elche
Major Depression With Comorbid Anxiety Symptoms
A Double Blind, Randomized Placebo Controlled Study of the Efficacy, Safety and of Quetiapine Fumarate (Seroquel®) as Potentiation SSRI's, and SNRI's Treatment in Major Depression With Anxiety
Major depression occurs with generalized anxiety disorder and panic disorder in up to 60% of psychiatric and primary care patients.(1) An estimated 85% of adults with depression experience significant symptoms of anxiety and 58%…
- Trial name
- NCT00229645
- Testing
- Quetiapine Fumarate (Seroquel®)
- Where
- Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Dr Alexander McIntyre Inc.
Dysthymic Disorder
Desvenlafaxine Monotherapy in Dysthymia
This multi-centred study will be conducted at two centres. The design will be an open label, flexible-dose study. This investigation will evaluate the efficacy of Desvenlafaxine monotherapy for patients who meet diagnostic…
- Trial name
- NCT01948895
- Testing
- Desvenlafaxine
- Where
- 2 sites in Canada
- Volunteers
- 30 people
- Sponsor
- Centre for Addiction and Mental Health
Major Depressive Disorder, Dysthymic Disorder
Quetiapine in Co-Morbid Depressive and Anxiety Disorders
This multi-centred study will be conducted at three centres. The design will be a randomized, placebo-controlled, parallel-group one.
- Conditions
- Major Depressive Disorder, Dysthymic Disorder, Anxiety Disorders, Generalized Anxiety Disorder
- Trial name
- NCT00688818
- Testing
- Quetiapine
- Where
- 4 sites in Canada
- Volunteers
- 108 people
- Sponsor
- Centre for Addiction and Mental Health