Clinical trials: Apraxia
Developmental Coordination Disorder, Developmental Dyspraxia
Reliability and Validity of a Computerized Tool to Assess Proprioception Among Children With Coordination Disorders
Coordination disorders are common among children that arrive to child development services. Children with coordination disorders have impaired proprioceptive sensation and motor planning.
- Conditions
- Developmental Coordination Disorder, Developmental Dyspraxia, Clumsy Child Syndrome
- Trial name
- NCT03285776
- Where
- Israel
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Jay Zuckerman
Specific Developmental Disorders of Speech and Language, Specific Learning Disorder
Ambulatory Screening for Specific Learning Disabilities (SLD) and Developmental Coordination Disorder (DCD).
To evaluate, in primary care, the sensitivity of Heterophory-Vertical-Labile (HV-Labile) in ambulatory screening for Specific Learning Disabilities (SLD) and Developmental Coordination Disorder (DCD).
- Conditions
- Specific Developmental Disorders of Speech and Language, Specific Learning Disorder, Dyslexia, Developmental, Developmental Coordination Disorder
- Trial name
- TDys (NCT04122820)
- Testing
- Diagnostic of specific learning disabilities or of Developmental Coordination Disorder
- Where
- France
- Volunteers
- 1,800 people
- Sponsor
- CNGE IRMG Association
Aphasia, Apraxia of Speech
MIRAA - Implementation of Intensive Rehabilitation of Aphasia and/or Apraxia of Speech in Swedish Healthcare
Positive outcomes have been shown following intensive treatment of speech and/or language impairment post stroke, but how to design intensive treatment programs to achieve optimal recovery and neuroplasticity changes needs to be…
- Conditions
- Aphasia, Apraxia of Speech, Stroke
- Trial name
- MIRAA (NCT04957225)
- Testing
- MIRAA (Multimodal Intensive Rehabilitation of Aphasia and Apraxia of speech)
- Where
- Sweden
- Volunteers
- 25 people
- Sponsor
- Karolinska Institutet
Rolandic Epilepsy, Apraxia
Scholar Performance and Praxis Assessment in Children With Rolandic Epilepsy
Rolandic Epilepsy is the most common form of childhood epilepsy. It is classified as idiopathic, age-related epilepsy syndrome with benign evolution.
- Trial name
- NCT01046760
- Testing
- Language Assessment
- Where
- Brazil
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Campinas, Brazil
Carotid Artery Stenosis, Carotid Artery Stenting
Innovative Application of Pressure Gradient Measurement in Internal Carotid Stenosis in Patients Undergoing CAS
About 20% of stroke causes are atherosclerotic strokes caused by carotid artery stenosis. In 2005, 92% of carotid artery interventions in the USA were performed in asymptomatic patients.
- Conditions
- Carotid Artery Stenosis, Carotid Artery Stenting, Stroke
- Trial name
- NOTICE-CAS (NCT06123767)
- Testing
- CAS + Intravascular measuring the pressure gradient, CAS (standard), Doppler ultrasonound of cephalic arteries
- Where
- Poland
- Volunteers
- 200 people
- Sponsor
- 4th Military Clinical Hospital with Polyclinic, Poland
Childhood Apraxia of Speech
The Effects of Caregiver Training on DTTC Treatment Outcomes in CAS
The goal of this clinical trial is to investigate the impact of direct vs. indirect caregiver training on treatment outcomes following a period of Dynamic Temporal and Tactile Cueing (DTTC) intervention combined with home…
- Trial name
- DTTC (NCT05916222)
- Testing
- Dynamic Temporal and Tactile Cueing (DTTC)
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- New York University
Carotid Artery Stenoses
SPI-guided Analgesia During CEA Under RA
The aim of this randomized prospective trial is to assess the utility of Adequacy of Anaesthesia technique (Response Entropy and Surgical Pleth Index) for monitoring pain perception intraoperatively, maintainance of hemodynamic…
- Trial name
- CEA (NCT04500249)
- Testing
- infiltration rescue intraoperative analgesia, rescue IA, rescue antyhypertensive medication
- Where
- Poland
- Volunteers
- 105 people
- Sponsor
- Medical University of Silesia
Apraxia, Oral, Apraxia of Speech
Motor Imagery for Treatment Enhancement and Efficacy in Persons With Apraxia of Speech
Treatment of post-stroke apraxia of speech (AOS) requires frequent and ongoing practice with a speech-language pathologist to facilitate lasting behavioral change, which is costly and, therefore, inaccessible to many patients.
- Trial name
- MI-TEE (NCT06467136)
- Testing
- Sound production treatment, Motor Imagery Practice
- Where
- United States
- Volunteers
- 18 people
- Sponsor
- University of Central Florida
Stroke, Dysarthria
Deep Brain Stimulation + Therapy for Stroke
The purpose of this study is to evaluate the safety and potential benefits of combining deep brain stimulation (DBS) with targeted speech and swallowing rehabilitation in individuals who have experienced a stroke and have…
- Conditions
- Stroke, Dysarthria, Apraxia, Dysphagia
- Trial name
- NCT07849114
- Testing
- Boston Scientific Vercise Deep Brain Stimulation (DBS) System, Rehabilitation Training Protocol
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Pirondini, Elvira, PhD
Autism Spectrum Disorder, Asperger Syndrome
Effects of a Multimodal Exercise Program for Children With ASD
Exploring the effects of an exercise program for children ages 6 -26 years old who have been diagnosed with autism spectrum disorder and neurotypical children respond to high-intensity whole body exercise interventions (Group 1)…
- Trial name
- NCT05509231
- Testing
- High-intensity exercise, Wearable glove and arm sleeve device to measure movement
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- New York Institute of Technology
Ataxia-oculomotor Apraxia 1
Evolution of Albumin on AOA1 Patients Supplemented With Coenzyme Q10
We propose a study on Ataxia with oculomotor apraxia type 1 (AOA1) in which Coenzyme Q10 (CoQ10) deficit has been observed. Main objectives of the study are : To monitor evolution of albumin in patients affected with AOA1 while…
- Trial name
- AOA1 (NCT02333305)
- Testing
- CoQ10
- Where
- France
- Volunteers
- 19 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Childhood Apraxia of Speech, Verbal Apraxia
Role of Omega-DEK in Childhood Apraxia of Speech
This is a 20-week study for children between 3 and 6 years old with confirmed childhood apraxia of speech (CAS). The study includes a 12-week open-label pilot feasibility study of an investigational drug (Omega-DEK) plus…
- Conditions
- Childhood Apraxia of Speech, Verbal Apraxia, Autism
- Trial name
- NCT07216001
- Testing
- Omega-DEK, L-carnitine
- Where
- 2 sites in United States
- Volunteers
- 34 people
- Sponsor
- Claudia R. Morris
Childhood Apraxia of Speech
Dose Frequency RCT on DTTC in Children With CAS
Childhood apraxia of speech (CAS) is a pediatric motor-based speech sound disorder that requires a specialized approach to intervention (Maas et al., 2014).
- Trial name
- NCT05675306
- Testing
- Dynamic Temporal and Tactile Cueing Treatment
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Marquette University
Rare Disorders, Undiagnosed Disorders
Rare Disease Patient Registry & Natural History Study - Coordination of Rare Diseases at Sanford
CoRDS, or the Coordination of Rare Diseases at Sanford, is based at Sanford Research in Sioux Falls, South Dakota. It provides researchers with a centralized, international patient registry for all rare diseases.
- Conditions
- Rare Disorders, Undiagnosed Disorders, Disorders of Unknown Prevalence, Cornelia De Lange Syndrome
- Trial name
- CoRDS (NCT01793168)
- Where
- 2 sites in United States, Australia
- Volunteers
- 20,000 people
- Sponsor
- Sanford Health
Ataxia, Cerebellar, Cerebellar Ataxia
Rehabilitative Trial With Cerebello-Spinal tDCS in Neurodegenerative Ataxia
Neurodegenerative cerebellar ataxias represent a group of disabling disorders for which we currently lack effective therapies. Cerebellar transcranial direct current stimulation (tDCS) is a non-invasive technique, which has been…
- Conditions
- Ataxia, Cerebellar, Cerebellar Ataxia, Spinocerebellar Ataxias, Ataxia, Spinocerebellar
- Trial name
- CStDCSAtaxia (NCT03120013)
- Testing
- Anodal cerebellar and cathodal spinal tDCS
- Where
- Italy
- Volunteers
- 21 people
- Sponsor
- Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
Stroke, Aphasia
Evaluating Anodal tDCS Preceding Aphasia Therapy
The purpose of this study is to determine if non-invasive brain stimulation (transcranial direct current stimulation) delivered prior to language therapy will improve word-finding in individuals with aphasia who are 6 months or…
- Trial name
- NCT02249819
- Testing
- transcranial direct current stimulation
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Northwell Health
Multiple Sclerosis, Apraxia
Occupational Therapy in Patients With Multiple Sclerosis
Limb apraxia is defined as the inability to correctly perform skilled and/or learned limb movements, which cannot be explained by elementary motor and sensory deficits or cognitive problems.
- Trial name
- NCT01507636
- Testing
- Occupational Therapy, Physical therapy
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Lumbar Disc Disease
SPI-directed Analgesia for Lumbar Discectomy
The aim of this randomized trial is to assess the efficacy of analgesia for lumbar discectomy and compare Numerical Rating Scale (NRS) with Surgical Pleth Index (SPI) for monitoring pain perception postoperatively.
- Trial name
- SPI (NCT02971540)
- Testing
- Metamizol, Tramadol, Bupivacaine
- Where
- Poland
- Volunteers
- 132 people
- Sponsor
- Medical University of Silesia
PPA, Primary Progressive Aphasia
PiB PET Scanning in Speech and Language Based Dementias
The study is designed to determine whether there are clinical features that can be used as biomarkers to predict whether underlying Alzheimer's pathology is the cause of a speech and language based dementia.
- Conditions
- PPA, Primary Progressive Aphasia, Aphasia, Non-fluent Aphasia
- Trial name
- NCT01623284
- Testing
- C-11 PiB, F-18 FDG
- Where
- United States
- Volunteers
- 168 people
- Sponsor
- Mayo Clinic
Apraxia of Speech
Searching of Apraxia of Speech in Children With Specific Language Impairment
Searching of Apraxia of Speech in Children with Specific Language Impairment
- Trial name
- NCT05584033
- Testing
- Mansora Arabic test battery for childhood apraxia of speech
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Sohag University