Clinical trials: Arrest Cardio Respiratory
Cardiac Arrest
Therapeutic Hypothermia to Improve Survival After Cardiac Arrest in Pediatric Patients-THAPCA-IH [In Hospital] Trial
Cardiac arrest is a sudden, unexpected loss of heart function. Therapeutic hypothermia, in which the body's temperature is lowered and maintained several degrees below normal for a period of time, has been used to successfully…
- Trial name
- THAPCA-IH (NCT00880087)
- Testing
- Therapeutic Hypothermia, Therapeutic Normothermia
- Where
- 33 sites in United States, Canada and 1 more
- Volunteers
- 329 people
- Sponsor
- University of Michigan
Cardiac Arrest, Heart Arrest
ECPR for Refractory Out-Of-Hospital Cardiac Arrest
In the U.S. alone, over 300,000 people per year have sudden out-of-hospital cardiac arrest (OHCA), and less than 1 out of 10 survive.
- Conditions
- Cardiac Arrest, Heart Arrest, Sudden Cardiac Arrest, Cardiopulmonary Arrest
- Trial name
- EROCA (NCT03065647)
- Testing
- Expedited Transport With Mechanical CPR
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Michigan
Cardiac Arrest, Respiratory Arrest
Norwegian Cardio-Respiratory Arrest Study
The purpose of this study is to evaluate the use of combined clinical-neurological, neurophysiologic, neuroradiological and biochemical markers in prognostication after cardio- and/or respiratory arrest.
- Conditions
- Cardiac Arrest, Respiratory Arrest, Coma
- Trial name
- NORCAST (NCT01239420)
- Where
- Norway
- Volunteers
- 261 people
- Sponsor
- Oslo University Hospital
Sepsis, Septic Shock
Central Venous Catheter Colonisation Among Critically Ill Patients in Intensive Care Units
Background: Central Venous catheter insertion technique and indwelling time are major risk factors for CVC colonisation. Colonisation occurs through microbial migration and biofilm formation along the catheter insertion tract.
- Conditions
- Sepsis, Septic Shock, Post-cardiac Surgery, Post-Cardiorespiratory Arrest Coma
- Trial name
- NCT03270774
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Makerere University
Cardiac Arrest, Cardiopulmonary Arrest
NEURESCUE Device as an Adjunct to Cardiac Arrest
The NEURESCUE device is the first intelligent balloon catheter for aortic occlusion, an emergency technique that supercharges blood flow to the heart and brain within one minute from deployment.
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest, Cardiovascular Diseases
- Trial name
- ARISE-EU (NCT05146661)
- Testing
- NEURESCUE device
- Where
- 2 sites in Germany
- Volunteers
- 10 people
- Sponsor
- neurescue
Cardiopulmonary Arrest
Extension of Rapid Response Team Operation Time and Cardiopulmonary Resuscitation Incidence
Although early rapid response team was reported as a full-time operating system, similar efficacy of part-time rapid response team has been recently reported.
- Trial name
- NCT05712915
- Testing
- RRT operation
- Where
- South Korea
- Volunteers
- 142,088 people
- Sponsor
- Dong-A University Hospital
Cardiopulmonary Arrest, Resuscitation
Reducing Prehospital Medication Errors & Time to Drug Delivery by EMS During Simulated Pediatric CPR
The study investigators will recruit paramedics in many Emergency Medical Services (EMS) in Switzerland to prepare direct intravenous (IV) emergency drugs during a standardized simulation-based pediatric out-of-hospital cardiac…
- Conditions
- Cardiopulmonary Arrest, Resuscitation, Pediatrics, Medication Errors
- Trial name
- NCT03921346
- Testing
- Mobile device app (PedAMINES™) 1st drug, Mobile device app (PedAMINES™) 2nd drug, Mobile device app (PedAMINES™) 3rd drug
- Where
- Switzerland
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Pediatric Clinical Research Platform
Cardiac Arrest, Cardiopulmonary Arrest
Lowlands Saves Lives: A Randomized Trial Comparing CPR-quality Between Face-to-face vs. Lifesaver VR Training
The objective of the Lowlands Saves Lives trial is to compare the quality of cardiopulmonary resuscitation (CPR) between face-to-face versus Lifesaver Virtual Reality smartphone application trained participants using a randomized…
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest, Out-Of-Hospital Cardiac Arrest
- Trial name
- NCT04013633
- Testing
- Lifesaver virtual reality training, Face-to-face training
- Where
- Netherlands
- Volunteers
- 381 people, healthy volunteers welcome
- Sponsor
- Radboud University Medical Center
Respiratory Failure, Status Epilepticus
Pilot Simulation RCT of Telemedical Support for Paramedics
This study evaluates the impact of video communication via telemedicine on the quality of emergency care provided to children by paramedic teams supported by a remote physician in a simulated out-of-hospital setting.
- Conditions
- Respiratory Failure, Status Epilepticus, Status Asthmaticus, Cardiopulmonary Arrest
- Trial name
- NCT03742167
- Testing
- Telemedicine
- Where
- United States
- Volunteers
- 72 people
- Sponsor
- Boston Medical Center
Cardiac Arrest, Cardiopulmonary Arrest With Successful Resuscitation
Pupillometry and Somatosensory Evoked Potential in Cardiac Arrest
Somatosensory Evoked Potentials (SSEP) and Pupillary Light Reflex (PLR) are key methods for neurologic prognostication in comatose survivors of cardiac arrest.
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest With Successful Resuscitation, Resuscitation
- Trial name
- PASCA (NCT04720482)
- Testing
- Somatosensory Evoked Potentials, Automated Pupillometry
- Where
- Sweden
- Volunteers
- 50 people
- Sponsor
- Sahlgrenska University Hospital
Cardiopulmonary Arrest With Successful Resuscitation, ACS - Acute Coronary Syndrome
Add-on Cangrelor in STEMI-triggered Cardiac Arrest
In patients with ST-elevation myocardial infarction (STEMI) undergoing percutaneous coronary angioplasty (PCI) P2Y12 receptor (P2Y12r) inhibition should be achieved as soon as possible.
- Conditions
- Cardiopulmonary Arrest With Successful Resuscitation, ACS - Acute Coronary Syndrome, Hypothermia, Induced
- Trial name
- NCT03273075
- Testing
- Cangrelor, Prasugrel, Ticagrelor
- Where
- Austria
- Volunteers
- 60 people
- Sponsor
- Medical University of Vienna
Cardiac Arrest, Out-Of-Hospital, Cardiac Arrest With Successful Resuscitation
CardioPulmonary Resuscitation With Argon (CPAr) Trial
Preclinical studies suggest that argon (Ar) might diminish the neurological and myocardial damage after any hypoxic-ischemic insult.
- Trial name
- CPAr (NCT05482945)
- Testing
- Noble gas Argon
- Where
- 9 sites in Italy
- Volunteers
- 120 people
- Sponsor
- Mario Negri Institute for Pharmacological Research
Airway Aspiration, Cardiopulmonary Arrest
Benefit of the SALAD Technique on CPR Quality During Intubation in Contaminated Airway
Management of airways in contaminated environments can compromise the quality of cardiopulmonary resuscitation (CPR). This study examined the effectiveness of SALAD (Suction Assisted Laryngoscopy Airway Decontamination) compared…
- Trial name
- NCT06427655
- Testing
- SALAD intubation
- Where
- Taiwan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Shin Kong Wu Ho-Su Memorial Hospital
Cardiac Arrest, Cardiopulmonary Arrest With Successful Resuscitation
Impact of NIRS-guided Cardiopulmonary Resuscitation After Cardiac Arrest on Resuscitation Rate
Sudden cardiac death is one of the main causes of morbidity and mortality worldwide. Cardiac arrest requires prompt intervention by cardiopulmonary resuscitation (CPR).
- Conditions
- Cardiac Arrest, Cardiopulmonary Arrest With Successful Resuscitation, Cerebral Oxygenation
- Trial name
- NICA (NCT03911908)
- Testing
- Cerebral oximetry (near infrared) based CPR-Algorithm
- Where
- Germany
- Volunteers
- 360 people
- Sponsor
- Dr. Serge Thal
Cardiac Arrest, COVID-19
Impact of Aerosol Box Use During Cardiopulmonary Arrest: A Multicenter Study
Aerosol Generating Medical Procedures (AGMP) are procedures that have the potential to create tiny particles suspended in the air. These particles can contain germs such as viruses.
- Conditions
- Cardiac Arrest, COVID-19, Coronavirus
- Trial name
- NCT05868239
- Testing
- Aerosol box
- Where
- 4 sites in United States, Canada
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- KidSIM Simulation Program
Indication of Orotracheal Intubation, Cardio Respiratory Arrest
Comparative Evaluation of the McGrath Videolaryngoscope and the Direct Laryngoscopy for Tracheal Intubation in the Prehospital Setting
In the prehospital setting, the risk of difficult intubation and life-threatening complications is increased under particular conditions due to the environment or the frequent instability of patients.
- Conditions
- Indication of Orotracheal Intubation, Cardio Respiratory Arrest, Respiratory Failure, Neurological Failure
- Trial name
- AMAC (NCT04930419)
- Testing
- Videolaryngoscopy group, Direct laryngoscopy group
- Volunteers
- 150 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Heart Arrest, Cardiac Arrest
Pre-arrival Instructions Effect on Bystander Cardiopulmonary Resuscitation (CPR).
The investigators hypothesized that pre-arrival instructions would increase the likelihood of bystanders performing Cardiopulmonary Resuscitation (CPR).
- Conditions
- Heart Arrest, Cardiac Arrest, Cardiopulmonary Arrest, Out of Hospital Cardiac Arrest
- Trial name
- NCT02007499
- Testing
- Pre-Arrival Instructions
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- Medical College of Wisconsin
Cardio Respiratory Arrest
Outcomes and Risk Factors of CPR in PICU
1. To detect the frequency and the underlying causes of cardiopulmonary arrest . 2. To detect outcome of CPR 3. To identify the associated risk factors for the different outcomes after CPR among those patients
- Trial name
- NCT06300710
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Assiut University
Cardiopulmonary Arrest, Mechanical Ventilation Complication
Evaluating the Performance of Invasive Ventilation During Specialized CPR
Describe the ventilation patterns, describe the evolution of ventilation over time and describe the safety data for two strategies of ventilation (volume or pression modes) during specialized cardiopulmonary resuscitation of…
- Trial name
- NCT06175689
- Volunteers
- 400 people
- Sponsor
- University Hospital, Angers
Cardiopulmonary Arrest
Effect of the Cardio First Angle Device on CPR Outcomes
The investigators conducted a randomized, controlled, single-blinded study of patients undergoing CPR for cardiac arrest in the mixed medical-surgical ICUs of four academic teaching hospitals in Tehran, Iran from June 1 to…
- Trial name
- CFA (NCT02394977)
- Testing
- Compression with Feedback, Standard chest compression
- Volunteers
- 80 people
- Sponsor
- Baqiyatallah Medical Sciences University