Clinical trials: Arterial Aneurysm
Intracranial Aneurysm
I-CAN Biocollection
Intracranial aneurysm (IA) is an asymptomatic cerebrovascular abnormality affecting 3.2% of the general population. The devastating complication of IA is its rupture, resulting in subarachnoid haemorrhage that can lead to severe…
- Trial name
- I-CAN (NCT02712892)
- Testing
- Non Interventional Study
- Where
- 20 sites in France
- Volunteers
- 3,078 people
- Sponsor
- Nantes University Hospital
Aortic Dissection Aneurysm
Safety and Validity of Extracorporeal Fenestration and in Situ Fenestration in Patients With Aortic Disease Involving the Left Subclavian Artery
This trial aims to demonstrate the safety and validity of extracorporeal fenestration and in situ fenestration in patients with aortic disease involving the left subclavian artery.
- Trial name
- NCT06256757
- Testing
- fenestration
- Volunteers
- 170 people
- Sponsor
- The Fourth Affiliated Hospital of Zhejiang University School of Medicine
Aortic Dissection, Aortic Aneurysm
NEXUS Aortic Arch Clinical Study to Evaluate Safety and Effectiveness
Prospective, non-randomized, multi-center clinical investigation of the NEXUS™ Aortic Arch Stent Graft System (NEXUSTM) for the treatment of thoracic aortic lesions involving the aortic arch with a proximal landing zone, native…
- Conditions
- Aortic Dissection, Aortic Aneurysm, Intramural Hematoma, Penetrating Aortic Ulcer
- Trial name
- TRIOMPHE (NCT04471909)
- Testing
- NEXUS Aortic Stent Graft System
- Where
- 32 sites in United States, New Zealand
- Volunteers
- 110 people
- Sponsor
- Endospan Ltd.
Intracranial Aneurysm
Study on the Effectiveness and Safety of Coil System for Intracranial Aneurysm Embolization
"Study on the effectiveness and safety of the coil system for the treatment of intracranial aneurysms embolization" was sponsored by Zhuhai Tongqiao Medical Technology Co., Ltd.
- Trial name
- NCT04497181
- Testing
- Coil embolization surgery
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Intracranial Aneurysm
Hemodynamic Analysis for Intracranial Aneurysms Recanalization After Endovascular Treatment
This study was designed to collect a large series of patients with aneurysms treated endovascularly to analyze hemodynamic factors that affect aneurysm recanalization.
- Trial name
- HARET (NCT02812108)
- Testing
- intracranial stent, flow diverter and coils
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Beijing Neurosurgical Institute
Coronary Artery Disease, Arterial Stiffness, Blood Pressure
Expanded Studies on the SCAPIS Stockholm Reexamination Cohort
The Swedish CArdioPulmonary bioImage Study (SCAPIS) is a unique, large-scale national research initiative involving 30,000 randomly selected individuals aged 50-64, recruited between 2014 and 2018.
- Conditions
- Coronary Artery Disease, Arterial Stiffness, Blood Pressure, AORTIC VALVE DISEASES, Mitral Valve Stenosis and/or Insufficiency
- Trial name
- SCAPIS-ReEx (NCT07476703)
- Testing
- Coronary computer tomography (CCTA), Echocardiograhy and aortic ultrasound, Liver elastography
- Where
- Sweden
- Volunteers
- 1,400 people, healthy volunteers welcome
- Sponsor
- Danderyd Hospital
Aortic Aneurysm, Abdominal, Leriche Syndrome
Evaluation of Mechanical Stapler for Aortic Anastomoses
Demonstrate the safety and performance of the Aortic Stapler when used to attach a synthetic graft to an aorta in AAA and Leriche Syndrome patients
- Trial name
- NCT00319475
- Testing
- AAA or AF/IB (end-to-end) in patients with Leriche Syndrome
- Where
- Germany
- Volunteers
- 10 people
- Sponsor
- SVSE 2000 Ltd.
Intracranial Arterial Aneurysm
Analysis Of Intracranial Artery Lesions Using 2-D/3D Phase Contrast MR
Using phase contrast MR Angiography with NOVA® Software, this study intends to identify,evaluate and map intracranial aneurysm development as well as develope a predicator for future morphological changes of aneurysms and…
- Trial name
- NCT00710281
- Testing
- Additional scan time on standard MR angiography
- Where
- United States
- Sponsor
- Lahey Clinic
Cerebral Aneurysm, Trigeminal Neuralgia
EEG Monitoring to Assess Emergence From Neuroanesthesia
A highly desired result in neuroanesthesia is a prompt, controlled emergence following a neurosurgical procedure. Considerable strides have been made in this direction with volatile anesthetic agents such as sevoflurane or…
- Trial name
- NCT00443807
- Testing
- On-line EEG monitoring during neurosurgery, EEGo vs BIS
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- University of Manitoba
CAD - Coronary Artery Disease, CABG
Soft Foam Dressings for Pressure Injury Prevention of Cardiac Surgery
The purpose of this study is to evaluate whether the application of soft foam dressings can reduce the occurrence of surgery-related pressure injuries among patients undergoing cardiac surgery.
- Conditions
- CAD - Coronary Artery Disease, CABG, Valve Disease, Heart, Aortic Diseases
- Trial name
- NCT07379294
- Testing
- CONVAFoam Hydrofiber Dressing, Standard Pressure Injury Prevention Care
- Volunteers
- 80 people
- Sponsor
- Shih,Wen-Chi
Stroke, Thromboses, Intracranial
Stroke Thrombectomy and Aneurysm Registry
This international multi-center registry is used to collect existing information and outcomes for patients undergoing an operation for treatment of injuries to the brain including the blockage of blood flow to an area of the…
- Conditions
- Stroke, Thromboses, Intracranial, Aneurysm, Brain
- Trial name
- STAR (NCT04994756)
- Testing
- Stroke/Thrombectomy/Aneurysm-specific surgical procedures
- Where
- 63 sites in United States, Canada and 7 more
- Volunteers
- 40,000 people
- Sponsor
- Medical University of South Carolina
Intracranial Aneurysms
Treatment of Intracranial Wide-neck Aneurysms Using Stent-assisted Coil Embolization
This device was designed to assist in the stent-assisted coil embolization of intracranial aneurysms, specifically those that have a wide neck that would not otherwise maintain the coil embolization material within the aneurysm…
- Trial name
- NCT04566263
- Testing
- Neuroform EZ Stent System
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Methodist Health System
Randomized Controlled Trial, Intracranial Aneurysm
Comparison of Clipping Via Keyhole Versus Traditional Approaches and Coiling for Ruptured Aneurysms
Endovascular coiling has become a strategy of choice of intracranial aneurysms due to its minimally invasiveness. However, there has few prospective randomized controlled studies on the comparison of therapeutic effect between…
- Conditions
- Randomized Controlled Trial, Intracranial Aneurysm, Microsurgery, Endovascular Procedures
- Trial name
- NCT05049564
- Testing
- keyhole microneurosurgery, conventional microneurosurgery, endovascular coiling
- Volunteers
- 150 people
- Sponsor
- ZhuQing
Craniocerebral Trauma, Intracranial Aneurysm
Hypovitaminosis D in Neurocritical Patients
Vitamin D has been shown to impact prognosis in a variety of retrospective and randomized clinical trials within an intensive care unit (ICU) environment.
- Conditions
- Craniocerebral Trauma, Intracranial Aneurysm, Brain Neoplasms, Spinal Cord Injuries
- Trial name
- NCT02881957
- Testing
- Cholecalciferol
- Where
- United States
- Volunteers
- 274 people
- Sponsor
- University of Utah
Intracranial Aneurysm
Prevalence and Factors Associated With the Occurrence of Depression Six Months After an Endovascular Treatment of Intracranial Aneurysm
During the last decade, the embolization has become the treatment of choice for ruptured intracranial aneurysms, to improve the neurological outcome of patients.
- Trial name
- DEP-AIC (NCT02866812)
- Testing
- questionnaires assessing the state of fatigue, depression and anxiety
- Where
- France
- Volunteers
- 133 people
- Sponsor
- CHU de Reims
Aortic Aneurysm, Thoracic, Penetrating Aortic Ulcers (PAUs)
Evaluation of Thoraflex in the Treatment of Aneurysm or Penetrating Ulcer of the Descending Thoracic Aorta
ThoraflexTM is designed for the treatment of aneurysm or penetrating ulcer of the descending thoracic aorta. Each system is advanced from a transfemoral or transiliac approach over a 0.035" guidewire and positioned under…
- Trial name
- NCT01357590
- Testing
- Thoracic Endovascular Stent Graft System (ThoraflexTM)
- Where
- 28 sites in Belgium, Canada and 5 more
- Sponsor
- Vascutek Ltd.
Acute Coronary Syndrome With ST Elevation on Electrocardiogram, Acute Coronary Syndrome Without ST Elevation on Electrocardiogram
Tryptase and Coronary Heart Disease
The main aim of this study will evaluate differences in serum levels of tryptase in study population. Will be selected a number of 350 patients hospitalized for coronary heart disease.
- Conditions
- Acute Coronary Syndrome With ST Elevation on Electrocardiogram, Acute Coronary Syndrome Without ST Elevation on Electrocardiogram, Noncritical Coronary Artery Disease Coronary Stenosis Less Than 50 Per Cent, Aortic Aneurysms
- Trial name
- NCT01618279
- Where
- Italy
- Volunteers
- 350 people
- Sponsor
- Niguarda Hospital
Intracranial Aneurysms
TransForm™ Occlusion Balloon Catheter Registry
The primary objective of this registry is to collect real world data on the safety and performance of the TransForm™ Occlusion Balloon Catheter when used in current neurointerventional procedures
- Trial name
- NCT01949779
- Testing
- TransForm™ Occlusion Balloon Catheter
- Where
- 7 sites in United States, Spain
- Volunteers
- 81 people
- Sponsor
- Stryker Neurovascular
Intracranial Aneurysm
MicroVention, Inc. Flow Re-Direction Endoluminal Device X (FRED™ X™) Post-Approval Study
The objective of this study is to generate contemporaneous clinical data to facilitate a reasonable comparison of the performance of the FRED™ X™ device with the performance of the FRED™ device.
- Trial name
- NCT05409989
- Testing
- FRED™ X™
- Where
- 23 sites in United States
- Volunteers
- 154 people
- Sponsor
- Microvention-Terumo, Inc.
Ruptured Aneurysm of Intracranial Artery
DIVERT: Diversion of Flow in Intracranial VErtebral and Blood Blister-like Ruptured Aneurysms Trial: A Randomized Trial Comparing Pipeline Flow Diversion and Best-Standard-Treatment
The purpose of the DIVERT study is to provide a prudent, controlled clinical context for the use of flow diversion, a promising option of yet unproven benefit, in the care of patients with acute blood blister-like and dissecting…
- Trial name
- DIVERT (NCT01976026)
- Testing
- Flow Diversion, Best Standard Therapy
- Where
- Canada
- Sponsor
- Centre hospitalier de l'Université de Montréal (CHUM)