Clinical trials: Artery Stenosis
Carotid Artery Plaque, Ischemic Stroke
18F FDG and 68Ga FAPI PET/MR Imaging of Carotid Artery Plaque Vulnerability: A Clinical Study in Carotid Artery Plaque Patients
Carotid atherosclerotic plaque rupture is the main cause of ischemic stroke attacks, and early and precise assessment of plaque vulnerability can prevent ischemic stroke.
- Conditions
- Carotid Artery Plaque, Ischemic Stroke, PET / MR
- Trial name
- NCT07004673
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Ruijin Hospital
Carotid Stenosis
Lifestyle Modification Programme for Patients With Asymptomatic Carotid Artery Stenosis
This study randomises patients with patients with asymptomatic carotid artery stenosis, to be managed either by providing an intensive 12-week lifestyle modification programme, or standard healthcare.
- Trial name
- NCT03929354
- Testing
- Risk Factors Modification Programme, Standard Care
- Where
- Ireland
- Volunteers
- 208 people
- Sponsor
- Western Vascular Institute, Ireland
CAD - Coronary Artery Disease, CABG
Soft Foam Dressings for Pressure Injury Prevention of Cardiac Surgery
The purpose of this study is to evaluate whether the application of soft foam dressings can reduce the occurrence of surgery-related pressure injuries among patients undergoing cardiac surgery.
- Conditions
- CAD - Coronary Artery Disease, CABG, Valve Disease, Heart, Aortic Diseases
- Trial name
- NCT07379294
- Testing
- CONVAFoam Hydrofiber Dressing, Standard Pressure Injury Prevention Care
- Volunteers
- 80 people
- Sponsor
- Shih,Wen-Chi
Healthy, Renovascular Hypertension
Magnetic Resonance Imaging for Evaluating Kidney Function
Renovascular hypertension (RVH) is a potentially curable disease affecting 0.5-5 percent of patients with hypertension. The current diagnostic work-up of RVH involves a complex algorithm which includes doppler ultrasound…
- Trial name
- NCT00006173
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- National Institutes of Health Clinical Center (CC)
Carotid Artery Stenosis, Glioma
Detection of Microplastics and Nanoplastics in Neurosurgery Patients (DT-MiNi)
Plastic particles are a ubiquitous pollutant in the living environment and food chain, so far, plenty of studies have reported the internal exposure of microplastics and nanoplastics in human tissues and enclosed body fluids.
- Conditions
- Carotid Artery Stenosis, Glioma, Intracranial Aneurysm, Intracranial Hemorrhages
- Trial name
- DT-MiNi (NCT05968053)
- Testing
- biological samples analysis
- Where
- China
- Volunteers
- 500 people
- Sponsor
- Beijing Tiantan Hospital
Carotid Stenosis
Co-administration of Dexmedetomidine in Carotid Endarterectomy (CEA)
All neurosurgical patients at the Neurosurgery University Hospital Bern who will be operated for carotid endarterectomy (CEA) are routinely operated in deep anae¬sthesia with suppression of the electrical activity of the…
- Trial name
- NCT04662177
- Testing
- Dexmedetomidine
- Where
- Switzerland
- Volunteers
- 23 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Coronary Artery Disease, Calcified Atheroma
Comparison of Coronary Lithoplasty and Rotablation
This study compares a new method of treating severely calcified coronary lesions, the intracoronary lithoplasty, with the current gold standard, the rotablation.
- Trial name
- NCT04047368
- Testing
- Rotablation, Coronary Lithoplasty
- Where
- Germany
- Volunteers
- 70 people
- Sponsor
- University of Giessen
Intracranial Stenosis
The Predictive Value of Retinal Vascular Signs for Intracranial Artery Stenosis (RVS-ICAS)
Intracranial artery stenosis (ICAS) is a leading cause of ischemic stroke worldwide, contributing to the global burden of stroke, particularly in the Asian population.
- Trial name
- RVS-ICAS (NCT05270746)
- Where
- 2 sites in China
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Capital Medical University
Left Main Coronary Artery Stenosis
eTryton Left Main Registry Tryton Side Branch Stent® Tmt of Denovo CAD in LM and CFX Arteries
The objective of this study is to demonstrate the clinical performance of the Tryton Side Branch Stent used in conjunction with a commercially available Drug Eluting Stent (DES) to treat de novo bifurcated lesions involving both…
- Trial name
- eTRYTONLM (NCT02765646)
- Testing
- Coronary stent procedure (CSP)
- Where
- Germany
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tryton Medical, Inc.
Peripheral Arterial Disease, Peripheral Artery Disease
Digital Variance Angiography in Diagnostic Angiographies for Effective Radiation Dose Reduction
Digital Variance Angiography (DVA) is a new tool in medical imaging with proven image quality reserve. The previously observed quality reserve of Digital Variance Angiography (DVA) in lower extremity angiographies, allowed to…
- Conditions
- Peripheral Arterial Disease, Peripheral Artery Disease, Femoral Artery Stenosis, Femoral Artery Occlusion
- Trial name
- NCT04343196
- Testing
- Diagnostic Angiography (DSA or DVA based on randomization result)
- Where
- Hungary
- Volunteers
- 114 people
- Sponsor
- Kinepict Health Ltd.
Coronary Disease, Coronary Artery Disease
SPIRIT II: A Clinical Evaluation of the XIENCE V® Everolimus Eluting Coronary Stent System
Prospective, randomized, active-control, single blind, parallel two-arm multi-center clinical trial comparing XIENCE V® Everolimus Eluting Coronary Stent System to the approved commercially available active control TAXUS™…
- Conditions
- Coronary Disease, Coronary Artery Disease, Coronary Restenosis
- Trial name
- SPIRIT II (NCT00180310)
- Testing
- XIENCE V® Everolimus Eluting Coronary Stent, TAXUS™ EXPRESS2™ Paclitaxel Eluting Coronary Stent
- Where
- 32 sites in Austria, Belgium and 11 more
- Volunteers
- 300 people
- Sponsor
- Abbott Medical Devices
Pulmonary Stenosis, Pulmonary Regurgitation
Pulmonary Artery Repair With Covered Stents
The Covered Cheatham-Platinum Stent (CCPS) is being study for repair of tears that occur in the pulmonary artery during dilation (enlargement) of a conduit (passageway) connecting the right ventricle of the heart to the pulmonary…
- Conditions
- Pulmonary Stenosis, Pulmonary Regurgitation, Tetralogy of Fallot
- Trial name
- PARCS (NCT01824160)
- Testing
- Repair of RV-PA Conduit Disruption
- Where
- 38 sites in United States
- Volunteers
- 50 people
- Sponsor
- Johns Hopkins University
Apnea+Hypopnea, Tracheal Dilatation
Tracheal Dilatation in Pediatric Patients With Acquired Tracheal Stenosis, and the Effects of Apneic Oxygenation
The study presents an alternative method of tracheal dilatation in pediatric patients with acquired tracheal stenosis. Dilatation is performed by the use of balloon catheter connected with manometer, that is bronchoscopic guided…
- Conditions
- Apnea+Hypopnea, Tracheal Dilatation, Igel, Tracheal Stenosis
- Trial name
- NCT05028023
- Testing
- Apneic oxygenation - supplemental high flow oxygen administration by an apneic way
- Where
- Greece
- Volunteers
- 5 people
- Sponsor
- Aristotle University Of Thessaloniki
Chronic Coronary Syndrome
Computational mOdelliNg of myoCardial pERfusion to Improve ouTcome Prediction Based on cOronary Artery Stenosis and Atherosclerotic Plaque Burden Assessment by Computed Tomography
Detection of coronary stenosis is of utmost importance in identifying vulnerable patients. The combined use of coronary computed tomography angiography at rest (CCTA) and stress myocardial computed tomography perfusion…
- Trial name
- CONCERTO (NCT06337461)
- Where
- Italy
- Volunteers
- 400 people
- Sponsor
- Centro Cardiologico Monzino
Coronary Artery Stenosis
Fractional Flow Reserve and Intravascular Ultrasound in Evaluating Intermediate Coronary Lesions
Recent studies have shown that optimal IVUS criteria defining the functional significance (FFR < 0.8) of intermediate coronary stenoses is different according to their locations of the coronary tree.
- Trial name
- NCT01414361
- Where
- South Korea
- Volunteers
- 1,000 people
- Sponsor
- Seoul National University Hospital
Neurology
Assessment of Plaque Vulnerability Using a Novel Technique: Multi-spectral PhotoAcoustic Imaging.
Identification of intraplaque haemorrhage using MRI is technically demanding and sometimes uncomfortable. Photoacoustic imaging is a new non-invasive technique combining multi-wavelength infrared laser light and ultrasound…
- Trial name
- (CVENT-PAI) (NCT04763603)
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Centre Hospitalier St Anne
Coronary Artery Stenosis
The Real-world Firebird 2 Versus Cypher Sirolimus-eluting Stent in Treating Patients With Coronary Artery Disease
Sirolimus-eluting stent (SES) has been world-widely used in clinical practice in treating patients with coronary artery disease (CAD).
- Trial name
- REFIRE (NCT01328730)
- Testing
- Firebird 2 SES, Cypher SES
- Where
- China
- Volunteers
- 430 people
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Coronary Artery Disease, Coronary Stenosis
SEA-SIDE: Sirolimus Versus Everolimus-eluting Stent Randomized Assessment in Bifurcated Lesions and Clinical SIgnificance of Residual siDE-branch Stenosis
BACKGROUND: Bifurcated lesions are a challenging subset in percutaneous coronary interventions (PCI). The selection of the type of DES and the technique for stent implantation have not been clarified.
- Trial name
- SEA-SIDE (NCT00697372)
- Testing
- Sirolimus eluting stent, Everolimus eluting stent
- Where
- Italy
- Volunteers
- 150 people
- Sponsor
- Catholic University of the Sacred Heart
Carotid Artery Plaque
Photoacoustic Imaging of Atherosclerotic Plaques
Stroke is a major cause of death and disability worldwide. Stenotic carotid arteries can lead to stroke if the cause of the stenosis is a vulnerable atherosclerotic plaque.
- Trial name
- NCT04237064
- Testing
- Photoacoustic imaging
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- Marc van Sambeek
Coronary Artery Disease, Postoperative Complications
Preoperative Intravenous Ferric Carboxymaltose and Placebo in the Treatment of Patients Undergoing Cardiac Surgery
This study evaluates the efficacy and safety of single dose preoperative ferric carboxymaltose in the prevention of postoperative infections and blood transfusions in patients scheduled for cardiac surgery.
- Conditions
- Coronary Artery Disease, Postoperative Complications, Aortic Valve Stenosis, Mitral Valve Disease
- Trial name
- PREFER-CABG (NCT03574311)
- Testing
- Ferric carboxymaltose, Physiological saline
- Where
- Finland
- Volunteers
- 210 people
- Sponsor
- Turku University Hospital
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