Clinical trials: Arthritis, Unspecified
Osteoarthritis, Knee
A Long Term Follow-up Study of Subjects Who Received ICM-203 or Matching Placebo
This is an observational study of the long term safety and efficacy of ICM-203.
- Trial name
- NCT05752032
- Testing
- ICM-203
- Where
- 2 sites in Australia
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- ICM Co. Ltd.
Rheumatoid Arthritis
A Phase III Study of BMS-188667 in Subjects With Active Rheumatoid Arthritis
The purpose of this clinical research study is to learn if abatacept is safe when co-administered with other approved rheumatoid arthritis medications.
- Trial name
- NCT00048932
- Testing
- Double-blind Abatacept, Open-label Abatacept
- Where
- 44 sites in United States
- Volunteers
- 1,795 people
- Sponsor
- Bristol-Myers Squibb
Knee Arthritis
NEUROIMPA - Intraarticular Application of Opioids in Chronic Arthritis of the Knee Joint
To investigate pain and inflammatory parameters (cytokines, immune cells) in knee joint tissue of chronic arthritis patients following intraarticular (i.a.) injections of morphine, a standard steroid or placebo.
- Trial name
- NCT02967302
- Testing
- Morphine Sulfate, Triamcinolone
- Where
- Germany
- Volunteers
- 112 people
- Sponsor
- Hildrun Haibel
Bone Infection, Septic Arthritis
BonE and Joint Infections - Simplifying Treatment in Children Trial
This is a multi- centre trial of children with bone and joint infections (BJIs) at eleven major paediatric hospitals in Australia, New Zealand and Ireland.
- Conditions
- Bone Infection, Septic Arthritis, Bone and Joint Infection, Osteomyelitis
- Trial name
- BEST (NCT04538053)
- Testing
- Oral cefalexin only, IV cefazolin or IV flucloxacillin followed by oral cefalexin
- Where
- 11 sites in Australia, Ireland and 1 more
- Volunteers
- 214 people
- Sponsor
- Murdoch Childrens Research Institute
Rheumatoid Arthritis
Rheumatoid Arthritis Real-world Cohort Study in China (ReALSA)
An ongoing long-term prospective cohort study is conducted by our team, that is dedicated to recruit patients with RA, to identify the development of clinical, biomedical, histopathological and imaging biomarkers for the…
- Trial name
- NCT06233929
- Where
- China
- Volunteers
- 2,000 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Osteoarthritis
Vascular Occlusion in Patients With Osteoarthritis
Resistance exercise plus vascular occlusion may induce greater improvements in strength and muscle mass than resistance training alone.
- Trial name
- NCT01483131
- Testing
- Exercise training, Resistance training with vascular occlusion
- Where
- Brazil
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo
Osteoarthritis, Knee
Alignment Comparison Between TruMatch™ Personalized Solutions and Conventional Total Knee Replacement Instrumentation
This investigation is intended to provide clinical information about alignment using TruMatch™ and to compare the results to a conventional total knee replacement.
- Trial name
- NCT01108237
- Testing
- TruMatch™ Personalized Solutions, Total Knee Arthroplasty with Conventional Instrumentation.
- Where
- 4 sites in United States
- Volunteers
- 78 people
- Sponsor
- DePuy Orthopaedics
Psoriasis, Psoriasis Arthritis
Costa Rican Registry of IL-23 Inhibitors in Psoriatic Disease
The goal of this observational registry study is to evaluate the real-world effectiveness and safety of IL-23 inhibitors in patients with psoriatic disease (psoriasis and/or psoriatic arthritis) treated in Costa Rica.
- Conditions
- Psoriasis, Psoriasis Arthritis, Psoriasis (PsO)
- Trial name
- NCT07448402
- Testing
- Guselkumab (GUS), Risankizumab (RISA)
- Where
- Costa Rica
- Volunteers
- 50 people
- Sponsor
- Caja Costarricense de Seguro Social
Osteoarthritis of the Knee
An Efficacy and Safety Study of Two Doses of Intra-Articular Ampion Injection for Pain of Osteoarthritis of the Knee
This study will evaluate the efficacy of two doses of Intra-Articular Injection of Ampion™ in Adults with pain due to osteoarthritis of the knee.
- Trial name
- NCT01839331
- Testing
- 4 mL injection of Ampion, 10 mL Injection of Ampion
- Volunteers
- 329 people
- Sponsor
- Ampio Pharmaceuticals. Inc.
Osteoarthitis
Evaluating the Role of Genicular Artery Embolization in Treatment of Persistent Pain in Patients With Severe Knee Osteoarthritis
The goal of this randomized clinical trial is to evaluate the role of genicular artery embolization (GAE) in treating persistent pain in patients with severe knee osteoarthritis who have failed conservative treatment and may be…
- Trial name
- NCT07763158
- Testing
- embolization therapy, Conservative treatment
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- King Abdullah International Medical Research Center
Rheumatoid Arthritis
An Observational Study of RoActemra/Actemra in Patients With Moderate to Severe Rheumatoid Arthritis
This open-label, retrospective, observational study will evaluate the compliance to RoActemra/Actemra (tocilizumab) therapy in patients with moderate to severe rheumatoid arthritis.
- Trial name
- NCT01375478
- Where
- 13 sites in Greece
- Volunteers
- 197 people
- Sponsor
- Hoffmann-La Roche
Arthritis
Exploring the Learning Needs of Individuals With Inflammatory Arthritis From the Perspectives of Patients, Family Members and Friends, and Health Care Providers: Patient Perspectives (Focus Groups)
Inflammatory arthritis (IA) is a major cause of long-term disability. Due to specialist shortages, failure of primary care providers and individuals to recognize the disease, and lack of awareness of the importance of early…
- Trial name
- NCT00832676
- Where
- Canada
- Volunteers
- 24 people
- Sponsor
- Sunnybrook Health Sciences Centre
Arthritis, Rheumatoid
The Clinical Efficacy of Immunomodulators in RA Patients
This study includes naive patients and csDMARDs-IR RA patients, treated with different regimens such as Iguratimod combination of different csDMARDs, or csDMARD with TNF inhibitors for 24 weeks.
- Trial name
- NCT05626348
- Testing
- Iguratimod, Methotrexate, Adalimumab Injection
- Where
- China
- Volunteers
- 400 people
- Sponsor
- Qilu Hospital of Shandong University
Medial Knee Compartment Arthritis
Oxford Partial Knee Kinematics Gait Analysis Study
The objective of this study is to compare the effect on gait of unicompartmental knee arthroplasty (UKA), using the Oxford Partial Knee, versus normal knee.
- Trial name
- NCT01454908
- Testing
- Oxford Partial Knee
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- The CORE Institute
Rheumatoid Arthritis
Study of the Effect of Fostamatinib Twice Daily on Blood Pressure in Patients With Rheumatoid Arthritis
The purpose of this study is to evaluate the effect of fostamatinib compared to placebo on ambulatory blood pressure in patients with active rheumatoid arthritis who are taking a disease-modifying anti-rheumatic drug (DMARD).
- Trial name
- Oskira ABPM (NCT01563978)
- Testing
- fostamatinib
- Where
- 56 sites in United States, Bulgaria and 5 more
- Volunteers
- 266 people
- Sponsor
- AstraZeneca
Systemic Lupus Erythematosus, Sjogren's Syndrome
COVID-19 Vaccination in Rheumatic Disease Patients
The research is being done to study the immune responses to COVID-19 vaccination in patients with rheumatic diseases.
- Conditions
- Systemic Lupus Erythematosus, Sjogren's Syndrome, Inflammatory Myositis, Psoriatic Arthritis
- Trial name
- NCT04839315
- Testing
- mRNA COVD19 vaccine
- Where
- United States
- Volunteers
- 58 people
- Sponsor
- Mayo Clinic
Arthritis, Rheumatoid, Spondylitis, Ankylosing
C.O.R.P.U.S.: Observational Cohort of Adult and Child Inflammatory Arthritis in France
C.O.R.P.U.S. is the first French observatory of care practices in active inflammatory rheumatism of children and adults: rheumatoid arthritis, spondylarthropathy, and idiopathic juvenile arthritis, established under the auspices…
- Conditions
- Arthritis, Rheumatoid, Spondylitis, Ankylosing, Arthritis, Psoriatic, Arthitis, Juvenile Idiopathic
- Trial name
- NCT02886689
- Testing
- TNF-alpha antagonist and other biotherapy
- Where
- France
- Volunteers
- 5,400 people
- Sponsor
- Central Hospital, Nancy, France
Arthritis, Rheumatoid
A Study To Investigate And Describe The Treatment Patterns And Effect Of Tofacitinib Indicators For Patients With Rheumatoid Arthritis
This study is to investigate and describe the treatment patterns and effect of tofacitinib indicators for patients with Rheumatoid Arthritis (RA) assessing real world patient data entered in the Corrona RA Registry on or after…
- Trial name
- NCT04721808
- Where
- United States
- Volunteers
- 1,712 people
- Sponsor
- Pfizer
Rheumatoid Arthritis
Evaluation of Pain Sensitization in Rheumatoid Arthritis: Analysis on a Cohort of Tofacitinib Treated Patients
Persistent pain and chronic fatigue are very common complaints in rheumatoid arthritis (RA) patients, whatever the anti-inflammatory treatment response.
- Trial name
- TOPRA (NCT03815578)
- Testing
- Clinical examination, Pain assessment, blood sample
- Where
- 2 sites in France
- Volunteers
- 20 people
- Sponsor
- University Hospital, Bordeaux
Osteoarthritis of Knee
Effect of Video-based Game and Aerobic Exercise on Knee Osteoarthritis
This randomized controlled trial was conducted by the CONSORT guidelines for non-pharmacological treatments. Participants were randomly assigned to control, gaming, or aerobic groups using the closed-envelope randomization…
- Trial name
- NCT06885008
- Testing
- Active video game, Aerobic exercise, Conventional treatment
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Hasan Kalyoncu University
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