Clinical trials: Arthropathy of Knee
Patellofemoral Pain Syndrome, Anterior Knee Pain Syndrome
Clinical Comparison of Patellofemoral Pain Syndrome Outcomes After Blood Flow Restriction Therapy
The purpose of this study is to determine if Blood Flow Restriction therapy improves patient related outcomes in those diagnosed with Patellofemoral Pain Syndrome compared to those in the sham comparator control group.
- Trial name
- NCT05617911
- Testing
- Blood Flow Restriction Cuff
- Where
- 6 sites in United States
- Volunteers
- 1 people
- Sponsor
- Gaylord Hospital, Inc
Knee Injuries, Knee Osteoarthritis
Gait Modification Treatments for Knee Pathology
The objective of this study is complete a longitudinal cross-over clinical study to investigate the effect of treatments for knee pathology, including cutaneous stimulation (skin vibration and soft knee brace), on locomotion…
- Trial name
- NCT03116230
- Testing
- Cutaneous Stimulation, Knee Sleeve
- Where
- United States
- Volunteers
- 38 people
- Sponsor
- Stanford University
Knee Osteoarthritis
The Effects of Specialized Footwear in Osteoarthritis
This study evaluates the effects of specialized footwear on pain and knee loading in knee osteoarthritis. The hypothesis is that this footwear will lead to decreased knee loading and knee pain.
- Trial name
- NCT01597830
- Testing
- Mobility shoe, control shoe
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Rush University Medical Center
Osteoarthritis, Knee
Effects of Including Interferential Current in a Therapeutic Exercise Program in Individuals With Knee Osteoarthritis
The first-line treatment for knee osteoarthritis (KOA) in terms of pain and functionality is physical exercise. The use of interferential current (IC) associated with other resources may be beneficial in reducing pain intensity…
- Trial name
- NCT06744036
- Testing
- Therapeutic Exercise, Interferential Current
- Where
- Brazil
- Volunteers
- 138 people
- Sponsor
- University of Nove de Julho
Osteoarthritis,Knee
NSAID Treatment of Patients With Osteoarthritis
The study investigates associations between pre treatment pain intensity and central pain mechanisms on the effect of 8-week treatment of NSAIDs in patients with knee osteoarthritis.
- Trial name
- NCT02967744
- Testing
- NSAID
- Where
- Denmark
- Volunteers
- 162 people
- Sponsor
- Aalborg University
Knee Arthropathy
Comparison of Balance and Fall Risk in Unilateral and Bilateral Total Knee Arthroplasty
Static or dynamic postural control cannot be fully restored in patients with Total Knee Arthroplasty (TKA). Moreover, deficits in balance and postural control may still be present in both extremity after TKA.
- Trial name
- NCT04796519
- Testing
- Total knee arthroplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Pamukkale University
Osteoarthritis, Knee
CONNACT OA Knee Cohort
CONNACT OA knee cohort is a prospective longitudinal cohort study where we aim to collect sociodemographic, psychosocial, clinical, health utilization and cost data in order to better understand the Asian OA knee cohort and…
- Trial name
- CONNACT (NCT04942236)
- Where
- 3 sites in Singapore
- Volunteers
- 500 people
- Sponsor
- Tan Tock Seng Hospital
Osteo Arthritis Knee, Osteoarthritis
Comparison of Alignment Achieved Using the VELYS Robotic-Assisted Solution Versus Manual Instrumentation in Total Knee Arthroplasty
The purpose of this post-market research study is to gather clinical and radiographic (X-ray) information about total knee replacement surgeries completed with the VELYS Robotic-Assisted Solution and with standard manual…
- Trial name
- NCT04730271
- Testing
- Total Knee Replacement
- Where
- 5 sites in United States
- Volunteers
- 200 people
- Sponsor
- DePuy Orthopaedics
Patella Dislocation
Outcome After Soft Tissue Realignment of the Tibial Insertion of the Patella Tendon
Soft tissue realignment of the tibial insertion of the patella tendon is a simple operative technique for treating dislocation of the patella in childhood and adolescence.
- Trial name
- NCT01059721
- Testing
- Medialising insertion of patella tendon
- Volunteers
- 43 people
- Sponsor
- Medical University of Graz
Osteoarthritis of the Knee or Hip
Long-Term Safety and Efficacy Study of Fasinumab in Patients With Pain Due to Osteoarthritis (OA) of the Knee or Hip
The primary objective of the study is to describe the safety and tolerability of fasinumab, including adverse events of special interest (AESIs), in patients with pain due to radiographically-confirmed OA of the knee or hip.
- Trial name
- FACT LTS & OA (NCT02683239)
- Testing
- Fasinumab
- Where
- 149 sites in United States, Bulgaria and 19 more
- Volunteers
- 5,331 people
- Sponsor
- Regeneron Pharmaceuticals
Obesity, Knee Osteoarthritis (OA)
A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
The purpose of this clinical study is to find out if NNC0487-0111 is safe and effective for treating people who have excess body weight and knee osteoarthritis.
- Trial name
- AMAZE 5 (NCT07481630)
- Testing
- NNC0487-0111
- Where
- 82 sites in United States, Australia and 8 more
- Volunteers
- 400 people
- Sponsor
- Novo Nordisk A/S
Knee Osteoarthritis
Navigation System for in Vivo Measurement of the Kinematics of the Knee
The knee prosthesis is a validated treatment for end-stage osteoarthritis, and this intervention usually provides a significant improvement in the quality of life of patients.
- Trial name
- NCT02467699
- Where
- France
- Volunteers
- 40 people
- Sponsor
- University Hospital, Strasbourg, France
Osteoarthritis of the Knee
A Study of ARRY-371797 in Patients With Osteoarthritis of the Knee
This is a Phase 2 study, involving a 4-week treatment period, designed to test the ability of investigational study drug ARRY-371797 to reduce pain in patients with moderate to severe pain due to osteoarthritis (OA) of the knee…
- Trial name
- NCT01366014
- Testing
- ARRY-371797, p38 inhibitor; oral, Oxycodone hydrochloride (HCl) extended release (ER), opioid agonist; oral
- Where
- 13 sites in United States
- Volunteers
- 157 people
- Sponsor
- Pfizer
Osteoarthritis
DSJ-2016-07 ATTUNE® Cementless CR RP Japan
The primary objective is to investigate the change from pre-operative baseline to two year postoperative functional performance improvement for the ATTUNE® primary, cementless TKA RP system as measured with the KOOS questionnaire…
- Trial name
- NCT03193034
- Testing
- Cementless Total Knee Arthroplasty
- Where
- 4 sites in Japan
- Volunteers
- 81 people
- Sponsor
- DePuy Orthopaedics
Knee Osteoarthritis
The Effect of Neuromuscular Training on Osteoarthritis: A Comparative Prospective Randomized Study
Context: The many treatments and devices developed to unload the diseased articular surface in knee osteoarthritis have provided limited solutions.
- Trial name
- NCT00457132
- Testing
- APOS biomechanical gait system
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Assaf-Harofeh Medical Center
Anesthesia, Knee Osteoarthritis
The Assessment of Postoperative Recovery in Elder Diabetic Patients
Total Knee Replacement (TKR) performed under general anesthesia is a common successful orthopedic procedure. Nonetheless, in elder patients with diabetes mellitus (DM) this procedure can present unique challenges to orthopedic…
- Trial name
- TKRDM2013 (NCT01871012)
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Chinese PLA General Hospital
Osteoarthritis
A Migration and Bone Density Study Comparing 2 Types of Bone Cement in the OptiPac Bone Cement Mixing System
The goal of this scientific study is to determine whether there are differences in early migration and prosthesis-near bone density when a standard knee prosthesis is fixed with Refobacin Bone Cement R or with Refobacin Plus Bone…
- Trial name
- NCT00678236
- Testing
- Refobacin Bone Cement R, Refobacin Plus Bone Cement
- Where
- Denmark
- Volunteers
- 54 people
- Sponsor
- University of Aarhus
Knee Osteoarthritis, Type II Diabetes
Burger Allen Exercises in Knee OA With Type II Diabetes
There is a potential link between diabetes mellitus (DM) and severity of osteoarthritis .Type 2 diabetes is a part of the metabolic syndrome (Mets) accompanied by ageing and mechanical stress are also a risk factor to…
- Trial name
- NCT05878587
- Testing
- thermotherapy+ TENS+ low intensity high repetition exercises and Buerger Allen, thermotherapy+ TENS+ low intensity high repetition exercises
- Where
- Pakistan
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Osteoarthritis, Knee
Efficacy and Safety of Intraarticular Sodium Hyaluronate Single Injection in Patients With Osteoarthritis of the Knee
A Phase III, prospective, multicentre, non-controlled, with consecutive participant enrollment in order to evaluate the efficacy, safety and duration of the effects of the viscosupplementation with a preparation of sodium…
- Trial name
- NCT03852914
- Testing
- Sodium hyaluronate 2%
- Where
- 10 sites in Spain
- Volunteers
- 93 people
- Sponsor
- Tedec-Meiji Farma, S.A.
Patellofemoral Pain Syndrome
Tele-rehabilitation for Recreational Athletes With Patellofemoral Pain Syndrome
This study is a randomized clinical trial designed to evaluate the usability and effectiveness of a tele-rehabilitation program in recreational athletes with Patellofemoral Pain Syndrome (PFPS).
- Trial name
- NCT07693634
- Testing
- Conventional Physical Therapy, Tele-rehabilitation
- Where
- Pakistan
- Volunteers
- 26 people
- Sponsor
- University of Faisalabad
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.