Clinical trials: Ascorbic Acid
Stage IV Pancreatic Cancer
Assessing the Efficacy and Safety of IV Vitamin C in Combination With Standard Chemotherapy for Pancreatic Ca
The investigators recently completed a phase I study of intravenous ascorbic acid (IV AA) plus standard chemotherapy (gemcitabine and erlotinib) in patients with metastatic pancreatic cancer.
- Trial name
- NCT01555489
- Testing
- Ascorbic Acid
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- Thomas Jefferson University
Depigmentation Treatment, Depigmentation
Effect of Co-enzyme Q10 and Vitamin C Alone or in Combination After a Surgical Gingival Depigmentation
This study aims to assess the clinical effectiveness of Co-enzyme Q10 and Vitamin C, applied individually or in combination after surgical gingival depigmentation.
- Trial name
- Effect of Coe (NCT07677826)
- Testing
- surgical depigmentation, Coenzyme Q10, Vitamin C
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Cardiac Arrest
Vitamin C in Post-cardiac Arrest
Only half of the patients suffering from cardiac arrest arrive at the hospital alive. Of these survivors, more than 50% will still die or remain severely disabled.
- Trial name
- VITaCCA (NCT03509662)
- Testing
- Vitamin C, Thiamine
- Where
- Netherlands
- Volunteers
- 270 people
- Sponsor
- Amsterdam UMC, location VUmc
Infections, Respiratory Tract
An Efficacy and Safety Study of Theraflu Night Powder as Oral Solution for Cold and Flu
The purpose of the study is to assess the short term efficacy of the Theraflu Night powder for oral solution in the Russian population in "Short term relief of the symptoms of colds, chills and influenza, including mild to…
- Trial name
- NCT02730364
- Testing
- Paracetamol, phenylephrine HCl, pheniramine maleate, and vitamin C
- Sponsor
- GlaxoSmithKline
Stasis; Colon
Comparison Between Coolprep and Picolyte for Bowel Cleansing
The investigators will compare with PEG+ascorbic acid and picosulfate+magnesium citrate about bowel preparation, patient's satisfaction, side effects to identify effectiveness of new bowel preparation drug.
- Trial name
- NCT01774175
- Volunteers
- 250 people
- Sponsor
- Gachon University Gil Medical Center
Myelodysplastic Syndromes and Leukemia, Myeloid, Acute
Decitabine, Arsenic Trioxide and Ascorbic Acid for Myelodysplastic Syndromes and Acute Myeloid Leukemia
This study is designed to test the combination of decitabine, arsenic trioxide and ascorbic acid in patients with myelodysplastic syndromes (MDS) and acute myeloid leukemia
- Trial name
- NCT00671697
- Testing
- Arsenic Trioxide, Decitabine
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Washington University School of Medicine
Interventional
The Effect of Exercise and Presleep Nutrition on Muscle Connective Tissue Remodelling
The primary objective of this study will be to determine the influence of a presleep vitamin C-enriched, collagen-modelled supplement (CVC) on the metabolic fate of dietary glycine using a [2H5]glycine tracer within the…
- Trial name
- NCT06054620
- Testing
- Collagen and Vitamin C
- Where
- Canada
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Stage II Multiple Myeloma, Stage III Multiple Myeloma
Melphalan, Arsenic Trioxide, and Ascorbic Acid in Treating Patients With Relapsed or Refractory Multiple Myeloma
RATIONALE: Drugs used in chemotherapy, such as melphalan, arsenic trioxide, and ascorbic acid, work in different ways to stop cancer cells from dividing so they stop growing or die.
- Conditions
- Stage II Multiple Myeloma, Stage III Multiple Myeloma, Refractory Plasma Cell Neoplasm
- Trial name
- NCT00085345
- Testing
- arsenic trioxide, ascorbic acid, melphalan
- Where
- 19 sites in United States
- Sponsor
- Oncotherapeutics
Fatigue
Intravenous Ascorbic Acid in Women Receiving Adjuvant or Neo-Adjuvant Chemotherapy for Early Stage Breast Cancer
This is a parallel-track, randomized study will observe whether intravenous ascorbic acid reduces the reported fatigue in women receiving adjuvant or neo-adjuvant chemotherapy for early stage breast cancer.
- Trial name
- NCT02521077
- Testing
- Ascorbic Acid, Normal Saline
- Sponsor
- Midwestern Regional Medical Center
Hypoxic Ischemic Encephalopathy, Perinatal Asphyxia
Ascorbic Acid and Ibuprofen in Infants With Hypoxic Ischemic Encephalopathy
Oxygen radicals and inflammation are important causes for brain injury in neonates following perinatal asphyxia. Animal studies demonstrated potential benefits to the brain when using both of vitamin C and ibuprofen.
- Trial name
- NCT00624871
- Testing
- Ascorbic acid (vitamin C), Ibuprofen
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Al-Azhar University
Kidney Stone
Oxalate Formation From Ascorbic Acid
The purpose of this basic research study is to determine the contribution of endogenous ascorbic acid (AA) turnover to urinary oxalate excretion in both normal BMI and obese adult non-stone formers and calcium oxalate stone…
- Trial name
- NCT04603898
- Testing
- Low Oxalate Diet, Carbon-13 Ascorbic Acid Oral Load
- Where
- United States
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Septic, Acute Respiratory Distress Syndrome
Lessening Organ Dysfunction With VITamin C in Septic ARDS
The primary objective of the study aims to compare the effect of high-dose intravenous vitamin C vs. placebo on a composite of death or persistent organ dysfunction - defined as continued dependency on mechanical ventilation, new…
- Trial name
- LOVIT ARDS (NCT04404387)
- Testing
- Administration of vitamin C
- Where
- France
- Volunteers
- 800 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Diabetes Mellitus, Non-Insulin Dependent, Non-Insulin Dependent
Study of the Effects of Vitamin C on Patients With Type 2 Diabetes
Diabetes is a disease characterized by decreased sensitivity to the action on insulin to promote sugar (glucose) use and blood vessel relaxation (vasodilation) in muscle.
- Trial name
- NCT00001870
- Testing
- Acetylcholine
- Where
- United States
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Obstetric Labor Complications, Fever
Effect of Intravenous Vitamin C on Intrapartum Maternal Fever After Epidural Labor Analgesia
This study aims to explore the effect of intravenous vitamin C infusion on intrapartum fever after epidural labor analgesia, to reduce the impact of intrapartum fever on maternal and infant, improve maternal and infant outcomes…
- Trial name
- EIVCIMFAELA (NCT06354582)
- Testing
- Vitamin C Injection, Normal saline
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Kunyue Li
Cardio-pulmonary Bypass, Cardiovascular Diseases
Dietary Supplements in Patients With Coronary Artery Bypass Grafting for Improving the Quality of Healthcare Delivery.
Cardiovascular disease (CVD) remains the leading cause of death worldwide. Prevention of CAD by targeting modifiable factors remains a key public health priority. L-Ascorbic Acid (Vitamin C - Vit.
- Conditions
- Cardio-pulmonary Bypass, Cardiovascular Diseases, Omega-3 Polyunsaturated Fatty Acids, Omega-3 Supplementation
- Trial name
- NCT06995586
- Testing
- Vitamin C, Omega 3 PUFA (EPO/DHA), Lignin, Lactulose
- Where
- Cyprus
- Volunteers
- 108 people
- Sponsor
- Nicosia General Hospital
ARDS
Vitamin C Versus Nitric Oxide in Prolonged Ventilation
This a prospective double-blind study done in King Abdul-Aziz specialist hospital between January 2019 and April 2020 in the intensive care unit on 60 patients with difficult weaning and ventilated for 10 days.
- Trial name
- NCT04411160
- Testing
- Vitamin C, Nitric Oxide, ventilators
- Where
- Saudi Arabia
- Volunteers
- 60 people
- Sponsor
- King Abdul Aziz Specialist Hospital
Lateral Epicondylitis, Tennis Elbow
Efficacy of Vitamin C Supplement vs Spinal Manipulation to Treatment in Lateral Epicondylitis
A randomized clinical trial will be conducted. 130 subjects diagnosed with lateral epicondylitis will be studied. 3 intervention groups will be formed.
- Trial name
- NCT04445727
- Testing
- Vitamin C, spinal manipulation, Transcutaneous electrical nerve stimulation (TENS)
- Where
- Spain
- Volunteers
- 130 people
- Sponsor
- Universidad Rey Juan Carlos
Iron-deficiency
Measuring Dietary Iron Absorption From Edible Insects and Assessing the Effect of Chitin Content on Iron Bioavailability (Study 2)
Due to the growing world population, there is a need to develop viable ecological and nutritional alternatives to animal food products.
- Trial name
- Sustironable2 (NCT05328141)
- Testing
- Bread and butter, X.gideon, X.gideon with ascorbic acid
- Where
- Switzerland
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- Swiss Federal Institute of Technology
Catheter-Associated Urinary Tract Infection, Ascorbic Acid
Vitamin C for the Prevention of UTI in Women Who Undergo Elective GYN Surgeries
This open-label randomized trial aims at assessing the role of Vitamin C pills in the prevention of catheter-associated urinary tract infections in women undergoing elective gynecological surgeries.
- Trial name
- NCT03800667
- Testing
- Ascorbic Acid 1000 MG
- Where
- Lebanon
- Sponsor
- American University of Beirut Medical Center
Enterocutaneous Fistulas
Vitamin C and Zinc in Patients With Enterocutaneous Fistulas.
Various micronutrients play an important role in the process of closure and recurrence of enterocutaneous fistulas, such as Vitamin C and Zinc.
- Trial name
- VITAC (NCT06009744)
- Testing
- Low-dose vitamin C and zinc, High-dose vitamin C and zinc
- Where
- Mexico
- Volunteers
- 76 people
- Sponsor
- Hospital Juarez de Mexico