Clinical trials: Aspiration
Anesthesia, Aspiration
How do You Take Your Coffee Before Anesthesia
Undergoing anesthesia requires patients to fast pre-operatively to allow the stomach to empty and prevent aspiration pneumonia but patients are allowed to drink "clear" liquids up to 2 hours before surgery.
- Conditions
- Anesthesia, Aspiration, Fasting
- Trial name
- NCT04786691
- Testing
- Addition of half and half to coffee, Addition of non-dairy creamer to coffee, Black
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Breast Cancer
LY353381 in Preventing Breast Cancer in Women With Hyperplasia
RATIONALE: Chemoprevention therapy is the use of certain drugs to try to prevent the development or recurrence of cancer. The use of LY353381 may be an effective way to prevent the development of breast cancer in women who have…
- Trial name
- NCT00005879
- Testing
- arzoxifene
- Where
- 2 sites in United States
- Volunteers
- 199 people, healthy volunteers welcome
- Sponsor
- University of Kansas Medical Center
Chronic Dysphagia, Multiple Sclerosis
A Comparison of an Implanted Neuroprosthesis With Sensory Training for Improving Airway Protection in Chronic Dysphagia
This study will compare an implant with the technique of sensory training to determine which method may improve the ability to swallow and reduce the risk of choking.
- Conditions
- Chronic Dysphagia, Multiple Sclerosis, Parkinson Disease
- Trial name
- NCT00376506
- Testing
- Neurostimulation device for dysphagia, External vibrotactile device
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Post-ERCP Acute Pancreatitis
Rectal Indomethacin to Prevent Post-Endoscopic Retrograde Cholangiopancreatography (ERCP) Pancreatitis
The purpose of this study is to assess whether peri-procedural administration of rectal indomethacin, compared to placebo, can reduce the incidence of post-ERCP pancreatitis.
- Trial name
- NCT01774604
- Testing
- Indomethacin
- Where
- United States
- Volunteers
- 449 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
Asthma in Children, Pollution; Exposure
AIM to Improve Asthma: Airflow Improvements During Meal-Prep
The investigators propose a pilot trial of kitchen ventilation in the homes of children using a youth engaged research strategy.
- Trial name
- AIM (NCT04464720)
- Testing
- Cooking Ventilation Intervention
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- University of California, Berkeley
Upper Airway Obstruction
Phamacological Reversal of Airway Instability During Sedation
The investigators are attempting to demonstrate a decrease in the frequency and severity of sedation-induced respiratory arrhythmias(central and obstructive apneas) with pharmacological pre-treatment in this pilot project and…
- Trial name
- PHYSO (NCT01171118)
- Testing
- Physostigmine, Oxygen
- Where
- United States
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- University of Rochester
Healthy Volunteers
Relative Bioavailability Study to Compare Inhalation of Terbutaline Sulphate 1,5mg Via Turbuhaler M3 With Turbuhaler M2
Relative bioavailability study to compare inhalation of Terbutaline Sulphate 1,5mg via current version of Turbuhaler with inhalation via a new version
- Trial name
- NCT02178059
- Testing
- terbutaline sulphate delivered dose, terbutaline sulphate metered dose
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- AstraZeneca
Adult Subject
Effect of Super-Oxygenated Water on Blood Oxygen Saturation
Therapeutic delivery of additional Oxygen to blood stream via hyperbaric and extracorporeal oxygenation that raises blood Oxygen saturation level, apart from oxygenation in the lungs, is known to induce tissue repair, restore…
- Trial name
- NCT07016191
- Testing
- Ingestion of Water
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Inhale, Inc
Infertility
Aspiration of Limited Number of Follicles to Prevent Severe Ovarian Hyperstimulation Syndrome
The purpose of this study is to evaluate the effect of single ovarian puncture to retrieve 7eggs only in prevention of severe ovarian hyperstimulation syndrome.
- Trial name
- NCT02635425
- Testing
- 7 eggs collection, Full eggs collection
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Ahmad Hussieny Salama
Parkinson's Disease
Long-term Effect of Low Frequency Stimulation on Aspiration and Freezing of Gait in PD With STN DBS
Our recent study (Xie et al, Neurology 2015; 84: 415-420) found that bilateral STN DBS of 60Hz, compared to the traditional 130Hz, decreased the aspiration frequency and swallowing difficulty, freezing of gait (FOG), and other…
- Trial name
- NCT02549859
- Testing
- Deep Brain Stimulation (DBS) at 60 Hz, Deep Brain Stimulation (DBS) at 130 Hz
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Chicago
Kidney Stone, Renal Stone
Comparison of Laser Lithotripsy With and Without Steerable Ureteroscopic Renal Evacuation (SURE)
The purpose of the study is to compare the effects, good and/or bad, of a treatment for removing kidney stones called the SURE procedure for stone evacuation to the standard treatment using a basket for stone removal.
- Conditions
- Kidney Stone, Renal Stone, Urolithiasis
- Trial name
- NCT04519294
- Testing
- SURE, Standard Ureteroscopy (Basketing)
- Where
- 11 sites in United States
- Volunteers
- 132 people
- Sponsor
- Calyxo, Inc.
Breast Cancer Diagnosis
Automated Method for Breast Cancer Detection
Participants with suspicious breast lesions by mammography will undergo fine needle aspiration (FNA) under ultrasound guidance. The FNA will be read by the cytopathologist and analyzed in the breast cancer detection cartridge.
- Trial name
- NCT03863522
- Testing
- Fine needle aspiration, Cancer Detection cartridge
- Where
- 2 sites in United States
- Volunteers
- 116 people
- Sponsor
- Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins
Aspiration Pneumonia
Functionality and Accuracy of the smART System in Real-Life ICU Settings
Total participants in the "Functionality and Accuracy of the smART System in Real-Life ICU Settings" are 10 participants - in the current Jefferson study site there were 8 participants and in the Sheba study site (identifier…
- Trial name
- NCT03198988
- Testing
- smART Feeding Tube System
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- ART Medical Ltd.
Pulmonary Arterial Hypertension
Study of Incidence of Respiratory Tract AEs in Patients Treated With Tyvaso® Compared to Other FDA Approved PAH Therapies
A surveillance of respiratory tract related adverse events in patients treated with Tyvaso®(treprostinil) Inhalation Solution versus other FDA approved therapies
- Trial name
- Aspire (NCT01266265)
- Testing
- inhaled prostacyclin, prostacyclin, subcutaneous and intravenous prostacyclin
- Where
- 88 sites in United States
- Volunteers
- 1,333 people
- Sponsor
- United Therapeutics
Upper Airway Obstruction, Respiratory Insufficiency
Astral VAPS AutoEPAP Clinical Trial
Patients with chronic respiratory failure such as those associated with Chronic Obstructive Pulmonary Disease (COPD), Obesity Hypoventilation Syndrome (OHS), Obstructive Sleep Apnea (OSA) or Neuromuscular Disease (NMD) are…
- Conditions
- Upper Airway Obstruction, Respiratory Insufficiency, Respiratory Failure
- Trial name
- NCT02683772
- Testing
- Astral
- Where
- 5 sites in United States
- Volunteers
- 42 people
- Sponsor
- ResMed
Pain
Buffered Lidocaine in Paracervical Blocks
For pain relief during a first trimester surgical aspiration, most providers use the paracervical block, either alone or in combination with other pain control techniques.
- Trial name
- NCT03107754
- Testing
- Lidocaine, Lidocaine-Sodium Bicarbonate
- Where
- United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- University of Hawaii
Ventilation, Reproducibility
Assessing Variability of the Ventilatory Response to Duffin's Rebreathing Procedure
This study will combine Duffin's rebreathing procedure with additional study procedures, such as quantitative pupillometry, that are planned for subsequent clinical studies in order to confirm feasibility and gather…
- Conditions
- Ventilation, Reproducibility, Physiology
- Trial name
- NCT05168501
- Testing
- Rebreathing procedure
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Food and Drug Administration (FDA)
Electric Stimulation, Respiration, Artificial
Breath Synchronized Abdominal Muscle Stimulation to Facilitate Ventilator Weaning: a Pilot Study
The primary objective of this study is to determine whether neuromuscular electrical stimulation applied to the abdominal wall muscles in synchrony with exhalation can increase the strength of the respiratory muscles in prolonged…
- Conditions
- Electric Stimulation, Respiration, Artificial, Ventilator Weaning
- Trial name
- NCT03019107
- Testing
- Breath synchronized abdominal NMES
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Liberate Medical
Acute Ischemic Stroke
Prospective Evaluation to Characterize the Real-World Performance of the EMBOVAC Aspiration Catheter
A post-market study evaluating the EMBOVAC Aspiration Catheter in acute ischemic stroke patients with confirmed intracranial large vessel occlusion.
- Trial name
- PERFECT (NCT04531904)
- Testing
- EMBOVAC Aspiration Catheter
- Where
- 2 sites in Germany, United Kingdom
- Volunteers
- 102 people
- Sponsor
- Cerenovus, Part of DePuy Synthes Products, Inc.
Ischemic Stroke, Acute Stroke
The Imperative Trial: Treatment of Acute Ischemic Stroke With the Zoom Reperfusion System
The trial is designed to assess the safety and efficacy of using the Zoom Reperfusion System in subjects diagnosed with acute ischemic stroke and undergoing a thrombectomy procedure within 8 hours of last known well.
- Trial name
- NCT04129125
- Testing
- Zoom Reperfusion System
- Where
- 28 sites in United States
- Volunteers
- 328 people
- Sponsor
- Imperative Care, Inc.