Clinical trials: Assessment of Recovery
Stroke
Role of Ipsilateral Motor Cortex in Executing Movements With Increasing Demand on Precision
It is well known that the motor area of one hemisphere of the brain (motor cortex) controls the movement of the opposite of the body.
- Trial name
- RIMC (NCT01726218)
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cathrin Buetefisch
Postoperative Pain
Evaluation of the Efficacy of Sublingual Sufentanil (Prescribed as Rescue Analgesia for Acute Postoperative Pain) on the Quality of Health Recovery After Surgery: a Randomized, Controlled, Multicenter, Open-label Trial Against an Active Comparator (SUBLIME)
The number of surgical procedures performed annually exceeds 300 million worldwide and continues to grow. The management of the most common perioperative symptoms (pain, nausea/vomiting, constipation) represents a major public…
- Trial name
- SUBLIME (NCT07624006)
- Testing
- Sublingual sufentanil 30 µg (one dose per hour, as needed), Morphine sulfate (10 mg every 4 hours as needed)
- Where
- France
- Volunteers
- 1,150 people
- Sponsor
- University Hospital, Strasbourg, France
Healthy, Sports Physical Therapy
The Effect of Vagus Nerve Stimulation on Cycling Ergometry and Recovery
It is aIt is aimed to examine the possible benefits and effects of the use of Transcutaneous Auricular Vagus Nerve Stimulation to be applied in healthy individuals for sportive purposes on recovery and sportive performance level.
- Conditions
- Healthy, Sports Physical Therapy, Activity, Motor
- Trial name
- TAVNSCER (NCT05778058)
- Testing
- Unilateral Stimulation, Bilateral Stimulation, Bicycle Ergometer Test
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Sinop University
Covid19, SARS-CoV Infection
A Registry Study of COVID-19 Serologic and Virologic Testing to Accelerate Recovery and Transition
The co-primary objectives of this study are to: 1. Determine and compare the COVID-19 antibody positivity rate in health care workers and patients without a known COVID-19 infection 2.
- Trial name
- START (NCT04573634)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Jill M Kolesar
Athletic Performance, Cognitive Fatigue
TCP-600 Supplementation and Performance Response in Professional Football Players
This study will examine whether a 28-day supplementation protocol containing taurine, caffeine, and phosphatidylserine can help professional male football players maintain physical performance, cognitive function…
- Conditions
- Athletic Performance, Cognitive Fatigue, Exercise Recovery, Football-Specific Performance
- Trial name
- TCP600-RESP (NCT07710547)
- Testing
- Taurine, Caffeine, Phosphatidylserine
- Where
- 3 sites in Poland
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Vizja University in Warsaw
Enhanced Recovery After Surgery
Safety and Efficacy of TU-100 as an Adjunct to an Enhanced Recovery After Surgery in Subjects Undergoing Bowel Resection
This multicenter, randomized, double-blinded, placebo-controlled study will evaluate the effect of TU-100 on resolution of postoperative ileus (POI) in subjects undergoing open or laparoscopic bowel resection (BR).
- Trial name
- NCT04742907
- Testing
- TU-100
- Where
- 36 sites in United States
- Volunteers
- 402 people
- Sponsor
- Tsumura USA
Neuromuscular Blockade
Evaluation of the Tof Cuff for Perioperative Neuromuscular Transmission
Acceleromyography (AMG) is the most wide spread used method to assess neuromuscular block during anesthesia. However AMG is known to be inaccurate when compared to the gold standard in neuromuscular transmission monitoring…
- Trial name
- NCT03117387
- Testing
- Measurements of the level of neuromuscular blockade
- Where
- 2 sites in Netherlands
- Volunteers
- 250 people
- Sponsor
- Leiden University Medical Center
Liver Transplantation
Study to Evaluate Performance of the Organ Recovery Systems LifePort® Liver Transporter System, a Machine Perfusion System, for Liver Transplant
Comparison of hypothermic machine perfusion of livers to standard of care (static cold storage).
- Trial name
- PILOT™ (NCT03484455)
- Testing
- Hypothermic machine perfusion, Static cold storage
- Where
- 9 sites in United States
- Volunteers
- 142 people
- Sponsor
- Organ Recovery Systems, Inc.
Delirium
Clinical Investigation of an Eye-Tracking Device as a Predictor of Delirium in the Recovery Room After Surgery With General Anesthesia
Neurotrack™ is an FDA-approved device for measuring and tracking cognitive decline, as may occur with age-related cognitive decline and Alzheimer's disease.
- Trial name
- NCT05579093
- Testing
- Cognitive test + Pupillary measure
- Where
- United States
- Volunteers
- 325 people, healthy volunteers welcome
- Sponsor
- Columbia University
Healthy Volunteers
Transfusion of Biotin-Labeled Red Blood Cells
The purpose of this research is to evaluate the impact of genetic and biologic factors in blood donors on red blood cell storage stability after autologous transfusion over the different range of storage period of 5-7 days and…
- Trial name
- NCT03364686
- Testing
- Biotin-Labeled Red Blood Cells
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Gladwin, Mark, MD
Elderly, Solid Malignancy
Geriatric Oncology Surgical Assessment and Functional rEcovery After Surgery
Multicenter, international, prospective, observational study, designed to evaluate the postoperative results in terms of quality of life and functional recovery of elderly patients after major cancer surgery.
- Trial name
- GOSAFE (NCT03299270)
- Testing
- Questionnaires
- Where
- 28 sites in United States, Greece and 8 more
- Volunteers
- 1,004 people
- Sponsor
- AUSL ROMAGNA
Mental Illness, Chronic Disease
Comparative Effectiveness of IIMR Versus CDSMP
The study will enroll 600 people with serious mental illness who receive services at Centerstone in KY or TN and will compare two different evidence-based self-management interventions: Integrated Illness Management and Recovery…
- Trial name
- NCT03966872
- Testing
- Integrated Illness Management and Recovery, Chronic Disease Self-Management Program
- Where
- 2 sites in United States
- Volunteers
- 601 people
- Sponsor
- Dartmouth-Hitchcock Medical Center
SARS-CoV Infection
Recovery of Exertion Ability Following COVID-19 Infection in Military Staff
The Paris Fire Brigade staff have been particularly exposed to COVID-19 due to rescue and care activities for victims at risk in Paris area (where the virus was actively circulating).
- Trial name
- CovEx (NCT04548505)
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Direction Centrale du Service de Santé des Armées
Stroke, Cardiovascular
Effects of Thermal Stimulation on Motor Recovery and Neuromuscular Property of Lower Extremity in Stroke
This 3-year study will recruit a total of 72 subjects with first-ever stroke after 3 months onset from the department of Physical Medicine and Rehabilitation in 3 teaching hospitals.
- Trial name
- NCT04306120
- Testing
- Traditional Rehabilitation Therapy
- Where
- Taiwan
- Volunteers
- 37 people
- Sponsor
- Kaohsiung Medical University Chung-Ho Memorial Hospital
Physical Therapy
Impact of Physiotherapy Intervention for Children With Ankle Sprains
This study will investigate whether adding a physiotherapy intervention to standard Emergency Department care will lead to improved recovery following an ankle sprain in the pediatric and adolescent population as well as to a…
- Trial name
- NCT01405274
- Testing
- Physiotherapy
- Where
- Canada
- Volunteers
- 170 people
- Sponsor
- McGill University Health Centre/Research Institute of the McGill University Health Centre
Critical Illness, Mechanical Ventilation
Analysis of Weaning of Analgosedation and Kinetics of Emergence in Critically Ill Patients
The goal of this prospective multicenter observational study is to characterize early trajectories of consciousness recovery following the first valid structured awakening trial in mechanically ventilated critically ill adults, a…
- Conditions
- Critical Illness, Mechanical Ventilation, Weaning Invasive Mechanical Ventilation, Sedation and Analgesia
- Trial name
- AWAKE-ICU (NCT07710066)
- Testing
- Structured Awakening Evaluation (SAE)
- Volunteers
- 500 people
- Sponsor
- Patricia Rodriguez Villamizar
Postoperative Period, Lung Cancer (Diagnosis)
Investigation of the Effects of Tele-Yoga Training in Individuals With Lung Cancer Undergoing Lung Resection Surgery
This randomized controlled clinical trial aims to evaluate the effects of an 8-week tele-yoga intervention in individuals with lung cancer who have undergone lung resection surgery.
- Trial name
- NCT07001670
- Testing
- Tele-Yoga Training
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Istanbul University
Acute Appendicitis, Acute Appendicitis With Rupture
Modified Enhanced Recovery Program in Emergency Surgery (MERES)
Laparoscopic appendectomy (LA) is a widespread surgical procedure. Patients may develop considerable postoperative pain and dyspepsia resulting in prolong in-hospital stay.
- Conditions
- Acute Appendicitis, Acute Appendicitis With Rupture, Acute Appendicitis With Peritonitis, Acute Appendicitis Without Peritonitis
- Trial name
- MERES (NCT03754777)
- Testing
- Laparoscopic appendectomy
- Where
- Russia
- Volunteers
- 122 people
- Sponsor
- Pirogov Russian National Research Medical University
Lumbar Spinal Stenosis
Assessment of Gait Parameters and Their Impact on Postoperative Recovery in Patients With Lumbar Spinal Stenosis
The objective is to observe the evolution of walking parameters during the surgery process and find which of all calculated walking parameters represent the best indicators of functional disabilities and postoperative recovery…
- Trial name
- NCT04250753
- Testing
- Walking task
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Université du Québec à Trois-Rivières
Parkinson Disease
Mass Balance Recovery and Metabolite Identification of Carbon-14 BIA 28-6156
The study is designed to determine the absorption, distribution, metabolism and elimination (ADME) of BIA 28-6156 in humans, further explore the PK of BIA 28-6156, evaluate the extent of distribution of total radioactivity into…
- Trial name
- NCT05220072
- Testing
- Carbon-14 BIA 28-6156
- Where
- United Kingdom
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Bial R&D Investments, S.A.