Clinical trials: Astigmatism
Nearsightedness, Astigmatism
High Resolution Wavefront-guided vs. Wavefront Optimized LASIK
The investigators are comparing outcomes of LASIK surgery using a high definition wavefront-guided laser to a wavefront-optimized laser in patients with nearsightedness with and without astigmatism.
- Trial name
- NCT02565537
- Testing
- LASIK
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Stanford University
Refractive Errors, Myopia
Correlation Between Preoperative Refraction and Anterior Segment Parameters With ICL Vault
This prospective non-comparative interventional study aims to analyse the pre-operative factors affecting the range of optimal ICL vaulting.
- Conditions
- Refractive Errors, Myopia, Myopic Astigmatism
- Trial name
- NCT05670626
- Testing
- Refractive Surgery
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Kasr El Aini Hospital
Astigmatism
Performance Evaluation of Two Silicone Hydrogel Toric Lens Designs in Habitual Soft Contact Lens Wearers
The objective of the study was to compare the clinical performance of two monthly toric silicone hydrogel contact lenses in habitual wearers, when worn for 1-month each.
- Trial name
- NCT05933772
- Testing
- Lens A (comfilcon A toric lens), Lens B (lehfilcon A toric lens)
- Where
- 5 sites in United States, Canada
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- CooperVision International Limited (CVIL)
Contact Lens Complication, Astigmatism
Total30 for Astigmatism Contact Lenses
Determine if Total30 for Astigmatism contact lenses (CLs) provide a comfortable wearing experience all day. CL discomfort affects most CL wearers with discomfort consistently topping the reasons why established CL wearers drop…
- Conditions
- Contact Lens Complication, Astigmatism, Refractive Errors
- Trial name
- NCT06052046
- Testing
- TOTAL30 for Astigmatism Contact Lenses
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Contact Lens Complication, Astigmatism
T30 for Astigmatism in Digital Device Users
This study aims to determine if Total30 lenses for astigmatism can be successfully fit in participants who are heavy digital device users.
- Conditions
- Contact Lens Complication, Astigmatism, Refractive Errors
- Trial name
- T30FA (NCT06266728)
- Testing
- Total30 for Astigmatism Contact Lenses
- Where
- 2 sites in United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Astigmatism
Safety and Effectiveness of Wavefront-guided LASIK for the Correction of Mixed Astigmatism
To demonstrate that wavefront-guided LASIK with measurements from iDesign is safe and effective in the treatment of mixed astigmatism.
- Trial name
- NCT01675492
- Testing
- LASIK
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Cataract, Astigmatism
Post-Approval Study of the TECNIS® Toric Extended Cylinder Range Intraocular Lens (IOL)
This study is a prospective, multicenter, bilateral, non-randomized, open-label, clinical study conducted at up to 20 sites in the USA.
- Trial name
- NCT02649842
- Testing
- TECNIS Toric Models ZCT450, ZCT525 or ZCT600
- Volunteers
- 101 people, healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Myopia, Hyperopia
Complete Easy Rub Comparative Efficacy Study
The aim of this trial is to assess Complete Easy Rub compared to a competitor multi-purpose solution in terms of lens cleanliness, subjective response and ocular response, when lenses are worn bilaterally on a daily wear basis…
- Conditions
- Myopia, Hyperopia, Astigmatism
- Trial name
- NCT01019564
- Testing
- Complete Easy Rub Formula MPS, Aquify MPS
- Volunteers
- healthy volunteers welcome
- Sponsor
- Abbott Medical Optics
Astigmatism Bilateral, Eyeglasses
Spectacle Prescribing in Early Childhood
The purpose of this study is to compare developmental outcome for young children (12 to 35 months of age) with astigmatism meeting American Academy of Ophthalmology spectacle prescribing guidelines and who are prescribed and…
- Trial name
- SPEC (NCT04728451)
- Testing
- Spectacle wear support, Spectacles
- Where
- United States
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- University of Arizona
Cataract, Presbyopia
Clinical Investigation of a Small Aperture Extended Depth of Focus Intraocular Lens in Patients With Complex Corneas
The objective of this study is to evaluate the clinical outcomes of the IC-8 IOL implanted in patients with complex corneas after crystalline lens removal.
- Conditions
- Cataract, Presbyopia, Irregular Astigmatism
- Trial name
- NCT05574270
- Testing
- IC-8 Intraocular Lens (IOL)
- Where
- 2 sites in Philippines, Singapore
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- AcuFocus, Inc.
Astigmatism
Kalifilcon A Toric Compared to Commercially Available Lenses
Approximately thirty contact lens adapted subjects will be enrolled in this feasibility, bilateral, randomized, double masked (subject and investigator masked), repeated measures insertion study.
- Trial name
- NCT06098937
- Testing
- Kalifilcon Toric Lens, Total1 for Astigmatism, Precision1 for Astigmatism
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Bausch & Lomb Incorporated
Astigmatism
Application of Phototherapeutic Keratectomy Mode to Mark the Axis of Astigmatism
Corneal refractive surgery is an effective way to correct refractive error. Modern corneal refractive surgery for the correction of myopia or hyperopia can achieve or close to the expected goal, but to eliminate astigmatism is…
- Trial name
- NCT06694051
- Testing
- marking
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital
Nearsightedness, Farsightedness
An Evaluation of LASIK, SMILE and PRK Surgery in Physicians
The principle investigator is evaluating self-reported quality of vision and quality of life in physicians undergoing LASIK, SMILE and PRK surgery.
- Conditions
- Nearsightedness, Farsightedness, Astigmatism
- Trial name
- NCT02576483
- Testing
- Questionnaire (QoV questionnaire)
- Where
- United States
- Volunteers
- 700 people, healthy volunteers welcome
- Sponsor
- Stanford University
Visual Acuity, Astigmatism
LFR-260 vs Traditional Phoropter in Visual Acuity Testing
The purpose of this study is to establish if LFR-260 (investigational device) is not inferior in effectiveness to a traditional phoropter (control device) when applied in visual acuity test in subjects undergoing a full routine…
- Conditions
- Visual Acuity, Astigmatism, Anisometropia
- Trial name
- NCT05259163
- Testing
- LFR-260 portable phoropter, Traditional phoropter (SOC)
- Where
- 2 sites in United States
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Evolution Optiks Limited
Myopia, Astigmatism
Contralateral Study of Topography Guided LASIK Versus Small Incision Lenticule Extraction
This study evaluates differences in postoperative visual outcomes between patients receiving Topography-Guided LASIK in one eye and Small Incision Lenticule Extraction in the other eye.
- Trial name
- NCT05611294
- Testing
- Topography Guided LASIK Surgery, Small Incision Lenticule Extraction Surgery
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hoopes Vision
Keratoconus, Irregular Astigmatism
Wavefront Guided Scleral Lenses for Keratoconus and Irregular Astigmatism
Aberrations are the spreading of light from a point focus. Aberrations of the eyes can be objectively evaluated with a wavefront aberrometer.
- Conditions
- Keratoconus, Irregular Astigmatism, Corneal Ectasia, Aberration, Corneal Wavefront
- Trial name
- WFG Sclerals (NCT04698590)
- Testing
- Wavefront Guided Scleral Lenses, Traditional Scleral Lenses
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Cornea and Laser Eye Institute
Astigmatism Bilateral
Evaluation of Wear Experience With Daily Disposable and Monthly Replacement Toric Contact Lenses
Comparison of wear experience with daily disposable and monthly replacement soft contact lenses in contact lens wearers who have astigmatism.
- Trial name
- NCT05580575
- Testing
- Daily disposable toric soft contact lens, Monthly replacement toric daily wear soft contact lens
- Where
- 3 sites in United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia, Astigmatism
Quality of Vision and Quality of Life With LASIK
The investigators are administering a validated questionnaire looking at patient reported quality of life and quality of vision after LASIK surgery
- Conditions
- Myopia, Astigmatism, Quality of Lifte
- Trial name
- NCT02161263
- Testing
- Patient Quality of Life andVision after LASIK Surgery
- Where
- United States
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Edward E. Manche
Astigmatism
Limbal Astigmatic Keratotomy to Correct High Degrees of Astigmatism After Phacoemulsification
Compare manually performed Astigmatic Keratotomy to femtosecond laser astigmatic keratotomy to manage corneal astigmatism more than three diopters after phacoemulsification.
- Trial name
- NCT06179355
- Testing
- manual astigmatic keratotomy, femtosecond laser astigmatic keratotomy
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Ocular Surface Disease, Irregular Astigmatism
Evaluation of the Safety and Efficacy of Rigid Breathable Scleral Contact Lenses for the Correction of Ametropia
To evaluate the short-term efficacy and safety of scleral contact lens in the clinical treatment of patients with irregular astigmatism after corneal transplantation by analyzing ocular parameters and ocular surface conditions of…
- Conditions
- Ocular Surface Disease, Irregular Astigmatism, Contact Lens Complication, Corneal Astigmatism
- Trial name
- NCT06256770
- Where
- China
- Volunteers
- 176 people, healthy volunteers welcome
- Sponsor
- Tianjin Eye Hospital