Clinical trials: Astigmatism, active
Refractive Assessment, Refractive Disorders
Algorithm-assisted Subjective Refraction Program Dedicated to Children
Current refraction assessment in children is dependent on the Eye Care Specialist and lacks standardization. Essilor has developed new algorithm assisted subjective refraction software dedicated to children of 6-12 years old and…
- Conditions
- Refractive Assessment, Refractive Disorders, Hyperopia and Myopia, Astigmatism
- Trial name
- NCT07046065
- Testing
- Non-cycloplegic Objective refraction, Non-cycloplegic conventional subjective refraction, Non-cycloplegic subjective refraction (Kids refraction software vA with Vision-R™)
- Where
- Portugal
- Volunteers
- 166 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia, Myopic Astigmatism
A Clinical Trial Assessing the Safety and Effectiveness of Orthokeratology Lenses in Patients With Myopia and Myopic Astigmatism
This is a prospective, multi-centre, single-arm clinical trial to evaluate the effectiveness and safety of MCOK-01 lenses in patients with myopia and myopic astigmatism who need dioptric correction.
- Trial name
- SEMOA (NCT07047924)
- Testing
- MCOK-01
- Where
- 4 sites in Australia
- Volunteers
- 220 people
- Sponsor
- Menicon Co., Ltd.
Myopia
Development of a New Device and Method to Assess the Degree of Myopia and/or Astigmatism in Myopic People
The purpose of this clinical investigation is to check whether the new device can correctly measure a person's degree of myopia and astigmatism.
- Trial name
- MDSW_DiVA2Rx (NCT07297810)
- Testing
- Optical correction values obtained with investigational device and visual acuity, Optical correction values obtained with an autorefractometer and visual acuity, Optical correction values obtained with a phoropter and visual acuity
- Where
- France
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Essilor International
Myopia, Astigmatism
SMILE Surgery in One Eye Compared to Ray Tracing-guided LASIK Surgery in the Fellow Eye
Participants will undergo LASIK surgery in one eye using ray tracing guided technology in one eye and LASIK surgery in the other eye using wavefront guided technology.
- Trial name
- NCT07721714
- Testing
- Ray tracing guided LASIK surgery
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Stanford University
Visual Acuity, Refractive Errors
Assessing the Turkish DDIVAT for Visual Acuity Measurement
The goal of this observational methodological study is to validate the Turkish version of the DDIVAT visual acuity measuring device in a Turkish-speaking adult population.
- Conditions
- Visual Acuity, Refractive Errors, Myopia, Hyperopia
- Trial name
- NCT07240480
- Testing
- DDIVAT Visual Acuity Test (Turkish Version)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Trakya University
Age Related Cataracts, Astigmatism
Rotation of Hydrophobic Acrylic Lenses - Rayner RA0800C & Alcon Clareon & Hoya Nanex & Hoya Vivinex XY1-EM & RayOne EMV Toric & PODEYE Toric
The investigational devices are approved intraocular lenses (IOL) intended to be implanted after phacoemulsification in individuals suffering from age-related cataract with the need of cataract surgery.
- Trial name
- NCT03803852
- Testing
- Intraocular Lens Implantation
- Where
- Austria
- Volunteers
- 750 people
- Sponsor
- Medical University of Vienna
Astigmatism
Clinical Performance and Outcomes After Toric Lens Transition
To evaluate subjective and clinical outcomes after transitioning from one toric soft contact lens to another over a one-month period.
- Trial name
- NCT07898995
- Testing
- Fanfilcon A Toric Contact Lens
- Where
- United States
- Volunteers
- 35 people
- Sponsor
- CooperVision International Limited (CVIL)
Hyperopia, High Astigmatism
Fresh Corneal Lenticule Implantation in Hyperopic Patients With High Astigmatism
The refractive combination of high hyperopia with high astigmatism is difficult to treat surgically. In addition, there are not many suitable options to offer such patients presenting with this condition.
- Trial name
- NCT04616144
- Testing
- Fresh Corneal Lenticule Implantation using Relex-Smile VisuMax Femtosecond Laser
- Where
- Kosovo
- Volunteers
- 55 people
- Sponsor
- Eye Hospital Pristina Kosovo
Keratoconus, Keratoconus, Artificial Intelligence, Support Vector Machine
Predicting Manifest Astigmatism in Keratoconus Patients.
The cornea of the human eye has several functions. It is transparent to allow light into the eye and its shape focuses the incoming light onto the retina.
- Trial name
- NCT06798779
- Testing
- Glasses, Corneal topography
- Where
- United Kingdom
- Volunteers
- 800 people
- Sponsor
- Royal Devon and Exeter NHS Foundation Trust
Myopia, Hyperopia
Corneal Epithelial Thickness Mapping by Anterior Segment Optical Coherence Tomography in Patients With Refractive Errors
This study evaluates corneal epithelial thickness using anterior segment optical coherence tomography (AS-OCT) in patients with refractive errors.
- Conditions
- Myopia, Hyperopia, Astigmatism, Emmetropia
- Trial name
- NCT07647146
- Where
- Egypt
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Sohag University
Myopia, Astigmatism
Wavelight Plus Sightmap-LASIK vs. Wavefront-Optimized-LASIK
The goal of this clinical trial is to learn if the wavelight plus Sightmap (WLP) method or the wavefront-optimized (WFO) method for calculating LASIK customization treatment gives better vision, better satisfaction, and fewer…
- Trial name
- NCT07855094
- Testing
- LASIK calculated ablation using Wavefront-Optimized, wavelight plus Sightmap (WLP) Guided LASIK calculated
- Where
- United States
- Volunteers
- 49 people
- Sponsor
- 59th Medical Wing
Keratoconus, High Myopia
Anterior Segment and Corneal Parameters in Keratoconus and High Myopic Astigmatism Using Schiempflug Imaging
The purpose of this study was to compare Scheimpflug corneal tomography findings in keratoconus and high myopic astigmatic eyes, as well as to establish the parameters distinguishing keratoconus from high myopic astigmatism.
- Trial name
- NCT06739018
- Testing
- pentacam scheimpflug tomography
- Where
- 2 sites in Egypt
- Volunteers
- 66 people
- Sponsor
- Assiut University
Myopia, Astigmatism
Study of a Phakic Implantable Collamer Lens (ICL)
A prospective, open-labeled, single-site study of a phakic implantable collamer lens (ICL) for the correction/reduction of myopia with or without astigmatism.
- Trial name
- NCT07790965
- Testing
- Phakic Implantable Collamer Lens (ICL)
- Volunteers
- 10 people
- Sponsor
- Staar Surgical Company
Irregular Astigmatism
Intrastromal Fresh Human Corneal Lenticule Implantation Using Smile Surgery for Treatment of Irregular Corneal Astigmatism After Penetrating Keratoplasty (New Approach)
The aim of the study is to present the effect of implanting intrastromal fresh corneal lenticule by SMILE surgery as a new method-approach to correct the corneal shape on purpose to reduce irregular astigmatism and increasing…
- Trial name
- NCT04987060
- Testing
- Intrastromal Fresh Human Lenticule Implantation
- Where
- Kosovo
- Volunteers
- 24 people
- Sponsor
- Eye Hospital Pristina Kosovo
Myopia, Astigmatism
A Three-Phase Contralateral Comparison of Ray-Tracing Guided LASIK Versus Three Other Refractive Surgery Platforms to Correct Myopia or Myopia With Astigmatism
This purpose of this study is to compare a new form of LASIK called Ray Tracing Guided LASIK to 3 other forms of corneal refractive surgery: 1. KLEx (KeratoLenticule Extraction) using the Zeiss Visumax 800 Laser, 2.
- Trial name
- NCT07201298
- Testing
- Ray-Tracing Guided LASIK, Keratorefractive Lenticule Extraction (KLEx), WaveFront Optimized LASIK
- Where
- United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Hoopes Vision
Contact Lens Comfort
Acuvue Oaysis Contact Lens Wearers Being Refit Into P7 Contact Lenses
Determine the likelihood of successfully refitting a satisfied AOA CL wearers into P7A CLs
- Trial name
- NCT06955403
- Testing
- Precision 7 contact lenses
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Southern College of Optometry
Astigmatism
Observational Study - TA- 2025-1
This multi-centric, prospective observational study collects biometric datasets as well as associated video recordings of the surgical procedure.
- Trial name
- TA OS 2025-1 (NCT07007897)
- Testing
- Optical Biometry, Cataract Surgery
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Haag-Streit AG
Astigmatism
Wear Experience With Daily Disposable Contact Lenses for Astigmatism Over a Long-Wear Day
The purpose of this study to assess the wear experience of people who have astigmatism when wearing a daily disposable contact lens for astigmatism over long days of wear.
- Trial name
- NCT07303920
- Testing
- Daily disposable contact lenses for astigmatism
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Ohio State University
Myopia, Astigmatism
Clinical Evaluation of WaveLight Plus LASIK
This study is a single-site, single-arm, prospective, observational study of subject satisfaction, quality of vision, and quality of life after bilateral LASIK surgery. Subjects will be assessed up to 3 months post-operatively.
- Trial name
- NCT07127757
- Testing
- Wavelight Plus LASIK
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Laser Defined Vision
Myopia, Astigmatism
KLEx Versus FS-LASIK for the Treatment of Myopia and Compound Myopic Astigmatism
FemtoLASIK is a type of laser eye surgery used to correct vision problems such as nearsightedness, farsightedness, and astigmatism. It involves two main steps: creating a flap and reshaping the cornea.
- Conditions
- Myopia, Astigmatism, Myopic Astigmatism
- Trial name
- NCT06477081
- Testing
- FS-LASIK procedure, KLEx
- Where
- Mexico
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Instituto de Oftalmología Fundación Conde de Valenciana