Clinical trials: Atrial Fibrillation Catheter Ablation
Atrial Fibrillation
PVAC GOLD Versus Irrigated RF Single Tip Catheter With Contact FORCE Ablation of the Pulmonary Veins for Treatment of Drug Refractory Symptomatic Paroxysmal and Persistent Atrial Fibrillation
The GOLD FORCE trial investigates the differences between treatment with a Contact Force single-tip catheter against the PVAC GOLD multielectrode catheter in cardiac ablation procedures in patients with paroxysmal atrial…
- Trial name
- GOLD-FORCE (NCT02463851)
- Testing
- PVAC GOLD multielectrode catheter, Contact Force single-tip ablation catheter
- Where
- 3 sites in Germany, Netherlands
- Volunteers
- 212 people
- Sponsor
- L.V.A. Boersma
Atrial Fibrillation
Role of Subsequent Atrial Tachycardia in Mechanisms of Persistent AF
In this study, the investigators aim to examine the prognostic role of subsequent Atrial Tachycardias (ATs) in the mechanisms of atrial fibrillation (AF).
- Trial name
- NCT01896570
- Testing
- Catheter ablation of subsequent atrial tachycardia
- Where
- Germany
- Volunteers
- 110 people
- Sponsor
- Johannes Gutenberg University Mainz
Persistent Atrial Fibrillation
One Staged Hybrid Approach of Surgical/Catheter Ablation for Persistent Atrial Fibrillation
There are 10 million atrial fibrillation (AF) patients in China, and the patients are risk of stroke, heart failure and sudden death.
- Trial name
- NCT02968056
- Testing
- Radiofrequency ablation
- Where
- China
- Volunteers
- 160 people
- Sponsor
- Xinhua Hospital, Shanghai Jiao Tong University School of Medicine
Atrial Fibrillation
Giant Left Atrium Atrial fibrillatioN CathEter Ablation, Posterior Box Isolation vs. Dallas Lesion Set
Although the additional linear ablation after pulmonary vein isolation (PVI) is a class IIB indication for AF catheter ablation in patients with persistent AF, no clear benefit has been demonstrated in the recent randomized…
- Trial name
- NCT04632550
- Testing
- Circumferential pulmonary vein isolation(CPVI) group, Posterior box isolation(POBI) group, POBI+Anterior linear ablation(AL) group
- Where
- South Korea
- Volunteers
- 480 people
- Sponsor
- Yonsei University
Atrial Fibrillation
Efficacy and Safety Study of Catheter Ablation for Atrial Fibrillation
To compare the efficacy of different procedures, identify the optimal procedure, ablation sites, ablation endpoints and post-operative anticoagulation strategy, establish the optimal treatment strategy for atrial fibrillation.
- Trial name
- NCT01113294
- Testing
- catheter ablation
- Where
- China
- Volunteers
- 2,040 people
- Sponsor
- Wuhan University
Atrial Fibrillation
Prophylactic Pulmonary Vein Isolation Study
This study is being done to learn the effects of the Pulmonary Vein Isolation in patients that are at high risk to developing, but do not have a documented history of atrial fibrillation.
- Trial name
- NCT00587899
- Testing
- Pulmonary Vein Isolation
- Where
- United States
- Volunteers
- 41 people
- Sponsor
- Mayo Clinic
Atrial Fibrillation
INtra-procedural ultraSound Imaging During Pulmonary Veins Isolation
One of the biggest limitations of the currently used percutaneous techniques for Pulmonary Vein Isolation (PVI) in the setting of atrial fibrillation ablation is the lack of real-time information about the left atrial (LA) wall…
- Trial name
- INSIDEPVs (NCT03372798)
- Testing
- ICE/IVUS imaging during atrial fibrillation ablation
- Where
- United Kingdom
- Volunteers
- 14 people
- Sponsor
- Oxford University Hospitals NHS Trust
Atrial Fibrillation
Ten-year Outcomes After AF Ablation
Ablation of atrial fibrillation (AF) using pulmonary vein isolation is employed when patients do not respond favorably to medical therapy.
- Trial name
- NCT01867099
- Where
- United States
- Volunteers
- 445 people
- Sponsor
- Valley Health System
Paroxysmal Atrial Fibrillation
Efficacy of Pilsicainide After Radiofrequency Ablation of Paroxysmal Atrial Fibrillation
Investigators hypothesized that the use of Pilsicainide after radiofrequency ablation of AF could reduce the incidence of recurrence of atrial arrhythmia during follow up compared with other class IC antiarrhythmic drugs.
- Trial name
- NCT01775891
- Testing
- pilsicainide, other class IC antiarrhythmic drug
- Where
- South Korea
- Volunteers
- 245 people
- Sponsor
- Korea University
Atrial Fibrillation
Effect of Amiodarone on the Procedure Outcome in Long-standing Persistent Atrial Fibrillation Undergoing Pulmonary Vein Antral Isolation
This prospective randomized study aims to investigate the effect of continuous versus interrupted use of Amiodarone on the procedure outcome in long-standing persistent (LSP) atrial fibrillation patients undergoing pulmonary vein…
- Trial name
- SPECULATE (NCT01173809)
- Testing
- Amiodarone
- Where
- United States
- Volunteers
- 176 people
- Sponsor
- Texas Cardiac Arrhythmia Research Foundation
Atrial Fibrillation
Effect of Balloon Cryoablation on Left Atrial Function
Atrial fibrillation is a common and disabling irregular heart rhythm, that affects 1 to 1.5 million Americans. Recent clinical experience with the Medtronic Arctic Front™ Cardiac CryoAblation Catheter System suggests that it can…
- Trial name
- CRYO-LA (NCT00821015)
- Testing
- Pulmonary vein isolation with cryoballoon catheter
- Volunteers
- 27 people
- Sponsor
- Vivek Reddy
Patients With Atrial Fibrillation Undergoing Catheter Ablation
Comparison of Patients' Satisfaction Between Dexmedetomidine and Remimazolam Anesthesia in Patients With Atrial Fibrillation Undergoing Catheter Ablation
The primary purpose of this study was to investigate whether remimazolam administration for sedation had a positive effect on patients' satisfaction compared to dexmedetomidine administration in patients with atrial fibrillation…
- Trial name
- NCT05864404
- Testing
- remimazolam-remifentanil, dexmedetomidine-remifentanil
- Where
- South Korea
- Volunteers
- 142 people
- Sponsor
- Yonsei University
Atrial Fibrillation, Ischemic Ventricular Tachycardia
Study of a New Catheter Using Force Sensing Capabilities for the Treatment of Atrial Fibrillation and Ventricular Tachycardia
The purpose of this study is to study the treatment of Atrial Fibrillation and ischemic Ventricular Tachycardia using a RF ablation catheter with contact force sensing capabilities.
- Trial name
- EZCF-125 (NCT01032317)
- Testing
- Radiofrequency Catheter Ablation
- Where
- Czechia
- Volunteers
- 22 people
- Sponsor
- Biosense Webster, Inc.
Cardiac Arrhythmias, Atrial Fibrillation
Improved Procedural Workflow For Catheter Ablation Of Paroxysmal AF With High Density Mapping System And Advanced Technology
DELETE AF is a prospective, multicenter, non-randomized post-market study. All patients will be treated according to the standard care followed by each center.
- Trial name
- DELETE AF (NCT05005143)
- Volunteers
- 200 people
- Sponsor
- Clinica Universidad de Navarra, Universidad de Navarra
Atrial Fibrillation
Catheter Contact Force and Electrograms
Until recently, there was no way of telling how firmly the tip of the catheter was in contact with the heart and how this contact was orientated.
- Trial name
- NCT01587404
- Testing
- THERMOCOOL® SMARTTOUCH™ Catheter (including Surround Flow)
- Where
- United Kingdom
- Volunteers
- 55 people
- Sponsor
- Barts & The London NHS Trust
Atrial Fibrillation
Atrial Fibrillation Ablation: Radiofrequency or Cryoablation?
The study aims to compare 3 techniques routinely used for paroxysmal atrial fibrillation ablation: radiofrequency catheter ablation without contact-force, radiofrequency catheter ablation with contact-force and cryoablation.
- Trial name
- ARCFA (NCT03774550)
- Where
- France
- Volunteers
- 206 people
- Sponsor
- Centre Hospitalier Régional Metz-Thionville
Atrial Fibrillation, Arrhythmia
First-time Ablation of Atrial Fibrillation Registry
Atrial fibrillation (AF) is a prevalent cardiac arrhythmia affecting millions globally, with projections indicating a doubling of cases by 2050.
- Trial name
- DIPE (NCT06381245)
- Testing
- PPG-based remote heart rhythm/rate monitoring, ECG-based remote heart rhythm/rate monitoring, Transthoracic and transesophageal echocardiography examination
- Where
- Poland
- Volunteers
- 340 people
- Sponsor
- Medical University of Warsaw
Atrial Fibrillation
Radiofrequency Catheter Ablation for Chronic Atrial Fibrillation
The purpose of this study is to determine the long-term efficacy of radiofrequency catheter ablation in patients with chronic atrial fibrillation.
- Trial name
- NCT00272636
- Testing
- Radiofrequency catheter ablation, Amiodarone and cardioversion
- Where
- 2 sites in United States, Italy
- Volunteers
- 140 people
- Sponsor
- University of Michigan
Atrial Fibrillation
Half-normal Saline in Atrial Fibrillation Ablation
The study evaluates the use of half-normal saline as an irrigant for open-irrigated catheters during atrial fibrillation ablation.
- Trial name
- NCT03498586
- Testing
- Half-normal saline, Normal saline
- Where
- 2 sites in United States, Canada
- Volunteers
- 99 people
- Sponsor
- Texas Cardiac Arrhythmia Research Foundation
Atrial Fibrillation (AF), Catheter Ablation
Efficacy and Safety of Catheter abLation in patiEnts With seVere mitrAl regurgiTation and pErsistent Atrial Fibrillation: a Randomized Controlled Trial
Atrial fibrillation (AF) leads to atrial functional mitral regurgitation (MR) through mechanisms including mitral annular dilatation, systolic leaflet motion distance alteration, and contractility decrease.
- Conditions
- Atrial Fibrillation (AF), Catheter Ablation, Atrial Functional Mitral Regurgitation
- Trial name
- ELEVATE-AF (NCT06883864)
- Testing
- Catheter ablation plus medication, Medication, (ELEVATE-AF X) experimental group
- Where
- 17 sites in China
- Volunteers
- 146 people
- Sponsor
- Beijing Anzhen Hospital