Clinical trials: Atrial Fibrillation Recurrent
Atrial Fibrillation
Posterior Wall And Left Atrial Appendage Empiric Electrical Isolation for Non-Paroxysmal Atrial Fibrillation
The purpose of this study is to evaluate the safety and effectiveness of empirical posterior wall isolation (PWI), left atrial appendage electrical isolation (LAAEI) and coronary sinus isolation (CSI) when compared to pulmonary…
- Trial name
- PLEA (NCT04216667)
- Testing
- Catheter ablation
- Where
- 16 sites in United States, Argentina and 5 more
- Volunteers
- 124 people
- Sponsor
- Montefiore Medical Center
Recurrent Atrial Fibrillation, Persistent Atrial Fibrillation
AV Junction Ablation or Optimal Medical Treatment in PatiEnts With Cardiac Resynchronization Therapy and Permanent Atrial Fibrillation
A study comparing atrioventricular junction ablation (AVJA) versus continued optimum medical rate control in patients with cardiac resynchronization therapy (CRT) and atrial fibrillation (AF) with suboptimal heart rate control on…
- Trial name
- AMPER-AF (NCT05776797)
- Testing
- Atrioventricular junction ablation in patients with cardiac resynchronization therapy (CRT), Optimal medication treatment in patients with cardiac resynchronization therapy (CRT)
- Where
- 9 sites in Czechia
- Volunteers
- 480 people
- Sponsor
- University Hospital Ostrava
Paroxysmal Atrial Fibrillation, Hypertension
Renal Denervation and pUlmonary Vein isolAtion With cryoabLation on Patients With Atrial Fibrillation and hypErtension
The DUAL-ICE study is a single-center, prospective, randomized controlled study. The main purpose is to verify that renal artery cryoablation combined with pulmonary vein cryoablation can reduce the recurrence of atrial…
- Trial name
- NCT05024630
- Testing
- Renal artery cryoablation, Pulmonary vein cryoablation, Renal arteriography
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Shanghai 10th People's Hospital
Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation
High-Density (HD) Wave Mapping in Subjects With Atrial Fibrillation as a Predictor of Recurrence After a Single Ablation Procedure Using a PVI-Only Strategy
The aim is to use the Advisor™ HD Grid Mapping Catheter, Sensor Enabled™ to characterize the atrial substrate and develop a model for predicting recurrence rates after a single procedure using a PVI only approach and a contact…
- Conditions
- Paroxysmal Atrial Fibrillation, Persistent Atrial Fibrillation, Cardiac Arrhythmia
- Trial name
- WAVE-MAP AF (NCT03882021)
- Testing
- A specific electrophysiology mapping protocol is applicable with the GRID catheter.
- Where
- 15 sites in Austria, Czechia and 7 more
- Volunteers
- 300 people
- Sponsor
- Abbott Medical Devices
Persisent Atrial Fibrillation, Reversal of Atrial Enlargement
Left Atrial Volume Changes Who Underwent Cardioversion and Recurrence of AF After RF Ablation in Persistent AF (SAFE-AF)
Electrical/pharmacological cardioversion improves structural remodeling of left atrium. We hypothesize that persistent atrial fibrillation (AF) patients with more significant left atrial size reduction after cardioversion have…
- Conditions
- Persisent Atrial Fibrillation, Reversal of Atrial Enlargement, Recurrence of Atrial Fibrillation
- Trial name
- SAFE-AF-ABL (NCT06523738)
- Testing
- 1. electrical/pharmacological cardioversion. 2.pulmonary vein isolation
- Where
- China
- Volunteers
- 100 people
- Sponsor
- The Second Affiliated Hospital of Chongqing Medical University
Atrial Fibrillation
Role of Eplerenone in Reducing Recurrence of Atrial Fibrillation in Patients With Structural Heart Disease
This is a prospective comparative study, conducted at Cardiology Department, Aswan University Hospital on AF patients with structural heart disease.
- Trial name
- NCT06556732
- Testing
- Eplereone
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Atrial Fibrillation, Atrial Flutter
Therapy of Atrial Flutter by Afib Ablation
Ablation of the cavotricuspid isthmus (CTI) in the right atrium is currently the therapy of choice for the treatment of typical atrial flutter (3,4). It is a curative approach and has a high success rate (5).
- Trial name
- TripleA (NCT02051621)
- Testing
- Antiarrhythmic drug, Cavo-tricuspid-isthmus-ablation, Pulmonary vein isolation
- Where
- Germany
- Volunteers
- 100 people
- Sponsor
- University of Rostock
Atrial Fibrillation (AF)
Evaluation of Probiotics' Effect on Atrial Fibrillation Recurrence in Patients Undergoing Cardioversion
The aim of this clinical study is to evaluate the efficacy and tolerability of probiotics on atrial fibrillation recurrence.
- Trial name
- NCT07568964
- Testing
- Anticoagulant Therapy, Probiotics capsules
- Where
- Egypt
- Volunteers
- 56 people
- Sponsor
- Ain Shams University
Atrial Fibrillation
Hidden Slow Conduction Ablation for Recurrent Atrial Fibrillation: Unmasking the Arrhythmogenic Substrate (Unmask-AF)
Over recent years, pulmonary vein isolation (PVI) procedures have demonstrated progressively enhanced efficacy and safety, resulting in a substantial increase in the number of atrial fibrillation ablations, not only as a…
- Trial name
- NCT06657170
- Testing
- Pulmunary veins reconnection plus hidden slow conduction ablation, Pulmunary veins (PV) reconnection ablation only
- Volunteers
- 212 people
- Sponsor
- Centro Medico Teknon
Stroke
Left Atrial Function in Recurrent Stroke of Unknown Cause
Stroke is an important cause of disability and the third leading cause of death. Approximately 30 to 40 % of all strokes are estimated to be cryptogenic (i.e. no cause can be found).
- Trial name
- NCT02968329
- Where
- Belgium
- Volunteers
- 500 people
- Sponsor
- Hasselt University
Atrial Fibrillation (AF)
Episodic Future Thinking to Improve Anticoagulant Adherence in Atrial Fibrillation
The purpose of this study is to assess the effectiveness of Episodic Future Thinking (EFT) on improving medication adherence in atrial fibrillation (AF) patients taking oral anticoagulants.
- Trial name
- NCT07174778
- Testing
- Episodic future thinking, attention control
- Where
- 2 sites in China
- Volunteers
- 68 people
- Sponsor
- Jiawen You
Persistent Atrial Fibrillation, Long-standing Persistent Atrial Fibrillation
Pulmonary Vein Antrum Isolation (PVAI) Plus Scar Homogenization and Non-PV Triggers Ensure Long-term Recurrence-free Survival in Non-paroxysmal Atrial Fibrillation
This study aims to examine the long-term success rate of catheter ablation in non-paroxysmal atrial fibrillation patients using different ablation strategies such as : (i) pulmonary vein antrum isolation (PVAI) + isolation of…
- Trial name
- TANTRA (NCT01672138)
- Testing
- Pulmonary Vein Antrum Isolation, scar homogenization, Non-PV triggers ablation
- Where
- 2 sites in United States
- Volunteers
- 186 people
- Sponsor
- Texas Cardiac Arrhythmia Research Foundation
Atrial Fibrillation, GI Bleeding
Left Atrial Appendage Closure With WATCHMAN FLX Device in Recurrent Gastrointestinal Bleeding: The GI-FLX Registry
The GI-FLX Registry is intended to create a registry of patients with a history of Atrial Fibrillation (AF) and Gastrointestinal (GI) bleed who will receive Left Atrial Appendage Closure (LAAC) with WATCHMAN FLX device and…
- Trial name
- NCT06052358
- Testing
- LAAC with Watchman FLX device
- Where
- 4 sites in United States
- Volunteers
- 73 people
- Sponsor
- Kansas City Heart Rhythm Research Foundation
Atrial Fibrillation (Paroxysmal), Atrial Fibrillation Recurrent
Atrial Fibrillation Ablation Registry
This is a single centre prospective data registry. In this study atrial conduction characteristics of extended surface Electrocardiograms (esECG), biomarkers and genetic analysis will be performed before ablation, before…
- Conditions
- Atrial Fibrillation (Paroxysmal), Atrial Fibrillation Recurrent, Atrial Fibrillation Common Gene Variants
- Trial name
- AFAB (NCT03075930)
- Testing
- Extended Electrocardiogram, Body surface potential map
- Where
- Netherlands
- Volunteers
- 1,250 people
- Sponsor
- Maastricht University Medical Center
Atrial Fibrillation
Evaluation of Predictive Factors for Recurrence of Persistent Atrial Fibrillation After Ablation
This is a single-center, retrospective, observational study based on data extracted from the medical records of patients who underwent a procedure for persistent atrial fibrillation ablation.
- Trial name
- FAIR (NCT06620575)
- Testing
- Atrial fibrillation ablation
- Where
- France
- Volunteers
- 542 people
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Atrial Fibrillation, Persistent, Atrial Fibrillation Recurrent
A Prospective Study of REPeat Ablation In Patients With Recurrent PERSistent Atrial Fibrillation: Pulmonary Vein Isolation vs. Adjunct Posterior Wall Isolation (REPAIR PERS-AF Study)
This study aims to investigate the best strategy for repeat ablation of recurrent persistent atrial fibrillation (AF) after previous persistent AF ablation involving pulmonary vein isolation (PVI) along.
- Trial name
- REPAIR PERS-AF (NCT06098989)
- Testing
- Radio frequency ablation
- Volunteers
- 150 people
- Sponsor
- Haukeland University Hospital
Ischemic Stroke, Atrial Fibrillation
Cardiac Assessment for Recurrent Stroke Risk Evaluation in Atrial Fibrillation
Background Atrial fibrillation (AF) is the most common cardiac arrhythmia, affecting up to 10% of the elderly. Ischemic stroke is the main complication of AF and cardioembolism is one of the leading causes of ischemic stroke…
- Conditions
- Ischemic Stroke, Atrial Fibrillation, Cerebrovascular Disorders, Brain Diseases
- Trial name
- CARE-AF (NCT06954610)
- Testing
- No intervention
- Where
- Switzerland
- Volunteers
- 500 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Cryptogenic Stroke, Atrial Fibrillation
Incidence and Predictors of Recurrent Stroke in Cryptogenic Stroke Patients With Atrial Fibrillation
Brief Summary: This study aimed to investigate the risk and factors that predict recurrent stroke in patients who initially had a stroke with no clear cause (called cryptogenic stroke) and were later found to have atrial…
- Conditions
- Cryptogenic Stroke, Atrial Fibrillation, Recurrent Ischemic Stroke
- Trial name
- NCT07126184
- Testing
- Extended Cardiac Monitoring
- Where
- Pakistan
- Volunteers
- 109 people
- Sponsor
- Nangarhar University
Pericardial Effusion
Impact of Colchicine Therapy on Arrhythmia Recurrence After Acute Pericardial Effusion
The effects colchicine administration for acute pericardial effusion after radiofrequency catheter ablation (RFCA) of atrial fibrillation on the recurrences of arrhythmia.
- Trial name
- NCT02260206
- Testing
- Colchicine
- Where
- South Korea
- Volunteers
- 20 people
- Sponsor
- Yong Seog Oh
Atrial Fibrillation
Study of RSD1235-SR for the Prevention of Atrial Fibrillation/Atrial Flutter Recurrence
This study is designed to evaluate the safety, tolerability and preliminary efficacy of vernakalant (oral) in subjects with sustained atrial fibrillation of greater than 72 hours and less than 6 months duration
- Trial name
- NCT00267930
- Testing
- Vernakalant (oral)
- Where
- 22 sites in United States, Canada and 2 more
- Volunteers
- 221 people
- Sponsor
- Advanz Pharma