Clinical trials: Augmentation
Labor Fast
Safety Study of Hyoscine N Butyl Bromide in Active Management of Labor
Although Hyoscine N butyl bromide (HBB) is used liberally to facilitate cervical dilatation, there is little and inconclusive data about its efficacy.
- Trial name
- HBB (NCT02098889)
- Testing
- hyoscine-N-butyl bromide(HBB), Saline
- Where
- Turkey (Türkiye)
- Volunteers
- 382 people, healthy volunteers welcome
- Sponsor
- Sisli Hamidiye Etfal Training and Research Hospital
Chronic Posttraumatic Stress Disorder
Enhancing Exposure Therapy for Post-traumatic Stress Disorder
This study is investigating a new brief psychotherapy for post-traumatic stress disorder (PTSD) which, modifies an already proven psychotherapy for PTSD by adding two new components and modifying several others.
- Trial name
- NCT01574118
- Testing
- Revisiting the Trauma memories, Processing the trauma memories, Psychoeducation
- Where
- United States
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Major Depressive Disorder
Creatine Augmentation for Adolescent Females With Treatment-Resistant Major Depressive Disorder
The primary hypothesis is that compared to placebo, 10g of daily creatine monohydrate for eight weeks will be associated with significant increases in frontal lobe phosphocreatine and beta-nucleoside triphosphate (β-NTP)…
- Trial name
- NCT02134808
- Testing
- Creatine
- Where
- United States
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Perry Renshaw
Bone Augmentation
Use of Perforated Barrier Membranes and IPRF Nano- Micro Sticky Bone
Comparing amount of horizontal bone gain 4 months after alveolar ridge augmentation using IPRF Nano- micro Sticky Bone with perforated collagen membrane versus occlusive barrier membrane by : 1.
- Trial name
- NCT04775940
- Testing
- Perforated collagen membrane, Occlusive collagen membrane
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Cheek Augmentation
Study to Evaluate Satisfaction After Treatment With Restylane
Open-label, phase IV, post-marketing study to evaluate aesthetic improvement and satisfaction after treatment with Restylane
- Trial name
- NCT04638816
- Testing
- Restylane Volyme, Restylane Lyft Lidocaine
- Where
- 3 sites in Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Sinus Floor Augmentation, Maxillary Sinus Floor Elevation
Evaluation of Lateral Sinus Floor Elevation Using Xenograft Versus L-PRF Block Combined With Xenograft
Rehabilitation of the posterior maxilla with dental implants is frequently complicated by insufficient residual bone height resulting from alveolar ridge resorption and maxillary sinus pneumatization.
- Conditions
- Sinus Floor Augmentation, Maxillary Sinus Floor Elevation, Sinus Lift, Xenograft
- Trial name
- NCT07677007
- Testing
- Lateral sinus lift with Xenograft Alone, Lateral sinus lift using L-PRF Block + Xenograft
- Where
- United Arab Emirates
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gulf Medical University
Patients with Posterior Maxillary Atrophy and Need for Sinus Lift Surgery to Allow Implant Placement
Efficacy of L-PRF Against Deproteinized Bovine Mineralized Bone (DBBM)
Objective: The main objective of this study is to evaluate whether the use of L-PRF combined with deproteinized bovine mineralized bone (DBBM; BioOss, Geistlich Pharma®) reduces healing time, through histomorphometric analysis…
- Trial name
- NCT06686836
- Testing
- Sinus lift augmentation with bone substitute (Bio-Oss), Open sinus lift surgery lift using Platelet- and leukocyte-rich fibrin (L-PRF) mixed with a bone substitute (Bio-Oss®(Geistlich AG, Wolhusen, Switzerland)) - L-PRF Block
- Where
- Spain
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Bone Deformity
The Influence of 3D Surgical Template on the Contour of Bone Augmentation, in Patient With Labial Alveolar Ridge Defect and Simultaneous Implantation
Evaluate the impact of using 3D surgical template with guided bone regeneration technique on the contour of bone augmentation in patients with horizontal labial ridge defect and simultaneous implantation.
- Trial name
- NCT06312384
- Testing
- 3D Surgical Template on the Contour of Bone Augmentation, in Patient With Labial Alveolar Ridge Defect and Simultaneous Implantation, conventional guided bone regeneration,in Patient With Labial Alveolar Ridge Defect and Simultaneous Implantation
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Tooth Loss
Ridge Preservation Comparing Simultaneous vs. Delayed Grafting
Comparison of the clinical healing of simultaneous vs. delayed grafting for dental implant placement.
- Trial name
- NCT03580798
- Testing
- Delayed graft, Simultaneous graft
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Louisville
Bone Loss in Jaw, Edentulous Alveolar Ridge
BMAC on PCL Scaffold for Ridge Augmentation
BMAC is used on 3D printed PCL scaffold for horizontal ridge augmentation in aesthetic zone , BMAC contains MSCs which can differentiate in osteogenic medium into osteoblasts which can lay down bone
- Trial name
- NCT05241548
- Testing
- BMAC on PCL Scaffold
- Where
- Egypt
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Cairo University
Bone Resorption
Posterior Maxillary Ridge Augmentation With Sinus Lift Using Mineralized Plasmatic Matrix Versus Autogenous Bone Graft
Using growth factors obtained from patient's venous blood mixed with particulate autogenous bone the study compares bone gain by implant with gold standards in sinus Lift procedures for future implant insertion.
- Trial name
- MPM (NCT03014388)
- Testing
- autogenous bone, Mineralized plasmatic matrix
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cardiovascular Diseases, Insulin Sensitivity/Resistance
VITAL-IMPACT: Improving Cardiometabolic Health in Black Individuals Through Therapeutic Augmentation of Cyclic Guanosine Mono-Phosphate Signaling Pathway
This study investigates the potential of vericiguat, a soluble guanylate cyclase stimulator, to improve cardiometabolic health in obese Black individuals with insulin resistance by directly enhancing cyclic guanosine…
- Conditions
- Cardiovascular Diseases, Insulin Sensitivity/Resistance, Metabolic Disease, Metabolism
- Trial name
- VITAL-IMPACT (NCT06320951)
- Testing
- Vericiguat 10 MG, Insulin Sensitivity Test, Resting Energy and Exercise Energy Expenditure Assessment
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Mid-facial Volume Deficit Related to Aging
Safety and Effectiveness of Juvéderm® VOLUMA XC Injectable Gel for Cheek Augmentation
Multicenter, single-blind, randomized, "no-treatment" control study to demonstrate the safety and effectiveness of VOLUMA XC for deep injection for cheek augmentation to correct age-related volume deficit in the mid-face.
- Trial name
- NCT00978042
- Testing
- Juvéderm® VOLUMA XC
- Where
- 2 sites in United States, Canada
- Volunteers
- 345 people, healthy volunteers welcome
- Sponsor
- Allergan
Breast Augmentation, Breast Reconstruction
NATRELLE® 410 Full and Moderate Height/Projection Breast Implant Continued Access Post-Approval Study
Post-approval study of the safety and effectiveness of NATRELLE® 410 Highly Cohesive Anatomically Shaped Silicone-Filled Breast Implants (Styles 410 FM, FF, MM, or MF) for breast augmentation, reconstruction, or revision
- Conditions
- Breast Augmentation, Breast Reconstruction, Breast Implant Revision
- Trial name
- NCT01853605
- Testing
- Anatomically shaped silicone gel-filled breast implants
- Where
- United States
- Volunteers
- 3,811 people, healthy volunteers welcome
- Sponsor
- Allergan
Wrinkles Such as Nasolabial Folds
Post Market Study of Safety and Performance of RefillHA Volume+ for Facial Soft Tissue Augmentation and Correction of Wrinkles and Folds
This post market study was designed to collect clinical data regarding the safety and performance of RefillHA Volume+ upon its launch, from patients treated with the product in a routine clinical setting of treatments.
- Trial name
- NCT07109635
- Where
- Israel
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Glyance
Alveolar Bone Resorption, Sequela
Bone Material Comparison in Maxillary Sinus Augmentation
Hard and soft tissue deficiencies of an alveolar ridge arise as sequelae of tooth extraction when socket preservation is not applied.
- Conditions
- Alveolar Bone Resorption, Sequela, Tooth Extrusion
- Trial name
- NCT04433117
- Testing
- Shefabone, Bio-Oss
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Mohanad Al-Sabbagh
Breath Test, Oesophageal Cancer
Augmentation of Volatile Biomarkers of Oesophageal and Gastric Adenocarcinoma From the Tumour Lipidome
Nearly 10,000 people die each year in the United Kingdom from cancer of the lower gullet and stomach, known as known as oesophago- gastric adenocarcinoma (OGC).
- Conditions
- Breath Test, Oesophageal Cancer, Gastric Cancer, Augmentation
- Trial name
- AVOCADO (NCT05600608)
- Testing
- Oral Stimulant Drink
- Where
- United Kingdom
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Anuja Mitra
Breast Augmentation
Long-Term Effectiveness of the Motiva Implants® Round and Round Ergonomix
Post-marketing surveillance study to demonstrate the silent rupture rate and satisfaction of patients who underwent a primary and revision breast augmentation surgery with Motiva Implants®, 3 to 10 years before enrollment.
- Trial name
- MIRO (NCT05449587)
- Testing
- MRI and PRO
- Where
- 2 sites in Costa Rica
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Motiva USA LLC
Cognition Improvement, Emotion Regulation
Increasing Mitochondrial Respiration as a Novel Mechanism for Cognitive Augmentation
The purpose of this study is to investigate the effects of increasing brain energy on cognition. The hypothesis is that by using a special kind of light, in combination with a nutritional supplement, it may be possible to…
- Trial name
- MITOCOG (NCT07793604)
- Testing
- Active transcranial photobiomodulation, Active MCT dietary supplementation
- Where
- United States
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Francisco Gonzalez-Lima, PhD
Peri-Implantational Loss, Surgical Wound
Strip Graft w/ Xenogeneic Matrix vs Free Gingival Graft for the Augmentation of Peri-implant Keratinized Mucosa
The primary objective of this study is to compare changes in peri-implant keratinized mucosa (PIKM) following the application of apically repositioned flap (ARF) using a combination of a Strip graft and a Xenogeneic matrix, or…
- Conditions
- Peri-Implantational Loss, Surgical Wound, Healing Surgical Wounds, Thin-gingiva
- Trial name
- NCT06261268
- Testing
- Strip graft with Mucograft, Free gingival graft
- Where
- Spain
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Universidad Complutense de Madrid