Clinical trials: Augmentation, active
Tooth Loss / Rehabilitation, Tooth Extraction
Ovate Pontic Versus Essix Provisional After Tooth Extraction and Alveolar Ridge Preservation (Pontic-Essix)
This randomized controlled trial compares two provisional socket-sealing concepts following single non-molar tooth extraction and alveolar ridge preservation: a fixed, tooth-supported, 3D-printed ovate pontic provisional…
- Conditions
- Tooth Loss / Rehabilitation, Tooth Extraction, Alveolar Bone Loss, Alveolar Ridge Augmentation
- Trial name
- Pontic-Essix (NCT07748871)
- Testing
- Bio-Oss Collagen, Mucograft Seal, Fixed 3D-printed ovate pontic provisional restoration
- Where
- Switzerland
- Volunteers
- 40 people
- Sponsor
- University of Bern
Dental Implant
Hard Tissue Augmentation With or Without Connective Tissue Graft in Immediate Esthetic Implants
This randomized controlled study is aimed to evaluate the esthetic, clinical, and radiographic outcomes following the placement of immediate single-tooth implant with hard and soft tissue augmentation.
- Trial name
- NCT07333534
- Testing
- Immediate dental implant in the esthetic zone
- Where
- Iraq
- Volunteers
- 28 people
- Sponsor
- University of Baghdad
Alveolar Ridge Atrophy
HydroGraft for Mandibular Horizontal Ridge Atrophy Augmentation.
This randomized controlled trial aims to evaluate the efficacy of a hydrogel-enhanced allograft compared with a standard particulate allograft, both used in conjunction with a resorbable collagen membrane, for horizontal alveolar…
- Trial name
- NCT07865299
- Testing
- Control Arm (Allograft + Collagen Membrane), Study Arm (Hydrogel-enhanced Allograft + Collagen membrane)
- Volunteers
- 18 people
- Sponsor
- Damascus University
Device Safety
Adaptive Study to Assess the Safety and Functioning of Motiva Devices on Minimally Invasive Gluteal Augmentation
The objective of this clinical trial is to assess the initial performance and safety of Motiva® Ergonomix2® Diamond®, Motiva Injector®, Motiva® Inflatable Balloon, Motiva® Reusable Channel Dissector, and Motiva® GEM Channel…
- Trial name
- GEM (NCT07135011)
- Testing
- Primary gluteal enhancement
- Where
- Costa Rica
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Establishment Labs
Breast Cancer, Breast Reconstruction
Implant-based Breast Reconstruction in Post-bariatric Women - a Registry-based National Study
The goal of this national registry-based study is to investigate the prevalence of reconstructive breast surgery and risk factors for surgical complications in women who have had weight loss surgery previously.
- Conditions
- Breast Cancer, Breast Reconstruction, Bariatric Surgery, Breast Implant
- Trial name
- NCT07059104
- Testing
- Breast augmentation, Breast reconstruction after mastectomy
- Where
- Sweden
- Volunteers
- 20,000 people
- Sponsor
- Vastra Gotaland Region
Prolonged Labor, Labor Dystocia
Efficacy of Bicarbonate on the Risk of Assisted Delivery in Nulliparous Women With Prolonged Labour
The goal of this clinical trial is to learn if oral bicarbonate can treat prolonged labour in nulliparous women with prolonged labour.
- Trial name
- ProLabour (NCT07321379)
- Testing
- Sodium bicarbonate
- Where
- 3 sites in Denmark
- Volunteers
- 1,520 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Horizontal Alveolar Ridge Deficiency
Autogenous and Xenograft Bone Mix in Alveolar Ridge Reconstruction
Following a tooth extraction, the loss of alveolar bone is inevitable. As the site remodels, the alveolar ridge naturally shrinks in both height and width (Schropp et al., 2003).
- Trial name
- NCT07883603
- Testing
- 25% Autogenous + 75% Xenograft, 50% Autogenous + 50% Xenograft
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- salah mohamed mohamed ibrahim ibrahim
Alveolar Ridge Augmentation
PeptiCol EZgraft in the Extraction Socket Preservation Process After Tooth Extraction
This clinical trial aims to compare the efficacy and safety of applying "PeptiCol EZgraft" in extraction socket preservation procedures against "Regenomer," in terms of reducing the amount of alveolar bone change during the…
- Trial name
- NCT06783660
- Testing
- Peptide-loaded collagen sponge and collagen gel complex, Collagen sponge
- Where
- South Korea
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- NIBEC Co., Ltd.
Alveolar Bone Resorption, Alveolar Ridge Trauma
Vertical Ridge Augmentation Strategies
Guided Bone Regeneration (GBR) is an invaluable and beneficial surgical technique adopted when there is the need to augment an alveolar atrophy.
- Conditions
- Alveolar Bone Resorption, Alveolar Ridge Trauma, Alveolar Bone Loss, Complication of Surgical Procedure
- Trial name
- VARGAS (NCT06242782)
- Testing
- VRA + d-PTFE membrane, VRA + e-PTFE membrane, VRA + customised Ti-mesh
- Volunteers
- 148 people
- Sponsor
- University College, London
Dental Crowding, Gingival Recession
Evaluating the Clinical Efficacy of Collagen Scaffold (Ossix VOLUMAX) With Piezo-Surgical Decortication in Enhancing Orthodontic Treatment Outcomes: A Randomized Controlled Trial
Recent advances in orthodontic treatment have explored various materials to enhance treatment efficacy, particularly focusing on collagen scaffolds.
- Conditions
- Dental Crowding, Gingival Recession, Thin Phenotype
- Trial name
- NCT07097714
- Testing
- Piezocision with ribose cross-linked collagen matrix (Ossix® Volumax), control
- Where
- Russia
- Volunteers
- 70 people
- Sponsor
- NMSI DENTMASTER
Horizontal Alveolar Ridge Deficiency
Comparison of Three Autogenous Bone and Xenograft Ratios for Horizontal Ridge Augmentation
This study will compare three different ratios of autogenous bone and xenograft used for horizontal alveolar ridge augmentation in patients with insufficient bone width for dental implant placement.
- Trial name
- NCT07869485
- Testing
- 50:50 Autogenous Bone-Xenograft, 75:25 Autogenous Bone-Xenograft, 25:75 Autogenous Bone-Xenograft
- Volunteers
- 45 people
- Sponsor
- Eslam hisham mohamed
Peri-implant Mucositis
Impact of Keratinized Mucosa Augmentation on Treatment Outcomes of Peri-implant Mucositis
This study aims to observe the effects of keratinized mucosa width on peri-implant tissues by evaluating clinical and biochemical parameters.
- Trial name
- NCT06305000
- Testing
- Non-surgical treatment, Free gingival graft
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Biruni University
Alveolar Ridge Deficiency
Custom-Made PEEK Versus PTFE Membranes in Maxillary Alveolar Ridge Augmentation
This randomized controlled clinical study aims to evaluate and compare the effectiveness of custom-made polyether ether ketone (PEEK) membranes versus polytetrafluoroethylene (PTFE) membranes in guided bone regeneration for…
- Trial name
- NCT07679451
- Testing
- Custom-made PEEK Membrane, PTFE Membrane
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Mansoura University
Postoperative Pain After Breast Augmentation Surgery, Postoperative Analgesia
Effect of Adding Ultrasound-Guided PECS II Block to Standard Multimodal Analgesia in Breast Augmentation Surgery
This randomized, controlled clinical study will evaluate the effect of an ultrasound-guided PECS II block on postoperative pain control in patients undergoing elective augmentation mammoplasty.
- Trial name
- NCT07879053
- Testing
- Ultrasound-Guided PECS II Block, Standard multimodal analgesia
- Volunteers
- 50 people
- Sponsor
- Ergun Gunduz
Breast Augmentation and Breast Reconstruction, Mammaplasty
Clinical Study on Tissue Preservation in Breast Augmentation and Reconstruction
This clinical study aims to evaluate the safety and effectiveness of advanced, minimally invasive techniques for breast augmentation and reconstruction.
- Conditions
- Breast Augmentation and Breast Reconstruction, Mammaplasty, Breast Augmentation, Tissue Preservation
- Trial name
- NCT07623564
- Testing
- Mia Harmonization, Mia Scarless Lift, Mia Reconstruction
- Where
- Costa Rica
- Volunteers
- 60 people
- Sponsor
- Establishment Labs
OESOPHAGO-GASTRIC CARCINOMA, Oesophageal Adenocarcinoma
AUGMENTED RESPONSE OF VOLATILE BIOMARKERS IN THE ASSESSMENT OF OESOPHAGOGASTRIC CANCER (AROMA2)
Cancer of the stomach and oesophagus is among the world's top five cancers. Survival rates are very poor as the disease presents late and early symptoms are non-specific.
- Conditions
- OESOPHAGO-GASTRIC CARCINOMA, Oesophageal Adenocarcinoma, Gastric Adenocarcinoma and Gastroesophageal Junction Adenocarcinoma, Oesophageal Cancer Nos
- Trial name
- AROMA2 (NCT07260734)
- Testing
- Breath Test
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Imperial College London
Degenerative Lumbar Disease
Comparing Lumbar Fusion With and Without Stress Endplate Augmentation in Patients With Low Bone Mass
Degenerative lumbar disease can cause back pain, leg pain, and difficulty with daily activities. Some patients require lumbar fusion surgery.
- Trial name
- NCT07891663
- Volunteers
- 300 people
- Sponsor
- Xuanwu Hospital, Beijing
Spine Injury, Cord Injury, Spinal
The Outcome of Injured Cervical Spinal Cord With Uncontrolled Swelling Under Duraplasty
Overall Objective: To assess whether incorporating duraplasty alongside bony decompression enhances motor function outcomes in individuals following Traumatic Spinal Cord Injury (TSCI).
- Conditions
- Spine Injury, Cord Injury, Spinal, Cord Infarction Spinal, Incomplete Spinal Cord Injury
- Trial name
- NCT06552507
- Testing
- Duroplasty
- Where
- Taiwan
- Volunteers
- 104 people, healthy volunteers welcome
- Sponsor
- Chang Gung Memorial Hospital
Spine Metastases, Bone Pain
Radiofrequency Ablation/Bone Augmentation + Radiotherapy vs Radiotherapy Alone
This is a single-center, randomized controlled pilot study of radiofrequency ablation and bone augmentation (RFA/BA) plus radiotherapy (RT) vs. RT alone in patients with metastatic T5-L5 disease of the spine.
- Trial name
- NCT07090122
- Testing
- Radiofrequency ablation and bone augmentation with radiotherapy, Radiotherapy alone
- Where
- United States
- Volunteers
- 36 people
- Sponsor
- University of Minnesota
Degenerative Disc Disease (DDD)
HYDRAFIL-D: HYDRogel Augmentation For Intervertebral Lumbar Discs
A multi-center, prospective, dual arm, randomized, controlled pivotal study to evaluate the safety and effectiveness of the ReGelTec HYDRAFIL™ System.
- Trial name
- HYDRAFIL-D (NCT06011551)
- Testing
- The ReGelTec HYDRAFIL™ System, Conservative Care Management
- Where
- 16 sites in United States, Canada
- Volunteers
- 225 people
- Sponsor
- ReGelTec, Inc.