Clinical trials: Autism
Anxiety, Autism Spectrum Disorder
The Effect of Aroma on Anxiety Among Children With Autism.
This study evaluates the effects of essential oils on anxiety scores among children who have an autism spectrum disorder. One third of the children will receive a control blend of oils, one third of the children will receive a…
- Trial name
- NCT03489811
- Testing
- Test Essential Oil Blend, Active Essential Oil Blend, Control Blend
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Nutraceuticals Research Institute
Autism Spectrum Disorder, Social Communication Challenges
Promoting Inclusive Educational Environments for Children with Autism and Other Social-communication Challenges: Preschool Class and Primary School
This study evaluates the effect of using the Autism Program Environment Rating Scale (APERS) as the foundation for providing feedback, in-service training and coaching to teachers, to improve program quality for autistic (ASD)…
- Trial name
- NCT05509309
- Testing
- APERS-based model
- Where
- Sweden
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Stockholm University
Autism Spectrum Disorders
Replication of the The Multi-Media Social Skills Project for Adolescents With Autism Spectrum Disorders
The objective of this study is to validate a social skills training program manual for adolescents (ages 13-17) with Asperger's Syndrome or high functioning autism.
- Trial name
- NCT01836965
- Testing
- Social Skills Intervention
- Where
- United States
- Volunteers
- 155 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Autism Spectrum Disorder, Autism
Mitochondrial Dysfunction in Autism Spectrum Disorder
Researchers at Arkansas Children's Hospital Research Institute are conducting a study about mitochondrial function in children. The study involves up to 5 visits to Arkansas Children's Hospital with fasting blood draws…
- Conditions
- Autism Spectrum Disorder, Autism, Mitochondrial Disease, Developmental Delay
- Trial name
- Mito (NCT02000284)
- Where
- United States
- Volunteers
- 297 people, healthy volunteers welcome
- Sponsor
- University of Arkansas
Autistic Disorder
A Trial to Assess the Efficacy and Safety of Medical Grade Cannabis in Children Diagnosed With Autism Spectrum Disorder
This single center, double-blinded, randomized, placebo-controlled crossover trial will assess the efficacy and safety of extraction of cannabis flowers dissolved in olive oil (30% CBD and 1.5% Δ9-THC) vs.
- Trial name
- NCT05413187
- Testing
- Medical Grade Cannabis oil
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- TO Pharmaceuticals
Autistic Disorder
Proteomic Biomarker Tests in Blood Samples from Children with Autism Spectrum Disorder (ASD)
Behavioral testing is the gold standard for diagnosing autism spectrum disorder (ASD). These tests, including ADOS and ADI-R, are subjective, require trained staff to administer, are time-consuming, and can only be administered…
- Trial name
- NCT02168868
- Testing
- Blood draw, Stool Sample Collection, Urine Sample Collection
- Where
- Israel
- Volunteers
- 900 people, healthy volunteers welcome
- Sponsor
- Benjamin Gesundheit
Autism, Fragile-X Syndrome (FXS)
Glutaminergic Transmission in Autism : Molecular Imaging Exploration
Glutamatergic transmission exploration using PET (Positron Emission Tomography) imaging in autism compared to Fragile-X Syndrome ( FXS) and Healthy Volunteers
- Conditions
- Autism, Fragile-X Syndrome (FXS), Healthy Volunteers
- Trial name
- TANGAU (NCT02719951)
- Testing
- [18F]FPEB PET imaging, Biological samples, MRI
- Where
- France
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- University Hospital, Tours
Stress
CBCT for Parents of Children With Autism
The purpose of this study is to determine if caregivers of children with a developmental delay experience a decrease in stress by participating in a meditation/cognitive training protocol.
- Trial name
- NCT02574559
- Testing
- Cognitive Based Compassion Training Session: Developing Attention and Stability of Mind, Cognitive Based Compassion Training Session: Cultivating Insight into the Nature of Mental Experience, Cognitive Based Compassion Training Session: Self-compassion
- Where
- 2 sites in United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Emory University
Autism Spectrum Disorder, Healthy
Differences in Prosocial Behaviors and Related Brain Networks in Children With Autism and Typical Development
The goal of this observational study is to compare the brain functional network between children with autism and typical development, using magnetic resonance imaging (MRI), electroencephalogram/event-related potentials(EEG/ERPs)…
- Trial name
- NCT06908174
- Testing
- ADOS-2
- Where
- China
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Children's Hospital of Fudan University
Obsessive Compulsive Disorder, Autism Spectrum Disorder
Internet Delivered CBT for OCD in Adolescents With ASD - A Clinical Case Series
The aim of this study is to test the feasibility and acceptability of an internet-delivered cognitive behavior therapy (ICBT) intervention originally developed for neurotypical adolescents with obsessive compulsive disorder (OCD)…
- Trial name
- NCT02660099
- Testing
- Internet-delivered Cognitive Behavior Therapy
- Where
- 2 sites in Sweden
- Volunteers
- 4 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Autism Spectrum Disorder, Restricted Behavior
Modified Pivotal Response Treatment for Insistence on Sameness in Autistic Youth
The purpose of this open label trial is to examine the preliminary feasibility, acceptability, and effectiveness of a 12-week behavioral intervention program (1 hour/week) to treat insistence on sameness (e.g., difficulty…
- Conditions
- Autism Spectrum Disorder, Restricted Behavior, Autism
- Trial name
- M-PRT-IS (NCT06362733)
- Testing
- Modified Pivotal Response Treatment for Insistence on Sameness in Autistic Youth
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Stanford University
Healthy
Effects of Oxytocin Dose Frequency on Behavioral and Neural Responses
The main aim of the study is to examine effects of different dose frequencies of repeated oxytocin administration on neural and behavioral markers of oxytocin in healthy male subjects.
- Trial name
- NCT03610919
- Testing
- Nasal Sprays
- Where
- China
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Electronic Science and Technology of China
Autism Spectrum Disorder
Intranasal Ketamine With Dexmedetomidine for the Treatment of Children With Autism Spectrum Disorder
Autism spectrum disorder (ASD) is a life-long neurodevelopmental disorder characterized by qualitative abnormalities in reciprocal social interactions and patterns of communication, and by a restricted, stereotyped, repetitive…
- Trial name
- NCT03434366
- Testing
- ketamine and dexmedetomidine, ketamine, Saline
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Autism Spectrum Disorder (ASD
Exploring the Physiological Mechanisms of Austism Through Organoids
Autism Spectrum Disorder (ASD) is a neurodevelopmental disorder affecting approximately 1% of the population, characterized by difficulties with social interaction and communication.
- Trial name
- EXPECT HYPE (NCT07494331)
- Where
- France
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Communication Disorder, Childhood, Autism
Evaluating Georgia Part C Implementation Outcomes
This study aims to answer the question: What is the best way to help Early Intervention (EI) providers deliver high-quality services to children with communication delays for autism? The primary goal of this project is to examine…
- Trial name
- NCT07148258
- Testing
- Project ImPACT Training As Usual, Project ImPACT Training Plus Co-Production, Routine Project ImPACT
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Emory University
Depressive Disorder, Major, Bipolar Disorder
Characterization of the Prosocial and Prosexual Effects of GHB
The purpose of this study is to determine whether gamma-Hydroxybutyrate (GHB) has prosocial and prosexual effects in healthy male participants, and to characterize these putative effects via behavioral tests, functional magnetic…
- Conditions
- Depressive Disorder, Major, Bipolar Disorder, Autistic Disorder
- Trial name
- NCT02342366
- Testing
- GHB 35 mg/kg p.o., GHB 20 mg/kg p.o.
- Where
- Switzerland
- Volunteers
- 19 people, healthy volunteers welcome
- Sponsor
- University of Zurich
Intellectual Disability, Neurodevelopmental Disorders
Physical Activity and Community EmPOWERment Project
Purpose: Conduct a wait-list randomized controlled trial (RCT) of an inclusive physical activity program called PACE for adults with intellectual disability (ID) who are not yet showing signs of Alzheimer's Disease…
- Conditions
- Intellectual Disability, Neurodevelopmental Disorders, Autism Spectrum Disorder, Down Syndrome
- Trial name
- PACE (NCT06740162)
- Testing
- PACE Program
- Where
- 2 sites in United States
- Volunteers
- 376 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Chapel Hill
Autism
Motor Function Assessment and VR-based Motor Training in Adults With Autism Spectrum Disorder
The goal of this clinical trial is to learn if autism affect motor functions, including muscle strength, balance, and motor control? Additionally, understanding the motor functions, cognitive functions, and brain activation in…
- Trial name
- NCT07134569
- Testing
- VR-based motor training
- Where
- Taiwan
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Autism Spectrum Disorder, Autism
Using Serious Games to Improve Social Skills in Autism
The investigators will conduct a small-scale randomized control trial comparing the intervention game to an active control game, and will assess outcomes at multiple time points (pre-, post-, 6-month follow-up).
- Trial name
- SAGA (NCT03690661)
- Testing
- Intervention Video Game
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- Penn State University
Autism Spectrum Disorder
An SRT Model for Early Access to ASD Intervention
This project will implement and evaluate an innovative healthcare service delivery model designed to promote earlier access to specialized intervention for toddlers with ASD.
- Trial name
- NCT02409303
- Testing
- Screen-Refer-Treat Intervention
- Where
- United States
- Volunteers
- 627 people, healthy volunteers welcome
- Sponsor
- University of Washington