Clinical trials: Basic Physiology
Amblyopia, Anisometropic, Pediatric
Multimodal Therapy in Anisometropic Amblyopia
This study aims to evaluate whether a six-month app-based visual therapy program, called AmblyoPlay, can improve visual acuity, oculomotor skills, and balance in children with anisometropic amblyopia (a type of "lazy eye" caused…
- Conditions
- Amblyopia, Anisometropic, Pediatric, Postural Balance, Vision Therapy
- Trial name
- MUTA (NCT07093840)
- Testing
- AmblyoPlay Digital Visual Therapy, control group
- Where
- Turkey (Türkiye)
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Yusa Basoglu
Renal Insufficiency, Healthy Volunteers
Pharmacokinetics, Dialysability and Safety of P03277 in Healthy Volunteers and in Patients With Impaired Renal Function
This is an open-label, non-randomized, successive cohorts design, multicenter, single dose phase I study. The primary objectives are: to evaluate the pharmacokinetics (plasma and urine) profile of P03277 following single…
- Trial name
- NCT03657784
- Testing
- P03277
- Where
- 2 sites in Moldova, Romania
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Guerbet
Physical Activity, Aerobic Fitness
Active School. A School-based Intervention to Increase Childrens Daily Physical Activity Level.
This study seeks to explore whether increased physical activity in school affects children's executive function, aerobic Fitness and childrens self-regulation. The "Active school" study was a 10-month randomized controlled trial.
- Conditions
- Physical Activity, Aerobic Fitness, Executive Function
- Trial name
- NCT03436355
- Testing
- Physical activity
- Volunteers
- 449 people, healthy volunteers welcome
- Sponsor
- University of Stavanger
Virtual Reality Therapy
Effects of VR-Based Exergames on Physical and Cognitive Health in Sedentary Workers
Sedentary behavior in the workplace is associated with declines in both physical and cognitive health. Traditional exercise programs are often difficult to sustain among workplace employees, leading to an increased interest in…
- Trial name
- VR-Exergame (NCT07192562)
- Testing
- Virtual Reality-Based Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medipol University
Smoking Cessation, Smoking
Usefulness of Supportive SMS in Addition to an Internet Based Quit Smoking Program (Www.Slutta.no)
The purpose of the study is to investigate the effectiveness of a smoking cessation intervention delivered through a technological web based platform (www.slutta.no) with or without a supportive SMS function.
- Trial name
- NCT01103427
- Testing
- Internet-based behavioral coaching, SMS based coaching, SMS coaching - UNN recruited
- Where
- Norway
- Volunteers
- 4,300 people, healthy volunteers welcome
- Sponsor
- University of Tromso
Aging Well
Online Group-based Dual-task Training to Improve Cognitive Function of Community-dwelling Older Adults
Objectives: This study aims to explore the feasibility, acceptance, and efficacy of online group-based dual-task training as an intervention for improving cognitive function among community-dwelling older adults.
- Trial name
- NCT05573646
- Testing
- Dual-task training, Attention Control
- Where
- Hong Kong
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Neurologic Manifestations, Neurobehavioral Manifestations
Training Cognitive Control Processes in Older Adults
Control processes are classes of brain activity that initiate, coordinate, synchronize, and regulate elemental cognitive functions for the conduct of goal-directed behavior.
- Trial name
- NCT00586638
- Testing
- Video game based training
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Columbia University
Breast Cancer, Lymphoma
The Effects of Anthracycline-based Chemotherapy on Peripheral Vascular Function
The overall goal of this project is to determine the effects of anti-cancer chemotherapy on reflex control of blood pressure and vascular function.
- Conditions
- Breast Cancer, Lymphoma, Chemotherapy Effect
- Trial name
- NCT03062878
- Testing
- Arterial blood pressure, Vascular Ultrasound, Venous blood sample
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Carl Ade, M.S., Ph.D.
Allogeneic Hematopoietic Stem Cell Transplantation (HSCT), Oxygen Deficiency
Impact of Closed PBSC Collection With Reduced Gas-Phase Oxygen Exposure on Graft Quality and Early Engraftment in Allo-HSCT
This study aims to establish a closed PBSC collection procedure with reduced gas-phase oxygen exposure and to verify its impact on graft functional quality and clinical engraftment efficiency.
- Conditions
- Allogeneic Hematopoietic Stem Cell Transplantation (HSCT), Oxygen Deficiency, Graft Function
- Trial name
- NCT07904234
- Testing
- Closed PBSC collection with reduced gas-phase oxygen exposure
- Where
- China
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Institute of Hematology & Blood Diseases Hospital, China
Peripheral Arterial Disease, Endothelial Dysfunction
Effects of Combined Aerobic and Resistance Training in Patients With Intermittent Claudication
Exercise training improves walking capacity and regional perfusion in patients with Intermittent Claudication (IC). Endothelial Progenitor Cells (EPCs) and Endothelial Microparticles (EMPs) could play an important role in this…
- Trial name
- NCT04302571
- Testing
- combined aerobic and resistance physical activity
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University Of Perugia
Chronic Obstructive Pulmonary Disease, Self Efficacy
Effect of Education and Tele-consultancy Intervention Based on Watson Human Care Theory Individuals With COPD
This study aims to investigate the effect of education and tele-consultancy intervention based on Watson's Human Care Theory on self-efficacy and quality of life of individuals with COPD.
- Conditions
- Chronic Obstructive Pulmonary Disease, Self Efficacy, Quality of Life, Pulmonary Function
- Trial name
- NCT04256070
- Testing
- education and tele-consultation
- Where
- Turkey (Türkiye)
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Akdeniz University
Developmental Coordination Disorder
Motor-Cognitive Integrated Intervention for Children With Developmental Coordination Disorder
The goal of this clinical trial is to evaluate the efficacy of an Action Observation and Motor Imagery (AOMI) combined with Fundamental Movement Skills (FMS) intervention for children aged 7 to 11 years with Developmental…
- Trial name
- NCT07486856
- Testing
- Action Observation and Motor Imagery (AOMI) Training, Fundamental Movement Skills (FMS) Training, General Physical Activities
- Where
- China
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Shanghai University of Sport
Motor Neuropathy
Stroke Recovery Research Based on EEG-fMRI
This study is aimed to investigate the post-stroke motor recovery of patients with ischemic stroke based on their neural features extracted from EEG-fMRI data.
- Trial name
- EEG-fMRI (NCT05427422)
- Testing
- MRI recording, EEG recording
- Where
- China
- Volunteers
- 147 people, healthy volunteers welcome
- Sponsor
- Xi'an Jiaotong University
Taste Sensitivity, Umami Taste Perception
Umami Taste Intensity and Meal Intake
Sweet and salty tastes can influence food intake. Increased intensity of these tastes has been shown to decrease food intake and increase satiation compared to the less intense taste, independent of palatability.
- Conditions
- Taste Sensitivity, Umami Taste Perception, Food Intake Regulation, Hedonic Function
- Trial name
- OptUmami (NCT07421466)
- Testing
- Hedonic mapping, Ad libitum risotto test meal
- Where
- Netherlands
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- Wageningen University
Postprandial Glucose, Platelet Activation
Cimarrón Bean Extrudate Solution on Platelet Function and Biochemical Parameters
This non-randomized acute clinical trial evaluates the effect of consuming a water-based solution of Cimarrón bean extrudate on platelet function and postprandial glycemia in adults.
- Trial name
- CBE-SP (NCT07043829)
- Testing
- SPVCE (Solution Phaseolus vulgaris L. var. Cimarrón Extrudate in Water)
- Where
- Chile
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Talca
Sex Dysfunction, Breast Cancer
THE IMPACT OF WHATSAPP BASED EX-PLISSIT MODEL SEXUAL COUNSELING ON THE SEXUAL LIVES OF BREAST CANCER SURVIVORS
Cancer is a significant health problem negatively impacting human health due to population growth, aging, and lifestyle changes known to cause cancer.
- Trial name
- NCT07626970
- Testing
- Sexual counseling group based on the EX-PLISSIT Model
- Where
- Turkey (Türkiye)
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Karamanoğlu Mehmetbey University
Frailty, Muscle Loss
A Randomized-Control Study of Gym Tonic's Community Based Strength Training Intervention.
Launched in April 2015 , Gym Tonic is the first of its kind cross-border exercise-as-medicine partnership between research institutions, business enterprises and service providers from Singapore and Finland.
- Conditions
- Frailty, Muscle Loss, Sarcopenia
- Trial name
- NCT04661618
- Testing
- Gym Tonic programme and Gym equipment
- Where
- Singapore
- Volunteers
- 318 people, healthy volunteers welcome
- Sponsor
- PulseSync Pte Ltd
Blood Pressure, Endothelial Dysfunction
Effect of Inorganic Nitrate Supplement on Blood Pressure
The primary purpose of this project is to assess the efficacy (effectiveness) of plant-based nitrate tablets to elevate nitric oxide in your system as measured by saliva and effect on lowering blood pressure (BP), supporting…
- Trial name
- NCT03909789
- Testing
- Plant based bioequivalent Nitrate supplementation
- Where
- United States
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center
Concussion (Diagnosis)
Sports-related Concussion: Physiological, Biomechanical and Cognitive Methodology
The study aims to investigate the changes in physiological, biomechanical and cognitive performance under a traumatic sport-event (i.e., rugby match).
- Trial name
- NCT04841876
- Testing
- rugby matches
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Hong Kong Baptist University
Bariatric Surgery, Abdominoplasty
Effect of a Collagen-containing Supplement on Dermal Collagen Content in Metabolic Bariatric Surgery Patients Undergoing Corrective Aesthetic Surgery: A Randomized, Double-blind, Placebo-controlled Trial
This single-center, randomized, placebo-controlled trial evaluated whether perioperative supplementation with a collagen-based oral formulation affected dermal collagen content and postoperative outcomes in adults aged 18-65…
- Conditions
- Bariatric Surgery, Abdominoplasty, Collagen Synthesis, Skin Physiology
- Trial name
- COLLAGEN (NCT06787924)
- Testing
- Collagen hydrolyzed peptides, Starch
- Where
- Egypt
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- General Committee of Teaching Hospitals and Institutes, Egypt