Clinical trials: Blepharoplasty
Eyelid Diseases
Functional Changes After Upper Blepharoplasty
Upper blepharoplasty is a common eyelid procedure. It associated with visual, cosmetic and functional changes .Investigator will evaluate outcome of this procedure.
- Trial name
- NCT04201925
- Testing
- upper blepharoplasty
- Where
- United Arab Emirates
- Volunteers
- 50 people
- Sponsor
- Benha University
Dermatochalasis
Topical Bimatoprost for Chemical Blepharoplasty
Topical bimatoprost has been shown to cause periorbital changes of soft tissue which are most pronounced when used directly onto the cornea for the treatment of glaucoma.
- Trial name
- NCT02830776
- Testing
- bimatoprost 0.03% ophthalmic solution
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Tulane University
Dermatochalasis of Upper Eyelid, Ptosis, Eyelid
Comparative Study of Ziplyft Treatment vs. Traditional Blepharoplasty for Upper Eyelid Rejuvenation
This study will compare two surgery techniques used for upper eyelid (eyelift) surgery: traditional surgery and a newer method called Ziplyft (a non-powered, hand-held clamp).
- Conditions
- Dermatochalasis of Upper Eyelid, Ptosis, Eyelid, Blepharoplasty
- Trial name
- NCT07250139
- Testing
- Ziplyft Device, Comparator Arm: Standard Blepharoplasty
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Osheru Inc.
Brow Ptosis, Dermatochalasis
Enhancing the Durability of Thread-Assisted Brow Suspension Through Upper Blepharoplasty-Assisted Ligament Release
This prospective clinical study aims to investigate whether combining upper blepharoplasty with limited release of the lateral brow-retaining ligaments improves the long-term effectiveness of barbed thread brow suspension.
- Conditions
- Brow Ptosis, Dermatochalasis, Periorbital Aging
- Trial name
- NCT07879456
- Testing
- Upper Blepharoplasty, Barbed Thread Brow Suspension, Lateral Brow-Retaining Ligament Release
- Where
- Turkey (Türkiye)
- Volunteers
- 90 people
- Sponsor
- Muhammed Mustafa Demirok
Pain, Postoperative, Bruising
Use of Tranexamic Acid in Blepharoplasties
The goal of this investigation is to assess whether or not there is a significant difference in the presence and/or degree of post-operative ecchymosis, pain, and edema between groups of patients undergoing upper lid…
- Trial name
- NCT04724772
- Testing
- Tranexamic acid injection
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Northwestern University
Eyelid Dermatochalasis, Dermatochalasis
Restorative Eye Treatment and INhance in Upper Eyelid Blepharoplasty Surgery
The purpose of this research is to determine if restorative eye treatment (RET) and Inhance with trihex technology used before and after blepharoplasty can lead to better skin quality before undergoing blepharoplasty, and if…
- Trial name
- NCT05007288
- Testing
- Restorative Eye Treatment (RET) cream, INhance with Trihex Technology
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- University of Miami
Eyelid Diseases
Surgical Treatment of Lower Eyelid Involutional Entropion and Dermatochalasis
lower eyelid involutional entropion and dermatochalasis are common associated problems. combined approaches give good results.
- Trial name
- NCT04720586
- Testing
- lower eyelid blepharoplasty , retractor plication and wedge resection, lower eyelid blepharoplasty and retractor plication
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- Benha University
Lipid Thickness
Investigating Abnormal Lipid Layer Thickness in Blepharoplasty Patients
Deficiency in tear film lipid layer thickness (LLT) has been implicated in the development of dry eye symptoms, and is influenced to a significant degree by the anatomy and function of the eyelids.
- Trial name
- NCT01787942
- Testing
- Tear Science LipiView
- Where
- Singapore
- Volunteers
- 60 people
- Sponsor
- Singapore National Eye Centre
Eyelid Diseases
Small Incision Technique Versus Upper Blepharoplasty in Upper Eyelid Medial Pad Fat Removal
Medial upper eyelid pad of fat bulge is a common problem. Small incision surgery could be a time-efficient, minimally invasive and scar formation procedure .
- Trial name
- NCT04689230
- Testing
- upper eyelid blepharoplasty
- Where
- United Arab Emirates
- Volunteers
- 40 people
- Sponsor
- Benha University
Scar, Intercanthal Distance Ratio
Botulinum Toxin to Improve Results in Epicanthoplasty
Medial epicanthal fold is a common skin fold in the inner part of the eye in more than 50% Asia population, giving the illusion of a shorter palpebral fissure length and a wider intercanthal distance.
- Trial name
- NCT03294382
- Testing
- Botulinum toxin type A
- Where
- China
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Shanghai Jiao Tong University School of Medicine
Excess Skin of Both Eyelids, Contrast Sensitivity
The Effect of Upper Blepharoplasty on Vision Quality in the Early Postoperative Period
Contrast sensitivity (CS) and tear film (TF) changes are noted in late postoperative period after upper blepharoplasty (UB), while the same was rarely investigated in the early postoperative period.
- Conditions
- Excess Skin of Both Eyelids, Contrast Sensitivity, Tear Film Insufficiency of Both Eyes, Corneal Topography
- Trial name
- NCT05549713
- Testing
- Upper blepharoplasty
- Where
- Croatia
- Volunteers
- 40 people
- Sponsor
- Osijek University Hospital
Dermatochalasis of Eyelid, Ocular Surface Disease
Short and Long-term Results of Skin Versus Skin Plus Orbicularis Resection Blepharoplasty
This study aims to evaluate the short and long-term effects of skin-only and skin+muscle excision blepharoplasty on corneal nerves, dry eye parameters, meibomian glands, and eyebrow position.
- Conditions
- Dermatochalasis of Eyelid, Ocular Surface Disease, Meibomian Gland Dysfunction, Dry Eye
- Trial name
- NCT05528016
- Testing
- Upper Eyelid Blepharoplasty
- Where
- Turkey (Türkiye)
- Volunteers
- 24 people
- Sponsor
- Marmara University
Dermatochalasis of Upper Eyelid
Does Unilateral Compression Dressing Reduce Postoperative Swelling and Bruising After Upper Eyelid Blepharoplasty?
This study evaluated whether applying a compression dressing to one eyelid after upper eyelid blepharoplasty (eyelid lift surgery) reduces swelling, bruising, and discomfort compared to the untreated eyelid.
- Trial name
- COMPRESS-BLEPH (NCT07701265)
- Testing
- Compression Dressing (CD), No Dressing (Standard Postoperative Care)
- Where
- Turkey (Türkiye)
- Volunteers
- 56 people
- Sponsor
- Fatma Poslu Karademir
Dacryocystorhinostomy, Ectropion
PMCF-study Using Novosyn® Quick Suture Material in Ophthalmic Surgery
The aim of this study is to show that the performance of Novosyn® Quick suture material is comparable with standard suture material used in Ophthalmic surgery.
- Conditions
- Dacryocystorhinostomy, Ectropion, Entropion, Ptosis
- Trial name
- OPHTHALNOQ (NCT02761083)
- Testing
- Novosyn® Quick, Vicryl® Rapid
- Where
- Spain
- Sponsor
- Aesculap AG
Blepharoptosis
Liquid Bandage (2-Octyl-Cyanoacrylate) in Upper Lid Blepharoplasty
The aim of this randomized and masked prospective trial is to compare the effectiveness of Liquid Bandage (Octyl-2-Cyanoacrylate) and 6/0 nylon suture as a wound closure device in upper lid blepharoplasty surgery.
- Trial name
- NCT00816270
- Testing
- Bilateral Upper eyelid blepharoplasty
- Where
- Brazil
- Volunteers
- 11 people
- Sponsor
- Federal University of São Paulo
Subbrow Blepharoplasty;Double Eyelid Surgery； Orbicularis Oculi Muscle
Subbrow Blepharoplasty Combined With Double Eyelid Surgery for Upper Eyelid Rejuvenation in Asian Women
Subbrow blepharoplasty combined with double eyelid surgery excising the subbrow skin and the supratarsal upper eyelid skin, lifting and fixing the OOM flap, meanwhile restoring the natural and symmetrical appearance, is a safe…
- Trial name
- NCT04001660
- Testing
- Subbrow Blepharoplasty Combined with Double Eyelid Surgery
- Where
- China
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Xijing Hospital
Edema Face
Tacrolimus for Malar Edema
Elective lower eyelid surgery is a common cosmetic procedure. Facial swelling is a common complication. Studies suggest that this facial swelling is part of a complex inflammatory process.
- Trial name
- NCT03715387
- Testing
- Tacrolimus Topical 0.1% Topical Ointment, Polysporin Ointment
- Where
- Canada
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Wrinkle Appearance, Melanin Hyperpigmentation
Retrospective Follow-up Study on Lower Eyelid Melanin and Wrinkles After Blepharoplasty for Lower Eyelid Bags
This observational study aims to investigate the long-term outcomes of transconjunctival lower eyelid blepharoplasty, with a specific focus on changes in lower eyelid hyperpigmentation or hypopigmentation and morphological…
- Trial name
- NCT07481695
- Testing
- transconjunctival lower blepharoplasty, POD lifting
- Where
- China
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Peking Union Medical College
Eyelid Diseases, Ptosis, Eyelid
Effect of Upper Eyelid Surgeries on Corneal Characteristics
The goal of this prospective observational study is to learn about the impact of conventional eyelid correction surgery on the eye's health and function in ptosis and eyelid retraction patient.
- Trial name
- NCT05750251
- Testing
- levator muscle resection surgery, Müller's muscle-conjuctival resection surgery, full-thickness anterior blepharotomy surgery
- Where
- Taiwan
- Volunteers
- 13 people
- Sponsor
- National Taiwan University Hospital
Injury Throat
Nasopharyngeal Versus Laryngeal Mask Airway in Anaesthesia for Bilateral Blepharoplasty
General anaesthesia demands securing patient's airway either with endotracheal tube or laryngeal mask (LMA); however, both carry the disadvantage of postoperative soar throat.
- Trial name
- NCT03510949
- Testing
- Nasopharyngeal airway or laryngeal mask airway
- Where
- Egypt
- Volunteers
- 148 people
- Sponsor
- Hala Salah El-Din El-Ozairy