Clinical trials: Blepharoptosis
Ptosis, Eyelid, Conjunctiva Inflamed
The Effect of Upneeq (Oxymetazoline Hydrochloride 0.1%) on Eyelid Position, Eye Redness, and Eye Appearance
The purpose of the research is to see if Upneeq ( oxymetazoline 0.1% ophthalmic solution) has an effect on eyelid position, eye redness, or patient-perceived appearance of the eyes.
- Conditions
- Ptosis, Eyelid, Conjunctiva Inflamed, Eye Manifestations
- Trial name
- NCT04831047
- Testing
- Oxymetazoline hydrochloride 0.1% ophthalmic solution
- Where
- United States
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University of Miami
Dermatochalasis, Blepharoptosis
Vibration-Assisted Anaesthesia
Aim of study is to investigate whether a small, non-invasive vibrating device applied to the forehead during local anaesthetic administration reduces the pain of the injection.
- Trial name
- NCT00793988
- Testing
- Vibration-assisted anaesthesia, Switched-off vibrating device
- Where
- Canada
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Blepharoptosis
Digital Photographs to Evaluate Blepharoptosis
To compare measurements made by a computer software (ImageJ) made on photographs to the traditional clinical measures with a ruler in the evaluation of blepharoptosis
- Trial name
- NCT02367677
- Testing
- Method comparison
- Where
- Canada
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- CHU de Quebec-Universite Laval
Eyelid Diseases, Eyelid Droop
Spacer Graft Study
To determine which of three types of spacer grafts (hard palate vs autologous ear cartilage vs Enduragen) are the most effective in lower eyelid retraction repair outcomes as measured by MRD2 (margin to reflex distance 2)
- Trial name
- NCT04140734
- Testing
- Spacer Graft
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Montefiore Medical Center
Ptosis, Blepharoptosis
Bandage Contact Lens in Post Operative Ptosis Patients
This study is being conducted to determine whether the use of bandage contact lens after ptosis surgery provides any benefits for the patient or is unnecessary.
- Trial name
- NCT03375879
- Testing
- Bandage contact lens
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St. Joseph's Healthcare Hamilton
Recurrent Ptosis of the Breast
Seri Surgical Scaffold Support of the Lower Pole of the Breast
Will the use of an FDA approved highly purified silk scaffold; Seri Surgical Scaffold help shape and hold the breast up on the chest preventing re-stretching and bottoming out of the breast in breast reduction or…
- Trial name
- SeriSupport (NCT02016612)
- Testing
- Seri Surgical Scaffold
- Where
- 2 sites in United States
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Bengtson Center
Eyelid Ptoses
The Effect of Varying Brightness on Palpebral Aperture
We aim to establish the point at which glare from bright lights begins to engage our eyelids - causing us to "squint". We will be using a video camera with an LED ring light around it facing the volunteer and we will record the…
- Trial name
- NCT05210491
- Testing
- Review of eyelid positioning in increasing brightness levels
- Where
- United Kingdom
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Edinburgh
Eyelid Droop
The Effect of Lumify™ Eyedrops on Eyelid Position
The purpose of the research is to see if Lumify™ has an effect on eyelid position.
- Trial name
- NCT03782701
- Testing
- Brimonidine tartrate ophthalmic solution 0.025%, Sterile balanced saline solution
- Where
- United States
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- University of Miami
Ptosis
A Prospective Cohort Study on Visual Function and Psychological Conditions Before and After Surgery for Congenital Ptosis
The goal of this observational study is to learn about the 6-month effects of Levator Resection combined with Fascial Sheath Suspension surgery in patients who undergo this procedure to treat congenital ptosis.
- Trial name
- NCT07534436
- Where
- China
- Volunteers
- 73 people, healthy volunteers welcome
- Sponsor
- Zhongshan Ophthalmic Center, Sun Yat-sen University
Blepharoptosis
Astigmatic Changes Secondary to Eyelid Surgeries
Eyelid surgeries change the lid position over the cornea. Previous surgeries evaluated astigmatic corneal changes in children undergoing ptosis repair.
- Trial name
- NCT01968174
- Where
- 3 sites in Israel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Meir Medical Center
Dermatochalasis of Eyelid, Ptosis, Eyelid
Brimonidine for Intraoperative Hemostasis
The purpose of this study is to observe and report the effects of topical ophthalmic brimonidine in oculofacial plastic surgery.
- Conditions
- Dermatochalasis of Eyelid, Ptosis, Eyelid, Ectropion, Entropion
- Trial name
- NCT05480098
- Testing
- Brimonidine Topical
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Louisville
Blepharoptosis
Comparison of Postoperative Pain With Two Different Types of Local Anesthesia in Surgery for a Drooping Eyelid
Conjunctival Mullerectomy is a well known procedure used to correct upper lid ptosis via a posterior approach. Patients who undergo this procedure are often given local anesthesia to alleviate intraoperative and postoperative…
- Trial name
- NCT01350024
- Testing
- Frontal nerve block with 2% lidocaine with 1:100,000 dilution of epinephrine, Subconjunctival injection of 2% lidocaine with 1:100,000 dilution with epinephrine
- Where
- United States
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Miami
Upper Eyelid Dynamics
Upper Eyelid Dynamics in Pediatric Blepharoptosis Using High Speed Videography
Evaluation of the Upper Eyelid Dynamics in Simple Congenital Blepharoptosis before and after Levator Muscle Resection Using High speed Photography
- Trial name
- NCT06976645
- Testing
- Levator muscle resection
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Minia University
Dermatochalasis, Ptosis, Eyelid
A Comparison of the Effect of Suture Material on Blepharoplasty Incision
The objective is to compare the effect of suture material on blepharoplasty incision. Outcomes of blepharoplasty scar and/or cosmesis will be compared between plain gut and polypropylene suture.
- Trial name
- NCT04585217
- Testing
- Randomized laterality of suture materials for closure (6-0 polypropylene monofilament suture vs fast absorbing gut suture on right eyelid)
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Massachusetts Eye and Ear Infirmary
Blepharoptosis
A Pharmacokinetics (PK) Study in Healthy Adults
This is to characterize STN1013800 active ingredient bioavailability following multiple-dose ocular administration of STN1013800 to both eyes in healthy adults.
- Trial name
- NCT06911216
- Testing
- STN1013800 ophthalmic solution
- Where
- China
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Santen Pharmaceutical Co., Ltd.
Myasthenia Gravis, Fatigue
Capturing Key MG-symptoms Using Smartphone Recordings.
This study will make use of a cross-sectional design of MG patients and non-MG participants to quantitatively assess key MG symptoms, and to explore the applicability of machine learning algorithms to their measurement.
- Trial name
- CAPTURE - MG (NCT06743490)
- Where
- 2 sites in Netherlands
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Leiden University Medical Center
Breast Sagging, Ptosis
Laser Fluorescent Imaging of Nipple and Areola During Breast Lift
Breast lift surgery performed in combination with breast implants is a common cosmetic operation. However, there have been concerns regarding the safety of this treatment combination.
- Conditions
- Breast Sagging, Ptosis, Loss of Breast Volume
- Trial name
- NCT02201979
- Testing
- Vertical breast lift with implants
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- Swanson Center
Blepharoptosis
Saline Injection - Assisted Anesthesia in Eyelid Surgery
The investigators hypothesize that injection of saline to the upper eyelids prior to lidocaine/adrenaline injection will reduce pain of the local anesthetic in comparison to injection of lidocaine alone.
- Trial name
- NCT01239498
- Testing
- Injection of Saline + Lidocaine/Adrenaline, Lidocaine/Adrenaline only
- Where
- 2 sites in Israel
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Epiphora, Ptosis
Bupivacaine Epiphora Trial
The objective of this study is to investigate quantitative improvement in excessive tearing after administration of Bupivacaine, a local anesthetic, into the affected eyelids.
- Trial name
- NCT03266081
- Testing
- 0.75% bupivacaine
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- McMaster University
Blepharoptosis, Ecchymosis; Eyelid
Fibrin Sealant in Eyelid Surgery
This study is looking at the effect of Tisseel in eyelid surgery. Fibrin sealants (Tisseel) cause there to be less bleeding during surgery. Surgeons have used Tisseel for over two decades to reduce bruising.
- Trial name
- NCT05358977
- Testing
- Tisseel
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Calgary