Clinical trials: Blood Glucose Metabolism
Obesity
Effects of Roflumilast on Insulin and Blood Sugar Levels in Prediabetic Overweight and Obese Individuals
Background: Roflumilast is a drug used to treat chronic obstructive pulmonary disease (COPD). It is designed to help reduce lung inflammation.
- Trial name
- NCT01862029
- Testing
- Roflumilast
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Metabolic Syndrome X, Prediabetic State
Education, Counseling, and Drug Therapy to Reduce Symptoms of Metabolic Syndrome
This study will determine the effects of a supplement in reducing symptoms of metabolic syndrome, a collection of symptoms that increase the risk for developing heart disease, stroke, and diabetes.
- Conditions
- Metabolic Syndrome X, Prediabetic State, Insulin Resistance, Obesity
- Trial name
- NCT00129792
- Testing
- Dietary supplement for weight loss, Education and counseling for weight loss
- Where
- United States
- Volunteers
- 79 people
- Sponsor
- Oregon Health and Science University
Cardiovascular Abnormalities, Arterial Blood Pressure
Multicenter Study on Cardiovascular and Metabolic Complications in Patients With Biochemically Silent Pheochromocytomas and Paragangliomas
The aim of the study is to characterise the cardiovascular and metabolic complications pre- and post-surgery of patients with biochemically negative PPGL and to compare them with normal individuals and patients with secreting…
- Conditions
- Cardiovascular Abnormalities, Arterial Blood Pressure, Heart Rate, Congestive Heart Failure Chronic
- Trial name
- NCT07316075
- Where
- Greece
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Laikο General Hospital, Athens
Diabetes Mellitus, Type 2
In-Home Weight Loss Program for Adults With Type 2 Diabetes Delivered by Interactive Cable Television Technology
The majority of patients with Type 2 Diabetes are obese and weight loss is known to improve diabetes outcomes and reduce the need for anti-diabetic medical.
- Trial name
- NCT00277277
- Testing
- Healthium
- Where
- United States
- Volunteers
- 19 people
- Sponsor
- Bastyr University
Blood Pressure, Diabetes
Mitigating the Pro-inflammatory Phenotype of Obesity
The purpose of this study is to examine the hypothesize that 4 weeks of sympathetic nerve activity (SNA) inhibition (oral clonidine) will cause a significant reduction in circulating blood concentrations and endothelial cell…
- Conditions
- Blood Pressure, Diabetes, Obesity, Insulin Resistance
- Trial name
- MAPLE (NCT04934228)
- Testing
- Hydrochlorothiazide 12.5Mg Tab, Clonidine Pill
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- University of Kansas Medical Center
Cardiovascular Diseases, Endothelial Dysfunction
Impact of Consuming Plant Sterols on Endothelial Function and Blood Pressure
The purpose of the research is to assess the impact of co-consuming plant sterols-enriched food product as part of a healthy eating pattern diet on endothelial function (brachial artery FMD, vasodilation-related and…
- Conditions
- Cardiovascular Diseases, Endothelial Dysfunction, Metabolic Syndrome, Diet Modification
- Trial name
- NCT03723330
- Testing
- plant sterols, healthy diet
- Where
- Singapore
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Diabetes Mellitus
Blood Glucose Monitoring Systems: Discounter Versus Brand
This study assesses the system accuracy of 5 blood glucose monitoring systems pursuant to ISO 15197 under the aspect of the system's prospected costs for the user.
- Trial name
- NCT05031000
- Testing
- blood glucose measurement: POCT, blood glucose measurement: reference
- Where
- Germany
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- Institut fur Diabetes Karlsburg GmbH
Diabetes, Diabetes Mellitus, Type 2
Effect of Biphasic Insulin Aspart 30 on Blood Glucose Control in Subjects With Type 2 Diabetes
This trial was conducted in Russian Federation. This trial aimed for a comparison of the effect on glycemic control in subjects with type 2 diabetes of three different treatment regimens: biphasic insulin aspart 30 thrice daily…
- Trial name
- NCT00280046
- Testing
- biphasic insulin aspart
- Where
- 11 sites in Russia
- Volunteers
- 307 people
- Sponsor
- Novo Nordisk A/S
Abdominal Obesity
Effect of Replacing HFCS With Sucromalt in Subjects With Raised Waist Circumference
Weight gain is linked to a high consumption of soft-drinks and other beverages sweetened with high fructose corn syrup. Being overweight increases risk for diabetes and heart disease.
- Trial name
- NCT00374218
- Testing
- High Fructose Corn Syrup, Sucromalt
- Where
- Canada
- Volunteers
- 28 people, healthy volunteers welcome
- Sponsor
- University of Toronto
PreDiabetes, Blood Glucose, High
Investigation of Cinnamon Spice on Glucose Tolerance in Subjects With Pre-diabetes
This study aims to determine whether the effectiveness of cinnamon spice capsules vs. placebo capsules on glucose tolerance in prediabetic subjects who are overweight or obese.
- Trial name
- CINNII (NCT04342624)
- Testing
- Cinnamon
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Prostate Cancer, Resistance Exercise
Androgen Deprivation Therapy Muscle Protein Metabolism and Blood Glucose
Prostate cancer (PCa) patients receiving androgen deprivation therapy (ADT) (e.g., Zoladex), experience troublesome side effects during and after treatment (e.g., loss of lean body mass (LBM) and increased fat mass).
- Conditions
- Prostate Cancer, Resistance Exercise, Androgen Deprivation Therapy
- Trial name
- NCT03440879
- Testing
- Zoladex
- Where
- Norway
- Volunteers
- 23 people
- Sponsor
- Norwegian School of Sport Sciences
Diabetes Mellitus
Comparative Study of a Smartphone-Linked Self-Monitoring System Versus a Traditional One for Improving Metabolic Control and Compliance to Self-Monitoring of Blood Glucose
The purpose of this study is to demonstrate the superiority of iBGstar as a component of the diabetes treatment vs. traditional blood glucose self-monitoring system for improving glycemic control after 6 months in young patients…
- Trial name
- iNew Trend (NCT02073188)
- Testing
- iBGStar, Traditional Glucometer
- Where
- Italy
- Volunteers
- 186 people
- Sponsor
- Sanofi
Type 1 Diabetes
Creation of a Patient Database for Silicon Patient Simulation, Glucose Sensor Variability and Pharmacokinetic Study of Debiotech Jewelpump
The aim this study is the acquisition and management of a data base for the development of the glycaemic regulation algorithms. This database will integrate the measures of blood glucose and the glycaemia level of the Dexcom…
- Trial name
- DiabeloopWP3 (NCT01640223)
- Testing
- Dexcom7
- Where
- 7 sites in France
- Volunteers
- 40 people
- Sponsor
- Centre d'Etudes et de Recherche pour l'Intensification du Traitement du Diabète
Healthy Volunteers, Type 2 Diabetes
A Research Study Comparing Active Drug in the Blood in Healthy Participants Following Dosing of the Current and a New Formulation (C) Semaglutide Tablets
In this study two different tablets for oral use of a known investigational medicinal product, called semaglutide, will be tested.
- Trial name
- NCT04109508
- Testing
- Oral semaglutide
- Where
- Germany
- Volunteers
- 278 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Cardiovascular Risk Factor, Pre Diabetes
Effects of a Workplace Exercise Intervention on Cardio-Metabolic Health
Background: The rising levels of physical inactivity in the Eastern Mediterranean region (43.2%) and in the United Arab Emirates (38%) compared with the global levels of physical inactivity (31.2%) is alarming (6,15).
- Conditions
- Cardiovascular Risk Factor, Pre Diabetes, High Blood Pressure, Elevated LDL Cholesterol
- Trial name
- NCT04403789
- Testing
- Exercise Time, Supervised Group Exercise
- Where
- United Arab Emirates
- Volunteers
- 130 people, healthy volunteers welcome
- Sponsor
- United Arab Emirates University
Essential Hypertension, Metabolic Syndrome
A Clinical Trial to Evaluate the Blood Pressure Control of Telmisartan or Losartan in Essential Hypertensive Patients With Metabolic Syndrome
This is a multi-center, randomized, open-label, active comparator-controlled, phase 4 clinical trial to evaluate the blood pressure control of Telmisartan or Losartan in essential hypertensive patients with metabolic syndrome
- Trial name
- PRISTINE (NCT05843162)
- Testing
- Telmisartan, Losartan
- Volunteers
- 116 people
- Sponsor
- Chong Kun Dang Pharmaceutical
Hyperlipidemia, Impaired Fasting Glycemia
Effects of Hypolipemic Treatment on Adipokines
The study is planned to show whether monotherapies or combined hypolipemic therapy influence the fasting plasma glucose, serum adipokines (leptin, adiponectin, resistin) and proinflammatory cytokines (interleukin-6, TNF alpha)…
- Trial name
- NCT01099176
- Testing
- To compare monotherapies and combined therapy with each other
- Where
- Poland
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Medical University of Silesia
Cardiovascular Diseases, Diabetes Mellitus, Type 2
The Japan Diabetes Optimal Integrated Treatment Study for 3 Major Risk Factors of Cardiovascular Diseases
(Intervention study) The objective of the study is to confirm the superiority of the intensive therapy to the conventional therapy concerning the prevention of the incidence or exacerbation of vascular complications caused by…
- Trial name
- J-DOIT3 (NCT00300976)
- Testing
- Lifestyle consultation: weight control, diet, exercise
- Where
- Japan
- Volunteers
- 2,542 people
- Sponsor
- Japan Foundation for the Promotion of International Medical Research Cooperation
Ferritin, Insulin Sensitivity
Blood Donation Could Improve Insulin Sensitivity
Studies in the literature suggest that people with obesity have an excess of stored iron. There is possibly an inverse relationship between ferritin levels and the actions of insulin on glycemic control.
- Conditions
- Ferritin, Insulin Sensitivity, Blood Donation
- Trial name
- GLUCFER (NCT05791968)
- Testing
- Whole blood standard donation
- Where
- Spain
- Volunteers
- 89 people
- Sponsor
- University of Castilla-La Mancha
Diabetes
Clinical Test of Blood Glucose Test Strips
Blood glucose test strips are tested with the test meters to test the accuracy of the blood pressure monitoring function.
- Trial name
- NCT00976924
- Testing
- blood glucose monitor
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Andon Medical Co.,Ltd
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