Clinical trials: Blood Loss, Postoperative
Blood Loss, Surgical, Blood Loss, Postoperative
Comparative Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate
Comparative Study Between Oxytocin Versus Tranexamic Acid and Ethamsylate, Pre-operative Administration.
- Trial name
- NCT04656067
- Testing
- Oxytocin ,Tranexamic acid and Ethamsylate
- Where
- Egypt
- Volunteers
- 230 people, healthy volunteers welcome
- Sponsor
- Egymedicalpedia
Stroke, Ischemic, Pain, Postoperative
A Multiple Ascending Dose Study of Safety and Pharmacokinetics of NP10679 in Normal Healthy Volunteers
This multiple ascending dose study assesses the safety, tolerability and pharmacokinetics of NP10679 when delivered intravenously in escalating dose levels in comparison to placebo.
- Conditions
- Stroke, Ischemic, Pain, Postoperative, Substance Abuse, Subarachnoid Hemorrhage
- Trial name
- NCT04007263
- Testing
- NP10679
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Neurop Inc.
Misoprostol Allergy
Pre Versus Post-operative Misoprostol in Reducing Blood Loss After Cesarean Section
Cesarean section is the most common performed major surgical interventions among women all over the world.Cesarean section has many serious complications, including primary postpartum hemorrhage (PPH).
- Trial name
- NCT05928871
- Testing
- Misoprostol 200mcg Tab, Misoprostol Pill
- Where
- Egypt
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Cairo University
Liposuction, Bruising
Bridging the Healing Gap: A Single-Blind Clinical Trial Assessing the Efficacy of Carboxy-gel in Reducing Bruising and Pain Post-Liposuction
The goal of this clinical trial is to evaluate if CO2 Lift reduces bruising and pain after Liposuction. The study also aims to explore changes in patient satisfaction.
- Conditions
- Liposuction, Bruising, Inflammation, Pain, Postoperative
- Trial name
- CO2L001 (NCT06791577)
- Testing
- Carboxytherapy
- Where
- 3 sites in Brazil, Colombia and 1 more
- Volunteers
- 72 people, healthy volunteers welcome
- Sponsor
- Total Definer Research Group
Thrombosis
Efficacy and Safety of Short-term Postoperative Anticoagulant Therapy to Prevente Thrombosis in Arterovenous Fistula
Many guidelines at home and abroad advocate that arteriovenous fistula should be the first choice of permanent vascular access, but it is easy to form thrombus in a short time after arteriovenous fistula molding, resulting in…
- Trial name
- EASOAT (NCT04164693)
- Testing
- Low molecular weight heparin, non anticoagulant therapy group
- Where
- China
- Volunteers
- 287 people, healthy volunteers welcome
- Sponsor
- First Affiliated Hospital of Chongqing Medical University
Post Operative Pain, Post-Op Hemorrhage
Admission of the Patient to the Clinic After Surgery
Aim:This research was designed as a randomized controlled study to examine the effect of the game-based virtual reality learning method on the patient's post-operative admission to the clinic on the learning outcomes of the…
- Conditions
- Post Operative Pain, Post-Op Hemorrhage, Postoperative Hypothermia, Nurse's Role
- Trial name
- NCT05469399
- Testing
- Experimental Group, Control Group
- Volunteers
- 82 people, healthy volunteers welcome
- Sponsor
- Gazi University
Shoulder Arthroscopy, Operative Bleeding
The Effect of Tranexamic Acid (TXA) on Visualization During Shoulder Arthroscopy
Tranexamic acid has seen an increase in use over the past decade in hip and knee arthroplasty as well as spine surgery with more recent use seen in total shoulder arthroplasty (TSA).
- Conditions
- Shoulder Arthroscopy, Operative Bleeding, Postoperative Pain
- Trial name
- NCT04610164
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Rothman Institute Orthopaedics
Infection, Bleeding
Effects of Microcrystalline Titanium Dioxide With Covalently Linked Monovalent Silver Ions on Complications After Total Hysterectomy
Total hysterectomy is one of the most performed surgical procedures in the world and it is associated with post-operative complications.
- Conditions
- Infection, Bleeding, Complication, Postoperative
- Trial name
- ISTIAB-1 (NCT03789799)
- Testing
- TIAB: microcrystalline titanium dioxide with covalently linked monovalent silver ions
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Università degli Studi dell'Insubria
Surgery, Postoperative Blood Loss
Tranexamic Acid in Rhinoplasty: Perioperative Bleeding, Edema and Ecchymosis
This study will be a prospective randomized study to evaluate the effect of tranexamic acid (TXA) use on intraoperative and postoperative outcomes among patients undergoing rhinoplasty by two Facial Plastic surgeons at…
- Trial name
- NCT05774717
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Vanderbilt University Medical Center
Tooth Extraction, Postoperative Hemorrhage
Post-extraction Bleeding in Older Adults on Uninterrupted Antiplatelet Therapy
This prospective, assessor-blinded, controlled observational study compares bleeding after simple tooth extraction between adults aged 40 years or older who continue their antiplatelet therapy (aspirin, clopidogrel or dual…
- Conditions
- Tooth Extraction, Postoperative Hemorrhage, Platelet Aggregation Inhibitors
- Trial name
- NCT07913035
- Testing
- Antiplatelet therapy (uninterrupted), Simple tooth extraction with stepwise local haemostatic protocol
- Where
- Vietnam
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- University of Medicine and Pharmacy at Ho Chi Minh City
Osteoarthritis, Knee
Postoperative Drainage in Total Knee Arthroplasty in the Presence of Tranexamic Acid
The investigator's aim with this study is to address, with the new paradigm of tranexamic acid, the role of wound drainage following total knee arthroplasty in blood loss, blood transfusion requirements and functional recovery
- Trial name
- NCT03915756
- Testing
- Drainage of surgical wound
- Where
- Portugal
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Hospital Beatriz Ângelo
Osteoarthritis
Study Comparing Peri-articular Injection of Bupivacaine With and Without Epinephrine
This study involves research. The purpose of this research is to formally investigate the hemostatic efficacy of epinephrine to minimize blood loss after total joint arthroplasty.
- Trial name
- NCT00737139
- Testing
- Peri-articular injection of marcaine/epinephrine, Peri-articular injection of marcaine alone
- Where
- United States
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Rush University Medical Center
Tourniquets, Knee Arthroplasty, Total
Tourniquet Pressure in Primary Total Knee Arthroplasty
This proposed novel randomized control trial (RCT) seeks to address this gap in TKA protocol by gaining a better understanding of the relationship between tourniquet pressure and time, and intraoperative performance and…
- Conditions
- Tourniquets, Knee Arthroplasty, Total, Knee Replacement, Total
- Trial name
- NCT02830087
- Testing
- Tourniquet Cuff Pressure
- Where
- 2 sites in United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Hemorrhage, Pain
Effect of Tonsillar Pillar Closure on Postoperative Pain and Bleeding Risk After Tonsillectomy
The purpose of this study is to determine if closing the tonsil fossa after tonsillectomy leads to less pain and bleeding risk than leaving it open to heal by secondary intention.
- Trial name
- NCT00394849
- Testing
- suture one tonsillar fossa
- Where
- United States
- Volunteers
- 763 people, healthy volunteers welcome
- Sponsor
- Indiana University
Chronic Subdural Hematoma
Postoperative Balloninflation After Evacuation of cSDH
In this prospective, randomized, multicenter trial shall patients with chronic subdural hematoma (cSDH) recruited, who were surgically treated.
- Trial name
- BANISH (NCT04060186)
- Testing
- Balloninflation
- Where
- Germany
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Johann Wolfgang Goethe University Hospital
Infection, Bleeding
Effects of Microcrystalline Titanium Dioxide With Covalently Linked Monovalent Silver Ions on Complications After Total Hysterectomy ( ISTIAB-0)
Total hysterectomy is one of the most performed surgical procedures in the world and it is associated with post-operative complications.
- Conditions
- Infection, Bleeding, Complication, Postoperative
- Trial name
- ISTIAB-0 (NCT03791294)
- Testing
- TIAB: microcrystalline titanium dioxide with covalently linked monovalent silver ions
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Università degli Studi dell'Insubria
Cardiac Surgery, Bone Wax, NU-KNIT, Median Sternotomy, Deep Sternal Wound Infection, Surgical Site Infection
Surgicel NU-KNIT Vs Bone Wax on Median Sternotomy
Bone wax is traditionally used as part of surgical procedures to prevent bleeding from exposed spongy bone. It is an effective hemostatic device which creates a physical barrier.
- Trial name
- NBCS (NCT06869772)
- Testing
- Closure of sternotomy
- Where
- Qatar
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hamad Medical Corporation
Pain, Postoperative, Healing Wound
Evaluation of the Effects of Medicaments Used After Free Gingival Graft on Postoperative Complications.
In our study, three different medicaments were evaluated in terms of postoperative complications after free gingival grafting (FGG).
- Conditions
- Pain, Postoperative, Healing Wound, Hemorrhage, Analgesia
- Trial name
- NCT05386667
- Testing
- Majezik %0.25 oral spray, Aftamed oral spray, Crystalin oral spray
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Postpartum Hemorrhage
Comparison Between Rectal & Sublingual Misoprostol Before Caesarian Section To Reduce Intra & Post-Operative Blood Loss
The aim of the work is to evaluate \& compare the effectiveness of rectally administered PGE1 synthetic analogue (misoprostol) 400 microgram versus sublingually administered misoprostol before caesarean section to decrease blood…
- Trial name
- NCT02083107
- Testing
- Misoprostol
- Where
- Egypt
- Volunteers
- 636 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Postoperative Hemorrhage
Efficacy of Intra-auricular Tranexamic Acid in Total Knee Arthroplasty
Tranexamic acid an antifibrinolytic that develops its anti-haemorrhagic action by inhibiting fibrinolytic activities of plasmin and many studies confirms its effectiveness in decreasing blood loss.
- Trial name
- NCT04085575
- Testing
- Acide Tranexamique
- Where
- France
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier de Montauban