Clinical trials: Bone Age
Age-related Degenerated Disease
Relationships Between Quality of Ageing and Age-related Degenerated Disease (Compalimage)
This project aims to assess the impact of chronic micro-inflammation on age-related loss of muscle (sarcopenia) and bone (osteopenia).
- Trial name
- Compalimage (NCT00862615)
- Testing
- Measurement of muscle protein synthesis using stable isotopes and muscle biopsies.
- Where
- France
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University Hospital, Clermont-Ferrand
Spine Disease, Gait
Gait Spine Functional Evaluation Protocol
The goal of this clinical trial is to develop and validate of a new protocol for multifactorial functional assessment of the kinematics of spinal and total body movements during walking by means of the optoelectronic motion…
- Trial name
- NCT06400680
- Testing
- Spine Kinematic Assessment with Optoelectronic system
- Where
- Italy
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- IRCCS Eugenio Medea
Osteoporosis, Age-Related
Bone Mineral Density and Bone Metabolism in Older Women
The objective of this study is to assess the impact of different exercise interventions on bone mineral density (BMD) in older women. It will also evaluate the safety and compliance of these interventions.
- Trial name
- BMD (NCT06529172)
- Testing
- Resistance training, Yijinjing, Baduanjing
- Where
- China
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Cheng Liang
Falls, Osteopenia
Effect of a Wii Fit Intervention on Components of Fall Risk in Middle-aged Women
Losses of muscular fitness/balance are common occurrences with aging that can lead to an increased fall-risk. The accelerated bone loss that may accompany menopause makes some women even more "at-risk" for serious consequences…
- Trial name
- NCT01897467
- Testing
- Wii Fit, Wait-List Control
- Where
- United States
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Arizona State University
Cognition, Inflammation Biomarkers
Dietary Supplements and Middle Aged Women (Collagen & Omega)
This study will examine the effects of combining different types of dietary supplements on various aspects of health and wellbeing in middle aged women.
- Conditions
- Cognition, Inflammation Biomarkers, Bone Metabolism Biomarkers, Fatigue Symptom
- Trial name
- NCT07740967
- Testing
- Collagen peptides and omega-3
- Where
- United Kingdom
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Atrophy
Effect of Whole Body Vibration on Bone and Fall Related Parameters
The effect of whole body vibration (WBV) on bone strength and fall frequency in older adults is still vague. Although there is some evidence that WBV may impact Bone Mineral Density in very frail elderly, there is a lack of data…
- Trial name
- NCT00292916
- Testing
- whole body vibration, resistance exercise, "wellness"
- Where
- Germany
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- University of Erlangen-Nürnberg Medical School
Complement Mediated Diseases
First-In-Human Clinical Study of the C3 Complement Inhibitor AMY- 101 in Healthy Male Volunteers
Safety, tolerability, pharmacokinetics (PK) and pharmacodynamics (PD) of a Single Ascending Dose (SAD) and a Multiple Dose (MD) of the complement inhibitor AMY-101.
- Trial name
- NCT03316521
- Testing
- AMY-101
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Amyndas Pharmaceuticals S.A.
Frail Elderly Syndrome
HOPE (Healthy Older People Everyday) To Age in Place
Certain clinical syndromes eg frailty, sarcopenia, dementia, depression, cognitive impairment, vision impairment, falls in older adults carry an increased risk for poor health outcomes and if identified early, can be prevented…
- Trial name
- NCT03797352
- Testing
- Multicomponent exercise
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- National University Hospital, Singapore
Bone and Bones, Osteoporosis Risk
Milk Protein and Bone Health in Postmenopausal Women
The process of bone remodeling exhibits pronounced diurnal pattern that is important for bone health. A balanced rate of bone resorption is required to maintain bone health, a balance that can be disturbed during the life-cycle…
- Conditions
- Bone and Bones, Osteoporosis Risk, Osteoporosis, Postmenopausal
- Trial name
- OSTEOMILK (NCT03701113)
- Testing
- Milk-based protein matrix (MBPM), Habitual dietary behaviour
- Where
- Ireland
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- University of Limerick
Immunocompromised, Transplanted
Seasonal Flu Vaccine in Adult Transplant Recipients
The trial investigates the efficacy of adjuvanted seasonal influenza including H1N1 Fluad (R) in immunocompromised adults who have undergone solid organ or bone marrow transplantation.
- Trial name
- Fluad Tx (NCT01258023)
- Testing
- Fluad 1x
- Where
- Germany
- Volunteers
- 122 people, healthy volunteers welcome
- Sponsor
- HepNet Study House, German Liverfoundation
Osteoporosis, Health Literacy Level
Health Literacy and Osteoporosis Awareness
Osteoporosis (OP) is defined as a progressive metabolic bone disease characterized by low bone mass and deterioration of the microarchitecture of bone tissue, resulting in increased bone fragility and a higher risk of fractures.
- Conditions
- Osteoporosis, Health Literacy Level, Awareness and Knowledge Level
- Trial name
- NCT07419451
- Testing
- Patients will only fill out a questionnaire.
- Where
- Turkey (Türkiye)
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- Bandırma Onyedi Eylül University
Osteoporosis, Bone Loss, Age Related
Osteoporosis Choice Decision Aid for Use of Bisphosphonates in Postmenopausal Women
To develop a decision aid to support the decision to use (or not use) bisphosphonates in postmenopausal women at risk for osteoporotic fractures, and to assess the impact of the decision aid on start and six month adherence to…
- Conditions
- Osteoporosis, Bone Loss, Age Related, Postmenopausal Bone Loss, Postmenopausal Osteoporosis
- Trial name
- NCT00578981
- Testing
- Osteoporosis Choice Decision Aid
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Control, Population
Bone Age Determined by Ultrasound (BAUS) in Brazilian Control Children
Aiming to validate the use of bone age determined by ultrasound (BAUS) in Brazilian children, normal control students will be studied.
- Trial name
- NCT03190109
- Where
- Brazil
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Faculdade de Ciências Médicas da Santa Casa de São Paulo
Bone Density
Reference Curves for Bone Mineral Density and Body Composition in Women Aged 20-89
Up-to-date normalcy curves for bone mineral density and body composition (fat and lean mass), are currently lacking. DMS IMAGING is therefore financing the MONIKA study, with Nîmes University Hospital as sponsor.
- Trial name
- MONIKA (NCT06983587)
- Testing
- Bone densitometry scan
- Where
- 2 sites in France
- Volunteers
- 425 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Osteoporosis Risk
Investigation of the Effects of Physical Activity in Women at Risk of Osteoporosis
The goal of this clinical trial is to investigate the effects of the increase in the physical activity level of women at risk for osteoporosis in the post-menopausal period on the physical fitness, functional fitness age and…
- Trial name
- NCT06081764
- Testing
- Exercise
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Healthy, Osteopenia
Clinical Study to Predict the Risk of Bone Fractures With the POROUS Ultrasound Device
Osteoporosis is a widespread medical condition among older people. It causes the bones to weaken and become more likely to break.
- Conditions
- Healthy, Osteopenia, Osteoporosis
- Trial name
- POROUS-preFX (NCT06567054)
- Testing
- Measurements with the POROUS R3C ultrasound device at the midshaft tibia, DXA measurement of the hip and lumbar spine, DXA-based Vertebral Fracture Assessment (VFA)
- Where
- 6 sites in Austria, Germany and 1 more
- Volunteers
- 1,600 people, healthy volunteers welcome
- Sponsor
- POROUS GmbH
Overweight and Obesity, Body Composition
Aerobic Exercise and Body Composition in Overweight and Obese Boys.
Overweight and obesity are unhealthy fat accumulations. children aged 2-18 are deemed overweight if their body mass index (BMI)/Age is ≥ 85th - <95th percentile and obese if >95th percentile.
- Conditions
- Overweight and Obesity, Body Composition, Body Fat, Lean Body Mass
- Trial name
- NCT07586579
- Testing
- aerobic exercise
- Where
- Indonesia
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Universitas Sriwijaya
Bone Loss, Age Realted, Post Menopausal
Flaxseed Consumption and Bone Metabolism in Postmenopausal Women.
This proposed randomized double blinded, placebo-controlled, parallel trial; with two arms, in females aged 50-70 years, volunteers will be postmenopausal with a BMI between 25-35 kg/m2.
- Trial name
- FLAX (NCT03036722)
- Testing
- Flaxseed
- Where
- United Kingdom
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Reading
Age Related Osteoporosis, Fall
Effects of FRAX+SARC-F Pre-screening on Preventing Fragility Fracture and Fall in Community-dwelling Older Adults
Hip fragility fractures are a major threat to functional independence in older adults locally and globally. In Hong Kong, the prevalence of osteoporosis and osteopenia in people aged >50 years were reported to be as high as 37%…
- Trial name
- NCT04709393
- Testing
- FRAX+SARC-F questionnaire pre-screening
- Where
- Hong Kong
- Volunteers
- 2,956 people, healthy volunteers welcome
- Sponsor
- Chinese University of Hong Kong
Osteoporosis, Accidental Falls
Geriatric Health Exam Osteoporosis Screening
BACKGROUND: The World Health Organization Fracture Risk Assessment Tool (WHO FRAX®) Taiwanese calculator is freely available on line to help osteoporosis management.
- Conditions
- Osteoporosis, Accidental Falls, Fracture
- Trial name
- NCT01934387
- Where
- Taiwan
- Volunteers
- 1,319 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital