Clinical trials: Bone Loss, Alveolar
Vertical Alveolar Bone Loss
Initial Clinical and CBCT Outcomes of Enamel Matrix Derivative-Based Regenerative Therapy in Vertical Bone Defects
Study of the effectiveness of the application of regenerative therapy with autogenous, platelet-rich plasma in vertical defects Investigation of the effectiveness of the application of regenerative therapy with enamel matrix…
- Trial name
- NCT06639555
- Testing
- PRP( platelet rich plasma), EMD (Enamel Matrix Derivative), Guided Tissue Regeneration (barrier membrane)
- Where
- Bulgaria
- Volunteers
- 48 people
- Sponsor
- Tsvetalina Gerova-Vatsova
Vertical Alveolar Bone Loss
Clinical Evaluation of RTX Locator Attachments for Implant-supported Mandibular Complete Overdenture
This study was conducted to clinically and radiographically evaluate locator RTx attachments for two implant-supported mandibular overdenture using two loading protocols
- Trial name
- NCT05290376
- Testing
- surgical placement of long dental implants, overdenture supported by RTX attachment system
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Tooth Avulsion, Tooth Crown Fracture
Therapeutic Wavelength Nanotechnology Devices in Alveolar Preservation
After tooth extraction, a progressive alveolar bone resorption is observed. Alveolar ridge preservation consists of placing a biomaterial within the extraction socket and covering it with a membrane.
- Trial name
- APnanotecnolog (NCT07371130)
- Testing
- Socket Preservation
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Bari Aldo Moro
Bone Loss in Jaw, Edentulous Alveolar Ridge
BMAC on PCL Scaffold for Ridge Augmentation
BMAC is used on 3D printed PCL scaffold for horizontal ridge augmentation in aesthetic zone , BMAC contains MSCs which can differentiate in osteogenic medium into osteoblasts which can lay down bone
- Trial name
- NCT05241548
- Testing
- BMAC on PCL Scaffold
- Where
- Egypt
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- Cairo University
Primary Stability of the Implants, Marginal Bone Loss
Inferior Alveolar Nerve Lateralization With Simultaneous Implant Placement Versus the Use of Short Dental Implants
Assess the long term stability of short dental implants in comparison to standard implants inserted simultaneously with inferior alveolar nerve lateralization.
- Trial name
- NCT03661658
- Testing
- Using short dental implant, Inferior alveolar nerve lateralization with simultaneous implant placement
- Where
- Egypt
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Cairo University
Tooth Loss, Partial-edentulism
Retrospective Evaluation of a Novel Biomimetic Synthetic Bone Substitute (Creos® Syntogain)
Guided bone regeneration (GBR) is a commonly performed technique, using autogenous grafts, allografts, xenografts, or synthetic bone grafts (SBG).
- Conditions
- Tooth Loss, Partial-edentulism, Tooth Fracture, Edentulous Alveolar Ridge
- Trial name
- NCT06473545
- Where
- 2 sites in Spain
- Volunteers
- 173 people
- Sponsor
- International dentistry Research Group
Peridontal Disease, Rheumatic Arthritis
Nonsurgical Periodontal Treatment Combined With Anti-TNF-α in Patients With Rheumatoid Arthritis and Periodontitis
Periodontitis is a multifactorial disease of the periodontium that can lead to destruction of the alveolar bone and supporting connective tissue and subsequent tooth loss.
- Trial name
- NCT06818045
- Testing
- Non Surgical Periodontal Treatment, Periodontal measurements will be performed, biochemical measurements
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people
- Sponsor
- Hatice Yemenoğlu
Periodontitis
Regeneration of Human Intrabony Defects With rhFGF-2/HA
BACKGROUND: Periodontal disease is an infection that results in progressive loss of dental support, which may lead to tooth loss..
- Trial name
- NCT02337166
- Testing
- a gel containing 4mg/ml rhFGF-2 in sodium hyaluronate, Periodontal flap surgery
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universidade Federal Fluminense
Periodontal Diseases, Periodontal Pocket
Comparison of Gingival Flap Procedure Using Conventional Surgical Loupes vs. Videoscope for Visualization
This study is being performed to compare different methods of visualization during routine gum surgery. The gum surgery is standard of care.
- Conditions
- Periodontal Diseases, Periodontal Pocket, Periodontitis, Periodontal Inflammation
- Trial name
- NCT05932017
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Texas A&M University
Alveolar Bone Resorption, Alveolar Ridge Trauma
Vertical Ridge Augmentation Strategies
Guided Bone Regeneration (GBR) is an invaluable and beneficial surgical technique adopted when there is the need to augment an alveolar atrophy.
- Conditions
- Alveolar Bone Resorption, Alveolar Ridge Trauma, Alveolar Bone Loss, Complication of Surgical Procedure
- Trial name
- VARGAS (NCT06242782)
- Testing
- VRA + d-PTFE membrane, VRA + e-PTFE membrane, VRA + customised Ti-mesh
- Volunteers
- 148 people
- Sponsor
- University College, London
Bone Atrophy, Alveolar
All-on-Four Implants With Ultrasonic
The objective of this observational study is the radiographic evaluation of marginal bone remodeling after surgical implant insertion in an immediate loading all-on-four technique with trans-sinusal titanium implants, correlating…
- Trial name
- Nobelsinus (NCT03357692)
- Testing
- all on four implant rehabilitation
- Where
- Italy
- Volunteers
- healthy volunteers welcome
- Sponsor
- International Piezosurgery Academy
Healing Wound, Alveolar; Wound
Ultrasound for Socket Healing Evaluation
The design is a single blinded, dual comparative study of ultrasound versus micro-CT/LASCA in one study group. Up to a total of 140 subjects registered will be recruited.
- Conditions
- Healing Wound, Alveolar; Wound, Alveolar Bone Loss, Image
- Trial name
- NCT06017193
- Where
- United States
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- University of Michigan
Periodontal Bone Loss
The Use of Chlorhexidine Gel Following EDTA Root Surface Etching as an Adjunctive to Open Flap Debridement in Treating Intra-Bony Defects
SUMMARY Chronic periodontitis is regarded as an inflammatory disease that affects the supporting tissues of teeth which could lead to bone destruction.
- Trial name
- NCT05170932
- Testing
- CHX gel 2 % + 24% EDTA
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Periodontitis, Dental Caries
Using Combination of Synthetic Bone Substitutes During Extractions
The study was designed to assess the effectiveness of conservation ridge preservation (horizontal and vertical dimension) after tooth extraction with and without combination of bone substitutes based on synthetic (calcium sulfate…
- Conditions
- Periodontitis, Dental Caries, Alveolar Bone Losses
- Trial name
- NCT01503593
- Testing
- Calcium Phosphate, Calcium Sulphate
- Volunteers
- 40 people
- Sponsor
- Rambam Health Care Campus
Alveolar Bone Loss
Evaluation of Short Implants' Success for Teeth Replacement in Atrophic Posterior Mandibular Ridge
The aim of this study was to evaluate clinically and radiographically the splinted short implants' and single short implants' stability and bone condition before and after loading, in atrophic posterior mandibular alveolar ridges.
- Trial name
- NCT04414709
- Testing
- Double short implant, Single short implant
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- Alexandria University
Alveolar Bone Loss
Histological Outcome of the Use of Different Biomaterials for Fresh Socket Regeneration. A Split-mouth Design
Purpose: The aim of this study was to analyze the quality of bone regeneration in fresh sockets using four different materials and at different times points.
- Trial name
- NCT05183386
- Testing
- dental socket regeneration
- Volunteers
- 30 people
- Sponsor
- University of Salamanca
Edentulous Jaw, Bone Loss, Alveolar
Effects of Different Centrifuged Platelet Concentrates on Bone Remodelling Around Dental Implants
Platelet concentrates obtained from blood have been used as regenerative biomaterials in periodontal surgery. Along with the migration and proliferation of osteogenic cells, platelets accelerate bone regeneration by increasing…
- Conditions
- Edentulous Jaw, Bone Loss, Alveolar, Resorption, Bone
- Trial name
- NCT04851002
- Testing
- Application of concentrated growth factor with dental implants, Application of advanced platelet rich fibrin with dental implants, Control side of concentrated growth factor study group
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Muhammet Atilgan
Bone Loss, Alveolar, Dental Implant Failed
Clinical, Radiological and Microbiological Outcomes of Implants With Two Different Connection Configurations, a Split-mouth RCT.
This study designed as a randomized controlled split-mouth trial will be conducted at the Dental Clinic of the University of Valencia.
- Trial name
- NCT03528330
- Testing
- Rehabilitation with dental implant with internal hexagon connection, Rehabilitation with dental implant with conical connection
- Where
- Spain
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Valencia
Horizontal Alveolar Bone Loss
Horizontal Ridge Augmentation Using Polyvinylidene Fluoride Versus Titanium Mesh Membranes
This study aims to evaluate the effectiveness of a new PVDF non-resorbable membrane versus Titanium Mesh in the treatment of horizontal ridge defects prepared for implant placement
- Trial name
- PVDF + HRA (NCT07095530)
- Testing
- titanium membrane
- Where
- Egypt
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Minia University
Alveolar Ridge Preservation Post-Extraction Bone Healing Dental Implant Site Development Tooth Loss
Early Dental Implant Installation in Regeneration Sites: a Prof of Concept Prospective Case Study
This study will evaluate bone healing after tooth extraction and alveolar ridge preservation, a common procedure used to maintain the bone volume needed for future dental implant placement.
- Trial name
- NCT07766057
- Testing
- Alveolar Ridge preservation and early implant placement
- Where
- Chile
- Volunteers
- 10 people
- Sponsor
- Franco Cavalla