Clinical trials: Bone Loss
Stroke
Effect of Zoledronic Acid on Prevention of Bone Loss in Acute Phase First-ever Stroke Patients
In order to reduce the incidence of fractures due to osteopenia, osteoporosis, and bone mineral density in first stroke patients, the purpose of this study was to determine whether it is meaningful to administer zoledronic acid…
- Trial name
- NCT04652128
- Testing
- Zoledronic acid
- Where
- South Korea
- Volunteers
- 56 people
- Sponsor
- Yonsei University
Trauma Injury, Trauma
The Role of Brain-Bone Marrow-Gut Interaction Following Major Trauma
Traumatic injury followed by critical illness provokes pathophysiologic changes in the bone marrow and the gut that contribute to persistent anemia and changes in the microbiome which significantly impact long-term recovery.
- Conditions
- Trauma Injury, Trauma, Critical Illness, Microbiome
- Trial name
- NCT06606119
- Testing
- Data and tissue collection
- Where
- 3 sites in United States
- Volunteers
- 275 people
- Sponsor
- University of Florida
Osteopenia or Osteoporosis
Effect of Consumption of Supplements and Enriched Olive Paste on Bone Metabolism Indices
It was a prospective randomized controlled trial. A sample of 115 apparently healthy post-menopausal women(45 -75 years of age) randomized into four groups and received supplements of Ca, Vitamin D and Mg with or without enriched…
- Trial name
- Osteoporosis (NCT06135831)
- Testing
- Functional olive paste, Calciovitmag (CDCaMg), Phosporovitmag (PDCaMg)
- Where
- Greece
- Volunteers
- 115 people
- Sponsor
- University of the Aegean
Bone Diseases, Metabolic, Diabetes Mellitus, Type 2
A Clinical Trial to Evaluate the Bone Metabolism and the Blood Sugar of Evogliptin and Dapagliflozin
This multi-center, randomized and exploratory clinical trial is designed to evaluate the effect of bone metabolism and blood sugar of evogliptin and dapagliflozin in the menopause female patients with osteopenia and type 2…
- Trial name
- EVOMETA (NCT04706637)
- Testing
- Evogliptin, Dapagliflozin
- Where
- 7 sites in South Korea
- Volunteers
- 120 people
- Sponsor
- Kyung Hee University Hospital at Gangdong
Hearing Loss, Conductive, Hearing Loss, Unilateral
Adhear Bone Conduction System
The purpose of this research study is to learn about the hearing outcomes of adult and pediatric patients who are treated with or are candidates for bone conductive devices (also termed "BAHA").
- Trial name
- NCT03533686
- Testing
- Adhear Bone Conduction System, Bone anchored hearing aid (BAHA)
- Where
- United States
- Volunteers
- 66 people
- Sponsor
- University of Miami
Tooth Loss
Implant Survival After Insertion of Bone Level Tapered (BLT) Implant Ø 2.9 mm in the Clinical Practice Setting
The Straumann Bone Level Tapered (BLT) implant Ø 2.9 mm implant was developed to allow treatment of patients with single tooth gaps of small dimensions in the lateral and central incisor positions in the mandible and in the…
- Trial name
- NCT02699866
- Testing
- BLT Implant Ø 2.9 mm
- Where
- 5 sites in Germany
- Volunteers
- 46 people
- Sponsor
- Institut Straumann AG
COPD, Osteoporosis
Osteoporosis and Chronic Obstructive Pulmonary Disease (COPD)
The goals of the trial are: To determine the prevalence of osteoporosis in subgroups of COPD patients. To look for risk factors of osteoporosis in COPD patients.
- Conditions
- COPD, Osteoporosis, Osteopenia
- Trial name
- NCT00231127
- Where
- Netherlands
- Volunteers
- 250 people
- Sponsor
- Catharina Ziekenhuis Eindhoven
Hip Fracture, Blood Loss
Prevention of Postoperative Bleeding in Subcapital Femoral Fractures
The main hypothesis of this clinical trial is that the use of intra-articular tranexamic acid and the fibrin glue plus usual hemostasis will reduce at least a 25% the postoperative blood loss with respect to usual hemostasis in…
- Trial name
- TRANEXFER (NCT02150720)
- Testing
- Tranexamic Acid, Fibrin glue, Electrocauterization
- Where
- 6 sites in Spain
- Volunteers
- 161 people
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Psoriatic Arthritis
Effect of Exercise and Diet on Psoriatic Arthritis
Psoriatic arthritis (PsA) is a particular pattern of inflammatory arthritis often seen in association with psoriasis. PsA patients have a higher prevalence of comorbidities including obesity, metabolic syndrome, depression and…
- Trial name
- NCT02188641
- Testing
- Diet, Exercise, Diet and Exercise
- Where
- Egypt
- Volunteers
- 55 people
- Sponsor
- University of Alexandria
Bone Loss, Alveolar
Outcomes of Ridge Splitting Versus Sausage Technique
The current study aims to increase the width of the alveolar bone in defective mandibular ridge with simultaneous implant placement and enhance the implant stability
- Trial name
- NCT07664605
- Testing
- Ridge split
- Where
- Egypt
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Beni-Suef University
Osteoporosis, Osteopenia
Dried Plums Prevent Inflammation And Improve Bone Health in Osteopenic Men
The goals of this study are 1) to investigate the extent to which dried plum improves bone health by measuring bone density (a measure of bone strength) of whole body, hip, and forearm, indicators of bone formation and bone…
- Trial name
- NCT03408119
- Testing
- Dried Plum, 800 IU vitamin D and 450mg elemental calcium
- Where
- United States
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Florida State University
Diabetes Mellitus, Type 2, Bone Loss
Effect of Vitamins D3 and K2 in uOc and Insulin Serum Levels in Patients With Diabetes Mellitus
Introduction: Patients with DM2 have chronic hyperglycemia derived from a decrease in insulin sensitivity, cause of comorbidities such as bone demineralization, decreasing quality of life and increasing mortality.
- Conditions
- Diabetes Mellitus, Type 2, Bone Loss, Insulin Resistance
- Trial name
- NCT04041492
- Testing
- Supplementation with Vitamin D3 y K2
- Where
- Mexico
- Volunteers
- 100 people
- Sponsor
- University of Guadalajara
Perimenopausal Bone Loss
Natto Supplementation to Prevent Loss of Bone Mass in Women Immediately After Menopause
Study Objective: To determine whether Natto supplementation in women immediately after menopause might prevent severe bone loss Study population: Women 50 - 60 years, 1-5 years after menopause Study Design: Double-blind…
- Trial name
- NCT00290212
- Testing
- Natto capsules (food suppl.) cont. 360 microg. vit K2/day
- Where
- 2 sites in Norway
- Volunteers
- 304 people, healthy volunteers welcome
- Sponsor
- University Hospital of North Norway
Breast Cancer, Osteoporosis
Zoledronate, Calcium, and Vitamin D in Preventing Bone Loss in Women Receiving Adjuvant Chemotherapy for Breast Cancer
RATIONALE: Zoledronate plus calcium and vitamin D may prevent bone loss in patients receiving adjuvant chemotherapy for breast cancer. It is not yet known which regimen is more effective in preventing bone loss.
- Trial name
- NCT00022087
- Testing
- calcium salts, cholecalciferol, zoledronic acid
- Where
- 107 sites in United States
- Volunteers
- 439 people
- Sponsor
- Alliance for Clinical Trials in Oncology
Inclined Atrophy of the Distal Mandible, Socket Like Atrophy of the Aesthetic Zone
PEERS Multicenter Osseospeed TM TX Profile Implant: German Astra Soft Tissue (GAST) Maintenance Study
The open, prospective, non-controlled observational study is designed to provide information on the short-, medium- and long-term clinical performance of the Astra Tech OsseospeedTM implant surface in combination with a special…
- Trial name
- GAST (NCT01400321)
- Where
- 28 sites in Germany
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Johannes Gutenberg University Mainz
Femoral Fractures
Study Of Tranexamic Acid For The Reduction Of Blood Loss In Patients Undergoing Surgery For Long Bone Fracture
Tranexamic acid has been shown to reduce postoperative blood losses and transfusion requirements in a number of types of surgery.
- Trial name
- NCT00824564
- Testing
- Tranexamic Acid plus standard of care, Standard of care
- Where
- India
- Volunteers
- 82 people
- Sponsor
- Pfizer
Alveolar Bone Loss, Maxillary Sinus Bone Loss
Anti-HLA Antibodies After Bone Regeneration Surgery
This study evaluates the occurrence of anti-human leukocyte antigen (anti-HLA) antibodies following bone regeneration procedures performed prior to dental implant therapy.
- Trial name
- Anti-HLA Bone (NCT07474857)
- Testing
- Xenogeneic Bone Graft, Allogeneic Bone Graft, Low-Level Laser Therapy
- Where
- Poland
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Medical Innovation Center Wroclaw
TIBIA PSEUDOARTHROSES
Segment Transport Versus Acute Shortening In The Treatment of Tibial Pseudarthroses With Bone Loss
In this study the investigators are presenting the advantages as well as the disadvantages of ACUTE SHORTENING AND RELENGTHENINIG VS SEGMENT TRANSPORT methods.
- Trial name
- NCT01246934
- Testing
- ASR METHOD
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Bezmialem Vakif University
Dental Implant, Bone Loss
Ridge Augmentation Using Allograft Particles Hydrated With or Without Recombinant Human Platelet-Derived Growth Factor
This study will compare two techniques to achieve increase in ridge dimensions as a preparation for dental implants using a resorbable barrier membrane and bone particulate allogenic graft hydrated with saline or a growth factor…
- Trial name
- NCT04954664
- Testing
- Allograft particles hydrated with rhPDGF, Allograft particles hydrated in a conventional way with saline.
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Conductive Hearing Loss, Mixed Hearing Loss
Clinical Survey of Oticon Medical Ponto Implants and a Surgical Technique With Tissue Preservation
A bone anchored hearing system is used to improve hearing for patients with e.g. conductive/mixed hearing loss or single sided deafness.
- Conditions
- Conductive Hearing Loss, Mixed Hearing Loss, Single Sided Deafness
- Trial name
- NCT02064478
- Where
- Netherlands
- Volunteers
- 25 people
- Sponsor
- Oticon Medical