Clinical trials: Bone Pain
Lumbar Spinal Stenosis, Low Back Pain
Misoprostol for Spinal Stenosis
This single-group cross-sectional cohort study will enroll approximately 25 patients at the North Texas VA Health Care System (VANTHCS) who have previously received off-label prescriptions of misoprostol for lumbar spinal…
- Trial name
- NCT04611464
- Testing
- Misoprostol
- Where
- United States
- Volunteers
- 23 people
- Sponsor
- Dallas VA Medical Center
Breast Cancer, Bone Metastasis
Chemoradiation for Bone Metastasis
Pain from bone metastases of breast cancer origin is treated with localized radiation. Modulating doses and schedules has shown little efficacy in improving results.
- Conditions
- Breast Cancer, Bone Metastasis, Pain
- Trial name
- NCT01784393
- Testing
- chemoradiation
- Where
- Israel
- Volunteers
- 29 people
- Sponsor
- Rabin Medical Center
Rib Fractures, Pain, Chest
Kinesiotaping Method for Rib Fractures
Kinesiotaping is used as a physiotherapy method to reduce muscle pain. In this technique, kinesiotaping tapes are attached to the relevant parts of the body. Patients experience serious pain in rib fractures.
- Trial name
- NCT06222320
- Testing
- Kinesiotaping, Painkillers
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Kastamonu University
Bone Metastases, Radiotherapy Side Effect
A Prospective Randomized Trial of High Dose Versus Standard Dose Stereotactic Radiotherapy for Pain Control in Patients With Bone Metastases
In the present study, we will prospectively evaluate the pain response and treatment failure rate to determine the most favorable radiation dose in single fraction stereotactic radiotherapy using the modern highly conformal…
- Trial name
- NCT04063254
- Testing
- Stereotactic Radiotherapy
- Volunteers
- 302 people, healthy volunteers welcome
- Sponsor
- National Taiwan University Hospital
Rib Fractures, Rib Fracture Multiple
Ketamine vs Lidocaine in Traumatic Rib Fractures
Rib fractures continue to be a common occurrence in trauma patients of all ages. Traumatic rib fractures can cause severe pain in patients and lead to shallow breathing and further complications such as the need for mechanical…
- Conditions
- Rib Fractures, Rib Fracture Multiple, Rib Trauma
- Trial name
- NCT04781673
- Testing
- Ketamine, Lidocaine
- Where
- United States
- Volunteers
- 74 people
- Sponsor
- Brittany Hoyte
Breast Cancer, Hypercalcemia of Malignancy
Comparison of Two Schedules of Zoledronic Acid in Treating Patients With Breast Cancer That Has Spread to the Bone
RATIONALE: Zoledronic acid may help decrease the risk of broken bones, bone pain, and other symptoms caused by bone metastases. It may also help patients live more comfortably.
- Conditions
- Breast Cancer, Hypercalcemia of Malignancy, Metastatic Cancer, Musculoskeletal Complications
- Trial name
- NCT00458796
- Testing
- zoledronic acid, quality-of-life assessment
- Where
- 30 sites in United Kingdom
- Volunteers
- 1,500 people
- Sponsor
- University of Leeds
Pain Management, Rib Fracture Multiple
Assessment of Morbidity and Mortality Following Serratus Anterior Plane Block (SAPB) for Unilateral Rib Fractures
The goal of this observational study is to learn about the long-term effects of the serratus anterior plane block (SAPB) in adult patients who suffered multiple unilateral anterolateral rib fractures within 24 hours of patient…
- Conditions
- Pain Management, Rib Fracture Multiple, Serratus Anterior Plane Block
- Trial name
- SAPB (NCT07032766)
- Where
- United States
- Volunteers
- 220 people
- Sponsor
- Albert Einstein College of Medicine
Urolithiasis, Renal Colic
Metabolic Workup in Patients Suffering From Kidney Stone Disease and Osteopenia
Patients suffering from acute renal colic are evaluated by non contrast computerized tomography with excellent identification rates of urinary stones.
- Conditions
- Urolithiasis, Renal Colic, Osteopenia
- Trial name
- NCT04080973
- Testing
- CT scan, 24 hour urine collection
- Where
- Israel
- Volunteers
- 150 people
- Sponsor
- Ziv Hospital
Bone Metastasis, Oncology Pain
Spinal Palliation in Irradiation for Neoplastic Analgesia and Life Quality
The goal of this clinical trial is to assess the impact of reducing the volume of palliative metastatic bone irradiation on analgesic effectiveness at day 30 and to evaluate the efficiency of telemonitoring in identifying…
- Trial name
- SPINAL (NCT06884332)
- Testing
- Sparing irradiation, Conventional spinal irradiation
- Where
- 4 sites in France
- Volunteers
- 598 people
- Sponsor
- Institut de Cancérologie de Lorraine
Pain, Postoperative, Ankle Fractures
Efficacy of Multimodal Periarticular Injections in Operatively Treated Ankle Fractures
The purpose of this study is to determine the efficacy and safety of a peri-articular multimodal injection for post-operative pain control following operative management of closed, rotational ankle fractures.
- Trial name
- NCT02967172
- Testing
- Ropivacaine, Epinephrine, Morphine
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- University of Iowa
Spine Fusion, Lumbar Disc Herniation
Examination of the Effect of Early Mobilization on Postoperative Recovery, Pain, Quality of Life and Complication Development in Elective Minimally Invasive Spine Surgery
Accelerated Postoperative Recovery (ERAS) is a multidisciplinary approach aimed at facilitating faster and more effective recovery for patients undergoing surgical procedures.
- Conditions
- Spine Fusion, Lumbar Disc Herniation, Cervical Disc Disease
- Trial name
- NCT06102681
- Testing
- intervention group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people
- Sponsor
- Duzce University
EARLY UNDIFFERENTIATED SPONDYLARTHROPATHIES
French Cohort of Undifferentiated Spondyloarthritis
This study is a large national multicenter, longitudinal, prospective follow-up of patients presenting with early inflammatory back pain in order to set up a database to facilitate several investigations on diagnosis, prognosis…
- Trial name
- DESIR (NCT01648907)
- Testing
- Imaging exams
- Where
- France
- Volunteers
- 708 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Unnecessary Procedures, Low Back Pain
Promoting Patient-Centered Counseling to Reduce Inappropriate Diagnostic Tests
In this study, the investigators will develop and evaluate a novel intervention using standardized patients (SPs) -- or actors playing the roles of patients -- to enhance physicians' patient-centered counseling skills regarding…
- Conditions
- Unnecessary Procedures, Low Back Pain, Osteoporosis, Headache
- Trial name
- NCT01808664
- Testing
- Standardized Patient Instructor Intervention, Control
- Volunteers
- 61 people
- Sponsor
- University of California, Davis
Intervertebral Disc Protrusion
Mulligan SNAG Technique in Individuals With Lumbar Intervertebral Disc Protrusion
This study aimed to examine the effects of the Mulligan SNAG mobilization technique, applied in addition to conventional physiotherapy on the structure of the intervertebral disc and physical functioning in patients diagnosed…
- Trial name
- NCT06521294
- Testing
- Mulligan SNAG mobilization tecnique, Conventional Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 38 people
- Sponsor
- Biruni University
Scoliosis
Continuous Local Infusion of Anesthetic at the Incisional Site for Scoliosis Surgery
The purpose of this study is to evaluate the effects of continuous local anesthetic delivery on the immediate post-op recovery of patients undergoing spinal fusion surgery for congenital or idiopathic scoliosis.
- Trial name
- NCT00508066
- Testing
- Bupivacaine, Normal Saline
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Shriners Hospitals for Children
Multiple Myeloma
Prospective Cohort of Single-dose Radiotherapy for Painful Bone Lesions in Multiple Myeloma
Multiple myeloma is a plasma cell neoplasm that can cause painful bone lesions. The main treatment for these lesions and pain control is radiotherapy, usually in daily fractions.
- Trial name
- NCT05996367
- Testing
- Single-dose involved-site radiotherapy
- Where
- Brazil
- Volunteers
- 50 people
- Sponsor
- Instituto do Cancer do Estado de São Paulo
Hip Arthroplasty, Postoperative Pain
Comparison of Pericapsular Nerve Group+ Lateral Femoral Cutaneous Nerve Block Versus Lumbar Erector Spinae Plane Block in Hip Arthroplasty Surgery
Hip replacement surgery (partial or total hip arthroplasty) is commonly performed in elderly patients and is associated with significant postoperative pain.
- Conditions
- Hip Arthroplasty, Postoperative Pain, Hip Fractures, Postoperative Delirium (POD)
- Trial name
- NCT07445009
- Testing
- PENG + LFCN Block, PENG + Lumbar ESP Block
- Where
- Turkey (Türkiye)
- Volunteers
- 62 people
- Sponsor
- Fatih Sultan Mehmet Training and Research Hospital
Bone Metastases
MR Guided Focused Ultrasound vs Radiotherapy for Palliative Pain Tx in Bone Metastases
This is a prospective, single-center, randomized study directly comparing outcomes after MR guided high intensity focused ultrasound (MR HIFU) or external beam radiation therapy (EBRT) treatment of painful bone metastases.
- Trial name
- NCT05250687
- Testing
- MR- High intensity focused ultrasound, External beam radiotherapy
- Where
- United States
- Sponsor
- Stanford University
Postoperative Pain, Rebound Pain
Nerve Block Resolution Time Display and Pain Complaints
This randomized prospective study will evaluate whether displaying the expected nerve block resolution time on a patient's splint reduces postoperative pain-related complaints after orthopedic surgery.
- Conditions
- Postoperative Pain, Rebound Pain, Fracture
- Trial name
- NCT07887516
- Testing
- Physical display
- Volunteers
- 128 people
- Sponsor
- Medical University of South Carolina
Distal Radius Fracture
Effect of NSAID Use on Pain and Opioid Consumption Following Distal Radius Fracture
Non-steroidal anti-inflammatory drugs (NSAIDs), such as ibuprofen, are excellent medications for providing pain control in certain patients.
- Trial name
- Adult NSAID (NCT03749616)
- Testing
- Ibuprofen, Acetaminophen
- Where
- United States
- Volunteers
- 32 people
- Sponsor
- University of Missouri-Columbia
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