Clinical trials: Bone Strength
Aging, Physical Fitness
Myogenic and Osteogenic Responses to eXercise and Ibuprofen
The purpose of this study is to determine if the use of ibuprofen blocks the benefits of exercise to build bone and muscle mass.
- Trial name
- MOXI (NCT00462722)
- Testing
- Ibuprofen, musculoskeletal-loading exercise
- Where
- United States
- Volunteers
- 159 people, healthy volunteers welcome
- Sponsor
- University of Colorado, Denver
Osteoporosis in Post-menopausal Women
Bone Health in Postmenopausal Women: The Effect of Exercise With or Without Medication for Osteoporosis
Osteoporosis is a systemic bone disorder characterised by a reduced bone mass and structural deterioration, increasing the risk of fragility fractures, particularly in women post-menopause.
- Trial name
- BEAT-OP (NCT07267325)
- Testing
- EXERCISE TRAINING, Antiresorptive medication (routine clinical care)
- Where
- United Kingdom
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Loughborough University
Type1diabetes
Skeletal Fragility in Type 1 Diabetes: Glycemic Control and Bone Strength
The purpose of this research study is to find out how bones are affected in children and adolescents with type 1 diabetes (T1D) as compared to children and adolescents without type 1 diabetes.
- Trial name
- NCT04289727
- Where
- United States
- Volunteers
- 86 people, healthy volunteers welcome
- Sponsor
- Columbia University
Metabolic Bone Disease, Transplant-Related Disorder
Assessment of Vertebral Fracture Risk for First Time Liver Transplant Candidates
The researchers are trying to compare the effectiveness of Vertebral Fracture Assessment (VFA) in addition to the current standard of care spine x-ray in evaluation pre-liver transplant patients.
- Conditions
- Metabolic Bone Disease, Transplant-Related Disorder, Secondary Osteoporosis
- Trial name
- VFA (NCT03811873)
- Testing
- Dual x-ray absorptiometry, Vertebral Fracture Assessment
- Where
- United States
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Sedentary Lifestyle, Postmenopausal Women
Health Benefits of a 6-month Brisk Walking Program in Sedentary Postmenopausal Women
Community-dwelling women aged 55 or over are recruited at public meetings aimed at promoting physical activity in postmenopausal women.
- Trial name
- ACTIMARCH (NCT02094144)
- Testing
- Brisk walking program, physical activity habit
- Where
- France
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
Sciatic Leg Pain, Hamstring Muscle Tightness
Acute Effects of Neurodynamics on Strength and Endurance in Athletes
This study explores the acute effects of neurodynamics, an intervention commonly used by physical therapist to improve nerve mobility and decrease pain, on the strength and muscular endurance in the athletic population.
- Conditions
- Sciatic Leg Pain, Hamstring Muscle Tightness, Hamstring Muscle Strain, Hamstring Muscle Strength
- Trial name
- NCT07721220
- Testing
- Sciatic Slider, Sciatic Tensioner, Mechanically loaded neurodynamic sciatic floss
- Where
- United States
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- High Point University
Bone Health, Osteoporosis
Effects of Yoga on Bone Metabolism in Premenopausal Women
This study examined the effects of 8 months of Yoga training on bone density and bone turnover markers in premenopausal women, ages 35-50 years.
- Trial name
- NCT02163668
- Testing
- Yoga Group
- Where
- United States
- Volunteers
- 47 people, healthy volunteers welcome
- Sponsor
- University of Oklahoma
Bone Mineral Density, Grip Strength
Reference Curve on Bone Mineral Density in Men
In men, the hope of lower life, the absence of equivalent of menopause and the existence of a higher peak bone mass are the three factors that explain the lower incidence of osteoporosis in men.
- Conditions
- Bone Mineral Density, Grip Strength, Physical Performance
- Trial name
- COURDO2 (NCT03400982)
- Testing
- Bone densitometry measurement
- Where
- 3 sites in France
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Régional d'Orléans
Type-1 Diabetes
Canadian Bone Strength Development Study
The goal of this project is to learn about differences in bone development between children with and without type-1 diabetes (T1D). The main questions this study aims to answer are: 1.
- Trial name
- CanBSDS (NCT06287840)
- Where
- Canada
- Volunteers
- 204 people, healthy volunteers welcome
- Sponsor
- University of Saskatchewan
MACS Syndrome
MACS and Healthy Volunteers Bone Study
Adrenal adenoma is detected in 5-7% of adults and demonstrates mild autonomous cortisol secretion (MACS, dexamethasone suppression test >1.8 mcg/dl) in 50% of individuals with adenoma.
- Trial name
- NCT04343560
- Where
- United States
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Mayo Clinic
Osteoporosis, Sarcopenia
The Effect of 6 Months of Local Vibration Training in Institutionalized Elderly
This randomized controlled intervention study in institutionalized elderly investigates the effect of 6 months of local vibration therapy applied on the thigh and hip on muscle strength, muscle mass, bone density, and…
- Trial name
- NCT01499186
- Testing
- Local Vibration
- Where
- Belgium
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Universitaire Ziekenhuizen KU Leuven
Infant Development
Effects of an Infant Formula on Growth, Safety and Efficacy for Healthy Term Infants
The purpose of this study is to evaluate that a Cow's Milk Based Infant Formula A2 Containing Both OPO and CPP for healthy term infants supports age-appropriate growth.
- Trial name
- NCT04749290
- Testing
- Study Formula
- Where
- 2 sites in China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Bunge Loders Croklaan
Musculoskeletal and Connective Tissue Disorders
Effects of a School-based Exercise Program on Posture, Trunk Range of Motion, and Musculoskeletal Pain
The objective of this study was to evaluate the effects of a school-based exercise program on posture, trunk range of motion and musculoskeletal pain in schoolchildren. This study was a Randomized controlled trial.
- Trial name
- NCT02255695
- Testing
- School-based exercise program
- Where
- Brazil
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Universidade Federal de Sao Carlos
Rheumatoid Arthritis (RA), Ankylosing Spondylitis (AS)
An Investigation of the Effect of Smartphone Usage Levels on Cervical Posture, Tongue Pressure, Balance, and Neck Disability in Individuals With Rheumatoid Arthritis and Ankylosing Spondylitis
The purpose of this cross-sectional and comparative study is to investigate the impact of smartphone addiction on the cervical posture, musculoskeletal system, balance, and tongue pressure in individuals diagnosed with Rheumatoid…
- Conditions
- Rheumatoid Arthritis (RA), Ankylosing Spondylitis (AS), Forward Head Posture
- Trial name
- NCT07627542
- Where
- Turkey (Türkiye)
- Volunteers
- 111 people, healthy volunteers welcome
- Sponsor
- Merve Şahin
Elbow Fractures
Effect of CHRIST on Function and ROM in Post Fracture rehabIlitation
The main objective of the study is to find the effects of comprehensive hand repetitive intensive strength training on range of motion and function in post fracture rehabilitation to answer the question such as Does CHRIST…
- Trial name
- NCT07729878
- Testing
- Comprehensive Hand Repetitive Intensive Strength Training
- Where
- Pakistan
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Osteoporosis, Breast Cancer
Effects of Exemestane on Bone Strength
The NCIC CTG was conducting an international breast cancer prevention trial (MAP.3) examining the effects of a new therapy (exemestane) for breast cancer prevention in postmenopausal women at increased risk of developing this…
- Trial name
- MAP3BSS (NCT01144468)
- Where
- 4 sites in United States, Canada
- Volunteers
- 351 people, healthy volunteers welcome
- Sponsor
- University Health Network, Toronto
Personal Satisfaction
The Effects of Dietary Palmitic Acid Triacylglyceride Position on Bone Strength Parameters in Infants
The purpose of this study is to determine the effect of high sn-2 palmitic acid based infant formula on bone strength parameters.
- Trial name
- InFat_002 (NCT00874068)
- Testing
- InFat™ based infant formula, Standard vegetable oil based infant formula
- Where
- Israel
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Enzymotec
Healthy Volunteers, Growth Hormone Deficiency
A Study to Compare the Uptake Into the Blood of Two Strengths of Somapacitan After Injection Under the Skin in Healthy Subjects
This study will compare two strengths of the new long-acting growth hormone somapacitan. The aim of this study is to test if both strengths are taken up in the blood in the same way.
- Trial name
- NCT03905850
- Testing
- somapacitan
- Where
- Germany
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Novo Nordisk A/S
Osteoporosis
Assessment of Bone Micro-Architecture Using HR-pQCT
In the context of male osteoporosis, we hypothesize that regional changes in trabecular bone, as well as changes in cortical porosity will play a major role, and thus also affect bone strength.
- Trial name
- NCT01367730
- Where
- United States
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco
Bone Density, Muscle Weakness
Whole Body Vibration in Middle Aged Men
This study aims of this clinical trial is to evaluate the effect of an 8-week Whole Body Vibration (WBV) intervention on Bone Mineral Density (BMD), hand grip strength, and vitamin D levels in middle-aged men.
- Trial name
- NCT06644469
- Testing
- Dynatronics VF5 Model vibration platform
- Where
- Saudi Arabia
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- Jouf University